staurosporine has been researched along with 1-hexadecyl-2-acetyl-glycero-3-phosphocholine in 47 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (8.51) | 18.7374 |
| 1990's | 43 (91.49) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Akkerman, JW; van Willigen, G | 1 |
| Bach, MK; Brashler, JR; Petzold, EN; Sanders, ME | 1 |
| Müller, S; Nigam, S | 2 |
| Fernandez-Gallardo, S; Guntaka, RV; Kandala, JC; Lim, RW; Shukla, SD; Tripathi, YB | 1 |
| Joseph, S; MacDermot, J | 1 |
| Fujii, T; Hashizume, T; Sato, T | 1 |
| Arata, Y; Kume, S; Tada, S; Ui, M; Yatomi, Y | 1 |
| Becker, EL; Huang, CK; Molski, TF; Sha'afi, RI; Stevens, T; Yamazaki, M | 1 |
| Elmore, M; Kellie, S; Murphy, CT; Westwick, J | 2 |
| Hayashi, M; Imai, Y; Oh-ishi, S | 1 |
| Baggiolini, M; Dahinden, CA; Deranleau, DA; Kernen, P; Spry, CJ; Tai, PC; von Tscharner, V; Wymann, MP | 1 |
| Gimbrone, MA; Hrbolich, JK; Schafer, AI; Zavoico, GB | 1 |
| Béréziat, G; Cherqui, G; Etienne, J; Kadiri, C; Masliah, J; Rybkine, T | 1 |
| Benveniste, J; Bessou, G; Bossant, MJ; Joly, F; Ninio, E; Vigrain, I | 1 |
| Combadière, C; Giroud, JP; Hakim, J; Périanin, A | 1 |
| Grinstein, S; Lu, DJ | 1 |
| Koenderman, L; Roos, D; Tool, AT; Verhoeven, AJ | 1 |
| Levine, L | 1 |
| Jacobson, D; O'Flaherty, JT | 1 |
| Koenderman, L; Roos, D; Tool, A; Verhoeven, AJ | 1 |
| Arese, P; Bussolino, F; Fischer, E; Kazatchkine, MD; Turrini, F | 1 |
| Dhar, A; Morrison, WJ; Shukla, SD | 1 |
| Turner, NC; Wood, LJ | 1 |
| Bennett, SA; Birnboim, HC | 2 |
| Eskafi, S; Müller, S; Nigam, S; Zhang, H | 1 |
| Hoshi, H; Masuda, T; Sasaki, H; Shimura, S; Shirato, K; Yamaya, M | 1 |
| Inagami, T; Inui, H; Kitami, Y; Kondo, T; Konishi, F | 1 |
| Dohi, T; Kitayama, S; Morita, K; Okamoto, H; Shibata, K; Shirakawa, M | 1 |
| Ali, H; DuBose, RA; Haribabu, B; Richardson, RM; Snyderman, R; Tomhave, ED | 1 |
| Barnes, PJ; Giembycz, MA; Kroegel, C; Matthys, H; Westwick, J | 1 |
| James-Kracke, MR; Sexe, RB; Shukla, SD | 1 |
| Alverez, J; Garcia-Sancho, J; Montero, M | 1 |
| Blom, M; Koenderman, L; Kok, PT; Lammers, JW; Raaijmakers, JA; van der Bruggen, T; Verhoeven, AJ | 1 |
| Akkerman, JW; Burgers, JA | 1 |
| Hawkins, PT; Jackson, T; Stephens, L | 1 |
| Koenderman, L; Lammers, JW; Maikoe, T; Raaijmakers, JA; Schweizer, RC; van Kessel-Welmers, BA; Warringa, RA | 1 |
| Akkerman, JW; Gorter, G; Hers, I; van Willigen, G | 1 |
| Dohi, T; Kitayama, S; Morita, K; Okamoto, H; Shibata, K | 1 |
| Misra, UK; Pizzo, SV | 1 |
| Burt, RP; Chapple, CR; Marshall, I | 1 |
| Ali, H; Haribabu, B; Richardson, RM; Snyderman, R | 1 |
| Giembycz, MA; Hellewell, PG; Lindsay, MA; Teixeira, MM | 1 |
| O'Neill, C | 1 |
| Egesten, A; Malm, J | 1 |
47 other study(ies) available for staurosporine and 1-hexadecyl-2-acetyl-glycero-3-phosphocholine
| Article | Year |
|---|---|
Regulation of glycoprotein IIB/IIIA exposure on platelets stimulated with alpha-thrombin.
Topics: Alkaloids; Binding Sites; Blood Platelets; Bucladesine; Epoprostenol; Fibrinogen; Fibronectins; Hirudins; Humans; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Staurosporine; Thrombin | 1992 |
Superoxide production by human eosinophils can be inhibited in an agonist-selective manner.
Topics: Alkaloids; Androstadienes; Carbazoles; Eosinophils; Humans; Immunoglobulin G; Indole Alkaloids; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Protein Kinase C; Sphingosine; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate; Wortmannin; Zymosan | 1992 |
Arachidonic acid release and platelet-activating factor formation by staurosporine in human neutrophils challenged with n-formyl peptide.
Topics: Alkaloids; Arachidonic Acid; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Protein Kinase C; Staurosporine | 1992 |
Enhancement by staurosporine of platelet-activating factor formation in N-formyl peptide-challenged human neutrophils is mediated by intracellular platelet-activating factor binding sites.
Topics: Alkaloids; Azepines; Binding Sites; Calcium; Drug Synergism; Humans; In Vitro Techniques; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Staurosporine; Triazoles | 1992 |
Involvement of tyrosine kinase and protein kinase C in platelet-activating-factor-induced c-fos gene expression in A-431 cells.
Topics: Alkaloids; Blotting, Northern; Cinnamates; Colforsin; Cycloheximide; Gene Expression; Genes, fos; Genistein; Humans; Isoflavones; Platelet Activating Factor; Protein Kinase C; Protein-Tyrosine Kinases; RNA; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Thrombin promotes actin polymerization in U937 human monocyte-macrophage cells. Analysis of the signalling mechanisms mediating actin polymerization.
Topics: Actins; Alkaloids; Calcium; Cations, Divalent; Cell Line; Chemotaxis, Leukocyte; GTP-Binding Proteins; Humans; Indoles; Ionomycin; Macrophages; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Pertussis Toxin; Platelet Activating Factor; Polymers; Protein Kinase C; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin; Virulence Factors, Bordetella | 1992 |
Sphingosine enhances platelet aggregation through an increase in phospholipase C activity by a protein kinase C-independent mechanism.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alkaloids; Animals; Arachidonic Acid; Blood Platelets; Calcium; Cell Membrane; Inositol 1,4,5-Trisphosphate; Isoquinolines; Kinetics; Piperazines; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Rabbits; Sphingosine; Staurosporine; Thrombin; Type C Phospholipases | 1992 |
Phosphorylation of the inhibitory guanine-nucleotide-binding protein as a possible mechanism of inhibition by protein kinase C of agonist-induced Ca2+ mobilization in human platelet.
Topics: Alkaloids; Amino Acid Sequence; Arginine Vasopressin; Blood Platelets; Blotting, Western; Calcium; Enzyme Activation; GTP-Binding Proteins; Humans; Molecular Sequence Data; Phosphorylation; Platelet Activating Factor; Precipitin Tests; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane A2 | 1992 |
Modulation of leukotriene B4 and platelet-activating factor binding to neutrophils.
Topics: Alkaloids; Calcium; Cell Membrane; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; In Vitro Techniques; Kinetics; Leukotriene B4; Neutrophils; Platelet Activating Factor; Protein Kinase C; Recombinant Proteins; Staurosporine; Tetradecanoylphorbol Acetate | 1991 |
Comparison of the role of protein kinase C in platelet functional responses induced by three different mechanisms, PAF, ionomycin and arachidonic acid.
Topics: Alkaloids; Animals; Arachidonic Acid; Calcium; Feedback; Ionomycin; Phosphorylation; Platelet Activating Factor; Platelet Activation; Platelet Membrane Glycoproteins; Protein Kinase C; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Serotonin; Staurosporine; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1991 |
Phorbol ester stimulates PAF synthesis via the activation of protein kinase C in rat leukocytes.
Topics: Acetyltransferases; Alkaloids; Animals; Enzyme Activation; In Vitro Techniques; Kinetics; Leukocytes; Male; Microsomes; Platelet Activating Factor; Platelet Aggregation; Protein Kinase C; Rabbits; Rats; Rats, Inbred Strains; Staurosporine; Tetradecanoylphorbol Acetate | 1991 |
The relationship between cytosolic Ca2+, sn-1,2-diacylglycerol and inositol 1,4,5-trisphosphate elevation in platelet-activating-factor-stimulated rabbit platelets. Influence of protein kinase C on production of signal molecules.
Topics: Alkaloids; Animals; Blood Platelets; Calcium; Cytosol; Diglycerides; Dose-Response Relationship, Drug; Homeostasis; Inositol 1,4,5-Trisphosphate; Kinetics; Phosphorylation; Platelet Activating Factor; Platelet Activation; Protein Kinase C; Rabbits; Staurosporine; Thromboxane B2 | 1991 |
Shape changes, exocytosis, and cytosolic free calcium changes in stimulated human eosinophils.
Topics: Alkaloids; Calcium; Complement C5a; Eosinophils; Exocytosis; Humans; Interleukin-8; N-Formylmethionine Leucyl-Phenylalanine; Peroxidases; Pertussis Toxin; Platelet Activating Factor; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors; Virulence Factors, Bordetella | 1991 |
Enhancement of thrombin- and ionomycin-stimulated prostacyclin and platelet-activating factor production in cultured endothelial cells by a tumor-promoting phorbol ester.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Arachidonic Acids; Calcimycin; Cells, Cultured; Dinoprost; Dinoprostone; Endothelium, Vascular; Epoprostenol; Humans; Ionomycin; Isoquinolines; Phorbol Esters; Phospholipases A; Phospholipases A2; Piperazines; Platelet Activating Factor; Prostaglandin D2; Prostaglandins H; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin | 1990 |
Mechanism of N-formyl-methionyl-leucyl-phenylalanine- and platelet-activating factor-induced arachidonic acid release in guinea pig alveolar macrophages: involvement of a GTP-binding protein and role of protein kinase A and protein kinase C.
Topics: Alkaloids; Animals; Arachidonic Acid; Arachidonic Acids; Down-Regulation; GTP-Binding Proteins; Guinea Pigs; Isoquinolines; Macrophages; N-Formylmethionine Leucyl-Phenylalanine; Pertussis Toxin; Platelet Activating Factor; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Pulmonary Alveoli; Staurosporine; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1990 |
Biosynthesis of paf-acether. Activators of protein kinase C stimulate cultured mast cell acetyltransferase without stimulating paf-acether synthesis.
Topics: Acetyltransferases; Alkaloids; Animals; beta-N-Acetylhexosaminidases; Bone Marrow Cells; Calcium; Chlorpromazine; Chromatography, Gas; Cytoplasmic Granules; Enzyme Activation; Immunoglobulin E; Mast Cells; Mice; Mice, Inbred BALB C; Platelet Activating Factor; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1990 |
Staurosporine, a protein kinase inhibitor, up-regulates the stimulation of human neutrophil respiratory burst by N-formyl peptides and platelet activating factor.
Topics: Alkaloids; Chemotaxis, Leukocyte; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Platelet Activating Factor; Protein Kinase C; Staurosporine; Superoxides | 1990 |
ATP and guanine nucleotide dependence of neutrophil activation. Evidence for the involvement of two distinct GTP-binding proteins.
Topics: Adenosine Triphosphate; Alkaloids; Arachidonic Acid; Arachidonic Acids; Cell Membrane Permeability; GTP-Binding Proteins; Guanine Nucleotides; Humans; In Vitro Techniques; Kinetics; Leukotriene B4; Models, Biological; Neutrophils; Oxygen Consumption; Pertussis Toxin; Platelet Activating Factor; Protein Kinase C; Staurosporine; Structure-Activity Relationship; Virulence Factors, Bordetella | 1990 |
Priming of the respiratory burst in human eosinophils is accompanied by changes in signal transduction.
Topics: Alkaloids; Calcium; Cells, Cultured; Diglycerides; Eosinophils; Humans; Oxygen Consumption; Phagocytosis; Platelet Activating Factor; Protein Kinase C; Signal Transduction; Staurosporine; Zymosan | 1990 |
Effects of the protein kinase inhibitors, staurosporine and K-252a, on PGI2 production by rat liver cells (the C-9 cell line).
Topics: 6-Ketoprostaglandin F1 alpha; Alkaloids; Animals; Calcimycin; Carbazoles; Cell Line; Drug Synergism; Epoprostenol; Indole Alkaloids; Liver; Platelet Activating Factor; Protein Kinase C; Radioimmunoassay; Rats; Staurosporine; Tetradecanoylphorbol Acetate | 1990 |
Protein kinase C blockers and neutrophil receptors for leukotriene B4.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Humans; In Vitro Techniques; Isoquinolines; Kinetics; Leukotriene B4; Neutrophils; Piperazines; Platelet Activating Factor; Protein Kinase C; Receptors, Immunologic; Receptors, Leukotriene B4; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate; Thermodynamics | 1989 |
1,2-Diacylglycerol accumulation in human neutrophils does not correlate with respiratory burst activation.
Topics: Alkaloids; Diglycerides; Glycerides; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Phagocytosis; Platelet Activating Factor; Protein Kinase C; Staurosporine | 1989 |
Platelet-activating factor enhances complement-dependent phagocytosis of diamide-treated erythrocytes by human monocytes through activation of protein kinase C and phosphorylation of complement receptor type one (CR1).
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Azo Compounds; Cell Adhesion; Complement System Proteins; Diamide; Enzyme Activation; Erythrocytes; Humans; In Vitro Techniques; Isoquinolines; Kinetics; Monocytes; Palmitoylcarnitine; Phagocytosis; Phosphorylation; Piperazines; Platelet Activating Factor; Protein Kinase C; Receptors, Complement; Sphingosine; Staurosporine; Structure-Activity Relationship | 1989 |
Staurosporine potentiates platelet activating factor stimulated phospholipase C activity in rabbit platelets but does not block desensitization by platelet activating factor.
Topics: Alkaloids; Animals; Blood Platelets; Drug Synergism; In Vitro Techniques; Inositol; Inositol Phosphates; Kinetics; Phosphorylation; Platelet Activating Factor; Protein Kinase C; Rabbits; Staurosporine; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1989 |
Superoxide generation by guinea-pig peritoneal macrophages is inhibited by rolipram, staurosporine and mepacrine in an agonist-dependent manner.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Alkaloids; Animals; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Guinea Pigs; Macrophages, Peritoneal; Male; N-Formylmethionine Leucyl-Phenylalanine; Phospholipases A; Phospholipases A2; Phosphoric Diester Hydrolases; Platelet Activating Factor; Protein Kinase C; Pyrrolidinones; Quinacrine; Respiratory Burst; Rolipram; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1994 |
Platelet activating factor induces transformation of human fibroblasts.
Topics: Alkaloids; Analysis of Variance; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Fibroblasts; Genistein; Growth Inhibitors; Humans; Indomethacin; Infant, Newborn; Isoflavones; Phospholipid Ethers; Platelet Activating Factor; Protein Kinase C; Skin; Staurosporine | 1995 |
Evidence for the predominant role of intracellular PAF binding sites in the regulation of phospholipase A2 in human neutrophils.
Topics: Alkaloids; Azepines; Humans; Indoles; Leukotriene Antagonists; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Staurosporine; Triazoles | 1995 |
Eosinophil penetration through cultured human airway epithelial cell layer.
Topics: Alkaloids; Antibodies; Cell Movement; Cells, Cultured; Eosinophils; Epithelial Cells; Epithelium; Humans; Intercellular Adhesion Molecule-1; Mannitol; Phorbol Esters; Platelet Activating Factor; Staurosporine; Trachea; Tritium | 1995 |
Participation of diacylglycerol kinase in mitogenic signal transduction induced by platelet-derived growth factor in vascular smooth muscle cells.
Topics: Alkaloids; Analysis of Variance; Animals; Aorta, Thoracic; Arachidonic Acid; Becaplermin; Cell Division; Cells, Cultured; Diacylglycerol Kinase; DNA; Enzyme Activation; Genistein; Humans; Isoflavones; Mitogens; Muscle, Smooth, Vascular; Myristic Acid; Myristic Acids; Phospholipase D; Phosphotransferases (Alcohol Group Acceptor); Platelet Activating Factor; Platelet-Derived Growth Factor; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-sis; Pyrimidinones; Rats; Recombinant Proteins; Signal Transduction; Staurosporine; Thiazoles | 1994 |
Regulation by protein kinase C of platelet-activating factor- and thapsigargin-induced calcium entry in rabbit neutrophils.
Topics: Alkaloids; Animals; Calcium; Calcium Chloride; Calcium-Transporting ATPases; Cytosol; Electrophysiology; Enzyme Activation; Inositol 1,4,5-Trisphosphate; Neutrophils; Platelet Activating Factor; Protein Kinase C; Rabbits; Spectrometry, Fluorescence; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1994 |
Regulation of stably transfected platelet activating factor receptor in RBL-2H3 cells. Role of multiple G proteins and receptor phosphorylation.
Topics: Alkaloids; Amino Acid Sequence; Animals; Bucladesine; Calcium; Cell Line; GTP-Binding Proteins; Guanosine Diphosphate; Humans; Molecular Sequence Data; Pertussis Toxin; Phosphorylation; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Staurosporine; Thionucleotides; Transfection; Virulence Factors, Bordetella | 1994 |
Modulatory role of protein kinase C on the signal transduction pathway utilized by platelet-activating factor in eosinophil activation.
Topics: Alkaloids; Animals; Azepines; Calcium; Cell Membrane; Cytosol; Eosinophil Peroxidase; Eosinophils; Guinea Pigs; Male; Peritoneal Lavage; Peroxidases; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate; Triazoles | 1994 |
Picomolar platelet-activating factor mobilizes Ca to change platelet shape without activating phospholipase C or protein kinase C; simultaneous fluorometric measurement of intracellular free Ca concentration and aggregation.
Topics: Alkaloids; Animals; Calcium; Calcium Channels; Enzyme Activation; Fluorometry; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Platelet Membrane Glycoproteins; Protein Kinase C; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Scattering, Radiation; Staurosporine; Thrombin; Type C Phospholipases | 1994 |
Chemotactic peptide down-regulation of calcium mobilization induced by platelet-activating factor and by leukotriene B4 in human neutrophils is uncovered by protein phosphatase inhibitors.
Topics: Alkaloids; Calcium; Down-Regulation; Ethers, Cyclic; Humans; Indoles; Leukotriene B4; Marine Toxins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Okadaic Acid; Oxazoles; Phorbol 12,13-Dibutyrate; Phosphoprotein Phosphatases; Phosphorylation; Platelet Activating Factor; Protein Kinase C; Signal Transduction; Staurosporine | 1994 |
Transient exposure of human eosinophils to the protein kinase C inhibitors CGP39-360, CGP41-251, and CGP44-800 leads to priming of the respiratory burst induced by opsonized particles.
Topics: Alkaloids; Calcium; Enzyme Inhibitors; Eosinophils; Humans; Opsonin Proteins; Organic Chemicals; Platelet Activating Factor; Protein Kinase C; Respiratory Burst; Staurosporine; Tetradecanoylphorbol Acetate; Zymosan | 1993 |
Regulation of the receptor for platelet-activating factor on human platelets.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alkaloids; Antimycin A; Blood Platelets; Calmodulin; Cyclic AMP; Deoxyglucose; Energy Metabolism; Humans; Phosphoproteins; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Sphingosine; Staurosporine; Sulfonamides | 1993 |
Synthesis of phosphatidylinositol 3,4,5-trisphosphate in permeabilized neutrophils regulated by receptors and G-proteins.
Topics: Adenosine Triphosphate; Alkaloids; Amino Acid Sequence; Calcium; Cell Membrane Permeability; Cells, Cultured; GTP-Binding Proteins; Humans; Kinetics; Molecular Sequence Data; Neutrophils; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Phosphates; Phosphatidylinositols; Phospholipases A; Phosphotransferases; Platelet Activating Factor; Receptors, Cell Surface; Staurosporine; Virulence Factors, Bordetella | 1993 |
Mechanisms involved in eosinophil migration. Platelet-activating factor-induced chemotaxis and interleukin-5-induced chemokinesis are mediated by different signals.
Topics: Actins; Alkaloids; Benzoquinones; Calcium; Cell Movement; Cells, Cultured; Chemotaxis, Leukocyte; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Eosinophils; Humans; Interleukin-5; Lactams, Macrocyclic; Phosphoproteins; Phosphotyrosine; Platelet Activating Factor; Protein Kinase C; Protein Kinase Inhibitors; Quinones; Rifabutin; Signal Transduction; Staurosporine | 1996 |
Exposure of ligand-binding sites on platelet integrin alpha IIB/beta 3 by phosphorylation of the beta 3 subunit.
Topics: Alkaloids; Benzoquinones; Binding Sites; Blood Platelets; Enzyme Inhibitors; Fibrinogen; Fibronectins; Humans; In Vitro Techniques; Indoles; Kinetics; Lactams, Macrocyclic; Ligands; Maleimides; Phosphorylation; Platelet Activating Factor; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Protein-Tyrosine Kinases; Quinones; Rifabutin; Staurosporine | 1996 |
Ca2+ entry induced by calcium influx factor and its regulation by protein kinase C in rabbit neutrophils.
Topics: Adrenal Glands; Alkaloids; Animals; Azepines; Calcium; Calcium Channel Blockers; Cattle; Chromaffin Granules; Enzyme Inhibitors; Imidazoles; Ion Transport; Neutrophils; Platelet Activating Factor; Protein Kinase C; Rabbits; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Triazoles | 1996 |
Ligation of the alpha 2-macroglobulin signaling receptor on macrophages induces synthesis of platelet activating factor.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Acetyltransferases; Alkaloids; alpha-Macroglobulins; Animals; Cells, Cultured; Choline; Cycloheximide; Low Density Lipoprotein Receptor-Related Protein-1; Macrophages; Mice; Mice, Inbred C57BL; Pertussis Toxin; Phospholipases A; Platelet Activating Factor; Protein Kinase C; Receptors, Immunologic; Specific Pathogen-Free Organisms; Staurosporine; Virulence Factors, Bordetella | 1996 |
The role of diacylglycerol and activation of protein kinase C in alpha 1A-adrenoceptor-mediated contraction to noradrenaline of rat isolated epididymal vas deferens.
Topics: Animals; Calcium; Carcinogens; Cyclohexanones; Diglycerides; Lipoprotein Lipase; Male; Naphthalenes; Norepinephrine; Phorbol 12,13-Dibutyrate; Platelet Activating Factor; Protein Kinase C; Pyrimidinones; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Staurosporine; Thiazoles; Vas Deferens | 1996 |
Cross-desensitization among receptors for platelet activating factor and peptide chemoattractants. Evidence for independent regulatory pathways.
Topics: Amino Acid Sequence; Calcium; Chemotactic Factors; Egtazic Acid; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Interleukin-8; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Staurosporine; Tetradecanoylphorbol Acetate | 1996 |
Pertussis toxin shows distinct early signalling events in platelet-activating factor-, leukotriene B4-, and C5a-induced eosinophil homotypic aggregation in vitro and recruitment in vivo.
Topics: Animals; Calcium; Cell Aggregation; Chemotactic Factors; Chemotaxis, Leukocyte; Complement C5a; Enzyme Inhibitors; Eosinophils; Female; GTP-Binding Proteins; Guinea Pigs; Indoles; Isoenzymes; Isoquinolines; Leukotriene B4; Pertussis Toxin; Phospholipase C beta; Platelet Activating Factor; Protein Kinase C; Signal Transduction; Staurosporine; Sulfonamides; Type C Phospholipases; Virulence Factors, Bordetella | 1997 |
Receptor-mediated and protein kinase-dependent growth enhancement of primary human fibroblasts by platelet activating factor.
Topics: Animals; Cell Division; Cells, Cultured; Culture Media, Serum-Free; Fibroblasts; Genistein; Humans; Indomethacin; Infant, Newborn; Male; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Polymerase Chain Reaction; Protein Kinase C; Protein Kinases; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Sepharose; Skin; Staurosporine; Transcription, Genetic; Up-Regulation | 1997 |
Autocrine mediators are required to act on the embryo by the 2-cell stage to promote normal development and survival of mouse preimplantation embryos in vitro.
Topics: Animals; Apoptosis; Autocrine Communication; Blastocyst; Cell Count; Cell Survival; Culture Media; Embryo, Mammalian; Embryonic and Fetal Development; Enzyme Inhibitors; Female; Mice; Platelet Activating Factor; Pregnancy; Staurosporine; Survival; Zygote | 1998 |
Eosinophil leukocyte degranulation in response to serum-opsonized beads: C5a and platelet-activating factor enhance ECP release, with roles for protein kinases A and C.
Topics: Blood Proteins; Cell Degranulation; Complement C5a; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Eosinophil Granule Proteins; Eosinophils; Humans; Naphthalenes; Platelet Activating Factor; Protein Kinase C; Ribonucleases; Staurosporine; Time Factors | 1998 |