Page last updated: 2024-08-26

sr141716 and am-356

sr141716 has been researched along with am-356 in 51 studies

Research

Studies (51)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	7 (13.73)	18.2507
2000's	40 (78.43)	29.6817
2010's	4 (7.84)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Fernández-Ruiz, JJ; Makriyannis, A; Muñoz, RM; Ramos, JA; Romero, J; Villanua, MA	1
Brodkin, J; Moerschbaecher, JM	1
Bouaboula, M; Casellas, P; Derocq, JM; Marchand, J; Rinaldi-Carmona, M; Ségui, M	1
Bertrand, P; Imperato, A; Jeantaud, B; Petitet, F	1
Brown, S; Derleth, C; Hsieh, C; Mackie, K	1
Chaytor, AT; Evans, WH; Griffith, TM; Martin, PE; Randall, MD	1
Bonner, TI; Buckley, NE; Compton, DR; Járai, Z; Kunos, G; Lake, KD; Martin, BR; Mezey, E; Razdan, RK; Varga, K; Wagner, JA; Zimmer, A; Zimmer, AM	1
Goutopoulos, A; Järbe, TU; Lamb, RJ; Lin, S; Makriyannis, A	1
Van den Bossche, I; Vanheel, B	1
Brockie, HC; Craib, SJ; Di Marzo, V; Gibson, TM; Leslie, M; Pashmi, G; Pertwee, RG; Ross, RA	1
Van de Voorde, J; Vanheel, B	1
Honoré, E; Lazdunski, M; Maingret, F; Patel, AJ	1
Bátkai, S; Járai, Z; Kunos, G; Wagner, JA	1
Järbe, TU; Lamb, RJ; Lin, S; Makriyannis, A	1
Christopoulos, A; Wilson, K	1
Bottrill, FE; Ford, WR; Hiley, CR; Ho, WS; White, R	1
Boachie-Ansah, G; Grainger, J	1
Fowler, CJ; Jacobsson, SO; Wallin, T	1
Darmani, NA	1
Baker, D; Bifulco, M; Bisogno, T; Bridges, D; Brooks, JW; Brown, P; Di Marzo, V; Hankey, DJ; Jaggar, SI; Ledent, C; Pryce, G; Rice, AS	1
Chapnick, BM; Howlett, AC; Mukhopadhyay, S	1
Adinolfi, B; Breschi, MC; Calderone, V; Martinotti, E; Nieri, P; Testai, L	1
Kaminski, NE; Li, J; Wang, DH	1
Järbe, TU; Lamb, RJ; Liu, Q; Makriyannis, A	2
Díaz-Laviada, I; Ruiz-Llorente, L; Sánchez, AM; Sánchez, MG	2
DiPatrizio, NV; Järbe, TU; Li, C; Makriyannis, A	2
Köfalvi, A; Ledent, C; Sperlágh, B; Vizi, ES	1
Baskfield, CY; Martin, BR; Wiley, JL	1
Goldberg, SR; Justinova, Z; Redhi, GH; Solinas, M; Tanda, G	1
Adler-Graschinsky, E; Briones, R; Huidobro-Toro, JP; Orliac, ML; Poblete, IM	1
Kaminski, NE; Wang, DH; Wang, Y	1
Järbe, TU; Liu, Q; Makriyannis, A	1
Hille, B; Lauckner, JE; Mackie, K	1
Ahn, KH; D'Antona, AM; Kendall, DA	1
Chizhmakov, I; Fedorenko, A; Krishtal, O; Lozovaya, N; Savelyev, I	1
Cichewicz, DL; Haller, VL; Welch, SP	1
Howlett, AC; McCollum, L; Mukhopadhyay, S	1
Fischer, MJ; Messlinger, K	1
Connor, M; Roberts, LA; Ross, HR	1
Ginsburg, BC; Lamb, RJ; McMahon, LR	1
Järbe, TU; Li, C; Makriyannis, A; Vadivel, SK	1
Järbe, TU; Li, C; Liu, Q; Makriyannis, A	1
Goldberg, SR; Luchicchi, A; Melis, M; Muntoni, AL; Pillolla, G; Pistis, M; Yasar, S	1
Amigou, E; Cohen-Salmon, M; Ezan, P; Froger, N; Giaume, C; Orellana, JA; Sáez, JC	1
Baskfield, CY; Matthew Walentiny, D; Vann, RE; Wiley, JL	1
Altun, A; Bagcivan, I; Durmus, N; Kaya, T; Sarac, B; Sencan, M; Turan, M	1
Halikhedkar, A; Järbe, TU; LeMay, BJ; Makriyannis, A; Vadivel, SK; Wood, J; Zvonok, A	1
Castellón, EA; Contreras, HR; Gallegos, I; Huidobro, C; Llanos, MN; Orellana-Serradell, O; Poblete, CE; Sanchez, C	1

Other Studies

51 other study(ies) available for sr141716 and am-356

Article	Year
Time course of the effects of different cannabimimetics on prolactin and gonadotrophin secretion: evidence for the presence of CB1 receptors in hypothalamic structures and their involvement in the effects of cannabimimetics. Biochemical pharmacology, 1997, Jun-15, Volume: 53, Issue:12 Topics: Animals; Arachidonic Acids; Autoradiography; Dronabinol; Endocannabinoids; Gonadotropins, Pituitary; Hypothalamus; Male; Piperidines; Polyunsaturated Alkamides; Prolactin; Pyrazoles; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Time Factors	1997
SR141716A antagonizes the disruptive effects of cannabinoid ligands on learning in rats. The Journal of pharmacology and experimental therapeutics, 1997, Volume: 282, Issue:3 Topics: Animals; Arachidonic Acids; Cannabinoids; Dose-Response Relationship, Drug; Dronabinol; Endocannabinoids; Learning; Male; Morphine; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rimonabant	1997
The endogenous cannabinoid anandamide is a lipid messenger activating cell growth via a cannabinoid receptor-independent pathway in hematopoietic cell lines. FEBS letters, 1998, Apr-03, Volume: 425, Issue:3 Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium-Calmodulin-Dependent Protein Kinases; Camphanes; Cannabinoids; Cell Division; CHO Cells; Cricetinae; Cyclohexanols; Endocannabinoids; Enzyme Activation; Gene Expression Regulation; Mice; Pertussis Toxin; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; RNA, Messenger; Signal Transduction; Transfection; Tumor Cells, Cultured; Virulence Factors, Bordetella	1998
Cannabinoid penetration into mouse brain as determined by ex vivo binding. European journal of pharmacology, 1999, Jun-25, Volume: 374, Issue:3 Topics: Animals; Arachidonic Acids; Benzoxazines; Binding, Competitive; Brain; Cannabinoids; Cyclohexanols; Male; Mice; Morpholines; Naphthalenes; Perfusion; Piperidines; Pyrazoles; Radioligand Assay; Receptors, Drug; Rimonabant; Tritium	1999
Internalization and recycling of the CB1 cannabinoid receptor. Journal of neurochemistry, 1999, Volume: 73, Issue:2 Topics: Acids; Ammonium Chloride; Animals; Arachidonic Acids; Benzoxazines; Calcium Channel Blockers; Cannabinoids; Cells, Cultured; Clathrin; Coated Vesicles; Cyclohexanols; Dronabinol; Drug Tolerance; Endocytosis; Endosomes; Excitatory Amino Acid Antagonists; GTP-Binding Proteins; Immunosuppressive Agents; Morpholines; Mutagenesis; Naphthalenes; Phosphorylation; Piperidines; Protein Binding; Protein Structure, Tertiary; Pyrazoles; Rats; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Transfection; Up-Regulation; Virulence Factors, Bordetella	1999
The endothelial component of cannabinoid-induced relaxation in rabbit mesenteric artery depends on gap junctional communication. The Journal of physiology, 1999, Oct-15, Volume: 520 Pt 2 Topics: Acetylcholine; Animals; Arachidonic Acids; Benzofurans; Cannabinoid Receptor Modulators; Cannabinoids; COS Cells; Endocannabinoids; Gap Junctions; Glycyrrhetinic Acid; Indomethacin; Isoquinolines; Male; Mesenteric Artery, Superior; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Phenylephrine; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rabbits; Receptors, Cannabinoid; Receptors, Drug; Rimonabant	1999
Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors. Proceedings of the National Academy of Sciences of the United States of America, 1999, Nov-23, Volume: 96, Issue:24 Topics: Animals; Arachidonic Acids; Cannabidiol; Cannabinoids; Dronabinol; Endocannabinoids; Endothelium, Vascular; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Nitric Oxide; Piperidines; Polyunsaturated Alkamides; Potassium Channels; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Vasodilation; Vasodilator Agents	1999
Effects of Delta 9-tetrahydrocannabinol, (R)-methanandamide, SR 141716,and d-amphetamine before and during daily Delta 9-tetrahydrocannabinol dosing. European journal of pharmacology, 2000, Jun-16, Volume: 398, Issue:2 Topics: Animals; Arachidonic Acids; Behavior, Animal; Conditioning, Operant; Dextroamphetamine; Dose-Response Relationship, Drug; Dronabinol; Drug Interactions; Drug Tolerance; Male; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Rimonabant; Time Factors	2000
Influence of cannabinoids on the delayed rectifier in freshly dissociated smooth muscle cells of the rat aorta. British journal of pharmacology, 2000, Volume: 131, Issue:1 Topics: Animals; Aorta, Thoracic; Arachidonic Acid; Arachidonic Acids; Benzoxazines; Cannabinoids; Endocannabinoids; Female; Morpholines; Muscle, Smooth, Vascular; Naphthalenes; Piperidines; Polyunsaturated Alkamides; Potassium Channels; Pyrazoles; Rats; Rats, Wistar; Rimonabant	2000
Structure-activity relationship for the endogenous cannabinoid, anandamide, and certain of its analogues at vanilloid receptors in transfected cells and vas deferens. British journal of pharmacology, 2001, Volume: 132, Issue:3 Topics: Animals; Arachidonic Acids; Benzoxazines; Binding, Competitive; Biological Transport; Calcium; Calcium Channel Blockers; Cannabinoids; Capsaicin; CHO Cells; Cricetinae; Drug Interactions; Electric Stimulation; Endocannabinoids; Enzyme Inhibitors; Male; Mice; Morpholines; Muscle Contraction; Naphthalenes; Phenylmethylsulfonyl Fluoride; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Radioligand Assay; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Structure-Activity Relationship; Transfection; TRPV Cation Channels; Vas Deferens	2001
Regional differences in anandamide- and methanandamide-induced membrane potential changes in rat mesenteric arteries. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 296, Issue:2 Topics: Animals; Arachidonic Acids; Benzoxazines; Biological Factors; Calcium Channel Blockers; Cannabinoids; Capsaicin; Electrophysiology; Endocannabinoids; Endothelium, Vascular; Membrane Potentials; Mesenteric Arteries; Morpholines; Muscle, Smooth, Vascular; Naphthalenes; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptors, Drug; Rimonabant; Vasodilator Agents	2001
The endocannabinoid anandamide is a direct and selective blocker of the background K(+) channel TASK-1. The EMBO journal, 2001, Jan-15, Volume: 20, Issue:1-2 Topics: Animals; Arachidonic Acids; Cannabinoid Receptor Modulators; Cannabinoids; Cerebellum; Chlorocebus aethiops; COS Cells; Endocannabinoids; Halothane; Humans; Membrane Potentials; Mice; Motor Neurons; Nerve Tissue Proteins; Neurons; Piperidines; Polyunsaturated Alkamides; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Tandem Pore Domain; Pyrazoles; Rats; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Drug; Recombinant Proteins; Rimonabant; Transfection	2001
Hemodynamic effects of cannabinoids: coronary and cerebral vasodilation mediated by cannabinoid CB(1) receptors. European journal of pharmacology, 2001, Jul-06, Volume: 423, Issue:2-3 Topics: Animals; Arachidonic Acids; Blood Pressure; Brain; Cannabinoids; Coronary Circulation; Coronary Vessels; Dronabinol; Endocannabinoids; Heart Rate; Hemodynamics; Male; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Vascular Resistance; Vasodilation	2001
(R)-methanandamide and Delta 9-THC as discriminative stimuli in rats: tests with the cannabinoid antagonist SR-141716 and the endogenous ligand anandamide. Psychopharmacology, 2001, Volume: 156, Issue:4 Topics: Adjuvants, Immunologic; Animals; Arachidonic Acids; Cannabinoid Receptor Modulators; Cannabinoids; Discrimination, Psychological; Dose-Response Relationship, Drug; Dronabinol; Endocannabinoids; Ligands; Male; Piperidines; Polyunsaturated Alkamides; Psychotropic Drugs; Pyrazoles; Rats; Rats, Sprague-Dawley; Reaction Time; Rimonabant	2001
Interaction of anandamide with the M(1) and M(4) muscarinic acetylcholine receptors. Brain research, 2001, Oct-05, Volume: 915, Issue:1 Topics: Acetylcholine; Animals; Arachidonic Acids; Binding Sites; Binding, Competitive; Brain; Calcium Channel Blockers; Cannabinoid Receptor Modulators; Cannabinoids; CHO Cells; Cricetinae; Endocannabinoids; Memory; Muscarinic Antagonists; N-Methylscopolamine; Parasympatholytics; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Quinuclidinyl Benzilate; Radioligand Assay; Receptor, Muscarinic M1; Receptor, Muscarinic M4; Receptors, Cannabinoid; Receptors, Drug; Receptors, Muscarinic; Rimonabant; Tritium	2001
Mechanisms of anandamide-induced vasorelaxation in rat isolated coronary arteries. British journal of pharmacology, 2001, Volume: 134, Issue:4 Topics: Amides; Animals; Arachidonic Acids; Capsaicin; Coronary Vessels; Dose-Response Relationship, Drug; Endocannabinoids; Endothelium, Vascular; Ethanolamines; Gap Junctions; Glycyrrhetinic Acid; In Vitro Techniques; Indoles; Indomethacin; Male; Palmitic Acids; Peptides; Piperidines; Polyunsaturated Alkamides; Potassium Channel Blockers; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Serotonin; Tetraethylammonium; Vasodilation	2001
Anandamide-induced relaxation of sheep coronary arteries: the role of the vascular endothelium, arachidonic acid metabolites and potassium channels. British journal of pharmacology, 2001, Volume: 134, Issue:5 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 4-Aminopyridine; Animals; Apamin; Arachidonic Acid; Arachidonic Acids; Barium; Calcium Channel Blockers; Cannabinoid Receptor Modulators; Cannabinoids; Capsaicin; Coronary Vessels; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Endocannabinoids; Endothelium, Vascular; Enzyme Inhibitors; Fatty Acids, Unsaturated; Glyburide; In Vitro Techniques; Indomethacin; Miconazole; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptides; Phenylmethylsulfonyl Fluoride; Piperidines; Polyunsaturated Alkamides; Potassium; Potassium Channel Blockers; Potassium Channels; Pyrazoles; Receptors, Drug; Rimonabant; Sheep; Tetraethylammonium; Vasoconstrictor Agents; Vasodilation	2001
Inhibition of rat C6 glioma cell proliferation by endogenous and synthetic cannabinoids. Relative involvement of cannabinoid and vanilloid receptors. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:3 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Arachidonic Acids; Cannabinoid Receptor Modulators; Cannabinoids; Capsaicin; Cell Division; Glioma; Piperidines; Pyrazoles; Rats; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Tumor Cells, Cultured	2001
The potent emetogenic effects of the endocannabinoid, 2-AG (2-arachidonoylglycerol) are blocked by delta(9)-tetrahydrocannabinol and other cannnabinoids. The Journal of pharmacology and experimental therapeutics, 2002, Volume: 300, Issue:1 Topics: Animals; Antiemetics; Arachidonic Acids; Cannabinoid Receptor Modulators; Cannabinoids; Cyclohexanols; Dose-Response Relationship, Drug; Dronabinol; Emetics; Endocannabinoids; Female; Glycerides; Humans; Male; Motor Activity; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Shrews	2002
Arvanil-induced inhibition of spasticity and persistent pain: evidence for therapeutic sites of action different from the vanilloid VR1 receptor and cannabinoid CB(1)/CB(2) receptors. European journal of pharmacology, 2002, Mar-29, Volume: 439, Issue:1-3 Topics: Animals; Arachidonic Acids; Benzoxazines; Camphanes; Cannabinoid Receptor Modulators; Capsaicin; Disease Models, Animal; Dose-Response Relationship, Drug; Genotype; Mice; Mice, Inbred Strains; Mice, Knockout; Morpholines; Multiple Sclerosis; Muscle Spasticity; Naphthalenes; Pain; Pain Measurement; Piperidines; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant	2002
Anandamide-induced vasorelaxation in rabbit aortic rings has two components: G protein dependent and independent. American journal of physiology. Heart and circulatory physiology, 2002, Volume: 282, Issue:6 Topics: Animals; Aorta; Arachidonic Acids; Cannabinoids; Capsaicin; Endocannabinoids; Endothelium, Vascular; Enzyme Inhibitors; Gap Junctions; GTP-Binding Proteins; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pertussis Toxin; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rabbits; Receptors, Calcitonin Gene-Related Peptide; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Virulence Factors, Bordetella	2002
R+-methanandamide inhibits tracheal response to endogenously released acetylcholine via capsazepine-sensitive receptors. European journal of pharmacology, 2003, Jan-10, Volume: 459, Issue:1 Topics: Acetylcholine; Animals; Arachidonic Acids; Atropine; Benzoxazines; Cannabinoid Receptor Modulators; Capsaicin; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Indoles; Male; Morpholines; Muscle Contraction; Muscle, Smooth; Naphthalenes; Piperidines; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Trachea	2003
Anandamide-induced depressor effect in spontaneously hypertensive rats: role of the vanilloid receptor. Hypertension (Dallas, Tex. : 1979), 2003, Volume: 41, Issue:3 Pt 2 Topics: Animals; Arachidonic Acids; Blood Pressure; Calcitonin Gene-Related Peptide; Capsaicin; Endocannabinoids; Hypertension; Male; Mesenteric Arteries; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Cannabinoid; Receptors, Drug; Rimonabant	2003
(R)-Methanandamide and delta9-tetrahydrocannabinol-induced operant rate decreases in rats are not readily antagonized by SR-141716A. European journal of pharmacology, 2003, Apr-11, Volume: 466, Issue:1-2 Topics: Animals; Arachidonic Acids; Behavior, Animal; Conditioning, Operant; Dronabinol; Drug Interactions; Hallucinogens; Injections, Intraperitoneal; Male; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Rimonabant	2003
Activation of phosphoinositide 3-kinase/PKB pathway by CB(1) and CB(2) cannabinoid receptors expressed in prostate PC-3 cells. Involvement in Raf-1 stimulation and NGF induction. Cellular signalling, 2003, Volume: 15, Issue:9 Topics: 3-Phosphoinositide-Dependent Protein Kinases; Animals; Arachidonic Acids; Blotting, Northern; Blotting, Western; Cell Division; Cell Line, Tumor; Cell Survival; Cells, Cultured; Cerebellum; Chromones; Dronabinol; Flavonoids; Gene Expression Regulation; Humans; Liver; Lymphocytes; Male; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; Morpholines; Nerve Growth Factor; PC12 Cells; Phosphorylation; Piperidines; Polymerase Chain Reaction; Prostate; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-raf; Pyrazoles; Rats; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Signal Transduction; Spleen	2003
The cannabinoid receptor antagonist SR-141716 does not readily antagonize open-field effects induced by the cannabinoid receptor agonist (R)-methanandamide in rats. Pharmacology, biochemistry, and behavior, 2003, Volume: 75, Issue:4 Topics: Animals; Arachidonic Acids; Dose-Response Relationship, Drug; Exploratory Behavior; Male; Motor Activity; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Reaction Time; Receptor, Cannabinoid, CB1; Rimonabant	2003
Cannabinoids inhibit the release of [3H]glutamate from rodent hippocampal synaptosomes via a novel CB1 receptor-independent action. The European journal of neuroscience, 2003, Volume: 18, Issue:7 Topics: Analgesics; Animals; Arachidonic Acids; Benzoxazines; Cannabinoids; Capsaicin; Chromatography, High Pressure Liquid; Cyclohexanols; Dose-Response Relationship, Drug; Drug Interactions; Glutamic Acid; Hippocampus; Male; Morpholines; Naphthalenes; Piperidines; Pyrazoles; Radioactivity; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Rimonabant; Synaptosomes; Tritium	2003
Enhancement of androgen receptor expression induced by (R)-methanandamide in prostate LNCaP cells. FEBS letters, 2003, Dec-18, Volume: 555, Issue:3 Topics: Androgen Receptor Antagonists; Arachidonic Acids; Cannabinoids; Cell Division; Cell Line, Tumor; DNA, Neoplasm; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Male; Mitogens; Phosphoinositide-3 Kinase Inhibitors; Piperidines; Prostatic Neoplasms; Pyrazoles; Receptors, Androgen; Rimonabant; Thymidine; Tritium; Up-Regulation	2003
Differential effects of delta9-tetrahydrocannabinol and methanandamide in CB1 knockout and wild-type mice. The Journal of pharmacology and experimental therapeutics, 2004, Volume: 309, Issue:1 Topics: Analysis of Variance; Animals; Arachidonic Acids; Dronabinol; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant	2004
The endogenous cannabinoid anandamide and its synthetic analog R(+)-methanandamide are intravenously self-administered by squirrel monkeys. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Jun-08, Volume: 25, Issue:23 Topics: Animals; Arachidonic Acids; Cannabinoid Receptor Modulators; Cocaine; Endocannabinoids; Infusions, Intravenous; Male; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptor, Cannabinoid, CB1; Reinforcement, Psychology; Rimonabant; Saimiri; Self Administration; Stereoisomerism; Substance-Related Disorders	2005
Anandamide elicits an acute release of nitric oxide through endothelial TRPV1 receptor activation in the rat arterial mesenteric bed. The Journal of physiology, 2005, Oct-15, Volume: 568, Issue:Pt 2 Topics: Anilides; Animals; Arachidonic Acids; Cannabinoid Receptor Antagonists; Capsaicin; Cinnamates; Cyclic GMP; Diterpenes; Dose-Response Relationship, Drug; Endocannabinoids; Endothelium, Vascular; In Vitro Techniques; Male; Mesenteric Artery, Superior; Nitric Oxide; Nitroarginine; Perfusion; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Sprague-Dawley; Rimonabant; RNA, Messenger; TRPV Cation Channels; Vasodilation	2005
VR1-mediated depressor effects during high-salt intake: role of anandamide. Hypertension (Dallas, Tex. : 1979), 2005, Volume: 46, Issue:4 Topics: Animals; Arachidonic Acids; Blood Pressure; Cannabinoid Receptor Modulators; Cannabinoids; Capsaicin; Dose-Response Relationship, Drug; Drug Combinations; Endocannabinoids; Male; Mesenteric Arteries; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Rimonabant; Sodium, Dietary; Time Factors; TRPV Cation Channels	2005
Antagonism of discriminative stimulus effects of delta(9)-THC and (R)-methanandamide in rats. Psychopharmacology, 2006, Volume: 184, Issue:1 Topics: Animals; Arachidonic Acids; Camphanes; Discrimination Learning; Dose-Response Relationship, Drug; Dronabinol; Drug Antagonism; Male; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Stereoisomerism	2006
The cannabinoid agonist WIN55,212-2 increases intracellular calcium via CB1 receptor coupling to Gq/11 G proteins. Proceedings of the National Academy of Sciences of the United States of America, 2005, Dec-27, Volume: 102, Issue:52 Topics: Analgesics; Animals; Arachidonic Acids; Benzoxazines; Calcium; Cannabinoids; Cell Line; Cyclohexanols; Cytoplasm; DNA, Complementary; Dronabinol; Endocannabinoids; Endoplasmic Reticulum; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Fura-2; Glycerides; GTP-Binding Protein alpha Subunits, Gq-G11; Hippocampus; Humans; Immunosuppressive Agents; Morpholines; Naphthalenes; Neurons; Pertussis Toxin; Piperidines; Protein Binding; Protein Conformation; Pyrazoles; Rats; Receptor, Cannabinoid, CB1; Rimonabant; Ryanodine; Time Factors; Type C Phospholipases	2005
Mutations of CB1 T210 produce active and inactive receptor forms: correlations with ligand affinity, receptor stability, and cellular localization. Biochemistry, 2006, May-02, Volume: 45, Issue:17 Topics: Amino Acid Sequence; Amino Acid Substitution; Arachidonic Acids; Benzoxazines; Cells, Cultured; Cyclic AMP; Dronabinol; Drug Stability; Guanosine 5'-O-(3-Thiotriphosphate); Hot Temperature; Humans; Kidney; Ligands; Morpholines; Mutation; Naphthalenes; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; Threonine	2006
The agonists for nociceptors are ubiquitous, but the modulators are specific: P2X receptors in the sensory neurons are modulated by cannabinoids. Pflugers Archiv : European journal of physiology, 2006, Volume: 453, Issue:3 Topics: Adenosine Triphosphate; Animals; Arachidonic Acids; Benzoxazines; Calcium Channel Blockers; Cannabinoids; Electrophysiology; Endocannabinoids; Ganglia, Spinal; Morpholines; Naphthalenes; Neurons, Afferent; Nociceptors; Nodose Ganglion; Patch-Clamp Techniques; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X2; Receptors, Purinergic P2X3; Rimonabant	2006
Non-cannabinoid CB1, non-cannabinoid CB2 antinociceptive effects of several novel compounds in the PPQ stretch test in mice. European journal of pharmacology, 2006, Sep-28, Volume: 546, Issue:1-3 Topics: Acetaminophen; Amides; Analgesics; Animals; Arachidonic Acids; Benzamides; Benzoquinones; Camphanes; Capsaicin; Carbamates; Dose-Response Relationship, Drug; Dronabinol; Endocannabinoids; Ethanolamines; Hyperalgesia; Male; Mesencephalon; Mice; Mice, Inbred ICR; Narcotic Antagonists; Pain; Palmitic Acids; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Receptors, Opioid; Rimonabant; Spinal Cord; TRPV Cation Channels	2006
Discriminative stimulus functions of AM-1346, a CB1R selective anandamide analog in rats trained with Delta9-THC or (R)-methanandamide (AM-356). Psychopharmacology, 2006, Volume: 188, Issue:3 Topics: Analysis of Variance; Animals; Arachidonic Acids; Dextroamphetamine; Discrimination Learning; Dose-Response Relationship, Drug; Dronabinol; Hallucinogens; Injections, Intraperitoneal; Male; Morphine; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Regression Analysis; Reinforcement Schedule; Rimonabant; Time Factors	2006
Anandamide-mediated CB1/CB2 cannabinoid receptor--independent nitric oxide production in rabbit aortic endothelial cells. The Journal of pharmacology and experimental therapeutics, 2007, Volume: 321, Issue:3 Topics: Animals; Arachidonic Acids; Benzofurans; Benzoxazines; Camphanes; Cannabinoid Receptor Modulators; Cells, Cultured; Chromones; Cyclohexanols; Dose-Response Relationship, Drug; Endocannabinoids; Endothelial Cells; Enzyme Inhibitors; GTP-Binding Protein alpha Subunits, Gi-Go; Morpholines; Naphthalenes; Nitric Oxide; Pertussis Toxin; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Piperidines; Polyunsaturated Alkamides; Proto-Oncogene Proteins c-akt; Pyrazoles; Rabbits; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Resorcinols; Rimonabant; Signal Transduction	2007
Cannabinoid and vanilloid effects of R(+)-methanandamide in the hemisected meningeal preparation. Cephalalgia : an international journal of headache, 2007, Volume: 27, Issue:5 Topics: Animals; Arachidonic Acids; Calcitonin Gene-Related Peptide; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Meninges; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptors, Cannabinoid; Rimonabant; TRPV Cation Channels	2007
Methanandamide activation of a novel current in mouse trigeminal ganglion sensory neurons in vitro. Neuropharmacology, 2008, Volume: 54, Issue:1 Topics: Animals; Arachidonic Acids; Calcium Channel Blockers; Diterpenes; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Dronabinol; Drug Interactions; Electric Stimulation; Endocannabinoids; Female; In Vitro Techniques; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons, Afferent; Patch-Clamp Techniques; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rimonabant; Trigeminal Ganglion; TRPV Cation Channels	2008
Cannabinoid agonists differentially substitute for the discriminative stimulus effects of Delta(9)-tetrahydrocannabinol in C57BL/6J mice. Psychopharmacology, 2008, Volume: 198, Issue:4 Topics: Animals; Arachidonic Acids; Benzoxazines; Cannabinoids; Cyclohexanols; Data Interpretation, Statistical; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Dronabinol; Drug Interactions; Hallucinogens; Male; Mice; Mice, Inbred C57BL; Morpholines; Naphthalenes; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Reinforcement Schedule; Rimonabant	2008
Effects of AM1346, a high-affinity CB1 receptor selective anandamide analog, on open-field behavior in rats. Behavioural pharmacology, 2007, Volume: 18, Issue:7 Topics: Animals; Arachidonic Acids; Behavior, Animal; Defecation; Dose-Response Relationship, Drug; Dronabinol; Drug Inverse Agonism; Exploratory Behavior; Grooming; Male; Motor Activity; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Rimonabant; Stereotyped Behavior; Vocalization, Animal	2007
Discriminative stimulus effects of the cannabinoid CB1 receptor antagonist rimonabant in rats. Psychopharmacology, 2008, Volume: 198, Issue:4 Topics: Animals; Arachidonic Acids; Avoidance Learning; Camphanes; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Drinking; Dronabinol; Hallucinogens; Indoles; Injections, Intraperitoneal; Lithium Chloride; Male; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Taste	2008
Discriminative stimulus functions in rats of AM1346, a high-affinity CB1R selective anandamide analog. Psychopharmacology, 2009, Volume: 203, Issue:2 Topics: Animals; Arachidonic Acids; Discrimination, Psychological; Dose-Response Relationship, Drug; Dronabinol; Endocannabinoids; Ligands; Male; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Rimonabant; Structure-Activity Relationship	2009
Endogenous fatty acid ethanolamides suppress nicotine-induced activation of mesolimbic dopamine neurons through nuclear receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, Dec-17, Volume: 28, Issue:51 Topics: Amides; Amidohydrolases; Animals; Appetite Depressants; Arachidonic Acids; Benzamides; Cannabinoid Receptor Antagonists; Carbamates; Dopamine; Endocannabinoids; Enzyme Activation; Enzyme Inhibitors; Ethanolamines; Injections, Intraventricular; Lipoxygenase Inhibitors; Male; Neurons; Nicotine; Oleic Acids; Organ Culture Techniques; Palmitic Acids; Patch-Clamp Techniques; Piperidines; PPAR alpha; Protein-Tyrosine Kinases; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Rimonabant; Ventral Tegmental Area	2008
Cannabinoids prevent the opposite regulation of astroglial connexin43 hemichannels and gap junction channels induced by pro-inflammatory treatments. Journal of neurochemistry, 2009, Volume: 111, Issue:6 Topics: Analgesics; Animals; Animals, Newborn; Arachidonic Acids; Astrocytes; Benzoxazines; Cannabinoids; Cells, Cultured; Cerebral Cortex; Connexin 43; Connexins; Culture Media, Conditioned; Cyclohexanols; Drug Interactions; Enzyme-Linked Immunosorbent Assay; Ethidium; Gene Expression Regulation; Interleukin-1beta; Lipopolysaccharides; Maximum Tolerated Dose; Mice; Microglia; Morpholines; Naphthalenes; Piperidines; Pyrazoles; Rimonabant; Tumor Necrosis Factor-alpha	2009
Dissimilar cannabinoid substitution patterns in mice trained to discriminate Δ(9)-tetrahydrocannabinol or methanandamide from vehicle. Behavioural pharmacology, 2011, Volume: 22, Issue:5-6 Topics: Animals; Arachidonic Acids; Cyclohexanols; Discrimination Learning; Dose-Response Relationship, Drug; Dronabinol; Female; Generalization, Stimulus; Male; Mice; Mice, Inbred C57BL; Piperidines; Psychotropic Drugs; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; Sex Factors	2011
Effects of cannabinoid agonists on sheep sphincter of oddi in vitro. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2011, Volume: 11, Issue:4 Topics: Analgesics; Animals; Arachidonic Acids; Benzoxazines; Camphanes; Cannabinoid Receptor Agonists; Cannabinoids; Carbachol; Cyclic GMP; Male; Morpholines; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Naphthalenes; NG-Nitroarginine Methyl Ester; Organ Culture Techniques; Piperidines; Pyrazoles; Rimonabant; Sheep; Sphincter of Oddi	2011
Differentiation between low- and high-efficacy CB1 receptor agonists using a drug discrimination protocol for rats. Psychopharmacology, 2014, Volume: 231, Issue:3 Topics: Animals; Arachidonic Acids; Benzoxazines; Cyclic AMP; Cyclohexanols; Discrimination, Psychological; Dose-Response Relationship, Drug; Dronabinol; Indoles; Isomerism; Male; Molecular Structure; Morpholines; Naphthalenes; Piperidines; Pyrazoles; Random Allocation; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Rimonabant	2014
Proapoptotic effect of endocannabinoids in prostate cancer cells. Oncology reports, 2015, Volume: 33, Issue:4 Topics: Adenocarcinoma; Apoptosis; Arachidonic Acids; Cell Cycle; Drug Screening Assays, Antitumor; Endocannabinoids; Glycerides; Humans; Male; MAP Kinase Signaling System; Neoplasm Proteins; Piperidines; Polyunsaturated Alkamides; Prostatic Hyperplasia; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Signal Transduction; Tumor Cells, Cultured	2015