staurosporine has been researched along with alvocidib in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (10.00) | 18.2507 |
| 2000's | 23 (76.67) | 29.6817 |
| 2010's | 4 (13.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Flajolet, M; Greengard, P; Meijer, L | 1 |
| Atteridge, CE; Azimioara, MD; Benedetti, MG; Biggs, WH; Carter, TA; Ciceri, P; Edeen, PT; Fabian, MA; Floyd, M; Ford, JM; Galvin, M; Gerlach, JL; Grotzfeld, RM; Herrgard, S; Insko, DE; Insko, MA; Lai, AG; Lélias, JM; Lockhart, DJ; Mehta, SA; Milanov, ZV; Patel, HK; Treiber, DK; Velasco, AM; Wodicka, LM; Zarrinkar, PP | 1 |
| Akula, N; Pattabiraman, N; Sridhar, J | 1 |
| Atteridge, CE; Campbell, BT; Chan, KW; Ciceri, P; Davis, MI; Edeen, PT; Faraoni, R; Floyd, M; Gallant, P; Herrgard, S; Hunt, JP; Karaman, MW; Lockhart, DJ; Milanov, ZV; Morrison, MJ; Pallares, G; Patel, HK; Pritchard, S; Treiber, DK; Wodicka, LM; Zarrinkar, PP | 1 |
| Russu, WA; Shallal, HM | 1 |
| Ciceri, P; Davis, MI; Herrgard, S; Hocker, M; Hunt, JP; Pallares, G; Treiber, DK; Wodicka, LM; Zarrinkar, PP | 1 |
| Baumli, S; Endicott, JA; Fischer, PM; Hole, AJ; Huang, S; Noble, ME; Pepper, C; Shao, H; Shi, S; Wang, S | 1 |
| Das, S; Feng, X; Jeffries, C; Lang, W; Ling, T; Maier, J; Rivas, F; Shelat, A | 1 |
| Byrd, JC; Grever, MR; Rai, KR; Sausville, EA | 1 |
| Meijer, L | 1 |
| Détivaud, L; Doerig, C; Gray, N; Meijer, L | 1 |
| Sausville, EA; Senderowicz, AM | 1 |
| Damiens, E; Meijer, L | 1 |
| Andreeff, M; Kitada, S; Reed, JC; Zapata, JM | 1 |
| Bibb, JA; Biernat, J; Eisenbrand, G; Garnier, M; Greengard, P; Hoessel, R; Leclerc, S; Mandelkow, EM; Marko, D; Meijer, L; Snyder, GL; Wu, YZ | 1 |
| Senderowicz, AM | 6 |
| Nishio, K | 1 |
| Howard, OM; Kim, HH; Lin, TS; Neuberg, DS; Shipp, MA | 1 |
| Cheson, BD | 1 |
| Sausville, EA | 1 |
| Swanton, C | 1 |
| Blagden, S; de Bono, J | 1 |
| Albanese, C; D'Amico, M; Mani, S; Pestell, RG; Wang, C; Wu, K | 1 |
| Chen, XG; Zuo, MX | 1 |
| Karp, J | 1 |
19 review(s) available for staurosporine and alvocidib
| Article | Year |
|---|---|
Pharmacological inhibitors of glycogen synthase kinase 3.
Topics: Animals; Cell Differentiation; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Humans; Neoplasms; Nervous System Diseases; Parasitic Diseases; Signal Transduction; Stem Cells; Structure-Activity Relationship | 2004 |
Selectivity and potency of cyclin-dependent kinase inhibitors.
Topics: Animals; Binding Sites; Cyclin-Dependent Kinases; Humans; Protein Kinase Inhibitors; Signal Transduction | 2006 |
Old and new therapies in chronic lymphocytic leukemia: now is the time for a reassessment of therapeutic goals.
Topics: Alkaloids; Antineoplastic Agents, Alkylating; Bryostatins; Flavonoids; Humans; Lactones; Leukemia, Lymphocytic, Chronic, B-Cell; Macrolides; Piperidines; Staurosporine; Topoisomerase I Inhibitors | 1998 |
Chemical inhibitors of cyclin-dependent kinases.
Topics: 4-Butyrolactone; Animals; Cell Cycle; Cyclin-Dependent Kinases; Enzyme Inhibitors; Flavonoids; Humans; Kinetin; Piperidines; Purines; Staurosporine; Suramin | 1995 |
ATP-site directed inhibitors of cyclin-dependent kinases.
Topics: Adenine; Adenosine Triphosphate; Amino Acid Sequence; Antineoplastic Agents; Binding Sites; Cell Cycle; Cyclin-Dependent Kinases; Drug Design; Enzyme Inhibitors; Flavonoids; Humans; Isopentenyladenosine; Kinetin; Molecular Sequence Data; Piperidines; Purines; Roscovitine; Sequence Alignment; Sequence Homology, Amino Acid; Staurosporine; Suramin | 1999 |
Preclinical and clinical development of cyclin-dependent kinase modulators.
Topics: Alkaloids; Animals; Antineoplastic Agents; Cell Cycle; Clinical Trials as Topic; Cyclin-Dependent Kinases; Enzyme Inhibitors; Flavonoids; Humans; Neoplasms; Piperidines; Staurosporine | 2000 |
[Chemical inhibitors of cyclic-dependent kinases: preclinical and clinical study].
Topics: Animals; Antineoplastic Agents; Benzazepines; Cyclin-Dependent Kinases; Enzyme Inhibitors; Flavonoids; Humans; Indoles; Piperidines; Purines; Staurosporine | 2000 |
Development of cyclin-dependent kinase modulators as novel therapeutic approaches for hematological malignancies.
Topics: Alkaloids; Cell Cycle; Clinical Trials as Topic; Cyclin-Dependent Kinases; Enzyme Inhibitors; Flavonoids; Hematologic Neoplasms; Humans; Piperidines; Retinoblastoma Protein; Signal Transduction; Staurosporine | 2001 |
[CDK inhibitors for therapy of cancer].
Topics: Alkaloids; Animals; Cell Cycle; Cell Cycle Proteins; Cyclin-Dependent Kinases; Cyclins; Flavonoids; Humans; Piperidines; Protein Transport; Staurosporine; Stomach Neoplasms | 2001 |
Small molecule modulators of cyclin-dependent kinases for cancer therapy.
Topics: Alkaloids; Antineoplastic Agents; Apoptosis; Cell Cycle; Clinical Trials as Topic; Cyclin-Dependent Kinases; Drug Delivery Systems; Enzyme Inhibitors; Flavonoids; Humans; Piperidines; Protein Kinase C; Retinoblastoma Protein; Staurosporine | 2000 |
The cell cycle as a target for cancer therapy: basic and clinical findings with the small molecule inhibitors flavopiridol and UCN-01.
Topics: Alkaloids; Animals; Antineoplastic Agents; Cell Cycle; Clinical Trials as Topic; Cyclin-Dependent Kinases; Enzyme Inhibitors; Flavonoids; Humans; Neoplasms; Piperidines; Staurosporine | 2002 |
Hematologic malignancies: new developments and future treatments.
Topics: Adenine Nucleotides; Alemtuzumab; Alkaloids; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Antibodies, Neoplasm; Antineoplastic Agents; Apoptosis; Arabinonucleosides; Bendamustine Hydrochloride; Boronic Acids; Bortezomib; Cell Cycle; Cell Survival; Clofarabine; Cytosine; Dioxolanes; Flavonoids; Hematologic Neoplasms; Humans; Immunoconjugates; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Lymphoma, Non-Hodgkin; Multiple Myeloma; NF-kappa B; Nitrogen Mustard Compounds; Oligonucleotides, Antisense; Peptide Hydrolases; Piperidines; Protease Inhibitors; Proteasome Endopeptidase Complex; Pyrazines; Remission Induction; Rituximab; Staurosporine; Thionucleotides | 2002 |
Cyclin-dependent kinases as new targets for the prevention and treatment of cancer.
Topics: Alkaloids; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Differentiation; Clinical Trials, Phase I as Topic; Cyclin-Dependent Kinases; Drug Design; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Flavonoids; Humans; Neoplasm Proteins; Neoplasms; Piperidines; Signal Transduction; Staurosporine; Transcription, Genetic | 2002 |
Cyclin-dependent kinase modulators studied at the NCI: pre-clinical and clinical studies.
Topics: Alkaloids; Animals; Antineoplastic Agents; Clinical Trials as Topic; Cyclin-Dependent Kinases; Drug Evaluation, Preclinical; Enzyme Inhibitors; Flavonoids; Humans; National Institutes of Health (U.S.); Piperidines; Staurosporine; United States | 2003 |
Novel direct and indirect cyclin-dependent kinase modulators for the prevention and treatment of human neoplasms.
Topics: Alkaloids; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Cycle; Clinical Trials as Topic; Cyclin-Dependent Kinases; Enzyme Inhibitors; Flavonoids; Humans; Neoplasms; Piperidines; Staurosporine; Tumor Cells, Cultured | 2003 |
Cell-cycle targeted therapies.
Topics: Animals; Cell Cycle; Clinical Trials as Topic; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Enzyme Inhibitors; Flavonoids; Humans; Neoplasms; Piperidines; Staurosporine | 2004 |
Drugging cell cycle kinases in cancer therapy.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Binding Sites; Cyclin-Dependent Kinases; Flavonoids; Humans; Neoplasms; Oxazoles; Piperidines; Protein Kinase Inhibitors; Purines; Roscovitine; Staurosporine; Sulfonamides; Thiazoles | 2005 |
Inhibitors of cyclin-dependent kinase modulators for cancer therapy.
Topics: Animals; Antineoplastic Agents; Cell Cycle; Clinical Trials as Topic; Cyclin-Dependent Kinases; Flavonoids; Humans; Neoplasms; Piperidines; Protein Kinase Inhibitors; Staurosporine | 2005 |
[Research on cyclin-dependent kinase inhibitors: state of the art and perspective].
Topics: Animals; Antineoplastic Agents; Cell Cycle; Cyclin-Dependent Kinases; Cyclins; Flavonoids; Humans; Neoplasms; Piperidines; Purines; Roscovitine; Staurosporine | 2007 |
11 other study(ies) available for staurosporine and alvocidib
| Article | Year |
|---|---|
A small molecule-kinase interaction map for clinical kinase inhibitors.
Topics: Benzamides; Drug Design; Escherichia coli; Escherichia coli Proteins; Imatinib Mesylate; Microchemistry; Pharmaceutical Preparations; Piperazines; Protein Binding; Protein Interaction Mapping; Protein Kinase Inhibitors; Pyrimidines | 2005 |
A quantitative analysis of kinase inhibitor selectivity.
Topics: Binding Sites; Enzyme Activation; Humans; Phosphotransferases; Protein Binding; Protein Interaction Mapping; Protein Kinase Inhibitors; Proteome; Quantitative Structure-Activity Relationship | 2008 |
Discovery, synthesis, and investigation of the antitumor activity of novel piperazinylpyrimidine derivatives.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Molecular Structure; Piperazines; Protein Kinase Inhibitors; Protein Kinases; Pyrimidines; Stereoisomerism; Structure-Activity Relationship | 2011 |
Comprehensive analysis of kinase inhibitor selectivity.
Topics: Catalysis; Drug Design; Enzyme Stability; High-Throughput Screening Assays; Humans; Protein Binding; Protein Kinase Inhibitors; Protein Kinases; Proteomics; Signal Transduction; Substrate Specificity | 2011 |
Comparative structural and functional studies of 4-(thiazol-5-yl)-2-(phenylamino)pyrimidine-5-carbonitrile CDK9 inhibitors suggest the basis for isotype selectivity.
Topics: Cyclin-Dependent Kinase 9; Humans; Models, Molecular; Protein Kinase Inhibitors; Pyrimidines; Structure-Activity Relationship | 2013 |
Novel vitexin-inspired scaffold against leukemia.
Topics: Apigenin; Cell Cycle Checkpoints; Cell Death; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Humans; Molecular Docking Simulation; Molecular Structure; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Structure-Activity Relationship | 2018 |
Protein kinase inhibitors flavopiridol and 7-hydroxy-staurosporine down-regulate antiapoptosis proteins in B-cell chronic lymphocytic leukemia.
Topics: Alkaloids; Apoptosis; Carrier Proteins; DNA Fragmentation; DNA-Binding Proteins; Enzyme Inhibitors; Flavonoids; Humans; In Situ Nick-End Labeling; Kinetics; Leukemia, B-Cell; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Piperidines; Protein Kinase Inhibitors; Proteins; Proto-Oncogene Proteins c-bcl-2; Staurosporine; Transcription Factors; Tumor Cells, Cultured; X-Linked Inhibitor of Apoptosis Protein | 2000 |
Indirubins inhibit glycogen synthase kinase-3 beta and CDK5/p25, two protein kinases involved in abnormal tau phosphorylation in Alzheimer's disease. A property common to most cyclin-dependent kinase inhibitors?
Topics: Adenosine Triphosphate; Alkaloids; Alzheimer Disease; Animals; Antibiotics, Antineoplastic; Calcium-Calmodulin-Dependent Protein Kinases; CDC2 Protein Kinase; Cyclin B; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Dopamine and cAMP-Regulated Phosphoprotein 32; Drugs, Chinese Herbal; Enzyme Inhibitors; Flavonoids; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Indoles; Inhibitory Concentration 50; Mice; Molecular Structure; Neostriatum; Nerve Tissue Proteins; Phosphoproteins; Phosphorylation; Phosphothreonine; Piperidines; Staurosporine; tau Proteins | 2001 |
Seventy-two hour continuous infusion flavopiridol in relapsed and refractory mantle cell lymphoma.
Topics: Aged; Alkaloids; Antineoplastic Agents; Female; Flavonoids; Humans; Infusions, Intravenous; Lymphoma, Mantle-Cell; Male; Middle Aged; Piperidines; Staurosporine | 2002 |
A study of cytotoxic synergy of UCN-01 and flavopiridol in syngeneic pair of cell lines.
Topics: Antineoplastic Agents; Apoptosis; Caspase 8; Caspase 9; Caspases; Cell Survival; Collagen Type XI; Dose-Response Relationship, Drug; Drug Synergism; Flavonoids; HeLa Cells; Humans; Inhibitor of Apoptosis Proteins; Microtubule-Associated Proteins; Neoplasm Proteins; Piperidines; Protein Kinase Inhibitors; Staurosporine; Survivin; Transfection | 2005 |
Future research directions for the treatment of AML.
Topics: Antineoplastic Agents; Azacitidine; Biomedical Research; Carbazoles; Carboplatin; Cytarabine; Daunorubicin; Decitabine; Enzyme Inhibitors; Etoposide; Flavonoids; Furans; Humans; Leukemia, Myeloid, Acute; Mitoxantrone; Piperidines; Quinolones; Staurosporine; Topotecan; Tretinoin | 2008 |