Page last updated: 2024-08-26

sr141716 and cp-55,940

sr141716 has been researched along with cp-55,940 in 27 studies

Research

Studies (27)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	3 (11.11)	18.2507
2000's	4 (14.81)	29.6817
2010's	20 (74.07)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Blond, O; Briley, EM; Felder, CC; Joyce, KE; Lai, Y; Ma, AL; Mackie, K; Mansouri, J; Mitchell, RL	1
Abood, ME; Compton, DR; Martin, BR; Showalter, VM	1
Govaerts, SJ; Hermans, E; Kanyonyo, M; Lambert, DM; Poupaert, JH	1
Bianchi, A; Cruciani, G; Fichera, M; Musumarra, G	1
Bouchard, G; Carrupt, PA; Happaerts, T; Lambert, DM; Ooms, F; Oscari, O; Testa, B; Wouters, J	1
Chavatte, P; Depreux, P; Farce, A; Goossens, JF; Hénichart, JP; Lambert, DM; Millet, R; Muccioli, GG; Poupaert, JH; Stern, E	1
Abood, M; Fleischer, D; Hurst, D; Hyatt, S; Jones, J; Kapur, A; Lewis, D; Lynch, D; McAllister, S; Reggio, P; Roche, M; Seltzman, H; Shi, S; Umejiego, U	1
Fang, G; Li, M; Meng, T; Peng, H; Shen, J; Wang, J; Wang, X; Xie, X; Xiong, B; Zhang, Y	1
Brogi, S; Corelli, F; Di Marzo, V; Ligresti, A; Mugnaini, C; Pasquini, S; Tafi, A	1
Behnia, K; Carlson, KE; Ewing, WR; Gu, Z; Hong, Y; Johnghar, S; Keim, WJ; Miller, KJ; Murugesan, N; O'Tanyi, E; Pelleymounter, MA; Rohrbach, KW; Tian, Y; Yang, Y; Zhu, Y	1
Bräse, S; Hinz, S; Karcz, T; Meliciani, I; Müller, CE; Nieger, M; Rempel, V; Volz, N; Wenzel, W	1
Almehizia, AA; Alqarni, MH; Bartlow, P; Cao, H; Cheng, T; Feng, R; Gao, Y; Gertsch, J; Kurihara, N; Myint, KZ; Roodman, GD; Teramachi, J; Tong, Q; Wang, L; Xie, XQ; Yang, P	1
Bolognini, D; Brizzi, A; Caradonna, NP; Cascio, MG; Corelli, F; De Rosa, M; Di Marzo, V; Ligresti, A; Mugnaini, C; Pasquini, S; Pertwee, RG	1
Almehizia, AA; Alqarni, MH; Feng, R; Myint, KZ; Ouyang, Q; Tong, Q; Wang, L; Xie, XQ; Yang, P	1
Douglas, JT; Fantegrossi, WE; Ford, BM; Franks, LN; Prather, PL; Prisinzano, TE; Vasiljevik, T	1
Bräse, S; Gläser, F; Müller, CE; Nieger, M; Rempel, V; Volz, N	1
Ahn, KH; Kendall, DA; Shim, JY	1
Feng, R; Myint, KZ; Ouyang, Q; Tong, Q; Xie, XQ; Yang, P	1
Fuchs, A; Hinz, S; Karcz, T; Koetter, U; Lehr, M; Müller, CE; Rempel, V	1
Decker, M; Heilmann, J; Huang, G; Nimczick, M; Pemp, D; Stadtmüller, P	1
Chen, JZ; Chen, LL; Han, S; Pu, JB; Qian, HY; Xie, X; Zhang, FF	1
Cawston, EE; Connor, M; Di Marzo, V; Glass, M; Silvestri, R	1
Baillie, G; Distinto, R; Falzoi, M; Jagerovic, N; Lazzari, P; Manca, I; Morales, P; Murineddu, G; Pinna, GA; Pira, M; Ross, R; Sani, M; Zanda, M	1
Carrillo-Salinas, FJ; Fernández-Ruiz, J; Franco, R; Gómez-Cañas, M; Goya, P; Guaza, C; Hurst, DP; Jagerovic, N; Lagartera, L; Morales, P; Navarro, G; Pazos, R; Reggio, PH	1
Chung, S; Dangott, LJ; Huang, H; Kier, AB; Landrock, D; Landrock, KK; Li, S; Martin, GG; McIntosh, AL; Schroeder, F	1
Abate, M; Arena, C; Bertini, S; Bifulco, M; Chicca, A; Ciaglia, E; Digiacomo, M; Gado, F; Gertsch, J; Lapillo, M; Macchia, M; Manera, C; Poli, G; Tuccinardi, T	1
Cheng, J; McCorvy, JD; Tan, L; Yan, W	1

Reviews

1 review(s) available for sr141716 and cp-55,940

Article	Year
Biased Ligands of G Protein-Coupled Receptors (GPCRs): Structure-Functional Selectivity Relationships (SFSRs) and Therapeutic Potential. Journal of medicinal chemistry, 2018, 11-21, Volume: 61, Issue:22 Topics: Animals; Drug Discovery; Humans; Ligands; Receptors, G-Protein-Coupled; Signal Transduction; Structure-Activity Relationship	2018

Other Studies

26 other study(ies) available for sr141716 and cp-55,940

Article	Year
Comparison of the pharmacology and signal transduction of the human cannabinoid CB1 and CB2 receptors. Molecular pharmacology, 1995, Volume: 48, Issue:3 Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Amidohydrolases; Animals; Arachidonic Acids; Base Sequence; Binding, Competitive; Calcium; Calcium Channel Blockers; Cannabinoids; CHO Cells; Cricetinae; Endocannabinoids; Enzyme Activation; Humans; Intracellular Fluid; Ion Channels; Kinetics; Mice; Molecular Sequence Data; Phospholipases; Polyunsaturated Alkamides; Rats; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Drug; Signal Transduction; Transfection	1995
Evaluation of binding in a transfected cell line expressing a peripheral cannabinoid receptor (CB2): identification of cannabinoid receptor subtype selective ligands. The Journal of pharmacology and experimental therapeutics, 1996, Volume: 278, Issue:3 Topics: Animals; Binding, Competitive; Brain; Cannabinoids; Cell Membrane; Cells, Cultured; CHO Cells; Cricetinae; Cyclohexanols; Guanine Nucleotides; Humans; Ligands; Rats; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Drug; Recombinant Proteins; Sodium; Structure-Activity Relationship; Transfection	1996
3-Alkyl-(5,5'-diphenyl)imidazolidineiones as new cannabinoid receptor ligands. Bioorganic & medicinal chemistry letters, 1999, Aug-02, Volume: 9, Issue:15 Topics: Animals; Cannabinoids; CHO Cells; Cricetinae; Humans; Imidazoles; Ligands; Piperidines; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Structure-Activity Relationship; Transfection	1999
A 3D-QSAR study on the structural requirements for binding to CB(1) and CB(2) cannabinoid receptors. Journal of medicinal chemistry, 2000, Jun-15, Volume: 43, Issue:12 Topics: Arachidonic Acids; Cannabinoids; Drug Design; Endocannabinoids; Indoles; Ligands; Models, Biological; Models, Molecular; Polyunsaturated Alkamides; Receptors, Cannabinoid; Receptors, Drug; Structure-Activity Relationship	2000
Exploration of the pharmacophore of 3-alkyl-5-arylimidazolidinediones as new CB(1) cannabinoid receptor ligands and potential antagonists: synthesis, lipophilicity, affinity, and molecular modeling. Journal of medicinal chemistry, 2002, Apr-25, Volume: 45, Issue:9 Topics: Animals; Binding, Competitive; Cannabinoids; Cerebellum; CHO Cells; Chromatography, High Pressure Liquid; Cricetinae; Crystallography, X-Ray; Humans; Hydantoins; In Vitro Techniques; Ligands; Models, Molecular; Molecular Conformation; Radioligand Assay; Rats; Receptors, Cannabinoid; Receptors, Drug; Structure-Activity Relationship	2002
Novel 4-oxo-1,4-dihydroquinoline-3-carboxamide derivatives as new CB2 cannabinoid receptors agonists: synthesis, pharmacological properties and molecular modeling. Journal of medicinal chemistry, 2006, Jan-12, Volume: 49, Issue:1 Topics: Crystallography, X-Ray; Humans; Models, Molecular; Molecular Structure; Quinolones; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Structure-Activity Relationship	2006
Biarylpyrazole inverse agonists at the cannabinoid CB1 receptor: importance of the C-3 carboxamide oxygen/lysine3.28(192) interaction. Journal of medicinal chemistry, 2006, Oct-05, Volume: 49, Issue:20 Topics: Amides; Amino Acid Sequence; Animals; Binding Sites; Binding, Competitive; Calcium; Cell Line; Humans; In Vitro Techniques; Ligands; Lysine; Models, Molecular; Molecular Sequence Data; Molecular Structure; Mutation; Neurons; Oxygen; Pyrazoles; Radioligand Assay; Rats; Receptor, Cannabinoid, CB1; Stereoisomerism; Superior Cervical Ganglion; Thermodynamics	2006
Discovery of benzhydrylpiperazine derivatives as CB1 receptor inverse agonists via privileged structure-based approach. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Animals; Benzhydryl Compounds; Cells, Cultured; CHO Cells; Cricetinae; Cricetulus; Inhibitory Concentration 50; Male; Molecular Structure; Piperazines; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Recombinant Proteins; Structure-Activity Relationship	2010
Three-dimensional quantitative structure-selectivity relationships analysis guided rational design of a highly selective ligand for the cannabinoid receptor 2. European journal of medicinal chemistry, 2011, Volume: 46, Issue:2 Topics: Computer Simulation; Drug Design; Humans; Ligands; Models, Molecular; Molecular Structure; Quantitative Structure-Activity Relationship; Quinolones; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Recombinant Proteins; Stereoisomerism	2011
Characterization of a novel and selective CB1 antagonist as a radioligand for receptor occupancy studies. Bioorganic & medicinal chemistry letters, 2011, Nov-15, Volume: 21, Issue:22 Topics: Animals; Anti-Obesity Agents; Brain; Humans; Obesity; Radiography; Radioligand Assay; Rats; Receptor, Cannabinoid, CB1	2011
7-Alkyl-3-benzylcoumarins: a versatile scaffold for the development of potent and selective cannabinoid receptor agonists and antagonists. Journal of medicinal chemistry, 2012, Sep-27, Volume: 55, Issue:18 Topics: Animals; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Chemical Phenomena; CHO Cells; Coumarins; Cricetinae; Cricetulus; Drug Design; Humans; Molecular Docking Simulation; Protein Conformation; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Structure-Activity Relationship; Substrate Specificity	2012
Lead discovery, chemistry optimization, and biological evaluation studies of novel biamide derivatives as CB2 receptor inverse agonists and osteoclast inhibitors. Journal of medicinal chemistry, 2012, Nov-26, Volume: 55, Issue:22 Topics: Alkylation; Animals; Benzeneacetamides; Binding, Competitive; Bone Marrow; Cell Death; Cells, Cultured; CHO Cells; Cricetinae; Cyclic AMP; High-Throughput Screening Assays; Humans; Models, Molecular; Molecular Structure; Osteoclasts; Osteogenesis; Receptor, Cannabinoid, CB2; Structure-Activity Relationship	2012
Investigations on the 4-quinolone-3-carboxylic acid motif. 6. Synthesis and pharmacological evaluation of 7-substituted quinolone-3-carboxamide derivatives as high affinity ligands for cannabinoid receptors. European journal of medicinal chemistry, 2012, Volume: 58 Topics: Animals; Cell Line; CHO Cells; Cricetinae; Dogs; Dose-Response Relationship, Drug; Humans; Ligands; Molecular Structure; Quinolones; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Structure-Activity Relationship	2012
Novel triaryl sulfonamide derivatives as selective cannabinoid receptor 2 inverse agonists and osteoclast inhibitors: discovery, optimization, and biological evaluation. Journal of medicinal chemistry, 2013, Mar-14, Volume: 56, Issue:5 Topics: Animals; Biological Assay; Cannabinoid Receptor Agonists; CHO Cells; Cricetinae; Ligands; Macrophages; Mice; Osteoclasts; Quantitative Structure-Activity Relationship; Receptor, Cannabinoid, CB2; Sulfonamides	2013
Design, synthesis, and biological evaluation of aminoalkylindole derivatives as cannabinoid receptor ligands with potential for treatment of alcohol abuse. Journal of medicinal chemistry, 2013, Jun-13, Volume: 56, Issue:11 Topics: Alcoholism; Animals; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; CHO Cells; Conditioning, Classical; Cricetinae; Cricetulus; Drug Design; Drug Inverse Agonism; Ethanol; Humans; Indoles; Ligands; Mice; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Self Administration; Structure-Activity Relationship	2013
Antagonists for the orphan G-protein-coupled receptor GPR55 based on a coumarin scaffold. Journal of medicinal chemistry, 2013, Jun-13, Volume: 56, Issue:11 Topics: Allosteric Site; Animals; CHO Cells; Coumarins; Cricetinae; HEK293 Cells; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Receptors, Cannabinoid; Receptors, G-Protein-Coupled; Structure-Activity Relationship	2013
Molecular basis of cannabinoid CB1 receptor coupling to the G protein heterotrimer Gαiβγ: identification of key CB1 contacts with the C-terminal helix α5 of Gαi. The Journal of biological chemistry, 2013, Nov-08, Volume: 288, Issue:45 Topics: GTP-Binding Protein alpha Subunits; GTP-Binding Protein beta Subunits; GTP-Binding Protein gamma Subunits; HEK293 Cells; Humans; Models, Molecular; Protein Structure, Quaternary; Protein Structure, Secondary; Receptor, Cannabinoid, CB1	2013
Trisubstituted Sulfonamides: a New Chemotype for Development of Potent and Selective CB ACS medicinal chemistry letters, 2013, Apr-11, Volume: 4, Issue:4 Topics:	2013
Magnolia Extract, Magnolol, and Metabolites: Activation of Cannabinoid CB2 Receptors and Blockade of the Related GPR55. ACS medicinal chemistry letters, 2013, Jan-10, Volume: 4, Issue:1 Topics:	2013
Design, synthesis and in vitro evaluation of novel uni- and bivalent ligands for the cannabinoid receptor type 1 with variation of spacer length and structure. Bioorganic & medicinal chemistry letters, 2014, Sep-01, Volume: 24, Issue:17 Topics: Amides; Amines; Cannabinoid Receptor Agonists; Carboxylic Acids; Dose-Response Relationship, Drug; Drug Design; Humans; Ligands; Molecular Structure; Receptor, Cannabinoid, CB1; Structure-Activity Relationship	2014
Development of Quinoline-2,4(1H,3H)-diones as Potent and Selective Ligands of the Cannabinoid Type 2 Receptor. Journal of medicinal chemistry, 2015, Aug-13, Volume: 58, Issue:15 Topics: Animals; CHO Cells; Cricetinae; Cricetulus; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Ligands; Mice; Mice, Inbred C57BL; Molecular Docking Simulation; Multiple Sclerosis; Quantitative Structure-Activity Relationship; Quinolines; Receptor, Cannabinoid, CB2	2015
Distinct Temporal Fingerprint for Cyclic Adenosine Monophosphate (cAMP) Signaling of Indole-2-carboxamides as Allosteric Modulators of the Cannabinoid Receptors. Journal of medicinal chemistry, 2015, Aug-13, Volume: 58, Issue:15 Topics: Allosteric Regulation; Cyclic AMP; HEK293 Cells; Humans; Indoles; Piperidines; Potassium Channels, Inwardly Rectifying; Receptor, Cannabinoid, CB1; Signal Transduction	2015
A critical review of both the synthesis approach and the receptor profile of the 8-chloro-1-(2',4'-dichlorophenyl)-N-piperidin-1-yl-1,4,5,6-tetrahydrobenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide and analogue derivatives. European journal of medicinal chemistry, 2016, Oct-04, Volume: 121 Topics: Drug Discovery; Piperidines; Protein Binding; Pyrazoles; Receptor, Cannabinoid, CB1; Structure-Activity Relationship	2016
Chromenopyrazole, a Versatile Cannabinoid Scaffold with in Vivo Activity in a Model of Multiple Sclerosis. Journal of medicinal chemistry, 2016, 07-28, Volume: 59, Issue:14 Topics: Dose-Response Relationship, Drug; HEK293 Cells; Humans; Models, Molecular; Molecular Structure; Multiple Sclerosis; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Structure-Activity Relationship	2016
FABP1: A Novel Hepatic Endocannabinoid and Cannabinoid Binding Protein. Biochemistry, 2016, 09-20, Volume: 55, Issue:37 Topics: Animals; Endocannabinoids; Fatty Acid-Binding Proteins; Female; Fluorescent Dyes; Humans; Liver; Male; Mice; Mice, Inbred C57BL; Receptors, Cannabinoid	2016
Polypharmacological profile of 1,2-dihydro-2-oxo-pyridine-3-carboxamides in the endocannabinoid system. European journal of medicinal chemistry, 2018, Jun-25, Volume: 154 Topics: Dose-Response Relationship, Drug; Endocannabinoids; Humans; Molecular Docking Simulation; Molecular Structure; Pyridines; Receptors, Cannabinoid; Structure-Activity Relationship; Tumor Cells, Cultured; U937 Cells	2018