Compounds > staurosporine
Page last updated: 2024-08-23

staurosporine and ag-490

staurosporine has been researched along with ag-490 in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's3 (42.86)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chang, CJ; Geahlen, RL1
Chandraratna, RA; Nagpal, S; Thacher, SM; Tsang, KY; Vasudevan, J1
Bullock, AN; Fedorov, O; Knapp, S; Marsden, B; Müller, S; Pogacic, V; Rellos, P; Schwaller, J; Sundström, M1
Augustin, M; Davies, SP; Gao, Y; Harvey, KJ; Kovelman, R; Patel, UA; Woodward, A1
Hiraguri, M; Iwamoto, I; Kurasawa, K; Miike, S; Saito, Y; Sano, H1
Jane, EP; Pollack, IF; Premkumar, DR1
Hagiwara, T; Hamano, S; Ishii, M; Mori, Y; Negoro, T; Shimizu, S; Takahashi, N; Toda, T; Wakamori, M; Yonezawa, R; Yoshida, T1

Reviews

2 review(s) available for staurosporine and ag-490

ArticleYear
Protein-tyrosine kinase inhibition: mechanism-based discovery of antitumor agents.
    Journal of natural products, 1992, Volume: 55, Issue:11

    Topics: Animals; Antineoplastic Agents; Drug Screening Assays, Antitumor; Humans; Protein-Tyrosine Kinases

1992
New dermatological agents for the treatment of psoriasis.
    Journal of medicinal chemistry, 2001, Feb-01, Volume: 44, Issue:3

    Topics: Administration, Topical; Anti-Inflammatory Agents; Cholecalciferol; Clinical Trials as Topic; Glucocorticoids; Humans; Immunosuppressive Agents; Ligands; Methotrexate; Psoriasis; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Vitamin A

2001

Other Studies

5 other study(ies) available for staurosporine and ag-490

ArticleYear
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Dec-18, Volume: 104, Issue:51

    Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases

2007
A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.
    The Biochemical journal, 2013, Apr-15, Volume: 451, Issue:2

    Topics: Aurora Kinases; Cluster Analysis; Drug Design; Drug Discovery; Drug Evaluation, Preclinical; ErbB Receptors; Humans; Intracellular Signaling Peptides and Proteins; MAP Kinase Kinase 4; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptors, Vascular Endothelial Growth Factor; Recombinant Proteins; Reproducibility of Results; Signal Transduction; Small Molecule Libraries; Structure-Activity Relationship; Syk Kinase

2013
Granulocyte-macrophage colony-stimulating factor and IL-5 activate mitogen-activated protein kinase through Jak2 kinase and phosphatidylinositol 3-kinase in human eosinophils.
    The Journal of allergy and clinical immunology, 1997, Volume: 100, Issue:6 Pt 2

    Topics: Androstadienes; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Eosinophils; Genistein; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-5; Janus Kinase 2; Nitriles; Phosphatidylinositol 3-Kinases; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Signal Transduction; Staurosporine; Tyrphostins; Wortmannin

1997
AG490 influences UCN-01-induced cytotoxicity in glioma cells in a p53-dependent fashion, correlating with effects on BAX cleavage and BAD phosphorylation.
    Cancer letters, 2007, Nov-08, Volume: 257, Issue:1

    Topics: Annexin A5; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; bcl-2-Associated X Protein; bcl-Associated Death Protein; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Synergism; Genes, p53; Glioma; Humans; Poly(ADP-ribose) Polymerases; Signal Transduction; Staurosporine; Tumor Suppressor Protein p53; Tyrphostins

2007
Inhibitory effects of AG490 on H2O2-induced TRPM2-mediated Ca(2+) entry.
    European journal of pharmacology, 2014, Nov-05, Volume: 742

    Topics: Benzimidazoles; Calcium Channels; Calcium Signaling; Enzyme Inhibitors; Free Radical Scavengers; HEK293 Cells; Humans; Hydrogen Peroxide; Janus Kinase 1; Janus Kinase 2; Nerve Tissue Proteins; Oxidative Stress; Patch-Clamp Techniques; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Pyridones; Reactive Oxygen Species; Recombinant Proteins; Staurosporine; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPM Cation Channels; Tyrphostins; U937 Cells

2014