stattic has been researched along with andrographolide* in 1 studies
1 other study(ies) available for stattic and andrographolide
Article | Year |
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Andrographolide derivative as STAT3 inhibitor that protects acute liver damage in mice.
Sustained activation of the Janus kinase-signal transducers and activators of transcription (JAK-STAT) pathway contributed to the progression of cancer and liver diseases. STAT3 signaling inhibitor has been extensively investigated for pharmacological use. We synthesized a series of andrographolide derivatives, and characterized their activity against STAT3 signaling pathway both in vitro and in the CCl Topics: Acute Lung Injury; Animals; Carbon Tetrachloride; Cells, Cultured; Diterpenes; Dose-Response Relationship, Drug; Humans; Male; Mice; Mice, Inbred BALB C; Molecular Structure; Protective Agents; Signal Transduction; STAT3 Transcription Factor; Structure-Activity Relationship | 2018 |