Page last updated: 2024-09-02

st 1435 and ethinyl estradiol

st 1435 has been researched along with ethinyl estradiol in 16 studies

Compound Research Comparison

Studies
(st 1435)
Trials
(st 1435)
Recent Studies (post-2010)
(st 1435)
Studies
(ethinyl estradiol)
Trials
(ethinyl estradiol)
Recent Studies (post-2010) (ethinyl estradiol)
9731339,0701,5661,732

Protein Interaction Comparison

ProteinTaxonomyst 1435 (IC50)ethinyl estradiol (IC50)
Solute carrier family 22 member 2Homo sapiens (human)2.2
Bile salt export pumpHomo sapiens (human)10
Estrogen receptorHomo sapiens (human)0.0035
Glucocorticoid receptorHomo sapiens (human)1.71
Glycine receptor subunit alpha-1Rattus norvegicus (Norway rat)1.71
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)0.959
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)5.678
Androgen receptorRattus norvegicus (Norway rat)4.8812
Glycine receptor subunit betaRattus norvegicus (Norway rat)1.71
Glycine receptor subunit alpha-2Rattus norvegicus (Norway rat)1.71
Sodium-dependent noradrenaline transporter Homo sapiens (human)0.959
Glycine receptor subunit alpha-3Rattus norvegicus (Norway rat)1.71
Sodium-dependent serotonin transporterHomo sapiens (human)0.054
Sulfotransferase 1A1Homo sapiens (human)0.02
Sodium-dependent dopamine transporter Homo sapiens (human)0.559
Aldehyde oxidaseHomo sapiens (human)0.57
Nuclear receptor subfamily 1 group I member 3 Homo sapiens (human)3
Estrogen receptor betaHomo sapiens (human)0.0129

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (12.50)18.2507
2000's7 (43.75)29.6817
2010's6 (37.50)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Alvarez-Sanchez, F; Brache, V; Faundes, A; Jackanicz, T1
Haukkamaa, M; Heikinheimo, O; Laurikka-Routti, M1
Alvarez, F; Brache, V; Elomaa, K; Fraser, IS; Lacarra, M; Lähteenmäki, P; Mishell, DR; Nash, HA; Weisberg, E1
Jackanicz, T; Kumar, N; Sitruk-Ware, R; Small, M; Sundaram, K; Tsong, YY1
Alvarez, F; Apter, D; Brache, V; Fraser, IS; Gale, J; Massai, R; Mishell, DR; Sivin, I; Tsong, YY; Weisberg, E2
Alvarez, F; Brache, V; Cochon, L; Croxatto, HB; Faundes, A; Forcelledo, ML; Massai, R; Pavez, M; Salvatierra, AM1
Burggraaf, J; de Kam, ML; Kluft, C; Meijer, P; Ménard, J; Rad, M; Sitruk-Ware, RL; Sivin, I1
Burggraaf, J; de Kam, ML; Kluft, C; Menard, J; Rad, M; Sitruk-Ware, RL; Sivin, I; Tokay, BA1
Burggraaf, J; Cohen, AF; de Kam, ML; Kluft, C; Rad, M1
Burggraaf, J; Cohen, AF; de Kam, ML; Kluft, C; Rad, M; Sitruk-Ware, RL1
Cooney, M; Hewett, PC; Hoskin, E; Mensch, BS; Merkatz, RB; Plagianos, M1
Archer, DF; Blithe, D; Conard, J; Creasy, GW; Merkatz, RB; Plagianos, M; Roberts, K; Sitruk-Ware, R; Thomas, MA1
Alami, M; Creasy, G; Han, L; Hoskin, E; Kumar, N; Merkatz, R; Plagianos, M; Roberts, K; Simmons, KB; Variano, B1
Merkatz, RB; Plagianos, M; Stifani, BM; Vieira, CS1
Blithe, DL; Blue, SW; Edelman, AB; Erikson, DW; Fecteau, KM; Jensen, JT1

Reviews

1 review(s) available for st 1435 and ethinyl estradiol

ArticleYear
Nestorone: clinical applications for contraception and HRT.
    Steroids, 2003, Volume: 68, Issue:10-13

    Topics: Animals; Contraception; Contraceptive Agents, Female; Ethinyl Estradiol; Female; Hormone Replacement Therapy; Humans; Models, Chemical; Norprogesterones; Ovulation; Progesterone; Protein Binding; Rats; Time Factors

2003

Trials

11 trial(s) available for st 1435 and ethinyl estradiol

ArticleYear
Evaluation of four different contraceptive vaginal rings: steroid serum levels, luteal activity, bleeding control and lipid profiles.
    Contraception, 1992, Volume: 46, Issue:4

    Topics: Administration, Intravaginal; Adolescent; Adult; Contraceptive Agents, Female; Contraceptive Devices, Female; Estrogens; Ethinyl Estradiol; Evaluation Studies as Topic; Female; Gonadal Steroid Hormones; Humans; Levonorgestrel; Lipoproteins; Menstrual Cycle; Menstruation; Norprogesterones; Progesterone; Radioimmunoassay

1992
Vaginal epithelial surface appearances in women using vaginal rings for contraception.
    Contraception, 2000, Volume: 61, Issue:2

    Topics: Adolescent; Adult; Colposcopy; Contraceptive Agents, Female; Contraceptive Devices, Female; Edema; Epithelium; Erythema; Ethinyl Estradiol; Female; Humans; Norethindrone; Norprogesterones; Progesterone Congeners; Ulcer; Vagina

2000
Serum Nestorone and ethinyl estradiol levels, and ovulation inhibition in women using three different dosage combinations of a Nestorone progestogen-ethinyl estradiol contraceptive vaginal ring on a bleeding-signaled regimen.
    Contraception, 2005, Volume: 72, Issue:1

    Topics: Contraceptive Agents, Female; Contraceptive Devices, Female; Ethinyl Estradiol; Female; Humans; Menstruation; Norprogesterones; Ovarian Follicle; Ovulation Inhibition; Pregnancy; Progesterone

2005
Clinical performance and menstrual bleeding patterns with three dosage combinations of a Nestorone progestogen/ethinyl estradiol contraceptive vaginal ring used on a bleeding-signaled regimen.
    Contraception, 2005, Volume: 72, Issue:1

    Topics: Adult; Contraceptive Agents, Female; Contraceptive Devices, Female; Ethinyl Estradiol; Female; Humans; Menstruation; Norprogesterones; Pregnancy; Uterine Hemorrhage

2005
Feasibility study of Nestorone-ethinylestradiol vaginal contraceptive ring for emergency contraception.
    Contraception, 2006, Volume: 73, Issue:1

    Topics: Administration, Intravaginal; Adult; Contraception, Postcoital; Estradiol; Ethinyl Estradiol; Female; Follicle Stimulating Hormone; Humans; Luteinizing Hormone; Menstrual Cycle; Norprogesterones; Ovarian Follicle; Ovulation; Progesterone; Ultrasonography; Uterine Hemorrhage

2006
Comparative effects of a contraceptive vaginal ring delivering a nonandrogenic progestin and continuous ethinyl estradiol and a combined oral contraceptive containing levonorgestrel on hemostasis variables.
    American journal of obstetrics and gynecology, 2006, Volume: 195, Issue:1

    Topics: Activated Protein C Resistance; Adolescent; Adult; Blood Coagulation Factors; Contraceptive Agents, Female; Contraceptive Devices, Female; Contraceptives, Oral, Combined; Estrogens; Ethinyl Estradiol; Ethinyl Estradiol-Norgestrel Combination; Female; Fibrinolysis; Humans; Immunoradiometric Assay; Norprogesterones; Plasminogen; Protein C; Sex Hormone-Binding Globulin

2006
Comparison of the impact of vaginal and oral administration of combined hormonal contraceptives on hepatic proteins sensitive to estrogen.
    Contraception, 2007, Volume: 75, Issue:6

    Topics: Adolescent; Adult; Blood Proteins; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Contraceptive Agents, Female; Contraceptive Devices, Female; Contraceptives, Oral, Combined; Ethinyl Estradiol; Female; Humans; Levonorgestrel; Menstrual Cycle; Norprogesterones; Sex Hormone-Binding Globulin; Triglycerides

2007
Increased impact of a contraceptive vaginal ring with ethinyl estradiol and nestorone on C-reactive protein.
    Steroids, 2012, Volume: 77, Issue:13

    Topics: Adolescent; Adult; C-Reactive Protein; Contraceptive Devices, Female; Ethinyl Estradiol; Female; Humans; Norprogesterones; Young Adult

2012
Impact on hepatic estrogen-sensitive proteins by a 1-year contraceptive vaginal ring delivering Nestorone® and ethinyl estradiol.
    Contraception, 2016, Volume: 93, Issue:1

    Topics: Adult; Contraceptive Agents, Female; Contraceptive Devices, Female; Contraceptives, Oral, Combined; Contraceptives, Oral, Hormonal; Estrogens; Ethinyl Estradiol; Factor VIII; Female; Fibrinogen; Humans; Norprogesterones; Protein S; Sex Hormone-Binding Globulin

2016
Effects of concurrent vaginal miconazole treatment on the absorption and exposure of Nestorone® (segesterone acetate) and ethinyl estradiol delivered from a contraceptive vaginal ring: a randomized, crossover drug-drug interaction study.
    Contraception, 2018, Volume: 97, Issue:3

    Topics: Administration, Intravaginal; Adolescent; Adult; Antifungal Agents; Area Under Curve; Candidiasis, Vulvovaginal; Contraceptive Agents, Female; Contraceptive Devices, Female; Cross-Over Studies; Drug Interactions; Drug Therapy, Combination; Ethinyl Estradiol; Female; Humans; Miconazole; Norprogesterones; Vaginal Absorption; Young Adult

2018
Factors associated with nonadherence to instructions for using the Nestorone®/ethinyl estradiol contraceptive vaginal ring.
    Contraception, 2018, Volume: 97, Issue:5

    Topics: Adult; Contraceptive Agents, Female; Contraceptive Devices, Female; Ethinyl Estradiol; Factor Analysis, Statistical; Female; Humans; Internationality; Logistic Models; Multivariate Analysis; Norprogesterones; Patient Compliance; Young Adult

2018

Other Studies

4 other study(ies) available for st 1435 and ethinyl estradiol

ArticleYear
A contraceptive vaginal ring releasing ethinyl estradiol and the progestin ST-1435: bleeding control, serum steroid concentrations, serum lipids and serum chemistry.
    Contraception, 1990, Volume: 42, Issue:1

    Topics: Adult; Cholesterol, HDL; Cholesterol, LDL; Contraceptive Devices, Female; Estradiol; Ethinyl Estradiol; Female; Humans; Liver; Menstruation; Minerals; Norpregnenes; Norprogesterones; Progesterone; Triglycerides

1990
Discriminant analysis of the metabolic effects of a new combined contraceptive vaginal ring containing Nestorone/EE vs. a second-generation oral contraceptive containing levonorgestrel/EE.
    Contraception, 2012, Volume: 86, Issue:3

    Topics: Angiotensinogen; Blood Coagulation Factors; Blood Pressure; C-Reactive Protein; Cholesterol, HDL; Cholesterol, LDL; Contraceptive Devices, Female; Contraceptives, Oral, Combined; Discriminant Analysis; Drug Combinations; Ethinyl Estradiol; Female; Humans; Levonorgestrel; Norprogesterones; Risk; Sex Hormone-Binding Globulin; Thrombosis; Triglycerides

2012
Acceptability of the Nestorone®/ethinyl estradiol contraceptive vaginal ring: development of a model; implications for introduction.
    Contraception, 2014, Volume: 90, Issue:5

    Topics: Adolescent; Adult; Contraceptive Agents, Female; Contraceptive Devices, Female; Ethinyl Estradiol; Factor Analysis, Statistical; Female; Humans; Models, Theoretical; Norprogesterones; Patient Acceptance of Health Care; Young Adult

2014
Simultaneous assay of segesterone acetate (Nestorone®), estradiol, progesterone, and estrone in human serum by LC-MS/MS.
    Contraception, 2020, Volume: 102, Issue:5

    Topics: Chromatography, Liquid; Drug Combinations; Estradiol; Estrone; Ethinyl Estradiol; Female; Humans; Norprogesterones; Pregnenediones; Progesterone; Tandem Mass Spectrometry

2020