Page last updated: 2024-08-24

st 679 and tolmetin

st 679 has been researched along with tolmetin in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (60.00)18.2507
2000's2 (20.00)29.6817
2010's2 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Amico-Roxas, M; Attaguile, G; Caruso, A; Cutuli, VM; De Bernardis, E1
Arrigoni Martelli, E; Bruno, G; Cardace, G; Mancinelli, A; Marzo, A; Morabito, E1
Annunziato, L; di Renzo, G2
Ciarimboli, M; Donati, G; Garzya, G; Imparato, L; Lingetti, M; Nolfe, G; Porfido, FA; Saraceni, G; Sorrentino, GP1
Carminati, P; Coppelli, G; Coruzzi, G; Grandi, D; Lo Giudice, P; Longo, A; Morini, G; Pace, S; Pacifici, L; Pisano, C; Vesci, L1
Cavestro, GM; Coppelli, G; Coruzzi, G; Lo Giudice, P; Okolicsanyi, L; Pisano, C; Spaggiari, S; Tepperman, BL1
Alexandova, A; Kesiova, M; Kirkova, M; Todorov, S1
Bharathi, DV; Chatki, P; Hotha, KK; Kumar, SS; Mullangi, R; Ravindranath, LK; Reddy, YN; Veera, KN1
Li, X; Liu, D; Rong, Z; Xiang, D; Xu, Y; Zhang, C1

Trials

4 trial(s) available for st 679 and tolmetin

ArticleYear
[A bioequivalence study of tablet and powder formulations of the nonsteroidal anti-inflammatory drug 2-methoxyphenyl 1-methyl-5-(p-methylbenzoylpyrrol)-2-acetamidoacetate].
    La Clinica terapeutica, 1993, Volume: 142, Issue:1 Pt 2

    Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Female; Glycine; Humans; Male; Powders; Pyrroles; Tablets; Therapeutic Equivalency; Time Factors; Tolmetin

1993
[An evaluation of the therapeutic activity and tolerance of ST-679 in patients with osteoarthritis at different sites. A controlled double-blind study vs tolmetin].
    La Clinica terapeutica, 1993, Volume: 142, Issue:1 Pt 2

    Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Drug Interactions; Drug Tolerance; Female; Glycine; Humans; Italy; Male; Middle Aged; Osteoarthritis; Pyrroles; Time Factors; Tolmetin

1993
[A bioequivalence study in man of tablet and capsule formulations of the nonsteroidal anti-inflammatory compound 2-methoxyphenyl 1-methyl-5-(p-methylbenzoylpyrrol)-2-acetamidoacetate].
    La Clinica terapeutica, 1993, Volume: 142, Issue:1 Pt 2

    Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Capsules; Female; Glycine; Humans; Male; Pyrroles; Tablets; Therapeutic Equivalency; Time Factors; Tolmetin

1993
Validation and clinical application of an LC-ESI-MS/MS method for simultaneous determination of tolmetin and MED5, the metabolites of amtolmetin guacil in human plasma.
    Biomedical chromatography : BMC, 2010, Volume: 24, Issue:10

    Topics: Chromatography, Liquid; Drug Stability; Glycine; Humans; Linear Models; Male; Pyrroles; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Tolmetin

2010

Other Studies

6 other study(ies) available for st 679 and tolmetin

ArticleYear
Pharmacological properties and toxicology of MED-15, a prodrug of tolmetin.
    Drugs under experimental and clinical research, 1992, Volume: 18, Issue:11-12

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Female; Glycine; Lethal Dose 50; Male; Peptic Ulcer; Prodrugs; Pyrroles; Rats; Rats, Wistar; Tolmetin

1992
High-performance liquid chromatographic evaluation of Med 15 and its metabolites Med 5 and tolmetin in rat plasma.
    Journal of chromatography, 1991, Aug-16, Volume: 553, Issue:1-2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, Gas; Chromatography, High Pressure Liquid; Glycine; Male; Mass Spectrometry; Pyrroles; Rats; Rats, Inbred Strains; Spectrophotometry, Ultraviolet; Tolmetin

1991
Gastrosparing effect of new antiinflammatory drug amtolmetin guacyl in the rat: involvement of nitric oxide.
    Digestive diseases and sciences, 1999, Volume: 44, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Gastric Mucosa; Glycine; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Pyrroles; Rats; Rats, Wistar; Tolmetin

1999
Gastroprotective effects of amtolmetin guacyl: a new non-steroidal anti-inflammatory drug that activates inducible gastric nitric oxide synthase.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2002, Volume: 34, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Ethanol; Gastric Mucosa; Glycine; Lipopolysaccharides; Male; Nitric Oxide; Nitric Oxide Synthase; Peroxidase; Pyrroles; Rats; Rats, Wistar; Tolmetin

2002
In vivo effects of amtolmetin guacyl on lipid peroxidation and antioxidant defence systems. Comparison with non-selective and COX-2 selective NSAIDs.
    Autonomic & autacoid pharmacology, 2007, Volume: 27, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Catalase; Celecoxib; Colon; Cyclooxygenase 2 Inhibitors; Diclofenac; Gastric Mucosa; Glucosephosphate Dehydrogenase; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glycine; Lipid Peroxidation; Liver; Male; Oxyphenonium; Pyrazoles; Pyrroles; Rats; Rats, Wistar; Sulfhydryl Compounds; Sulfonamides; Thiobarbituric Acid Reactive Substances; Tolmetin

2007
Evaluation of intestinal absorption of amtolmetin guacyl in rats: breast cancer resistant protein as a primary barrier of oral bioavailability.
    Life sciences, 2013, Feb-27, Volume: 92, Issue:3

    Topics: Adenosine; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Availability; Diketopiperazines; Glycine; Heterocyclic Compounds, 4 or More Rings; Intestinal Absorption; Intestinal Mucosa; Leukotriene Antagonists; Male; Mice; Mice, Knockout; Propionates; Pyrroles; Quinolines; Rats; Rats, Sprague-Dawley; Tolmetin; Vasodilator Agents; Verapamil

2013