sr141716 has been researched along with sr 144528 in 137 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (5.11) | 18.2507 |
| 2000's | 100 (72.99) | 29.6817 |
| 2010's | 30 (21.90) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Allarà, M; Brizzi, A; Corelli, F; Di Marzo, V; Lamponi, S; Ligresti, A; Mor, M; Mugnaini, C; Silva, C; Vacondio, F | 1 |
| Bartolini, M; Decker, M; Dolles, D; Falkeis, C; Gmeiner, P; Gunesch, S; Hoffmann, M; Hübner, H; Maitra, R; Marinelli, O; Maurice, T; Monti, B; Nabissi, M; Naldi, M; Petralla, S; Poeta, E; Scheiner, M; Vieth, M | 1 |
| Bouaboula, M; Casellas, P; Derocq, JM; Marchand, J; Rinaldi-Carmona, M; Ségui, M | 1 |
| Fields, HL; Meng, ID | 1 |
| Bord, A; Bouaboula, M; Carayon, P; Casellas, P; Defrance, T; Derocq, JM; Dussossoy, D; Fur, GL; Galiègue, S; Jbilo, O; Marchand, J; Mondière, P; Pénarier, G | 1 |
| Brockie, HC; Fernando, SR; Pertwee, RG; Razdan, RK; Ross, RA; Saha, B | 1 |
| Barth, F; Bouaboula, M; Calandra, B; Casellas, P; Ferrara, P; Rinaldi-Carmona, M; Shire, D | 1 |
| Breuer, A; Fride, E; Goldenberg, D; Hanus, L; Horowitz, M; Mechoulam, R; Pertwee, RG; Ross, RA; Shiloah, S; Tchilibon, S | 1 |
| Kishimoto, S; Kodaka, T; Kondo, S; Miyashita, T; Nakane, S; Sugiura, T; Suhara, Y; Takayama, H; Waku, K | 1 |
| Adami, M; Coppelli, G; Coruzzi, G; Frati, P; Soldani, G | 1 |
| Bonner, TI; Goparaju, SK; Járai, Z; Kunos, G; Razdan, RK; Sugiura, T; Wagner, JA; Wang, L; Zimmer, A; Zimmer, AM | 1 |
| Capasso, F; Izzo, AA; Mascolo, N; Tonini, M | 1 |
| Baker, D; Brown, P; Croxford, JL; Huffman, JW; Layward, L; Pertwee, RG; Pryce, G | 1 |
| Angus, JA; Lay, L; Wright, CE | 1 |
| Bouaboula, M; Casellas, P; Dornand, J; Gross, A; Liautard, JP; Marchant, J; Ouahrani-Bettache, S; Terraza, A | 1 |
| Denhardt, G; Smith, SR; Terminelli, C | 2 |
| Borrelli, F; Capasso, F; Capasso, R; Izzo, AA; Mascolo, N; Pinto, L | 1 |
| Ambrosino, G; Beaulieu1, P; Bisogno1, T; Di Marzo, V; Farquhar-Smith, WP; Punwar, S; Rice, AS | 1 |
| Brockie, HC; Pertwee, RG; Ross, RA | 1 |
| Massi, P; Panerai, AE; Parolaro, D; Sacerdote, P | 1 |
| Bari, M; Del Principe, D; Finazzi-Agrò, A; Giuliani, E; MacCarrone, M; Menichelli, A | 1 |
| Lagneux, C; Lamontagne, D | 1 |
| Capasso, F; Capasso, R; D'Angelo, V; De Pasquale, R; Germanò, MP; Izzo, AA; Mascolo, N; Mondello, MR; Pergolizzi, S | 1 |
| Brunk, LK; Selley, DE; Sim-Selley, LJ | 1 |
| Kendall, DA; Ralevic, V | 1 |
| Bernatskaya, NA; Graier, VF; Mekhoulam, R; Stefano, JB; Tam, SW; Ugdyzhekova, DS | 1 |
| Corbacho, C; de Ceballos, ML; Galve-Roperh, I; Gomez del Pulgar, T; Guzmán, M; Huffman, JW; Ramón y Cajal, S; Rueda, D; Sánchez, C; Velasco, G | 1 |
| Erbelding, D; Kilbinger, H; Mang, CF | 1 |
| Rice, AS | 1 |
| Bardotti, M; Parolaro, D; Poli, G; Ponti, W; Rubino, T | 1 |
| Capasso, F; Capasso, R; Di Marzo, V; Fezza, F; Izzo, AA; Mascolo, N; Pinto, A | 1 |
| Guaza, C; Molina-Holgado, E; Molina-Holgado, F; Rothwell, NJ | 1 |
| Baker, D; Bifulco, M; Bisogno, T; Bridges, D; Brooks, JW; Brown, P; Di Marzo, V; Hankey, DJ; Jaggar, SI; Ledent, C; Pryce, G; Rice, AS | 1 |
| Advenier, C; Berdyshev, EV; Boichot, E; Germain, N; Lagente, V | 1 |
| Farquhar-Smith, WP; Jaggar, SI; Rice, AS | 1 |
| Lombard, C; Martin, BR; McKallip, RJ; Nagarkatti, M; Nagarkatti, PS | 1 |
| Bernatskaia, NA; Krylatov, AV; Maslov, LN; Mechoulam, R; Pertwee, RG; Sal'nikova, OM; Sharaevskiĭ, MA; Stefano, GB | 1 |
| Cao, YJ; Duan, EK; Liu, WM | 1 |
| Arnaud, C; Demenge, P; Godin-Ribuot, D; Joyeux, M; Lamontagne, D; Ribuot, C | 1 |
| Egan, RW; Hey, JA; Jia, Y; McLeod, RL; Parra, LE; Wang, X | 1 |
| Ihenetu, K; Molleman, A; Parsons, ME; Whelan, CJ | 1 |
| Carbone, JM; Crawford, RB; Kaminski, NE; Ouyang, Y; Rummel, AM; Trosko, JE; Upham, BL | 1 |
| Bouchard, JF; Lamontagne, D; Lépicier, P | 1 |
| Hohmann, AG; Nackley, AG; Suplita, RL | 1 |
| Ihenetu, K; Molleman, A; Parsons, M; Whelan, C | 1 |
| Hiley, CR; Ho, WS | 1 |
| Croft, DL; Hamamoto, DT; Kehl, LJ; Norsted, BD; Simone, DA; Wacnik, PW; Wilcox, GL | 1 |
| Hohmann, AG; Makriyannis, A; Nackley, AG | 1 |
| Bissonnette, CJ; Klegeris, A; McGeer, PL | 1 |
| Bouchard, JF; Lagneux, C; Lamontagne, D; Lépicier, P | 1 |
| Gibson, RM; Guaza, C; Molina-Holgado, E; Molina-Holgado, F; Moore, JD; Pinteaux, E; Rothwell, NJ | 1 |
| Bölcskei, K; Helyes, Z; Németh, J; Pintér, E; Szolcsányi, J; Thán, M | 1 |
| Barnes, PJ; Belvisi, MG; Birrell, MA; Crispino, N; Hele, DJ; Patel, HJ; Venkatesan, P; Yacoub, MH | 1 |
| Chou, J; Friedman, H; Klein, TW; Larsen, K; Lu, L; Newton, C; Nong, L; Perkins, I | 1 |
| Broderick, VM; Dennedy, MC; Friel, AM; Houlihan, DD; Morrison, JJ; Smith, T | 1 |
| Kaminski, NE; Rao, GK; Zhang, W | 1 |
| Angus, JA; Scott, DA; Wright, CE | 1 |
| Godlewski, G; Malinowska, B; Schlicker, E | 1 |
| Duncan, M; Kendall, DA; Ralevic, V | 1 |
| Friedman, H; Klein, TW; Lu, T; Nazian, SJ; Newton, CA; Perkins, I | 1 |
| Abe, T; Arisaka, O; Morimoto, H; Yamada, Y; Yoshihara, S | 1 |
| Colleoni, M; Costa, B; Franke, C; Giagnoni, G; Trovato, AE | 1 |
| Hohmann, AG; Makriyannis, A; Nackley, AG; Zvonok, AM | 1 |
| Cabral, GA; Hu, S; Lokensgard, JR; Min, X; Peterson, PK; Sheng, WS | 1 |
| Bátkai, S; Bukoski, RD; Harvey-White, J; Kunos, G; Liu, J; Mackie, K; Offertáler, L; Osei-Hyiaman, D; Pacher, P; Radaeva, S; Rudd, MA | 1 |
| Chapman, V; Elmes, SJ; Jhaveri, MD; Kendall, DA; Smart, D | 1 |
| Bembry, J; Chen, Y; Golech, SA; Lenz, F; McCarron, RM; Mechoulam, R; Shohami, E; Spatz, M | 1 |
| Bariselli, F; Colombo, A; Martucci, C; Massi, P; Panerai, AE; Parolaro, D; Sacerdote, P; Vaccani, A | 1 |
| Freiman, I; Szabo, B | 1 |
| Breuer, A; Fride, E; Hanus, L; Ponde, D | 1 |
| Chapman, V; Kelly, S; Kendall, DA; Millns, PJ; O'Shaughnessey, CT; Sagar, DR | 1 |
| Abe, T; Arisaka, O; Morimoto, H; Ohori, M; Yamada, Y; Yoshihara, S | 2 |
| Krylatov, AV; Lasukova, OV; Maslov, LN; Pertwee, RG | 1 |
| Järbe, TU; Liu, Q; Makriyannis, A | 1 |
| Cowan, A; Ding, Z; Rawls, SM | 1 |
| Darmani, NA | 1 |
| Auchampach, JA; Carrier, EJ; Hillard, CJ | 1 |
| Cichewicz, DL; Haller, VL; Welch, SP | 1 |
| Liu, C; Walker, JM | 1 |
| Bueno, L; Fioramonti, J; Sanson, M | 1 |
| Diamond, M; Finn, DP; Kelly, JP; Roche, M | 1 |
| Adler, MW; Benamar, K; Eisenstein, TK; Geller, EB; Meissler, JJ; Tallarida, RJ; Yondorf, M | 1 |
| Baillie, GL; Pertwee, RG; Phillips, AM; Razdan, RK; Ross, RA; Thomas, A | 1 |
| Arévalo-Martín, A; García-Ovejero, D; Gómez-Torres, O; Molina-Holgado, E; Molina-Holgado, F; Moore, JD; Rubio-Araiz, A; Williams, RJ | 1 |
| Arai, S; Oka, S; Sugiura, T; Tokumura, A; Waku, K | 1 |
| Howlett, AC; McCollum, L; Mukhopadhyay, S | 1 |
| Crowford, D; Hanus, LO; Ivanchuk, II; Krylatov, AV; Lasukova, OV; Maslov, LN; Pertwee, R | 1 |
| Buettner, R; Cravatt, B; Date, R; Di Marzo, V; Gaffal, E; Karsak, M; Mechoulam, R; Petrosino, S; Rehnelt, J; Schlicker, E; Starowicz, K; Steuder, R; Tüting, T; Wang-Eckhardt, L; Werner, S; Zimmer, A | 1 |
| Blackbeard, J; Hasnie, F; Lambert, DM; Pheby, T; Rice, AS; Segerdahl, AR; Vandevoorde, S; Wallace, VC | 1 |
| Dekkers, BG; Dröge, MJ; Elzinga, CR; Gkoumassi, E; Meurs, H; Nelemans, SA; Schmidt, M; Zaagsma, J | 1 |
| Hohmann, AG; Makriyannis, A; Rahn, EJ | 1 |
| Cox, ML; Haller, VL; Welch, SP | 1 |
| Advenier, C; Chen, HZ; Cui, YY; D'Agostino, B; Finance, O; Marrocco, G; Naline, E; Rinaldi-Carmona, M; Risse, PA; Rossi, F; Zhang, Y | 1 |
| Dinc, M; Oz, M; Shippenberg, TS; Yang, KH | 1 |
| Bettoni, I; Colleoni, M; Comelli, F; Costa, B; Giagnoni, G | 1 |
| Herradón, E; López-Miranda, V; Martín, MI | 1 |
| Allen, RC; Castillo, IG; Hosseini, A; Lattanzio, FA; Lichtman, AH; Oltmanns, MH; Samudre, SS; Williams, PB | 1 |
| Agudelo, M; Friedman, H; Klein, TW; Newton, C; Nong, L; Sherwood, T; Widen, R | 1 |
| Buckley, NE; Cabral, GA; Marciano-Cabral, F; Martin, BR; Raborn, ES | 1 |
| Järbe, TU; Li, C; Makriyannis, A; Vadivel, SK | 1 |
| Adler, MW; Benamar, K; Geller, EB | 1 |
| Bernardini, D; Colavito, D; D'Arrigo, A; Dalle Carbonare, M; Dam, M; Del Giudice, E; Fabris, M; Leon, A; Stecca, A | 1 |
| Njie, YF; Qiao, Z; Song, ZH; Wang, W; Xiao, Z | 1 |
| He, F; Njie, YF; Qiao, Z; Song, ZH | 1 |
| Chu, KL; Dart, MJ; McGaraughty, S; Meyer, MD; Yao, BB | 1 |
| Burgos, E; Goicoechea, C; Martín, MI; Pascual, D | 1 |
| Booker, L; Lichtman, AH; Mahadevan, A; Naidu, PS; Razdan, RK | 1 |
| Bhat, M; Bowen, WD; Cheng, J; Liu, Q | 1 |
| Battistini, L; Bernardi, G; Borsellino, G; Catanzaro, G; Cencioni, MT; Chiurchiù, V; Maccarrone, M | 1 |
| Abe, T; Fukuda, H; Yoshihara, S | 1 |
| DeLong, GT; Lichtman, AH; Poklis, A; Wolf, CE | 1 |
| Avigliano, L; Baldassarri, S; Bertoni, A; Catani, MV; Catanzaro, G; Gasperi, V; Maccarrone, M; Sinigaglia, F | 1 |
| Barbonetti, A; Fortunato, D; Francavilla, F; Francavilla, S; Maccarrone, M; Vassallo, MR | 1 |
| Hegde, VL; Nagarkatti, M; Nagarkatti, PS | 1 |
| Chen, C; Chen, X; Zhang, J | 1 |
| Hohmann, AG; Makriyannis, A; Rahn, EJ; Thakur, GA; Wood, JA; Zvonok, AM | 1 |
| Almeida, MC; Balaskó, M; Dogan, MD; Eales, J; Gavva, NR; Molchanova, AY; Oliveira, DL; Patel, S; Pétervári, E; Romanovsky, AA; Steiner, AA; Székely, M; Wanner, SP | 1 |
| Altun, A; Bagcivan, I; Durmus, N; Kaya, T; Sarac, B; Sencan, M; Turan, M | 1 |
| Benigni, F; Bettiga, A; Colciago, G; Gandaglia, G; Gratzke, C; Hedlund, P; Montorsi, F; Rigatti, P; Stief, C; Strittmatter, F | 1 |
| Gadthula, S; Kottani, R; Mahadeven, A; Selley, DE; Wang, P; Wiley, JL | 1 |
| Craft, RM; Laggart, JD; Tsutsui, KT; Wakley, AA | 1 |
| Kumar, A; Kumar, P; Qiao, Z; Song, ZH | 1 |
| Di Marzo, V; Imming, P; Lichtman, AH; Radanova, L; Schlosburg, JE | 1 |
| Aguiar, DC; Campos, AC; Díaz-Alonso, J; Fogaça, MV; Galve-Roperh, I; Guimarães, FS; Guzmán, M; Moreira, FA; Ortega, Z; Ortega-Gutiérrez, S; Palazuelos, J; Vázquez-Villa, H | 1 |
| Craft, RM; Davis, SM; Kandasamy, R | 1 |
| Andrade, SP; Barcelos, LS; Coelho, AM; Ferreira, MA; Gomes, AK; Guabiraba, R; Lopes, GA; Russo, RC; Teixeira, MM | 1 |
| Aizawa, N; Füllhase, C; Hedlund, P; Homma, Y; Igawa, Y; Ito, H | 1 |
| Balvers, MG; Dwarkasing, J; Lute, C; Meijerink, J; Plastina, P; Poland, M; van Norren, K; Witkamp, RF | 1 |
| Feng, R; Milcarek, CA; Xie, XQ | 1 |
| Vizzard, MA | 1 |
| Castiglione, F; Füllhase, C; Giese, A; Gratzke, C; Hedlund, P; La Croce, G; Montorsi, F; Schmidt, M; Schreiber, A; Stief, C | 1 |
| Craft, RM; Greene, NZ; Wakley, AA | 1 |
| Asahi, H; Inoue, SI; Kobayashi, F; Kunigo, K; Niikura, M; Sendo, F; Suzuki, Y | 1 |
| Cheng, J; Jiang, C; Wu, J; Yu, J; Zhou, X; Zong, Y | 1 |
| Ashba, AM; Bezuglov, VV; Bobrov, MY; Fedorova-Gogolina, IA; Gretskaya, NM; Melkumyan, AG; Pavlovich, SV; Yushina, MN | 1 |
2 review(s) available for sr141716 and sr 144528
| Article | Year |
|---|---|
Cannabinoid receptor interactions with the antagonists SR 141716A and SR 144528.
Topics: Amino Acid Sequence; Animals; Binding Sites; Camphanes; Cannabinoids; Humans; Molecular Sequence Data; Piperidines; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant | 1999 |
Cannabinoids and pain.
Topics: Amides; Amidohydrolases; Analgesics; Animals; Arachidonic Acids; Benzoxazines; Brain; Camphanes; Cannabinoid Receptor Modulators; Cannabinoids; Cell Membrane; Clinical Trials as Topic; Disease Models, Animal; Drug Design; Drug Interactions; Endocannabinoids; Enzyme Inhibitors; Ethanolamines; Glycerides; Humans; Injections, Spinal; Molecular Structure; Morpholines; Naphthalenes; Pain; Palmitates; Palmitic Acids; Piperidines; Plant Extracts; Polyunsaturated Alkamides; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Spinal Cord | 2001 |
135 other study(ies) available for sr141716 and sr 144528
| Article | Year |
|---|---|
Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 7. Synthesis and Pharmacological Evaluation of 4-Quinolone-3-carboxamides and 4-Hydroxy-2-quinolone-3-carboxamides as High Affinity Cannabinoid Receptor 2 (CB2R) Ligands with Improved Aqueous Solu
Topics: Animals; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Ligands; Mice; Molecular Structure; NIH 3T3 Cells; Quinolones; Receptor, Cannabinoid, CB2; Solubility; Structure-Activity Relationship; Water | 2016 |
Dual-Acting Cholinesterase-Human Cannabinoid Receptor 2 Ligands Show Pronounced Neuroprotection in Vitro and Overadditive and Disease-Modifying Neuroprotective Effects in Vivo.
Topics: Animals; Cholinesterases; Humans; Ligands; Mice; Neuroprotective Agents; Receptor, Cannabinoid, CB2 | 2019 |
The endogenous cannabinoid anandamide is a lipid messenger activating cell growth via a cannabinoid receptor-independent pathway in hematopoietic cell lines.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium-Calmodulin-Dependent Protein Kinases; Camphanes; Cannabinoids; Cell Division; CHO Cells; Cricetinae; Cyclohexanols; Endocannabinoids; Enzyme Activation; Gene Expression Regulation; Mice; Pertussis Toxin; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; RNA, Messenger; Signal Transduction; Transfection; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1998 |
Watching the pot boil.
Topics: Amides; Analgesics; Animals; Arachidonic Acids; Camphanes; Cannabinoids; Endocannabinoids; Ethanolamines; Mice; Palmitic Acids; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant | 1998 |
Modulation and functional involvement of CB2 peripheral cannabinoid receptors during B-cell differentiation.
Topics: Animals; B-Lymphocyte Subsets; Camphanes; CD40 Antigens; Cell Differentiation; CHO Cells; Cricetinae; Cricetulus; Cyclohexanols; Germinal Center; Humans; Microscopy, Confocal; Palatine Tonsil; Peptide Fragments; Piperidines; Pyrazoles; Rabbits; Receptors, Cannabinoid; Receptors, Drug; Recombinant Fusion Proteins; Rimonabant; Transfection | 1998 |
Comparison of cannabinoid binding sites in guinea-pig forebrain and small intestine.
Topics: Analgesics; Animals; Benzoxazines; Binding Sites; Binding, Competitive; Camphanes; Cyclohexanols; Dronabinol; Guinea Pigs; Intestine, Small; Kinetics; Male; Morpholines; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Naphthalenes; Neuromuscular Junction; Piperidines; Prosencephalon; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Tritium | 1998 |
HU-308: a specific agonist for CB(2), a peripheral cannabinoid receptor.
Topics: Analgesics; Animals; Arachidonic Acid; Blood Pressure; Camphanes; Cannabinoids; Cyclic AMP; Female; Mice; Piperidines; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Structure-Activity Relationship | 1999 |
Evidence that 2-arachidonoylglycerol but not N-palmitoylethanolamine or anandamide is the physiological ligand for the cannabinoid CB2 receptor. Comparison of the agonistic activities of various cannabinoid receptor ligands in HL-60 cells.
Topics: Amides; Arachidonic Acids; Calcium Signaling; Camphanes; Cannabinoids; Cyclohexanols; Cyclooxygenase Inhibitors; Drug Interactions; Endocannabinoids; Ethanolamines; Glycerides; HL-60 Cells; Humans; Ligands; Lipoxygenase Inhibitors; Molecular Mimicry; Palmitic Acids; Pertussis Toxin; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; RNA, Messenger; Structure-Activity Relationship; Virulence Factors, Bordetella | 2000 |
Inhibitory effect of the cannabinoid receptor agonist WIN 55,212-2 on pentagastrin-induced gastric acid secretion in the anaesthetized rat.
Topics: Anesthesia; Animals; Benzoxazines; Camphanes; Cannabinoids; Gastric Acid; Gastric Mucosa; Indoles; Isomerism; Male; Morpholines; Naphthalenes; Pentagastrin; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Drug; Rimonabant | 1999 |
Cardiovascular effects of 2-arachidonoyl glycerol in anesthetized mice.
Topics: Anesthesia; Animals; Arachidonic Acids; Blood Pressure; Camphanes; Cardiovascular Agents; Cardiovascular Diseases; Dose-Response Relationship, Drug; Endocannabinoids; Female; Glycerides; Heart Rate; Hypotension; Indomethacin; Ligands; Male; Mice; Mice, Inbred ICR; Mice, Knockout; Piperidines; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Tachycardia | 2000 |
Modulation of peristalsis by cannabinoid CB(1) ligands in the isolated guinea-pig ileum.
Topics: Animals; Benzoxazines; Camphanes; Cannabinoids; Compliance; Cyclohexanols; Guinea Pigs; Ileum; In Vitro Techniques; Ligands; Male; Morpholines; Muscle Contraction; Naphthalenes; Peristalsis; Piperidines; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant | 2000 |
Cannabinoids control spasticity and tremor in a multiple sclerosis model.
Topics: Animals; Camphanes; Cannabinoids; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Mice; Multiple Sclerosis; Piperidines; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Spasm; Tremor | 2000 |
Pharmacological characterisation of cannabinoid CB(1) receptors in the rat and mouse.
Topics: Animals; Arachidonic Acids; Camphanes; Cannabinoids; Cyclohexanols; Dronabinol; Endocannabinoids; Heart Atria; In Vitro Techniques; Male; Mesenteric Artery, Inferior; Mice; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Sympathetic Nervous System; Synaptic Transmission; Vas Deferens; Vascular Resistance | 2000 |
A beneficial aspect of a CB1 cannabinoid receptor antagonist: SR141716A is a potent inhibitor of macrophage infection by the intracellular pathogen Brucella suis.
Topics: Animals; Anti-Bacterial Agents; Antigens, CD; Benzoxazines; Brucella; Calcitriol; Camphanes; Cell Differentiation; Cell Line; Colforsin; Cyclic AMP; Cyclohexanols; Dose-Response Relationship, Drug; Humans; Intercellular Adhesion Molecule-1; Macrophage Activation; Macrophages; Mice; Monocytes; Morpholines; Naphthalenes; Phagocytosis; Piperidines; Pyrazoles; Reactive Oxygen Species; Receptors, Cannabinoid; Receptors, Drug; Rimonabant | 2000 |
Effects of cannabinoid receptor agonist and antagonist ligands on production of inflammatory cytokines and anti-inflammatory interleukin-10 in endotoxemic mice.
Topics: Animals; Benzoxazines; Camphanes; Cannabinoids; Cytokines; Dronabinol; Endotoxemia; Endotoxins; Interleukin-10; Interleukin-12; Interleukin-2; Ligands; Lipopolysaccharides; Male; Mice; Morpholines; Naphthalenes; Piperidines; Propionibacterium acnes; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Tumor Necrosis Factor-alpha | 2000 |
Central and peripheral cannabinoid modulation of gastrointestinal transit in physiological states or during the diarrhoea induced by croton oil.
Topics: Animals; Antidiarrheals; Benzoxazines; Camphanes; Cannabinoids; Croton Oil; Diarrhea; Gastrointestinal Transit; Male; Mice; Mice, Inbred ICR; Morpholines; Naphthalenes; Piperidines; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant | 2000 |
Role of the endogenous cannabinoid system in the formalin test of persistent pain in the rat.
Topics: Animals; Camphanes; Cannabinoid Receptor Modulators; Formaldehyde; Hyperalgesia; Male; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Drug; Rimonabant | 2000 |
Inhibition of nitric oxide production in RAW264.7 macrophages by cannabinoids and palmitoylethanolamide.
Topics: Amides; Animals; Benzoxazines; Camphanes; Cannabinoids; Cell Line; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Dose-Response Relationship, Drug; Endocannabinoids; Ethanolamines; Humans; Lipopolysaccharides; Macrophages; Morpholines; Naphthalenes; Nitric Oxide; Palmitic Acids; Pertussis Toxin; Piperidines; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Stereoisomerism; Time Factors; Virulence Factors, Bordetella | 2000 |
In vivo and in vitro treatment with the synthetic cannabinoid CP55, 940 decreases the in vitro migration of macrophages in the rat: involvement of both CB1 and CB2 receptors.
Topics: Animals; Camphanes; Cannabinoids; Cell Movement; Cells, Cultured; Cyclohexanols; Dose-Response Relationship, Drug; Immunosuppressive Agents; In Vitro Techniques; Macrophages, Peritoneal; Male; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Drug; Rimonabant | 2000 |
Human platelets bind and degrade 2-arachidonoylglycerol, which activates these cells through a cannabinoid receptor.
Topics: Adenosine Diphosphate; Amidohydrolases; Arachidonic Acids; Aspirin; Biological Transport; Blood Platelets; Calcium Channel Blockers; Camphanes; Cannabinoid Receptor Modulators; Collagen; Cyclic AMP; Endocannabinoids; Glycerides; Humans; Hydrolysis; Inositol 1,4,5-Trisphosphate; Kinetics; Piperidines; Platelet Activation; Polyunsaturated Alkamides; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Serotonin; Time Factors | 2001 |
Involvement of cannabinoids in the cardioprotection induced by lipopolysaccharide.
Topics: Animals; Camphanes; Cannabinoid Receptor Modulators; Heart; Lipopolysaccharides; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Nitric Oxide; Piperidines; Protective Agents; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Drug; Rimonabant | 2001 |
Cannabinoid CB1-mediated inhibition of stress-induced gastric ulcers in rats.
Topics: Animals; Benzoxazines; Camphanes; Male; Morpholines; Naphthalenes; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Stomach Ulcer; Stress, Physiological | 2001 |
Inhibitory effects of SR141716A on G-protein activation in rat brain.
Topics: Animals; Benzoxazines; Brain; Calcium Channel Blockers; Camphanes; Dose-Response Relationship, Drug; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Male; Morpholines; Naphthalenes; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Sodium Chloride | 2001 |
Cannabinoid inhibition of capsaicin-sensitive sensory neurotransmission in the rat mesenteric arterial bed.
Topics: Adenosine Diphosphate; Animals; Benzofurans; Calcitonin Gene-Related Peptide; Camphanes; Cannabinoids; Capsaicin; Dose-Response Relationship, Drug; Dronabinol; Electric Stimulation; Electrophysiology; Male; Mesenteric Arteries; Neurons, Afferent; Nitroprusside; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Synaptic Transmission; Time Factors; Vasodilation; Vasodilator Agents | 2001 |
Endogenous cannabinoid anandamide increases heart resistance to arrhythmogenic effects of epinephrine: role of CB(1) and CB(2) receptors.
Topics: Animals; Arachidonic Acids; Arrhythmias, Cardiac; Camphanes; Electrocardiography; Endocannabinoids; Epinephrine; Heart; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Drug; Rimonabant | 2001 |
Inhibition of glioma growth in vivo by selective activation of the CB(2) cannabinoid receptor.
Topics: Animals; Antineoplastic Agents; Apoptosis; Astrocytoma; Benzoxazines; Brain Neoplasms; Camphanes; Cannabinoids; Cell Division; Ceramides; Glioma; Growth Inhibitors; Humans; Mice; Morpholines; Naphthalenes; Piperidines; Pyrazoles; Rats; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Signal Transduction; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2001 |
Differential effects of anandamide on acetylcholine release in the guinea-pig ileum mediated via vanilloid and non-CB1 cannabinoid receptors.
Topics: Acetylcholine; Animals; Arachidonic Acids; Camphanes; Capsaicin; Cyclohexanols; Dose-Response Relationship, Drug; Electric Stimulation; Endocannabinoids; Guinea Pigs; Ileum; In Vitro Techniques; Male; Methacholine Chloride; Muscle Contraction; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant | 2001 |
Cannabinoids inhibit nitric oxide production in bone marrow derived feline macrophages.
Topics: Animals; Bone Marrow Cells; Camphanes; Cannabinoids; Cats; Cyclohexanols; Disease Models, Animal; Feline Acquired Immunodeficiency Syndrome; Histocytochemistry; Immunosuppressive Agents; Macrophages; Nitric Oxide; Phagocytosis; Piperidines; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant | 2001 |
Modulation of cytokine responses in Corynebacterium parvum-primed endotoxemic mice by centrally administered cannabinoid ligands.
Topics: Animals; Benzoxazines; Camphanes; Cannabinoids; Cytokines; Dose-Response Relationship, Drug; Dronabinol; Endotoxemia; Endotoxins; Injections, Intraperitoneal; Injections, Intravenous; Injections, Intraventricular; Interleukin-10; Interleukin-12; Ligands; Male; Mice; Mice, Knockout; Morpholines; Naphthalenes; Piperidines; Propionibacterium acnes; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Survival Rate; Tumor Necrosis Factor-alpha; Virulence Factors, Bordetella | 2001 |
Inhibitory effect of palmitoylethanolamide on gastrointestinal motility in mice.
Topics: Adrenergic alpha-Antagonists; Amides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Camphanes; Croton Oil; Dose-Response Relationship, Drug; Endocannabinoids; Enzyme Inhibitors; Ethanolamines; Gastrointestinal Motility; Gastrointestinal Transit; Hexamethonium; Inflammation; Intestine, Small; Male; Mice; Mice, Inbred ICR; Naloxone; NG-Nitroarginine Methyl Ester; Nicotinic Antagonists; Nitric Oxide Synthase; Palmitic Acids; Phenylmethylsulfonyl Fluoride; Piperidines; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Yohimbine | 2001 |
Role of CB1 and CB2 receptors in the inhibitory effects of cannabinoids on lipopolysaccharide-induced nitric oxide release in astrocyte cultures.
Topics: Analgesics; Animals; Arachidonic Acids; Astrocytes; Calcium Channel Blockers; Camphanes; Cannabinoids; Cells, Cultured; Cyclohexanols; Dronabinol; Endocannabinoids; Gene Expression; Lipopolysaccharides; Mice; Mice, Inbred Strains; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant | 2002 |
Arvanil-induced inhibition of spasticity and persistent pain: evidence for therapeutic sites of action different from the vanilloid VR1 receptor and cannabinoid CB(1)/CB(2) receptors.
Topics: Animals; Arachidonic Acids; Benzoxazines; Camphanes; Cannabinoid Receptor Modulators; Capsaicin; Disease Models, Animal; Dose-Response Relationship, Drug; Genotype; Mice; Mice, Inbred Strains; Mice, Knockout; Morpholines; Multiple Sclerosis; Muscle Spasticity; Naphthalenes; Pain; Pain Measurement; Piperidines; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant | 2002 |
Effect of the cannabinoid receptor ligand, WIN 55,212-2, on superoxide anion and TNF-alpha production by human mononuclear cells.
Topics: Benzoxazines; Camphanes; Cannabinoids; Down-Regulation; Humans; Leukocytes, Mononuclear; Ligands; Lipopolysaccharides; Morpholines; Naphthalenes; Piperidines; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Superoxides; Tumor Necrosis Factor-alpha; Up-Regulation | 2002 |
Attenuation of nerve growth factor-induced visceral hyperalgesia via cannabinoid CB(1) and CB(2)-like receptors.
Topics: Amides; Animals; Arachidonic Acids; Camphanes; Cannabinoid Receptor Modulators; Cannabinoids; Endocannabinoids; Ethanolamines; Female; Hyperalgesia; Nerve Growth Factor; Palmitic Acids; Piperidines; Polyunsaturated Alkamides; Proto-Oncogene Proteins c-fos; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Drug; Reflex, Abnormal; Rimonabant; Spinal Cord; Urinary Bladder; Visceral Afferents | 2002 |
Delta(9)-tetrahydrocannabinol-induced apoptosis in the thymus and spleen as a mechanism of immunosuppression in vitro and in vivo.
Topics: Animals; Apoptosis; Camphanes; Concanavalin A; Dose-Response Relationship, Drug; Dronabinol; Female; Immune Tolerance; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Piperidines; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Spleen; Thymus Gland | 2002 |
[Increase of the heart arrhythmogenic resistance and decrease of the myocardial necrosis zone during activation of cannabinoid receptors].
Topics: Aconitine; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Arterial Occlusive Diseases; Camphanes; Cannabinoids; Coronary Artery Disease; Dronabinol; Epinephrine; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Drug; Rimonabant | 2002 |
Effects of anandamide on embryo implantation in the mouse.
Topics: Animals; Arachidonic Acids; Blastocyst; Camphanes; Dose-Response Relationship, Drug; Embryo Implantation; Embryonic and Fetal Development; Endocannabinoids; Epithelial Cells; Female; Mice; Piperidines; Polyunsaturated Alkamides; Pregnancy; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Uterus | 2002 |
Endocannabinoids are implicated in the infarct size-reducing effect conferred by heat stress preconditioning in isolated rat hearts.
Topics: Analysis of Variance; Animals; Camphanes; Cannabinoid Receptor Modulators; Cannabinoids; Endocannabinoids; Fever; Ischemic Preconditioning, Myocardial; Male; Myocardial Infarction; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Perfusion; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Time Factors | 2002 |
Anandamide induces cough in conscious guinea-pigs through VR1 receptors.
Topics: Aerosols; Animals; Arachidonic Acids; Calcium; Camphanes; Capsaicin; Cells, Cultured; Consciousness; Cough; Dronabinol; Endocannabinoids; Excitatory Amino Acid Antagonists; Guinea Pigs; Male; Nodose Ganglion; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant | 2002 |
Inhibition of interleukin-8 release in the human colonic epithelial cell line HT-29 by cannabinoids.
Topics: Arachidonic Acids; Benzoxazines; Camphanes; Cannabinoids; Cell Survival; Cyclohexanols; Dose-Response Relationship, Drug; HT29 Cells; Humans; Immunoblotting; Indoles; Interleukin-8; Kinetics; Morpholines; Naphthalenes; Piperidines; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Tumor Necrosis Factor-alpha | 2003 |
Cannabinoids inhibit gap junctional intercellular communication and activate ERK in a rat liver epithelial cell line.
Topics: Animals; Camphanes; Cannabinol; Cell Communication; Cell Line; Cyclic AMP; Dronabinol; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Flavonoids; Gap Junctions; Liver; MAP Kinase Kinase 1; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Phosphorylation; Piperidines; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Pyrazoles; Rats; Rats, Inbred F344; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; RNA, Messenger | 2003 |
Contribution of endocannabinoids in the endothelial protection afforded by ischemic preconditioning in the isolated rat heart.
Topics: Amides; Animals; Arachidonic Acids; Blotting, Western; Camphanes; Cannabinoid Receptor Modulators; Cannabinoids; Coronary Vessels; Endocannabinoids; Endothelium, Vascular; Ethanolamines; Fatty Acids, Unsaturated; Glycerides; Heart; Ischemic Preconditioning, Myocardial; Male; Myocardium; Nitroprusside; Palmitic Acids; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Serotonin; Vasodilation | 2003 |
A peripheral cannabinoid mechanism suppresses spinal fos protein expression and pain behavior in a rat model of inflammation.
Topics: Analgesics; Animals; Behavior, Animal; Benzoxazines; Camphanes; Cannabinoids; Carrageenan; Disease Models, Animal; Drug Administration Routes; Drug Interactions; Edema; Functional Laterality; Gene Expression Regulation; Immunohistochemistry; Inflammation; Male; Mechanoreceptors; Morpholines; Naphthalenes; Pain; Pain Measurement; Physical Stimulation; Piperidines; Proto-Oncogene Proteins c-fos; Pyrazoles; Rats; Rats, Sprague-Dawley; Rimonabant; Spinal Cord; Time Factors | 2003 |
Pharmacological characterisation of cannabinoid receptors inhibiting interleukin 2 release from human peripheral blood mononuclear cells.
Topics: Arachidonic Acids; Benzoxazines; Camphanes; Cell Survival; Cyclohexanols; Dose-Response Relationship, Drug; Dronabinol; Humans; Indoles; Interleukin-2; Leukocytes, Mononuclear; Morpholines; Naphthalenes; Phytohemagglutinins; Piperidines; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant | 2003 |
Vasodilator actions of abnormal-cannabidiol in rat isolated small mesenteric artery.
Topics: Animals; Calcium Channels; Calcium Chloride; Camphanes; Cannabidiol; Cannabinoid Receptor Antagonists; Dose-Response Relationship, Drug; Endothelium-Dependent Relaxing Factors; Gap Junctions; Heterotrimeric GTP-Binding Proteins; In Vitro Techniques; Male; Mesenteric Arteries; Myography; Piperidines; Potassium Channels, Calcium-Activated; Pyrazoles; Rats; Rats, Wistar; Receptors, Cannabinoid; Rimonabant; Vasodilation | 2003 |
A cannabinoid agonist differentially attenuates deep tissue hyperalgesia in animal models of cancer and inflammatory muscle pain.
Topics: Animals; Benzoxazines; Calcium Channel Blockers; Camphanes; Cannabinoids; Carrageenan; Catalepsy; Disease Models, Animal; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Fibrosarcoma; Haloperidol; Hand Strength; Humerus; Hyperalgesia; Male; Mice; Mice, Inbred C3H; Morpholines; Myositis; Naphthalenes; Neoplasm Transplantation; Neoplasms; Pain; Piperidines; Psychomotor Performance; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant | 2003 |
Selective activation of cannabinoid CB(2) receptors suppresses spinal fos protein expression and pain behavior in a rat model of inflammation.
Topics: Analgesics; Animals; Camphanes; Cannabinoids; Carrageenan; Disease Models, Animal; Drug Interactions; Hyperalgesia; Inflammation; Male; Nociceptors; Pain; Pain Threshold; Piperidines; Posterior Horn Cells; Proto-Oncogene Proteins c-fos; Pyrazoles; Rats; Rats, Sprague-Dawley; Reaction Time; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Drug; Rimonabant | 2003 |
Reduction of human monocytic cell neurotoxicity and cytokine secretion by ligands of the cannabinoid-type CB2 receptor.
Topics: Astrocytes; Camphanes; Cannabinoid Receptor Modulators; Cannabinoids; Cell Line; Cytokines; Dronabinol; Formazans; Gene Expression; Humans; Indoles; Indomethacin; L-Lactate Dehydrogenase; Ligands; Microglia; Monocytes; Morpholines; Nerve Degeneration; Neurotoxicity Syndromes; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Reverse Transcriptase Polymerase Chain Reaction; Rimonabant; RNA, Messenger; Temporal Lobe; Tetrazolium Salts | 2003 |
Endocannabinoids protect the rat isolated heart against ischaemia.
Topics: Amides; Animals; Arachidonic Acids; Biomarkers; Blotting, Western; Camphanes; Cannabinoid Receptor Modulators; Endocannabinoids; Ethanolamines; Glycerides; Heart; Imidazoles; L-Lactate Dehydrogenase; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; p38 Mitogen-Activated Protein Kinases; Palmitic Acids; Piperidines; Protein Kinase C; Pyrazoles; Pyridines; Rats; Rats, Sprague-Dawley; Rimonabant; Signal Transduction | 2003 |
Endogenous interleukin-1 receptor antagonist mediates anti-inflammatory and neuroprotective actions of cannabinoids in neurons and glia.
Topics: Animals; Anti-Inflammatory Agents; Camphanes; Cannabinoids; Cells, Cultured; Interleukin 1 Receptor Antagonist Protein; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Mice, Knockout; Neuroglia; Neurons; Neuroprotective Agents; Neurotoxins; Nitric Oxide; Piperidines; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Sialoglycoproteins | 2003 |
Inhibitory effect of anandamide on resiniferatoxin-induced sensory neuropeptide release in vivo and neuropathic hyperalgesia in the rat.
Topics: Amides; Animals; Arachidonic Acids; Calcitonin Gene-Related Peptide; Camphanes; Cannabinoids; Diterpenes; Dose-Response Relationship, Drug; Endocannabinoids; Ethanolamines; Hyperalgesia; Injections, Intravenous; Male; Neuropeptides; Neurotoxins; Palmitic Acids; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Rimonabant; Sciatic Nerve; Sciatic Neuropathy; Somatostatin | 2003 |
Inhibition of guinea-pig and human sensory nerve activity and the cough reflex in guinea-pigs by cannabinoid (CB2) receptor activation.
Topics: Animals; Camphanes; Cannabinoids; Capsaicin; Consciousness; Cough; Cyclohexanols; Dinoprost; Dose-Response Relationship, Drug; Guinea Pigs; Humans; Hypertonic Solutions; In Vitro Techniques; Male; Middle Aged; Neurons, Afferent; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Reflex; Rimonabant; Vagus Nerve | 2003 |
Cannabinoid receptors and T helper cells.
Topics: Animals; Bacterial Infections; Camphanes; Cannabinoid Receptor Antagonists; Cells, Cultured; DNA-Binding Proteins; Dronabinol; Drug Interactions; GATA3 Transcription Factor; Interferon-gamma; Interleukin-2; Interleukin-2 Receptor beta Subunit; Legionella pneumophila; Mice; Piperidines; Psychotropic Drugs; Pyrazoles; Receptors, Cannabinoid; Receptors, Interleukin; Reverse Transcriptase Polymerase Chain Reaction; Rimonabant; RNA, Messenger; Signal Transduction; Spleen; T-Lymphocytes, Helper-Inducer; Th2 Cells; Trans-Activators | 2004 |
Cannabinoids and the human uterus during pregnancy.
Topics: Adult; Arachidonic Acids; Camphanes; Dronabinol; Endocannabinoids; Female; Humans; In Vitro Techniques; Myometrium; Piperidines; Polyunsaturated Alkamides; Pregnancy; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Reverse Transcriptase Polymerase Chain Reaction; Rimonabant; RNA, Messenger; Uterine Contraction; Uterus | 2004 |
Cannabinoid receptor-mediated regulation of intracellular calcium by delta(9)-tetrahydrocannabinol in resting T cells.
Topics: Animals; Calcium; Camphanes; Cannabinoid Receptor Antagonists; Cannabinoids; Cells, Cultured; Dose-Response Relationship, Drug; Dronabinol; Female; Humans; Mice; Mice, Inbred Strains; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Rimonabant; T-Lymphocytes | 2004 |
Evidence that CB-1 and CB-2 cannabinoid receptors mediate antinociception in neuropathic pain in the rat.
Topics: Analgesics; Analysis of Variance; Animals; Behavior, Animal; Camphanes; Cyclohexanols; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Interactions; Ligation; Male; Nociceptors; Pain; Pain Measurement; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Reaction Time; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Spinal Nerves; Time Factors | 2004 |
Presynaptic cannabinoid CB(1) receptors are involved in the inhibition of the neurogenic vasopressor response during septic shock in pithed rats.
Topics: Animals; Autonomic Fibers, Postganglionic; Autonomic Fibers, Preganglionic; Blood Pressure; Camphanes; Capsaicin; Decerebrate State; Disease Models, Animal; Electric Stimulation; Germany; Imidazoles; Infusions, Intravenous; Lipopolysaccharides; Male; Norepinephrine; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptors, Presynaptic; Rimonabant; Shock, Septic; Solvents; Thiourea; Vagotomy; Vasomotor System; Vasopressins | 2004 |
Characterization of cannabinoid modulation of sensory neurotransmission in the rat isolated mesenteric arterial bed.
Topics: Animals; Benzofurans; Benzoxazines; Calcitonin Gene-Related Peptide; Camphanes; Cannabinoids; Capsaicin; Cyclohexanols; Dronabinol; Electric Stimulation; Indoles; Male; Mesenteric Arteries; Morpholines; Naphthalenes; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptors, Cannabinoid; Rimonabant; Vasodilation | 2004 |
The THC-induced suppression of Th1 polarization in response to Legionella pneumophila infection is not mediated by increases in corticosterone and PGE2.
Topics: Animals; Camphanes; Corticosterone; Dinoprostone; Dronabinol; Female; Hormone Antagonists; Immunosuppression Therapy; Interferon-gamma; Interleukin-12; Legionella pneumophila; Legionnaires' Disease; Mice; Mice, Inbred BALB C; Mifepristone; Piperidines; Pyrazoles; Radioimmunoassay; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Th1 Cells | 2004 |
Cannabinoid receptor agonists inhibit sensory nerve activation in guinea pig airways.
Topics: Analysis of Variance; Animals; Benzoxazines; Camphanes; Cannabinoid Receptor Antagonists; Disease Models, Animal; Electric Stimulation; Guinea Pigs; Male; Morpholines; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Naphthalenes; Neurokinin A; Piperidines; Probability; Pyrazoles; Respiratory Muscles; Rimonabant; Sensitivity and Specificity; Sensory Receptor Cells | 2004 |
Vanilloid TRPV1 receptor mediates the antihyperalgesic effect of the nonpsychoactive cannabinoid, cannabidiol, in a rat model of acute inflammation.
Topics: Administration, Oral; Animals; Camphanes; Cannabidiol; Capsaicin; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Therapy, Combination; Hyperalgesia; Inflammation; Italy; Male; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Receptors, Drug; Rimonabant; Time Factors | 2004 |
Activation of cannabinoid CB2 receptors suppresses C-fiber responses and windup in spinal wide dynamic range neurons in the absence and presence of inflammation.
Topics: Analgesics; Animals; Camphanes; Cannabinoids; Carrageenan; Edema; Electric Stimulation; Inflammation; Male; Nerve Fibers, Unmyelinated; Nociceptors; Piperidines; Posterior Horn Cells; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB2; Rimonabant | 2004 |
Synthetic cannabinoid WIN55,212-2 inhibits generation of inflammatory mediators by IL-1beta-stimulated human astrocytes.
Topics: Astrocytes; Benzoxazines; Camphanes; Cells, Cultured; Chemokines; Down-Regulation; Encephalitis; Gliosis; Humans; Inflammation Mediators; Interleukin-1; Morpholines; Naphthalenes; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Tumor Necrosis Factor-alpha | 2005 |
Endocannabinoids acting at cannabinoid-1 receptors regulate cardiovascular function in hypertension.
Topics: Amidohydrolases; Angiotensin II; Animals; Arachidonic Acids; Benzamides; Benzyl Compounds; Blood Pressure; Camphanes; Carbamates; Dronabinol; Endocannabinoids; Endothelium, Vascular; Hypertension; Male; Models, Cardiovascular; Myocardial Contraction; Myocardium; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Inbred Dahl; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Rimonabant; Up-Regulation; Vascular Resistance; Vasodilation; Ventricular Function, Left | 2004 |
Cannabinoid CB2 receptor activation inhibits mechanically evoked responses of wide dynamic range dorsal horn neurons in naïve rats and in rat models of inflammatory and neuropathic pain.
Topics: Action Potentials; Animals; Camphanes; Cannabinoids; Carrageenan; Disease Models, Animal; Inflammation; Ligation; Male; Neural Inhibition; Neuralgia; Nociceptors; Peripheral Nervous System Diseases; Physical Stimulation; Piperidines; Posterior Horn Cells; Pyrazoles; Rats; Rats, Sprague-Dawley; Reaction Time; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Sensory Receptor Cells; Spinal Nerves | 2004 |
Human brain endothelium: coexpression and function of vanilloid and endocannabinoid receptors.
Topics: Arachidonic Acids; Blood-Brain Barrier; Brain; Camphanes; Cannabinoid Receptor Agonists; Cannabinoid Receptor Modulators; Capsaicin; Cell Adhesion Molecules; Cells, Cultured; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Drug Interactions; Endocannabinoids; Endothelium, Vascular; Glycerides; Humans; Ion Channels; Microcirculation; Microfilament Proteins; Phosphoproteins; Phosphorylation; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; RNA, Messenger; TRPV Cation Channels | 2004 |
The nonpsychoactive component of marijuana cannabidiol modulates chemotaxis and IL-10 and IL-12 production of murine macrophages both in vivo and in vitro.
Topics: Adjuvants, Immunologic; Administration, Oral; Animals; Camphanes; Cannabidiol; Cell Migration Inhibition; Cells, Cultured; Chemotaxis; Cytokines; Down-Regulation; Interleukin-10; Interleukin-12; Macrophage Activation; Macrophages, Peritoneal; Male; Mice; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Up-Regulation | 2005 |
Cannabinoids depress excitatory neurotransmission between the subthalamic nucleus and the globus pallidus.
Topics: Animals; Benzoxazines; Camphanes; Cannabinoids; Dendrites; Electrophysiology; Excitatory Postsynaptic Potentials; Globus Pallidus; Mice; Morpholines; Naphthalenes; Neural Pathways; Neurons; Patch-Clamp Techniques; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; Subthalamic Nucleus; Synaptic Transmission | 2005 |
Peripheral, but not central effects of cannabidiol derivatives: mediation by CB(1) and unidentified receptors.
Topics: Animals; Binding, Competitive; Body Temperature; Camphanes; Cannabidiol; Capsaicin; Drug Interactions; Ear, External; Gastrointestinal Motility; Inflammation; Mice; Mice, Inbred ICR; Mice, Inbred Strains; Motor Activity; Pain Measurement; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant | 2005 |
Inhibitory effects of CB1 and CB2 receptor agonists on responses of DRG neurons and dorsal horn neurons in neuropathic rats.
Topics: Action Potentials; Animals; Arachidonic Acids; Behavior, Animal; Calcium; Camphanes; Cannabinoids; Capsaicin; Cells, Cultured; Diagnostic Imaging; Dose-Response Relationship, Drug; Drug Interactions; Evoked Potentials; Ganglia, Spinal; Hyperalgesia; Ligation; Male; Neural Inhibition; Neurons; Pain Measurement; Piperidines; Posterior Horn Cells; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Spinal Cord Diseases; Touch | 2005 |
Endogenous cannabinoid receptor agonists inhibit neurogenic inflammations in guinea pig airways.
Topics: Amides; Animals; Arachidonic Acids; Bronchi; Bronchoconstriction; Calcium Channel Blockers; Camphanes; Cannabinoid Receptor Agonists; Capsaicin; Electric Stimulation; Endocannabinoids; Ethanolamines; Guinea Pigs; Male; Muscle Contraction; Muscle, Smooth; Nerve Fibers, Unmyelinated; Neurogenic Inflammation; Organ Culture Techniques; Palmitic Acids; Piperidines; Polyunsaturated Alkamides; Potassium Channel Blockers; Pyrazoles; Receptors, Cannabinoid; Rimonabant; Substance P | 2005 |
Cannabinoid receptor antagonists SR141716 and SR144528 exhibit properties of partial agonists in experiments on isolated perfused rat heart.
Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Camphanes; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Cannabinoids; Dronabinol; Heart; Heart Rate; In Vitro Techniques; Myocardial Contraction; Piperidines; Pyrazoles; Rats; Receptors, Cannabinoid; Rimonabant | 2005 |
Antagonism of discriminative stimulus effects of delta(9)-THC and (R)-methanandamide in rats.
Topics: Animals; Arachidonic Acids; Camphanes; Discrimination Learning; Dose-Response Relationship, Drug; Dronabinol; Drug Antagonism; Male; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Stereoisomerism | 2006 |
Capsaicin evokes hypothermia independent of cannabinoid CB1 and CB2 receptors.
Topics: Anilides; Animals; Benzoxazines; Body Temperature; Calcium Channel Blockers; Camphanes; Capsaicin; Cinnamates; Hypothermia; Male; Morpholines; Naphthalenes; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; TRPV Cation Channels | 2005 |
Cannabinoid receptor agonists inhibit Ca(2+) influx to synaptosomes from rat brain.
Topics: Amides; Animals; Benzoxazines; Biological Transport; Brain; Calcium; Camphanes; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Dose-Response Relationship, Drug; Elapid Venoms; Endocannabinoids; Ethanolamines; In Vitro Techniques; Male; Morpholines; Naphthalenes; Palmitic Acids; Piperidines; Potassium Channel Blockers; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Synaptosomes | 2006 |
Methods evaluating cannabinoid and endocannabinoid effects on gastrointestinal functions.
Topics: Animals; Camphanes; Cannabinoid Receptor Modulators; Cannabinoids; Dose-Response Relationship, Drug; Endocannabinoids; Gastrointestinal Tract; Guinea Pigs; In Vitro Techniques; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant | 2006 |
Inhibition of an equilibrative nucleoside transporter by cannabidiol: a mechanism of cannabinoid immunosuppression.
Topics: Adenosine; Animals; Camphanes; Cannabidiol; Cell Line; Cell Proliferation; DNA; Dronabinol; Equilibrative Nucleoside Transporter 1; Immunosuppression Therapy; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Microglia; Nucleoside Transport Proteins; Piperidines; Psychotropic Drugs; Pyrazoles; Rimonabant; Thymidine; Tumor Necrosis Factor-alpha | 2006 |
Non-cannabinoid CB1, non-cannabinoid CB2 antinociceptive effects of several novel compounds in the PPQ stretch test in mice.
Topics: Acetaminophen; Amides; Analgesics; Animals; Arachidonic Acids; Benzamides; Benzoquinones; Camphanes; Capsaicin; Carbamates; Dose-Response Relationship, Drug; Dronabinol; Endocannabinoids; Ethanolamines; Hyperalgesia; Male; Mesencephalon; Mice; Mice, Inbred ICR; Narcotic Antagonists; Pain; Palmitic Acids; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Receptors, Opioid; Rimonabant; Spinal Cord; TRPV Cation Channels | 2006 |
Effects of a cannabinoid agonist on spinal nociceptive neurons in a rodent model of neuropathic pain.
Topics: Analgesics; Animals; Behavior, Animal; Benzoxazines; Camphanes; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Dose-Response Relationship, Drug; Electrophysiology; Hot Temperature; Hyperalgesia; In Vitro Techniques; Morpholines; Naphthalenes; Neurons; Nociceptors; Pain; Peripheral Nervous System Diseases; Piperidines; Posterior Horn Cells; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Spinal Cord | 2006 |
Involvement of cannabinoid receptors in inflammatory hypersensitivity to colonic distension in rats.
Topics: Animals; Benzoxazines; Calcium Channel Blockers; Camphanes; Colitis; Colon; Dose-Response Relationship, Drug; Indoles; Inflammation; Male; Manometry; Morpholines; Muscle Contraction; Muscle, Smooth; Naphthalenes; Nociceptors; Pain; Piperidines; Pressure; Pyrazoles; Rats; Rats, Wistar; Receptors, Cannabinoid; Rimonabant; Trinitrobenzenesulfonic Acid | 2006 |
In vivo modulation of LPS-induced alterations in brain and peripheral cytokines and HPA axis activity by cannabinoids.
Topics: Animals; Camphanes; Corticosterone; Dronabinol; Drug Interactions; Encephalitis; Hypothalamo-Hypophyseal System; Interferon-gamma; Interleukin-10; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Lymphocyte Count; Male; Neuroimmunomodulation; Neuroprotective Agents; Piperidines; Pituitary-Adrenal System; Pyrazoles; Rats; Rats, Sprague-Dawley; Rimonabant; Tumor Necrosis Factor-alpha | 2006 |
A novel role of cannabinoids: implication in the fever induced by bacterial lipopolysaccharide.
Topics: Animals; Benzoxazines; Binding, Competitive; Body Temperature; Camphanes; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Disease Models, Animal; Dronabinol; Fever; Interleukin-6; Lipopolysaccharides; Male; Morpholines; Naphthalenes; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Rimonabant | 2007 |
Cannabidiol displays unexpectedly high potency as an antagonist of CB1 and CB2 receptor agonists in vitro.
Topics: Animals; Anti-Inflammatory Agents; Benzoxazines; Brain; Camphanes; Cannabidiol; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Cell Membrane; CHO Cells; Cricetinae; Cricetulus; Cyclohexanes; Cyclohexanols; Dose-Response Relationship, Drug; Guanosine 5'-O-(3-Thiotriphosphate); Humans; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Knockout; Morpholines; Naphthalenes; Phenols; Piperidines; Protein Binding; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Rimonabant; Transfection | 2007 |
CB2 cannabinoid receptors promote mouse neural stem cell proliferation.
Topics: Animals; Arachidonic Acids; Camphanes; Cell Division; Cells, Cultured; Cerebral Cortex; Dronabinol; Excitatory Amino Acid Antagonists; Lipoprotein Lipase; Mice; Neurons; Phosphatidylinositol 3-Kinases; Piperidines; Proto-Oncogene Proteins c-akt; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Signal Transduction; Spheroids, Cellular; Stem Cells | 2007 |
Depolarization-induced rapid generation of 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand, in rat brain synaptosomes.
Topics: Animals; Arachidonic Acids; Brain; Calcimycin; Calcium Channel Blockers; Camphanes; Diglycerides; Endocannabinoids; Estrenes; Fatty Acids; Glycerides; Male; Membrane Potentials; Neuromuscular Depolarizing Agents; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Pyrrolidinones; Rats; Rats, Wistar; Receptors, Cannabinoid; Rimonabant; Synaptosomes | 2007 |
Anandamide-mediated CB1/CB2 cannabinoid receptor--independent nitric oxide production in rabbit aortic endothelial cells.
Topics: Animals; Arachidonic Acids; Benzofurans; Benzoxazines; Camphanes; Cannabinoid Receptor Modulators; Cells, Cultured; Chromones; Cyclohexanols; Dose-Response Relationship, Drug; Endocannabinoids; Endothelial Cells; Enzyme Inhibitors; GTP-Binding Protein alpha Subunits, Gi-Go; Morpholines; Naphthalenes; Nitric Oxide; Pertussis Toxin; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Piperidines; Polyunsaturated Alkamides; Proto-Oncogene Proteins c-akt; Pyrazoles; Rabbits; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Resorcinols; Rimonabant; Signal Transduction | 2007 |
Role of cannabinoid receptors in the regulation of cardiac contractility during ischemia/reperfusion.
Topics: Animals; Blood Pressure; Camphanes; Dronabinol; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Myocardial Reperfusion Injury; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptors, Cannabinoid; Rimonabant | 2006 |
Attenuation of allergic contact dermatitis through the endocannabinoid system.
Topics: Animals; Arachidonic Acids; Camphanes; Cannabinoid Receptor Modulators; Cannabinoids; Chemokines; Dermatitis, Allergic Contact; Dinitrofluorobenzene; Disease Models, Animal; Down-Regulation; Dronabinol; Endocannabinoids; Female; Glycerides; Mice; Mice, Inbred C57BL; Mice, Knockout; Oligonucleotide Array Sequence Analysis; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Skin; Up-Regulation | 2007 |
The effect of the palmitoylethanolamide analogue, palmitoylallylamide (L-29) on pain behaviour in rodent models of neuropathy.
Topics: Amides; Amines; Animals; Behavior, Animal; Camphanes; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Endocannabinoids; Ethanolamines; Gabapentin; gamma-Aminobutyric Acid; Hindlimb; Indoles; Injections, Intraperitoneal; Male; Pain; Pain Measurement; Pain Threshold; Palmitic Acids; Physical Stimulation; Piperidines; PPAR alpha; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Sciatic Neuropathy; Temperature; Zalcitabine | 2007 |
Virodhamine and CP55,940 modulate cAMP production and IL-8 release in human bronchial epithelial cells.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Analgesics; Arachidonic Acids; Blotting, Western; Bronchi; Camphanes; Cannabinoids; Cell Line; Colforsin; Cyclic AMP; Cyclohexanols; Dose-Response Relationship, Drug; Drug Antagonism; Epithelial Cells; Humans; Immunosuppressive Agents; Interleukin-8; Pertussis Toxin; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Reverse Transcriptase Polymerase Chain Reaction; Rimonabant; RNA, Messenger; Tumor Necrosis Factor-alpha | 2007 |
Activation of cannabinoid CB1 and CB2 receptors suppresses neuropathic nociception evoked by the chemotherapeutic agent vincristine in rats.
Topics: Animals; Benzoxazines; Body Weight; Camphanes; Cannabinoids; Catalepsy; Dose-Response Relationship, Drug; Hindlimb; Hyperesthesia; Injections, Intraperitoneal; Injections, Spinal; Male; Morphine; Morpholines; Naphthalenes; Neuralgia; Pain Measurement; Pain Threshold; Physical Stimulation; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Thermosensing; Vincristine | 2007 |
The antinociceptive effect of Delta9-tetrahydrocannabinol in the arthritic rat involves the CB(2) cannabinoid receptor.
Topics: Analgesics; Animals; Arthritis, Experimental; Camphanes; Dronabinol; Male; Mesencephalon; Pain; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Spinal Cord | 2007 |
Cannabinoid CB(2) receptor activation prevents bronchoconstriction and airway oedema in a model of gastro-oesophageal reflux.
Topics: Airway Obstruction; Animals; Benzoxazines; Bronchi; Bronchoconstriction; Camphanes; Cannabinoids; Capillary Permeability; Disease Models, Animal; Dose-Response Relationship, Drug; Esophagus; Extravasation of Diagnostic and Therapeutic Materials; Gastroesophageal Reflux; Guinea Pigs; Hydrochloric Acid; Male; Morpholines; Naphthalenes; Piperidines; Pulmonary Edema; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Respiratory Function Tests; Rimonabant; Trachea | 2007 |
The endogenous cannabinoid anandamide inhibits cromakalim-activated K+ currents in follicle-enclosed Xenopus oocytes.
Topics: Animals; Arachidonic Acids; Calcium; Camphanes; Cromakalim; Egtazic Acid; Endocannabinoids; Female; Glyburide; KATP Channels; Oocytes; Pertussis Toxin; Piperidines; Polyunsaturated Alkamides; Potassium Channel Blockers; Pyrazoles; Rimonabant; Xenopus laevis | 2007 |
The inhibition of monoacylglycerol lipase by URB602 showed an anti-inflammatory and anti-nociceptive effect in a murine model of acute inflammation.
Topics: Acute Disease; Animals; Biphenyl Compounds; Body Temperature; Camphanes; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Hindlimb; Hyperalgesia; Inflammation; Injections, Intraperitoneal; Male; Mice; Mice, Inbred C57BL; Monoacylglycerol Lipases; Pain; Pain Measurement; Pain Threshold; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant | 2007 |
Characterization of the vasorelaxant mechanisms of the endocannabinoid anandamide in rat aorta.
Topics: Animals; Aorta, Abdominal; Apamin; Arachidonic Acids; Benzamides; Calcitonin Gene-Related Peptide; Camphanes; Cannabinoid Receptor Modulators; Capsaicin; Carbamates; Charybdotoxin; Dose-Response Relationship, Drug; Endocannabinoids; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Isoindoles; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peptide Fragments; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Sulfonamides; Vasodilation | 2007 |
Topical WIN55212-2 alleviates intraocular hypertension in rats through a CB1 receptor mediated mechanism of action.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Benzoxazines; Blood Pressure; Calcium Channel Blockers; Camphanes; Heart Rate; Intraocular Pressure; Irritants; Male; Morpholines; Naphthalenes; Ocular Hypertension; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Timolol | 2008 |
Cannabinoid receptor 2 (CB2) mediates immunoglobulin class switching from IgM to IgE in cultures of murine-purified B lymphocytes.
Topics: Animals; B-Lymphocytes; Camphanes; Cannabinoids; Cyclohexanols; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Immunoglobulin Class Switching; Immunoglobulin E; Immunoglobulin M; In Vitro Techniques; Mice; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB2; Rimonabant; Th2 Cells | 2008 |
The cannabinoid delta-9-tetrahydrocannabinol mediates inhibition of macrophage chemotaxis to RANTES/CCL5: linkage to the CB2 receptor.
Topics: Animals; Arachidonic Acids; Camphanes; Chemokine CCL5; Chemotaxis; Cyclohexanols; Dronabinol; Female; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Mice, Knockout; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Receptors, CCR1; Receptors, CCR5; Receptors, G-Protein-Coupled; Rimonabant; RNA, Messenger; Signal Transduction | 2008 |
Discriminative stimulus effects of the cannabinoid CB1 receptor antagonist rimonabant in rats.
Topics: Animals; Arachidonic Acids; Avoidance Learning; Camphanes; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Drinking; Dronabinol; Hallucinogens; Indoles; Injections, Intraperitoneal; Lithium Chloride; Male; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Taste | 2008 |
First in vivo evidence for a functional interaction between chemokine and cannabinoid systems in the brain.
Topics: Analgesics; Animals; Benzoxazines; Camphanes; Chemokine CXCL12; Male; Morpholines; Naphthalenes; Pain; Periaqueductal Gray; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Receptors, CXCR4; Rimonabant | 2008 |
A saturated N-acylethanolamine other than N-palmitoyl ethanolamine with anti-inflammatory properties: a neglected story...
Topics: Amides; Animals; Anti-Inflammatory Agents; Benzoxazines; Body Temperature; Camphanes; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Cannabinoids; Ear Auricle; Edema; Endocannabinoids; Ethanolamines; Fatty Acids; Female; Inflammation; Mice; Mice, Inbred BALB C; Morpholines; Naphthalenes; Palmitic Acids; Passive Cutaneous Anaphylaxis; Piperidines; Pyrazoles; Rimonabant; Stearic Acids; Time Factors | 2008 |
N-arachidonylethanolamide-induced increase in aqueous humor outflow facility.
Topics: Amidohydrolases; Animals; Anterior Eye Segment; Aqueous Humor; Arachidonic Acids; Benzamides; Blotting, Western; Camphanes; Cannabinoid Receptor Antagonists; Cannabinoid Receptor Modulators; Carbamates; Chromatography, Thin Layer; Endocannabinoids; Organ Culture Techniques; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptors, Cannabinoid; Rimonabant; Swine; Trabecular Meshwork | 2008 |
Aqueous humor outflow effects of 2-arachidonylglycerol.
Topics: Animals; Aqueous Humor; Arachidonic Acids; Calcium-Calmodulin-Dependent Protein Kinases; Camphanes; Cannabinoid Receptor Modulators; Cytoskeleton; Dose-Response Relationship, Drug; Endocannabinoids; Enzyme Inhibitors; Flavonoids; Glycerides; Monoacylglycerol Lipases; Organ Culture Techniques; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Signal Transduction; Sus scrofa; Trabecular Meshwork | 2008 |
A CB(2) receptor agonist, A-836339, modulates wide dynamic range neuronal activity in neuropathic rats: contributions of spinal and peripheral CB(2) receptors.
Topics: Action Potentials; Animals; Camphanes; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Ganglia, Spinal; Male; Neurons; Peripheral Nervous System Diseases; Physical Stimulation; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB2; Rimonabant; Spinal Cord; Thiazoles | 2009 |
Antinociceptive effect of the cannabinoid agonist, WIN 55,212-2, in the orofacial and temporomandibular formalin tests.
Topics: Analgesics; Analgesics, Opioid; Anesthetics, Dissociative; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Benzoxazines; Camphanes; Facial Pain; Formaldehyde; Indomethacin; Inflammation; Ketamine; Male; Morphine; Morpholines; Motor Activity; Naphthalenes; Pain; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Temporomandibular Joint Disorders | 2010 |
Evaluation of prevalent phytocannabinoids in the acetic acid model of visceral nociception.
Topics: Acetic Acid; Analgesics; Animals; Anti-Obesity Agents; Camphanes; Cannabinoids; Cyclohexanols; Dose-Response Relationship, Drug; Dronabinol; Male; Mice; Mice, Inbred ICR; Motor Activity; Pain; Pain Measurement; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; RNA, Messenger | 2009 |
Signaling pathways from cannabinoid receptor-1 activation to inhibition of N-methyl-D-aspartic acid mediated calcium influx and neurotoxicity in dorsal root ganglion neurons.
Topics: Animals; Benzoxazines; Calcium; Camphanes; Cell Culture Techniques; Cell Death; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Ganglia, Spinal; Mice; Morpholines; N-Methylaspartate; Naphthalenes; Neurons; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Signal Transduction | 2009 |
Anandamide suppresses proliferation and cytokine release from primary human T-lymphocytes mainly via CB2 receptors.
Topics: Arachidonic Acids; Base Sequence; Camphanes; Cell Proliferation; Cytokines; DNA Primers; Endocannabinoids; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Microscopy, Confocal; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptor, Cannabinoid, CB2; Reverse Transcriptase Polymerase Chain Reaction; Rimonabant; T-Lymphocytes | 2010 |
The cannabinoid receptor agonist WIN 55,212-2 inhibits antigen-induced plasma extravasation in guinea pig airways.
Topics: Animals; Antigens; Benzoxazines; Camphanes; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Capillary Permeability; Dipeptides; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Guinea Pigs; Immunization; Indoles; Inflammation; Male; Morpholines; Naphthalenes; Neurokinin-1 Receptor Antagonists; Ovalbumin; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Respiratory Hypersensitivity; Rimonabant; Trachea | 2010 |
Pharmacological evaluation of the natural constituent of Cannabis sativa, cannabichromene and its modulation by Δ(9)-tetrahydrocannabinol.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Camphanes; Cannabinoids; Cannabis; Catalepsy; Dose-Response Relationship, Drug; Dronabinol; Hallucinogens; Hypothermia; Inflammation; Male; Mice; Mice, Inbred ICR; Motor Activity; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant | 2010 |
Human platelets express authentic CB₁ and CB₂ receptors.
Topics: Adult; Binding, Competitive; Blood Platelets; Calcium; Camphanes; Cyclic AMP; Cyclohexanols; Drug Interactions; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Gene Expression; Humans; Inositol 1,4,5-Trisphosphate; Integrin beta3; Male; Piperidines; Platelet Count; Protein Binding; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Tritium; Young Adult | 2010 |
Energetic metabolism and human sperm motility: impact of CB₁ receptor activation.
Topics: Camphanes; Diterpenes; Dose-Response Relationship, Drug; Energy Metabolism; Glucose; Glycolysis; Humans; Male; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; Rotenone; Sperm Motility; Spermatozoa; Uncoupling Agents | 2010 |
Cannabinoid receptor activation leads to massive mobilization of myeloid-derived suppressor cells with potent immunosuppressive properties.
Topics: Animals; Antibodies, Blocking; Bone Marrow; Camphanes; CD11b Antigen; Cells, Cultured; Dronabinol; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Immunosuppression Therapy; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Myeloid Cells; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Receptors, Chemokine; Rimonabant | 2010 |
Endocannabinoid 2-arachidonoylglycerol protects neurons against β-amyloid insults.
Topics: Amyloid beta-Peptides; Animals; Apoptosis; Arachidonic Acids; Benzodioxoles; Biphenyl Compounds; Camphanes; Cannabinoid Receptor Antagonists; Cannabinoid Receptor Modulators; Capsaicin; Cell Culture Techniques; Drug Interactions; Endocannabinoids; Glycerides; Hippocampus; Monoacylglycerol Lipases; Nerve Degeneration; Peptide Fragments; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Rimonabant; Signal Transduction | 2011 |
Pharmacological characterization of AM1710, a putative cannabinoid CB2 agonist from the cannabilactone class: antinociception without central nervous system side-effects.
Topics: Analgesics; Animals; Behavior, Animal; Binding, Competitive; Blood-Brain Barrier; Camphanes; Cannabinoids; Central Nervous System; Chromones; HEK293 Cells; Humans; Male; Mice; Pain Threshold; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Recombinant Proteins; Rimonabant | 2011 |
The hypothermic response to bacterial lipopolysaccharide critically depends on brain CB1, but not CB2 or TRPV1, receptors.
Topics: Analysis of Variance; Animals; Arachidonic Acids; Body Temperature Regulation; Brain; Camphanes; Capsaicin; Disease Models, Animal; Diterpenes; Endocannabinoids; Female; Hypothermia; Injections, Intraperitoneal; Injections, Intravenous; Injections, Intraventricular; Lipopolysaccharides; Male; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Long-Evans; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Signal Transduction; Sulfonamides; Time Factors; TRPV Cation Channels | 2011 |
Effects of cannabinoid agonists on sheep sphincter of oddi in vitro.
Topics: Analgesics; Animals; Arachidonic Acids; Benzoxazines; Camphanes; Cannabinoid Receptor Agonists; Cannabinoids; Carbachol; Cyclic GMP; Male; Morpholines; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Naphthalenes; NG-Nitroarginine Methyl Ester; Organ Culture Techniques; Piperidines; Pyrazoles; Rimonabant; Sheep; Sphincter of Oddi | 2011 |
Expression of fatty acid amide hydrolase (FAAH) in human, mouse, and rat urinary bladder and effects of FAAH inhibition on bladder function in awake rats.
Topics: Administration, Intravesical; Aged; Amidohydrolases; Animals; Blotting, Western; Camphanes; Enzyme Inhibitors; Female; Humans; Immunohistochemistry; Injections, Intravenous; Male; Mice; Mice, Inbred BALB C; Mucous Membrane; Oleic Acids; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Reverse Transcriptase Polymerase Chain Reaction; Rimonabant; RNA, Messenger; Urinary Bladder; Urination; Urodynamics; Urothelium; Wakefulness | 2012 |
3-Substituted pyrazole analogs of the cannabinoid type 1 (CB₁) receptor antagonist rimonabant: cannabinoid agonist-like effects in mice via non-CB₁, non-CB₂ mechanism.
Topics: Animals; Binding, Competitive; Body Temperature; Camphanes; Cell Membrane; CHO Cells; Cricetinae; Cyclohexanols; Dronabinol; Drug Inverse Agonism; Female; Freezing Reaction, Cataleptic; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Male; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Motor Activity; Pain Threshold; Piperidines; Pyrazoles; Radioligand Assay; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Structure-Activity Relationship; Transfection | 2012 |
Sex differences in cannabinoid 1 vs. cannabinoid 2 receptor-selective antagonism of antinociception produced by delta9-tetrahydrocannabinol and CP55,940 in the rat.
Topics: Analgesics; Animals; Camphanes; Cyclohexanols; Dose-Response Relationship, Drug; Dronabinol; Female; Male; Morphine; Motor Activity; Naloxone; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Sex Characteristics | 2012 |
Effects of palmitoylethanolamide on aqueous humor outflow.
Topics: Amides; Animals; Aqueous Humor; Blotting, Western; Camphanes; Dose-Response Relationship, Drug; Endocannabinoids; Enzyme Activation; Ethanolamines; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Organ Culture Techniques; Oxazoles; Palmitic Acids; Phosphorylation; Piperidines; PPAR alpha; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, G-Protein-Coupled; Rimonabant; Swine; Trabecular Meshwork; Tyrosine | 2012 |
Evaluation of the endogenous cannabinoid system in mediating the behavioral effects of dipyrone (metamizol) in mice.
Topics: Amidohydrolases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Camphanes; Dipyrone; Female; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Piperidines; Pyrazoles; Receptors, Cannabinoid; Rimonabant | 2012 |
The anxiolytic effect of cannabidiol on chronically stressed mice depends on hippocampal neurogenesis: involvement of the endocannabinoid system.
Topics: Animals; Anti-Anxiety Agents; Bromodeoxyuridine; Camphanes; Cannabidiol; Cannabinoid Receptor Antagonists; Cell Cycle; Cell Line, Transformed; Cell Proliferation; Disease Models, Animal; Feeding Behavior; Glial Fibrillary Acidic Protein; Hippocampus; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurogenesis; Piperidines; Pyrazoles; Rimonabant; Stress, Psychological; Thymidine Kinase | 2013 |
Sex differences in anti-allodynic, anti-hyperalgesic and anti-edema effects of Δ(9)-tetrahydrocannabinol in the rat.
Topics: Animals; Camphanes; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Dose-Response Relationship, Drug; Dronabinol; Edema; Estrous Cycle; Female; Hyperalgesia; Male; Motor Activity; Pain Measurement; Pain Threshold; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Rimonabant; Sex Characteristics; Time Factors | 2013 |
Blockade of cannabinoid receptors reduces inflammation, leukocyte accumulation and neovascularization in a model of sponge-induced inflammatory angiogenesis.
Topics: Animals; Camphanes; Cannabinoid Receptor Antagonists; Cytokines; Foreign Bodies; Foreign-Body Reaction; Leukocytes; Male; Mice; Mice, Inbred C57BL; Neovascularization, Pathologic; Piperidines; Polyesters; Polyurethanes; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Skin | 2013 |
Inhibition of peripheral FAAH depresses activities of bladder mechanosensitive nerve fibers of the rat.
Topics: Amidohydrolases; Animals; Camphanes; Cannabinoid Receptor Antagonists; Cannabinoids; Female; Nerve Fibers; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Rimonabant; Urinary Bladder | 2014 |
Inhibition of COX-2-mediated eicosanoid production plays a major role in the anti-inflammatory effects of the endocannabinoid N-docosahexaenoylethanolamine (DHEA) in macrophages.
Topics: Anilides; Animals; Arachidonic Acids; Camphanes; Cell Line; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dehydroepiandrosterone; Dinoprostone; Endocannabinoids; Indenes; Interferon-beta; Lipopolysaccharides; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myeloid Differentiation Factor 88; NF-kappa B; Nitric Oxide; Piperidines; PPAR gamma; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Rosiglitazone; Thiazolidinediones; Toll-Like Receptor 3; Toll-Like Receptor 4 | 2015 |
Antagonism of cannabinoid receptor 2 pathway suppresses IL-6-induced immunoglobulin IgM secretion.
Topics: Camphanes; Cannabinoids; Cell Line; Cell Proliferation; DNA-Binding Proteins; Humans; Immunoglobulin M; Indoles; Interleukin-6; PAX5 Transcription Factor; Piperidines; Proto-Oncogene Proteins c-bcl-6; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; STAT3 Transcription Factor | 2014 |
New modulatory pathways in micturition reflex function.
Topics: Amidohydrolases; Animals; Camphanes; Cannabinoid Receptor Antagonists; Cannabinoids; Female; Nerve Fibers; Piperidines; Pyrazoles; Rimonabant; Urinary Bladder | 2014 |
Spinal neuronal cannabinoid receptors mediate urodynamic effects of systemic fatty acid amide hydrolase (FAAH) inhibition in rats.
Topics: Amidohydrolases; Animals; Camphanes; Male; Oleic Acids; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Spinal Cord; Urinary Bladder Neck Obstruction; Urodynamics | 2016 |
Antinociceptive effects of JWH015 in female and male rats.
Topics: Analgesics; Animals; Camphanes; Cannabinoid Receptor Agonists; Dronabinol; Female; Freund's Adjuvant; Indoles; Male; Pain; Pain Measurement; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Sex Factors | 2018 |
Profiling molecular factors associated with pyknosis and developmental arrest induced by an opioid receptor antagonist and dihydroartemisinin in Plasmodium falciparum.
Topics: Antimalarials; Artemisinins; Benzylidene Compounds; Camphanes; Cannabinoid Receptor Antagonists; Cell Death; Chromatin; Dose-Response Relationship, Drug; Gene Expression Profiling; Glutathione; Naltrexone; Narcotic Antagonists; Oxidation-Reduction; Piperidines; Plasmodium falciparum; Pyrazoles; Rimonabant; Transcriptome | 2017 |
Cannabinoids Regulate the Diameter of Pericyte-Containing Retinal Capillaries in Rats.
Topics: Animals; Arachidonic Acids; Blotting, Western; Camphanes; Cannabinoid Receptor Antagonists; Cannabinoids; Capillaries; Endocannabinoids; Guanylate Cyclase; Immunohistochemistry; Male; Nitric Oxide Synthase; Pericytes; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptors, Cannabinoid; Retina; Rimonabant | 2017 |
Selective Action of N-Arachidonoyl Dopamine on Viability and Proliferation of Stromal Cells from Eutopic and Ectopic Endometrium.
Topics: Camphanes; Cannabinoid Receptor Antagonists; Capsaicin; Cell Proliferation; Cell Survival; Dopamine; Endometriosis; Endometrium; Female; Humans; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Stromal Cells | 2019 |