Compounds > sr141716
Page last updated: 2024-08-26

sr141716 and jzl 184

sr141716 has been researched along with jzl 184 in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (16.67)29.6817
2010's10 (83.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abdullah, RA; Carlson, BL; Cravatt, BF; Lichtman, AH; Long, JZ; Ramesh, D; Schlosburg, JE1
Arnold, A; Cravatt, BF; Hu, SS; Long, JZ; Mackie, K; Straiker, A; Wager-Miller, J1
Cravatt, BF; Kinsey, SG; Lichtman, AH; Long, JZ; O'Neal, ST1
Chen, C; Chen, X; Zhang, J1
Alhouayek, M; Cani, PD; Delzenne, NM; Lambert, DM; Muccioli, GG1
Hohmann, AG; Sciolino, NR; Zhou, W1
Shimizu, T; Tanaka, K; Yokotani, K1
Abdullah, R; Cravatt, BF; Kinsey, SG; Lichtman, AH; Ramesh, D; Selley, DE; Wise, LE1
Banks, ML; Bradshaw, HB; Crowe, MS; Gujjar, R; Kinsey, SG; Leishman, E; Mahadevan, A1
Vann, RE; Walentiny, DM; Wiley, JL1
Genewsky, A; Heinz, DE; Wotjak, CT1
Crowe, MS; Gross, JD; Jones, MS; Kinsey, SG; McKitrick, AW; Nass, SR; Siderovski, DP; Trexler, KR1

Other Studies

12 other study(ies) available for sr141716 and jzl 184

ArticleYear
Inhibitors of endocannabinoid-metabolizing enzymes reduce precipitated withdrawal responses in THC-dependent mice.
    The AAPS journal, 2009, Volume: 11, Issue:2

    Topics: Amidohydrolases; Animals; Benzamides; Benzodioxoles; Cannabinoid Receptor Modulators; Carbamates; Dronabinol; Endocannabinoids; Enzyme Inhibitors; Hallucinogens; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Monoacylglycerol Lipases; Motor Activity; Piperidines; Postural Balance; Psychomotor Performance; Pyrazoles; Rimonabant; Substance Withdrawal Syndrome

2009
Monoacylglycerol lipase limits the duration of endocannabinoid-mediated depolarization-induced suppression of excitation in autaptic hippocampal neurons.
    Molecular pharmacology, 2009, Volume: 76, Issue:6

    Topics: Animals; Arachidonic Acids; Benzodioxoles; Biphenyl Compounds; Cannabinoid Receptor Modulators; Cell Line; Cells, Cultured; Endocannabinoids; Excitatory Postsynaptic Potentials; Glycerides; Hippocampus; Humans; Mice; Monoacylglycerol Lipases; Neurons; Piperidines; Presynaptic Terminals; Pyrazoles; Rimonabant

2009
Inhibition of endocannabinoid catabolic enzymes elicits anxiolytic-like effects in the marble burying assay.
    Pharmacology, biochemistry, and behavior, 2011, Volume: 98, Issue:1

    Topics: Amidohydrolases; Animals; Anti-Anxiety Agents; Anxiety Disorders; Benzodioxoles; Cannabinoid Receptor Modulators; Diazepam; Disease Models, Animal; Dronabinol; Endocannabinoids; Enzyme Inhibitors; Male; Mice; Mice, Inbred C57BL; Monoacylglycerol Lipases; Obsessive-Compulsive Disorder; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant

2011
Endocannabinoid 2-arachidonoylglycerol protects neurons against β-amyloid insults.
    Neuroscience, 2011, Mar-31, Volume: 178

    Topics: Amyloid beta-Peptides; Animals; Apoptosis; Arachidonic Acids; Benzodioxoles; Biphenyl Compounds; Camphanes; Cannabinoid Receptor Antagonists; Cannabinoid Receptor Modulators; Capsaicin; Cell Culture Techniques; Drug Interactions; Endocannabinoids; Glycerides; Hippocampus; Monoacylglycerol Lipases; Nerve Degeneration; Peptide Fragments; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Rimonabant; Signal Transduction

2011
Increasing endogenous 2-arachidonoylglycerol levels counteracts colitis and related systemic inflammation.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2011, Volume: 25, Issue:8

    Topics: Animals; Arachidonic Acids; Benzodioxoles; Colitis; Disease Models, Animal; Endocannabinoids; Endotoxemia; Enzyme Inhibitors; Glycerides; Humans; Indoles; Inflammation; Inflammation Mediators; Inflammatory Bowel Diseases; Male; Mice; Mice, Inbred C57BL; Monoacylglycerol Lipases; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Trinitrobenzenesulfonic Acid

2011
Enhancement of endocannabinoid signaling with JZL184, an inhibitor of the 2-arachidonoylglycerol hydrolyzing enzyme monoacylglycerol lipase, produces anxiolytic effects under conditions of high environmental aversiveness in rats.
    Pharmacological research, 2011, Volume: 64, Issue:3

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Arachidonic Acids; Benzodioxoles; Cannabinoid Receptor Modulators; Catalepsy; Diazepam; Endocannabinoids; Glycerides; Male; Monoacylglycerol Lipases; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Rimonabant; Signal Transduction

2011
Stimulatory and inhibitory roles of brain 2-arachidonoylglycerol in bombesin-induced central activation of adrenomedullary outflow in rats.
    Journal of pharmacological sciences, 2013, Volume: 121, Issue:2

    Topics: Adrenal Medulla; Animals; Arachidonic Acids; Benzodioxoles; Bombesin; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Catecholamines; Cyclooxygenase Inhibitors; Drug Interactions; Endocannabinoids; Glycerides; Indomethacin; Injections, Intraventricular; Lipoprotein Lipase; Male; Monoacylglycerol Lipases; Neurotransmitter Agents; Paraventricular Hypothalamic Nucleus; Piperidines; Pyrazoles; Rats; Rimonabant

2013
Repeated low-dose administration of the monoacylglycerol lipase inhibitor JZL184 retains cannabinoid receptor type 1-mediated antinociceptive and gastroprotective effects.
    The Journal of pharmacology and experimental therapeutics, 2013, Volume: 345, Issue:3

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arachidonic Acids; Benzodioxoles; Brain Chemistry; Cyclohexanols; Diclofenac; Dose-Response Relationship, Drug; Dronabinol; Drug Tolerance; Endocannabinoids; Glycerides; Guanosine 5'-O-(3-Thiotriphosphate); Male; Mice; Mice, Inbred C57BL; Monoacylglycerol Lipases; Pain Measurement; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; Stomach Ulcer; Substance Withdrawal Syndrome; Substance-Related Disorders

2013
Combined inhibition of monoacylglycerol lipase and cyclooxygenases synergistically reduces neuropathic pain in mice.
    British journal of pharmacology, 2015, Volume: 172, Issue:7

    Topics: Analgesics; Animals; Benzodioxoles; Cannabinoid Receptor Antagonists; Cyclooxygenase Inhibitors; Diclofenac; Drug Synergism; Drug Therapy, Combination; Eicosanoids; Endocannabinoids; Fatty Acids; Hyperalgesia; Male; Mice, Inbred C57BL; Monoacylglycerol Lipases; Neuralgia; Piperidines; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rimonabant; Spinal Cord

2015
Phenotypic assessment of THC discriminative stimulus properties in fatty acid amide hydrolase knockout and wildtype mice.
    Neuropharmacology, 2015, Volume: 93

    Topics: Amidohydrolases; Analysis of Variance; Animals; Arachidonic Acids; Benzodioxoles; Brain; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Carbamates; Discrimination, Psychological; Dose-Response Relationship, Drug; Dronabinol; Endocannabinoids; Enzyme Inhibitors; Glycerides; Male; Mice; Mice, Knockout; Piperazines; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rimonabant

2015
Enhanced anandamide signaling reduces flight behavior elicited by an approaching robo-beetle.
    Neuropharmacology, 2017, Volume: 126

    Topics: Amidohydrolases; Animals; Anti-Anxiety Agents; Anxiety; Arachidonic Acids; Avoidance Learning; Behavior, Animal; Benzamides; Benzodioxoles; Cannabinoid Receptor Agonists; Carbamates; Diazepam; Endocannabinoids; Fear; Male; Mice, Inbred C57BL; Monoacylglycerol Lipases; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant

2017
Novel behavioral assays of spontaneous and precipitated THC withdrawal in mice.
    Drug and alcohol dependence, 2018, Oct-01, Volume: 191

    Topics: Animals; Behavior, Animal; Benzodioxoles; Cannabinoid Receptor Agonists; Dronabinol; Indoles; Male; Marijuana Abuse; Mice; Mice, Inbred C57BL; Naphthalenes; Piperidines; Pyrazoles; Rimonabant; Substance Withdrawal Syndrome

2018