Compounds > staurosporine
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staurosporine and alpha-synuclein

staurosporine has been researched along with alpha-synuclein in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (75.00)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ancolio, K; Checler, F; da Costa, CA1
Ambrosio, S; Barrachina, M; Ferrer, I; Gómez-Santos, C; Reiriz, J; Viñals, F1
Berger, K; Cookson, MR; Eberhardt, O; Engelender, S; Farrer, MJ; Gerhardt, E; Hernandez, D; Holzmann, C; Kachergus, J; Krüger, R; Li, L; Marx, FP; Riess, O; Ross, CA; Schöls, L; Schulz, JB; Strauss, KM1
Latchman, DS; Payne Smith, MD; Zourlidou, A1
Cai, ZL; Cao, BY; Huang, JZ; Liu, CF; Shi, JJ; Wang, F; Yang, F; Yang, YP; Zhang, P1
Emmanouilidou, E; Stefanis, L; Vekrellis, K; Xilouri, M1
Arndt-Jovin, DJ; Falomir-Lockhart, LJ; Flierl, A; Hesley, J; Jaenisch, R; Jovin, TM; Langston, JW; Mak, SK; Oliveira, LM; Schüle, B; Soldner, F1
Chen, YJ; Klucken, J; Vollmer, F; Xiang, W1

Other Studies

8 other study(ies) available for staurosporine and alpha-synuclein

ArticleYear
Wild-type but not Parkinson's disease-related ala-53 --> Thr mutant alpha -synuclein protects neuronal cells from apoptotic stimuli.
    The Journal of biological chemistry, 2000, Aug-04, Volume: 275, Issue:31

    Topics: Adult; alpha-Synuclein; Apoptosis; Caspases; Ceramides; Cysteine Proteinase Inhibitors; Etoposide; Humans; Mutation; Neocortex; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Parkinson Disease; Staurosporine; Synucleins; Transfection

2000
MPP+ increases alpha-synuclein expression and ERK/MAP-kinase phosphorylation in human neuroblastoma SH-SY5Y cells.
    Brain research, 2002, May-10, Volume: 935, Issue:1-2

    Topics: 1-Methyl-4-phenylpyridinium; alpha-Synuclein; Brain; Cell Survival; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase Kinases; Mitogen-Activated Protein Kinases; Nerve Tissue Proteins; Neuroblastoma; Neurons; p38 Mitogen-Activated Protein Kinases; Parkinson Disease; Phosphorylation; Staurosporine; Synucleins; Tumor Cells, Cultured; Up-Regulation

2002
Identification and functional characterization of a novel R621C mutation in the synphilin-1 gene in Parkinson's disease.
    Human molecular genetics, 2003, Jun-01, Volume: 12, Issue:11

    Topics: Acetylcysteine; Adult; Aged; alpha-Synuclein; Amino Acid Sequence; Carrier Proteins; Case-Control Studies; Cell Death; Cells, Cultured; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Female; Green Fluorescent Proteins; Humans; Luminescent Proteins; Male; Middle Aged; Molecular Sequence Data; Multienzyme Complexes; Mutation; Nerve Tissue Proteins; Neurons; Parkinson Disease; Proteasome Endopeptidase Complex; Recombinant Fusion Proteins; Staurosporine; Synucleins; Ubiquitin-Protein Ligases

2003
HSP27 but not HSP70 has a potent protective effect against alpha-synuclein-induced cell death in mammalian neuronal cells.
    Journal of neurochemistry, 2004, Volume: 88, Issue:6

    Topics: alpha-Synuclein; Animals; Apoptosis; Caspase Inhibitors; Cell Hypoxia; Cell Line; Cricetinae; Culture Media, Serum-Free; Cytoprotection; Dopamine; Enzyme Inhibitors; Gene Transfer Techniques; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Humans; In Situ Nick-End Labeling; Mice; Molecular Chaperones; Mutation; Neoplasm Proteins; Nerve Tissue Proteins; Neurons; Rabbits; Rats; Staurosporine; Synucleins; Tacrolimus Binding Proteins

2004
MPP+ impairs autophagic clearance of alpha-synuclein by impairing the activity of dynein.
    Neuroreport, 2009, Apr-22, Volume: 20, Issue:6

    Topics: 1-Methyl-4-phenylpyridinium; alpha-Synuclein; Animals; Autophagy; Catalase; Cytoplasm; Dyneins; Enzyme Inhibitors; Lysosomal Membrane Proteins; Lysosomes; Microtubule-Associated Proteins; Neurons; PC12 Cells; Rats; RNA, Messenger; Staurosporine; Superoxide Dismutase

2009
Inducible over-expression of wild type alpha-synuclein in human neuronal cells leads to caspase-dependent non-apoptotic death.
    Journal of neurochemistry, 2009, Volume: 109, Issue:5

    Topics: alpha-Synuclein; Amino Acid Chloromethyl Ketones; Apoptosis; bcl-X Protein; Caspases; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cytochromes c; Enzyme Inhibitors; Gene Expression Regulation; Green Fluorescent Proteins; Humans; Inositol; Membrane Potential, Mitochondrial; Mitochondria; Neuroblastoma; Staurosporine; Time Factors; Transfection; Tretinoin

2009
Higher vulnerability and stress sensitivity of neuronal precursor cells carrying an alpha-synuclein gene triplication.
    PloS one, 2014, Volume: 9, Issue:11

    Topics: alpha-Synuclein; Apoptosis; Cell Differentiation; Cell Survival; Cells, Cultured; Cellular Senescence; Culture Media; Energy Metabolism; Female; Gene Duplication; Gene Expression Regulation; Glucose; Humans; Hydrogen Peroxide; Induced Pluripotent Stem Cells; Male; Membrane Potential, Mitochondrial; Mitochondria; Neural Stem Cells; Parkinson Disease; RNA, Small Interfering; Staurosporine; Substantia Nigra

2014
Tracking micro-optical resonances for identifying and sensing novel procaspase-3 protein marker released from cell cultures in response to toxins.
    Nanotechnology, 2016, Apr-22, Volume: 27, Issue:16

    Topics: alpha-Synuclein; Biomarkers; Biosensing Techniques; Caspase 3; Cell Culture Techniques; Cell Line; Cell Survival; Gene Expression Regulation; HEK293 Cells; Humans; Rotenone; Staurosporine

2016