Page last updated: 2024-08-26

sr141716 and 1,1-dimethylheptyl-11-hydroxytetrahydrocannabinol

sr141716 has been researched along with 1,1-dimethylheptyl-11-hydroxytetrahydrocannabinol in 64 studies

Research

Studies (64)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (10.94)18.2507
2000's47 (73.44)29.6817
2010's9 (14.06)24.3611
2020's1 (1.56)2.80

Authors

AuthorsStudies
Lambert, DM; Martin, D; Muccioli, GG; Poppitz, W; Poupaert, JH; Scriba, GK; Wouters, J1
Lambert, DM; Muccioli, GG; Poppitz, W; Poupaert, JH; Scriba, GK; Wouters, J1
Guzmán, M; Sánchez, C; Velasco, G1
Carrera, MR; Koob, GF; Navarro, M; Rodríguez de Fonseca, F; Weiss, F1
Burkey, TH; Consroe, P; Ehlert, FJ; Hosohata, Y; Quock, RM; Roeske, WR; Yamamura, HI1
Baba, N; Ishima, Y; Kodaka, T; Kondo, S; Miyashita, T; Nakane, S; Seki, C; Sugiura, T; Suhara, Y; Takayama, H; Waku, K1
Busse, R; Fleming, I; Popp, R; Schermer, B1
Brown, S; Derleth, C; Hsieh, C; Mackie, K1
Bonner, TI; Buckley, NE; Compton, DR; Járai, Z; Kunos, G; Lake, KD; Martin, BR; Mezey, E; Razdan, RK; Varga, K; Wagner, JA; Zimmer, A; Zimmer, AM1
Denhardt, G; Smith, SR; Terminelli, C2
Chapman, V; Drew, LJ; Harris, J; Kendall, DA; Millns, PJ1
Acquas, E; Di Chiara, G; Marrocu, P; Pisanu, A1
Cheer, JF; Kendall, DA; Marsden, CA1
Cheer, JF; Kendall, DA; Marsden, CA; Mason, R2
Gerdeman, G; Lovinger, DM1
Davydova, YG; Maimeskulova, LA; Mechoulam, R; Ugdyzhekova, DS1
Chapman, V; Kendall, DA; Millns, PJ1
Clarke, RW; Harris, J; Jenkins, S; Witton, SK1
Fox, A; Gentry, C; James, I; Kesingland, A; McNair, K; Patel, S; Urban, L1
Kendall, DA; Ralevic, V1
Bátkai, S; Járai, Z; Kunos, G; Wagner, JA1
Piomelli, D1
Crombag, H; De Vries, TJ; Dieben, J; Homberg, JR; Schoffelmeer, AN; Schuurman, K; Shaham, Y; Vanderschuren, LJ1
Guaza, C; Molina-Holgado, E; Molina-Holgado, F; Rothwell, NJ1
Gessa, GL; Muntoni, AL; Pillolla, G; Pistis, M1
Bernatskaia, NA; Krylatov, AV; Maslov, LN; Mechoulam, R; Pertwee, RG; Sal'nikova, OM; Sharaevskiĭ, MA; Stefano, GB1
Egan, RW; Hey, JA; Jia, Y; McLeod, RL; Parra, LE; Wang, X1
Breivogel, CS; Crim, JL; Darmani, NA; Janoyan, JJ; Martin, BR; Parekh, B; Sim-Selley, LJ1
Carai, MA; Casu, MA; Gessa, GL; Marchese, G; Pani, L; Porcella, A; Reali, R; Ruiu, S; Saba, P1
Abbott, L; Burton, P; Fudge, ML; Mechoulam, R; Parker, LA; Schlievert, C1
Harvey-White, J; Kunos, G; Liu, J; Wang, L; Zimmer, A1
Beckett, SR; Chapman, V; Finn, DP; Jhaveri, MD; Kendall, DA; Marsden, CA; Roe, CH1
Caberlotto, L; Eriksson, S; Hansson, A; Heilig, M; Rimondini, R1
Beckett, SR; Chapman, V; Finn, DP; Jhaveri, MD; Kendall, DA; Marsden, CA1
Cannich, A; Cravatt, BF; Ferri, GL; Hermann, H; Lutz, B; Marsicano, G; Massa, F; Monory, K; Sibaev, A; Storr, M1
Bátkai, S; Bukoski, RD; Harvey-White, J; Kunos, G; Liu, J; Mackie, K; Offertáler, L; Osei-Hyiaman, D; Pacher, P; Radaeva, S; Rudd, MA1
Nomikos, GG; Panagis, G; Vlachou, S1
Bannon, AW; Cravatt, BF; Depetrillo, M; Harvey-White, J; Kuhar, MJ; Kunos, G; Mackie, K; Osei-Hyiaman, D; Palkovits, M1
Krylatov, AV; Lasukova, OV; Maslov, LN; Pertwee, RG1
Argiolas, A; Castelli, MP; Mascia, MS; Melis, MR; Melis, T; Sanna, F; Succu, S1
Hille, B; Lauckner, JE; Mackie, K1
Bertolini, A; Ferrari, A; Leone, S; Ottani, A; Sandrini, M1
Adami, M; Bertini, S; Coruzzi, G; Giovannini, E; Guaita, E; Menozzi, A; Soldani, G1
Ahn, KH; D'Antona, AM; Kendall, DA1
De Vries, TJ; Hogenboom, F; Schoffelmeer, AN; Wardeh, G1
Diamond, M; Finn, DP; Kelly, JP; Roche, M1
Costentin, J; Duterte-Boucher, D; Hagues, G2
Arévalo-Martín, A; García-Ovejero, D; Gómez-Torres, O; Molina-Holgado, E; Molina-Holgado, F; Moore, JD; Rubio-Araiz, A; Williams, RJ1
Battista, N; Bernardi, G; Centonze, D; De Chiara, V; Maccarrone, M; Mercuri, NB; Prosperetti, C; Rossi, S; Usiello, A1
Crowford, D; Hanus, LO; Ivanchuk, II; Krylatov, AV; Lasukova, OV; Maslov, LN; Pertwee, R1
Goonawardena, AV; Hampson, RE; Pertwee, RG; Riedel, G; Robinson, L1
Haskó, G; Liaudet, L; Mackie, K; Mukhopadhyay, P; Pacher, P; Rajesh, M1
Dragunow, M; Glass, M; Goodfellow, CE; Graham, ES; Scotter, EL1
Bäckhed, F; Cani, PD; Delzenne, NM; Lambert, DM; Muccioli, GG; Naslain, D; Reigstad, CS1
Dowd, E; Finn, DP; Gorman, AM; Walsh, S1
Ai, R; Chang, CE1
Hruba, L; McMahon, LR1
Christopoulos, A; Glass, M; Khajehali, E; Leach, K; Malone, DT; Sexton, PM1
Abbas, MA; Aldaoud, N; Aldossary, SA; Alsalem, M; Altarifi, A; El-Salem, K; Haddad, M; Jaffal, SM; Kalbouneh, H1
Stavreva, GT; Tashev, RE; Velikova, MS1
Bilbao, A; Ferrer, B; Granado, N; Moratalla, R; Pavon, FJ; Rodríguez de Fonseca, F; Serrano, A; Suárez, J; Vadas, E1

Other Studies

64 other study(ies) available for sr141716 and 1,1-dimethylheptyl-11-hydroxytetrahydrocannabinol

ArticleYear
Substituted 5,5'-diphenyl-2-thioxoimidazolidin-4-one as CB1 cannabinoid receptor ligands: synthesis and pharmacological evaluation.
    Journal of medicinal chemistry, 2005, Apr-07, Volume: 48, Issue:7

    Topics: Animals; Binding, Competitive; CHO Cells; Cricetinae; Cricetulus; Humans; Imidazolidines; Ligands; Models, Molecular; Radioligand Assay; Receptor, Cannabinoid, CB1; Structure-Activity Relationship; Thiohydantoins

2005
1-Benzhydryl-3-phenylurea and 1-benzhydryl-3-phenylthiourea derivatives: new templates among the CB1 cannabinoid receptor inverse agonists.
    Journal of medicinal chemistry, 2005, Nov-17, Volume: 48, Issue:23

    Topics: Animals; Benzhydryl Compounds; Binding, Competitive; CHO Cells; Cricetinae; Cricetulus; Humans; Phenylthiourea; Phenylurea Compounds; Radioligand Assay; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Structure-Activity Relationship

2005
Metabolic stimulation of mouse spleen lymphocytes by low doses of delta9-tetrahydrocannabinol.
    Life sciences, 1997, Volume: 60, Issue:19

    Topics: Animals; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Dronabinol; Female; Glucose; In Vitro Techniques; Lymphocytes; Mice; Mice, Inbred BALB C; Oxidation-Reduction; Pertussis Toxin; Phospholipids; Piperidines; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Spleen; Virulence Factors, Bordetella

1997
Activation of corticotropin-releasing factor in the limbic system during cannabinoid withdrawal.
    Science (New York, N.Y.), 1997, Jun-27, Volume: 276, Issue:5321

    Topics: Amygdala; Animals; Anxiety; Behavior, Animal; Brain; Corticosterone; Corticotropin-Releasing Hormone; Dronabinol; Male; Microdialysis; Piperidines; Proto-Oncogene Proteins c-fos; Pyrazoles; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Substance Withdrawal Syndrome

1997
Relative efficacies of cannabinoid CB1 receptor agonists in the mouse brain.
    European journal of pharmacology, 1997, Oct-08, Volume: 336, Issue:2-3

    Topics: Animals; Arachidonic Acids; Brain; Cannabinoids; Cells, Cultured; Cyclohexanols; Dronabinol; Endocannabinoids; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Male; Mice; Mice, Inbred ICR; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant

1997
Evidence that the cannabinoid CB1 receptor is a 2-arachidonoylglycerol receptor. Structure-activity relationship of 2-arachidonoylglycerol, ether-linked analogues, and related compounds.
    The Journal of biological chemistry, 1999, Jan-29, Volume: 274, Issue:5

    Topics: Animals; Arachidonic Acids; Benzoxazines; Cannabinoids; Cell Line; Cyclohexanols; Dronabinol; Endocannabinoids; Models, Chemical; Morpholines; Naphthalenes; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Structure-Activity Relationship

1999
Inhibition of the production of endothelium-derived hyperpolarizing factor by cannabinoid receptor agonists.
    British journal of pharmacology, 1999, Volume: 126, Issue:4

    Topics: Animals; Arachidonic Acids; Biological Factors; Calcium; Cells, Cultured; Cyclic AMP; Cytochrome P-450 Enzyme System; Dronabinol; Endocannabinoids; Female; Male; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rabbits; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Swine; Vasoconstriction

1999
Internalization and recycling of the CB1 cannabinoid receptor.
    Journal of neurochemistry, 1999, Volume: 73, Issue:2

    Topics: Acids; Ammonium Chloride; Animals; Arachidonic Acids; Benzoxazines; Calcium Channel Blockers; Cannabinoids; Cells, Cultured; Clathrin; Coated Vesicles; Cyclohexanols; Dronabinol; Drug Tolerance; Endocytosis; Endosomes; Excitatory Amino Acid Antagonists; GTP-Binding Proteins; Immunosuppressive Agents; Morpholines; Mutagenesis; Naphthalenes; Phosphorylation; Piperidines; Protein Binding; Protein Structure, Tertiary; Pyrazoles; Rats; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Transfection; Up-Regulation; Virulence Factors, Bordetella

1999
Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, Nov-23, Volume: 96, Issue:24

    Topics: Animals; Arachidonic Acids; Cannabidiol; Cannabinoids; Dronabinol; Endocannabinoids; Endothelium, Vascular; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Nitric Oxide; Piperidines; Polyunsaturated Alkamides; Potassium Channels; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Vasodilation; Vasodilator Agents

1999
Effects of cannabinoid receptor agonist and antagonist ligands on production of inflammatory cytokines and anti-inflammatory interleukin-10 in endotoxemic mice.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 293, Issue:1

    Topics: Animals; Benzoxazines; Camphanes; Cannabinoids; Cytokines; Dronabinol; Endotoxemia; Endotoxins; Interleukin-10; Interleukin-12; Interleukin-2; Ligands; Lipopolysaccharides; Male; Mice; Morpholines; Naphthalenes; Piperidines; Propionibacterium acnes; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Tumor Necrosis Factor-alpha

2000
Activation of spinal cannabinoid 1 receptors inhibits C-fibre driven hyperexcitable neuronal responses and increases [35S]GTPgammaS binding in the dorsal horn of the spinal cord of noninflamed and inflamed rats.
    The European journal of neuroscience, 2000, Volume: 12, Issue:6

    Topics: Animals; Binding, Competitive; Cannabinoids; Carrageenan; Dronabinol; Electrophysiology; Guanosine 5'-O-(3-Thiotriphosphate); Myelitis; Nerve Fibers; Nociceptors; Piperidines; Posterior Horn Cells; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Sulfur Radioisotopes

2000
Cannabinoid CB(1) receptor agonists increase rat cortical and hippocampal acetylcholine release in vivo.
    European journal of pharmacology, 2000, Aug-04, Volume: 401, Issue:2

    Topics: Acetylcholine; Animals; Behavior, Animal; Benzoxazines; Dose-Response Relationship, Drug; Dronabinol; Hippocampus; Male; Microdialysis; Morpholines; Naphthalenes; Piperidines; Prefrontal Cortex; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Receptors, Drug; Rimonabant

2000
Cannabinoid receptors and reward in the rat: a conditioned place preference study.
    Psychopharmacology, 2000, Volume: 151, Issue:1

    Topics: Animals; Avoidance Learning; Cannabinoids; Conditioning, Psychological; Dronabinol; Male; Piperidines; Pyrazoles; Rats; Receptors, Cannabinoid; Receptors, Drug; Reward; Rimonabant; Substance Withdrawal Syndrome

2000
Lack of response suppression follows repeated ventral tegmental cannabinoid administration: an in vitro electrophysiological study.
    Neuroscience, 2000, Volume: 99, Issue:4

    Topics: Action Potentials; Animals; Bicuculline; Cannabinoids; Dopamine; Dronabinol; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Interneurons; Male; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Reward; Rimonabant; Ventral Tegmental Area

2000
CB1 cannabinoid receptor inhibits synaptic release of glutamate in rat dorsolateral striatum.
    Journal of neurophysiology, 2001, Volume: 85, Issue:1

    Topics: Animals; Benzoxazines; Calcium; Cannabinoids; Corpus Striatum; Dronabinol; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Morpholines; Naphthalenes; Patch-Clamp Techniques; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Strontium; Synapses; Synaptic Transmission

2001
Involvement of central and peripheral cannabinoid receptors in the regulation of heart resistance to arrhythmogenic effects of epinephrine.
    Bulletin of experimental biology and medicine, 2000, Volume: 130, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; Cannabinoids; Disease Models, Animal; Dronabinol; Epinephrine; Ganglionic Blockers; Heart; Hexamethonium; Immunity, Innate; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Drug; Rimonabant

2000
Cannabinoid inhibition of the capsaicin-induced calcium response in rat dorsal root ganglion neurones.
    British journal of pharmacology, 2001, Volume: 132, Issue:5

    Topics: Animals; Calcium; Cannabinoids; Capsaicin; Dronabinol; Ganglia, Spinal; Neurons; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Drug; Rimonabant

2001
Cannabinoidergic and opioidergic inhibition of spinal reflexes in the decerebrated, spinalized rabbit.
    Neuropharmacology, 2001, Volume: 40, Issue:4

    Topics: Animals; Decerebrate State; Dose-Response Relationship, Drug; Dronabinol; Female; Fentanyl; Male; Naloxone; Narcotic Antagonists; Piperidines; Pyrazoles; Rabbits; Receptors, Cannabinoid; Receptors, Drug; Reflex; Rimonabant; Spinal Cord; Spinal Cord Injuries

2001
The role of central and peripheral Cannabinoid1 receptors in the antihyperalgesic activity of cannabinoids in a model of neuropathic pain.
    Pain, 2001, Volume: 92, Issue:1-2

    Topics: Analgesics; Animals; Benzoxazines; Cannabinoids; Cyclohexanols; Disease Models, Animal; Dronabinol; Hyperalgesia; Morpholines; Naphthalenes; Pain Measurement; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Sciatica

2001
Cannabinoid inhibition of capsaicin-sensitive sensory neurotransmission in the rat mesenteric arterial bed.
    European journal of pharmacology, 2001, Apr-20, Volume: 418, Issue:1-2

    Topics: Adenosine Diphosphate; Animals; Benzofurans; Calcitonin Gene-Related Peptide; Camphanes; Cannabinoids; Capsaicin; Dose-Response Relationship, Drug; Dronabinol; Electric Stimulation; Electrophysiology; Male; Mesenteric Arteries; Neurons, Afferent; Nitroprusside; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Synaptic Transmission; Time Factors; Vasodilation; Vasodilator Agents

2001
Hemodynamic effects of cannabinoids: coronary and cerebral vasodilation mediated by cannabinoid CB(1) receptors.
    European journal of pharmacology, 2001, Jul-06, Volume: 423, Issue:2-3

    Topics: Animals; Arachidonic Acids; Blood Pressure; Brain; Cannabinoids; Coronary Circulation; Coronary Vessels; Dronabinol; Endocannabinoids; Heart Rate; Hemodynamics; Male; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Vascular Resistance; Vasodilation

2001
Cannabinoid activity curtails cocaine craving.
    Nature medicine, 2001, Volume: 7, Issue:10

    Topics: Animals; Cannabinoids; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dronabinol; Humans; Piperidines; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant

2001
A cannabinoid mechanism in relapse to cocaine seeking.
    Nature medicine, 2001, Volume: 7, Issue:10

    Topics: Animals; Behavior, Animal; Cannabinoid Receptor Modulators; Cannabinoids; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dronabinol; Humans; Piperidines; Pyrazoles; Rats; Rats, Long-Evans; Rats, Wistar; Receptors, Cannabinoid; Receptors, Drug; Recurrence; Rimonabant

2001
Modulation of cytokine responses in Corynebacterium parvum-primed endotoxemic mice by centrally administered cannabinoid ligands.
    European journal of pharmacology, 2001, Aug-03, Volume: 425, Issue:1

    Topics: Animals; Benzoxazines; Camphanes; Cannabinoids; Cytokines; Dose-Response Relationship, Drug; Dronabinol; Endotoxemia; Endotoxins; Injections, Intraperitoneal; Injections, Intravenous; Injections, Intraventricular; Interleukin-10; Interleukin-12; Ligands; Male; Mice; Mice, Knockout; Morpholines; Naphthalenes; Piperidines; Propionibacterium acnes; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Survival Rate; Tumor Necrosis Factor-alpha; Virulence Factors, Bordetella

2001
Role of CB1 and CB2 receptors in the inhibitory effects of cannabinoids on lipopolysaccharide-induced nitric oxide release in astrocyte cultures.
    Journal of neuroscience research, 2002, Mar-15, Volume: 67, Issue:6

    Topics: Analgesics; Animals; Arachidonic Acids; Astrocytes; Calcium Channel Blockers; Camphanes; Cannabinoids; Cells, Cultured; Cyclohexanols; Dronabinol; Endocannabinoids; Gene Expression; Lipopolysaccharides; Mice; Mice, Inbred Strains; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant

2002
Cannabinoids inhibit excitatory inputs to neurons in the shell of the nucleus accumbens: an in vivo electrophysiological study.
    The European journal of neuroscience, 2002, Volume: 15, Issue:11

    Topics: Action Potentials; Amygdala; Analgesics; Animals; Benzoxazines; Cannabinoids; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Dronabinol; Electric Stimulation; Glutamic Acid; Male; Morpholines; Naphthalenes; Narcotic Antagonists; Neural Inhibition; Neural Pathways; Nucleus Accumbens; Piperidines; Prefrontal Cortex; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Synaptic Transmission

2002
[Increase of the heart arrhythmogenic resistance and decrease of the myocardial necrosis zone during activation of cannabinoid receptors].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2002, Volume: 88, Issue:5

    Topics: Aconitine; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Arterial Occlusive Diseases; Camphanes; Cannabinoids; Coronary Artery Disease; Dronabinol; Epinephrine; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Drug; Rimonabant

2002
Anandamide induces cough in conscious guinea-pigs through VR1 receptors.
    British journal of pharmacology, 2002, Volume: 137, Issue:6

    Topics: Aerosols; Animals; Arachidonic Acids; Calcium; Camphanes; Capsaicin; Cells, Cultured; Consciousness; Cough; Dronabinol; Endocannabinoids; Excitatory Amino Acid Antagonists; Guinea Pigs; Male; Nodose Ganglion; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant

2002
Antiemetic and motor-depressive actions of CP55,940: cannabinoid CB1 receptor characterization, distribution, and G-protein activation.
    European journal of pharmacology, 2003, Jan-10, Volume: 459, Issue:1

    Topics: Animals; Antiemetics; Benzoxazines; Binding, Competitive; Brain; Cisplatin; Cyclohexanols; Dose-Response Relationship, Drug; Dronabinol; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Injections, Intraperitoneal; Injections, Subcutaneous; Male; Morpholines; Motor Activity; Naphthalenes; Piperidines; Pyrazoles; Radioligand Assay; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Shrews; Sulfur Radioisotopes; Tritium; Vomiting

2003
Differential distribution of functional cannabinoid CB1 receptors in the mouse gastroenteric tract.
    European journal of pharmacology, 2003, Jan-10, Volume: 459, Issue:1

    Topics: Animals; Antiemetics; Binding, Competitive; Blotting, Western; Cyclohexanols; Digestive System; Dose-Response Relationship, Drug; Dronabinol; Gastric Mucosa; Gastrointestinal Transit; Immunohistochemistry; Intestine, Large; Intestine, Small; Male; Mice; Piperidines; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Stomach; Tritium

2003
Effects of cannabinoids on lithium-induced conditioned rejection reactions in a rat model of nausea.
    Psychopharmacology, 2003, Volume: 166, Issue:2

    Topics: Animals; Antiemetics; Avoidance Learning; Behavior, Animal; Cannabinoids; Conditioning, Psychological; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Lithium; Male; Nausea; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Rimonabant

2003
Endocannabinoid signaling via cannabinoid receptor 1 is involved in ethanol preference and its age-dependent decline in mice.
    Proceedings of the National Academy of Sciences of the United States of America, 2003, Feb-04, Volume: 100, Issue:3

    Topics: Aging; Alcohol Drinking; Animals; Blotting, Western; Brain; Cannabinoid Receptor Modulators; Cannabinoids; Dose-Response Relationship, Drug; Dronabinol; Endocannabinoids; Ethanol; Fatty Acids, Unsaturated; Feeding Behavior; Guanosine 5'-O-(3-Thiotriphosphate); Mice; Mice, Inbred C57BL; Mice, Transgenic; Pertussis Toxin; Piperidines; Protein Binding; Pyrazoles; Radioligand Assay; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Signal Transduction; Tissue Distribution

2003
Differential cannabinoid-induced electrophysiological effects in rat ventral tegmentum.
    Neuropharmacology, 2003, Volume: 44, Issue:5

    Topics: Action Potentials; Animals; Cannabinoids; Dronabinol; Electrophysiology; Male; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Ventral Tegmental Area

2003
Effects of direct periaqueductal grey administration of a cannabinoid receptor agonist on nociceptive and aversive responses in rats.
    Neuropharmacology, 2003, Volume: 45, Issue:5

    Topics: Analysis of Variance; Animals; Behavior, Animal; Cannabinoid Receptor Agonists; Disinfectants; Dose-Response Relationship, Drug; Dronabinol; Drug Combinations; Escape Reaction; Excitatory Amino Acid Antagonists; Formaldehyde; Homocysteine; Immunohistochemistry; Male; Microinjections; Movement; Pain; Pain Measurement; Periaqueductal Gray; Piperidines; Proto-Oncogene Proteins c-fos; Pyrazoles; Rats; Rats, Sprague-Dawley; Rimonabant; Time Factors

2003
Corticotropin-releasing hormone (CRH) mRNA expression in rat central amygdala in cannabinoid tolerance and withdrawal: evidence for an allostatic shift?
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2004, Volume: 29, Issue:1

    Topics: Amygdala; Analysis of Variance; Animals; Behavior, Animal; Cannabinoids; Corticotropin-Releasing Hormone; Dose-Response Relationship, Drug; Dronabinol; Drug Administration Schedule; Drug Tolerance; Excitatory Amino Acid Antagonists; Gene Expression Regulation; In Situ Hybridization; Locomotion; Male; Maze Learning; Neostriatum; Neuropeptide Y; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptors, Neuropeptide Y; Rimonabant; RNA, Messenger; Substance Withdrawal Syndrome; Time Factors

2004
Cannabinoids modulate ultrasound-induced aversive responses in rats.
    Psychopharmacology, 2004, Volume: 172, Issue:1

    Topics: Animals; Behavior, Animal; Corticosterone; Dronabinol; Male; Panic; Periaqueductal Gray; Piperidines; Pyrazoles; Rats; Receptor, Cannabinoid, CB1; Rimonabant; Ultrasonics

2004
The endogenous cannabinoid system protects against colonic inflammation.
    The Journal of clinical investigation, 2004, Volume: 113, Issue:8

    Topics: Amidohydrolases; Animals; Colitis; Dinitrofluorobenzene; Dronabinol; Female; Gene Expression Regulation; Mice; Mice, Inbred C57BL; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; RNA, Messenger

2004
Endocannabinoids acting at cannabinoid-1 receptors regulate cardiovascular function in hypertension.
    Circulation, 2004, Oct-05, Volume: 110, Issue:14

    Topics: Amidohydrolases; Angiotensin II; Animals; Arachidonic Acids; Benzamides; Benzyl Compounds; Blood Pressure; Camphanes; Carbamates; Dronabinol; Endocannabinoids; Endothelium, Vascular; Hypertension; Male; Models, Cardiovascular; Myocardial Contraction; Myocardium; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Inbred Dahl; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Rimonabant; Up-Regulation; Vascular Resistance; Vasodilation; Ventricular Function, Left

2004
CB1 cannabinoid receptor agonists increase intracranial self-stimulation thresholds in the rat.
    Psychopharmacology, 2005, Volume: 179, Issue:2

    Topics: Animals; Benzoxazines; Brain; Dronabinol; Electrodes, Implanted; Male; Morpholines; Naphthalenes; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Reward; Rimonabant; Self Stimulation

2005
Cocaine- and amphetamine-related transcript is involved in the orexigenic effect of endogenous anandamide.
    Neuroendocrinology, 2005, Volume: 81, Issue:4

    Topics: Animals; Appetite; Arachidonic Acids; Brain; Brain Chemistry; Cannabinoid Receptor Modulators; Dronabinol; Eating; Endocannabinoids; Food Deprivation; Immunohistochemistry; Mice; Mice, Knockout; Nerve Endings; Nerve Fibers; Nerve Tissue Proteins; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant

2005
Cannabinoid receptor antagonists SR141716 and SR144528 exhibit properties of partial agonists in experiments on isolated perfused rat heart.
    Bulletin of experimental biology and medicine, 2005, Volume: 139, Issue:5

    Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Camphanes; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Cannabinoids; Dronabinol; Heart; Heart Rate; In Vitro Techniques; Myocardial Contraction; Piperidines; Pyrazoles; Rats; Receptors, Cannabinoid; Rimonabant

2005
The cannabinoid receptor antagonist SR-141716A induces penile erection in male rats: involvement of paraventricular glutamic acid and nitric oxide.
    Neuropharmacology, 2006, Volume: 50, Issue:2

    Topics: Animals; Behavior, Animal; Benzoxazines; Cannabinoid Receptor Antagonists; Dose-Response Relationship, Drug; Dronabinol; Enzyme Inhibitors; Excitatory Amino Acid Agonists; GABA Agonists; Glutamic Acid; Injections, Intraventricular; Male; Microdialysis; Microinjections; Morpholines; Naphthalenes; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Oxytocin; Paraventricular Hypothalamic Nucleus; Penile Erection; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Rimonabant

2006
The cannabinoid agonist WIN55,212-2 increases intracellular calcium via CB1 receptor coupling to Gq/11 G proteins.
    Proceedings of the National Academy of Sciences of the United States of America, 2005, Dec-27, Volume: 102, Issue:52

    Topics: Analgesics; Animals; Arachidonic Acids; Benzoxazines; Calcium; Cannabinoids; Cell Line; Cyclohexanols; Cytoplasm; DNA, Complementary; Dronabinol; Endocannabinoids; Endoplasmic Reticulum; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Fura-2; Glycerides; GTP-Binding Protein alpha Subunits, Gq-G11; Hippocampus; Humans; Immunosuppressive Agents; Morpholines; Naphthalenes; Neurons; Pertussis Toxin; Piperidines; Protein Binding; Protein Conformation; Pyrazoles; Rats; Receptor, Cannabinoid, CB1; Rimonabant; Ryanodine; Time Factors; Type C Phospholipases

2005
The analgesic activity of paracetamol is prevented by the blockade of cannabinoid CB1 receptors.
    European journal of pharmacology, 2006, Feb-15, Volume: 531, Issue:1-3

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Dose-Response Relationship, Drug; Dronabinol; Male; Morpholines; Nociceptors; Pain Measurement; Pain Threshold; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Rimonabant

2006
Effects of cannabinoid receptor agonists on rat gastric acid secretion: discrepancy between in vitro and in vivo data.
    Digestive diseases and sciences, 2006, Volume: 51, Issue:2

    Topics: Age Factors; Animals; Benzoxazines; Dronabinol; Gastric Acid; Gastric Fundus; Gastric Mucosa; Ligands; Male; Morpholines; Naphthalenes; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Rimonabant; Tissue Culture Techniques

2006
Mutations of CB1 T210 produce active and inactive receptor forms: correlations with ligand affinity, receptor stability, and cellular localization.
    Biochemistry, 2006, May-02, Volume: 45, Issue:17

    Topics: Amino Acid Sequence; Amino Acid Substitution; Arachidonic Acids; Benzoxazines; Cells, Cultured; Cyclic AMP; Dronabinol; Drug Stability; Guanosine 5'-O-(3-Thiotriphosphate); Hot Temperature; Humans; Kidney; Ligands; Morpholines; Mutation; Naphthalenes; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; Threonine

2006
Interactions between CB1 cannabinoid and mu opioid receptors mediating inhibition of neurotransmitter release in rat nucleus accumbens core.
    Neuropharmacology, 2006, Volume: 51, Issue:4

    Topics: Animals; Calcium; Dose-Response Relationship, Drug; Dronabinol; Drug Interactions; Excitatory Amino Acid Antagonists; Male; Morphine; Naloxone; Narcotic Antagonists; Neural Inhibition; Neurotransmitter Agents; Nucleus Accumbens; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptors, Opioid, mu; Rimonabant; Tritium

2006
In vivo modulation of LPS-induced alterations in brain and peripheral cytokines and HPA axis activity by cannabinoids.
    Journal of neuroimmunology, 2006, Volume: 181, Issue:1-2

    Topics: Animals; Camphanes; Corticosterone; Dronabinol; Drug Interactions; Encephalitis; Hypothalamo-Hypophyseal System; Interferon-gamma; Interleukin-10; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Lymphocyte Count; Male; Neuroimmunomodulation; Neuroprotective Agents; Piperidines; Pituitary-Adrenal System; Pyrazoles; Rats; Rats, Sprague-Dawley; Rimonabant; Tumor Necrosis Factor-alpha

2006
Modulation of morphine and alcohol motor stimulant effects by cannabinoid receptors ligands.
    Behavioural brain research, 2007, Mar-28, Volume: 178, Issue:2

    Topics: Analysis of Variance; Animals; Cannabinoid Receptor Antagonists; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Dronabinol; Drug Antagonism; Ethanol; Ligands; Mice; Morphine; Motor Activity; Piperidines; Pyrazoles; Receptors, Cannabinoid; Rimonabant; Statistics, Nonparametric

2007
CB2 cannabinoid receptors promote mouse neural stem cell proliferation.
    The European journal of neuroscience, 2007, Volume: 25, Issue:3

    Topics: Animals; Arachidonic Acids; Camphanes; Cell Division; Cells, Cultured; Cerebral Cortex; Dronabinol; Excitatory Amino Acid Antagonists; Lipoprotein Lipase; Mice; Neurons; Phosphatidylinositol 3-Kinases; Piperidines; Proto-Oncogene Proteins c-akt; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Signal Transduction; Spheroids, Cellular; Stem Cells

2007
Chronic cocaine sensitizes striatal GABAergic synapses to the stimulation of cannabinoid CB1 receptors.
    The European journal of neuroscience, 2007, Volume: 25, Issue:6

    Topics: Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Corpus Striatum; Dopamine Uptake Inhibitors; Dronabinol; Drug Administration Schedule; Drug Interactions; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamic Acid; Male; Patch-Clamp Techniques; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Rimonabant; Synapses

2007
Role of cannabinoid receptors in the regulation of cardiac contractility during ischemia/reperfusion.
    Bulletin of experimental biology and medicine, 2006, Volume: 142, Issue:5

    Topics: Animals; Blood Pressure; Camphanes; Dronabinol; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Myocardial Reperfusion Injury; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptors, Cannabinoid; Rimonabant

2006
The synthetic cannabinoid HU210 induces spatial memory deficits and suppresses hippocampal firing rate in rats.
    British journal of pharmacology, 2007, Volume: 151, Issue:5

    Topics: Animals; Behavior, Animal; Cannabinoids; Dronabinol; Electrophysiology; Hippocampus; Male; Maze Learning; Memory; Memory Disorders; Morpholines; Motor Activity; Neurons; Piperidines; Pyrazoles; Rats; Receptor, Cannabinoid, CB1; Rimonabant; Space Perception

2007
Locomotor effects of morphine or alcohol in mice after a repeated treatment with the cannabinoid agonist HU 210.
    European journal of pharmacology, 2008, May-31, Volume: 586, Issue:1-3

    Topics: Analgesics, Opioid; Animals; Cannabinoid Receptor Agonists; Central Nervous System Depressants; Dose-Response Relationship, Drug; Dronabinol; Ethanol; Male; Mice; Morphine; Motor Activity; Piperidines; Pyrazoles; Rimonabant

2008
Cannabinoid-1 receptor activation induces reactive oxygen species-dependent and -independent mitogen-activated protein kinase activation and cell death in human coronary artery endothelial cells.
    British journal of pharmacology, 2010, Volume: 160, Issue:3

    Topics: Acetylcysteine; Arachidonic Acids; Cell Death; Cell Line; Coronary Vessels; Dose-Response Relationship, Drug; Dronabinol; Endocannabinoids; Endothelial Cells; Humans; Mitogen-Activated Protein Kinases; Morpholines; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Reactive Oxygen Species; Receptor, Cannabinoid, CB1; Rimonabant; Signal Transduction

2010
Neuroprotective potential of CB1 receptor agonists in an in vitro model of Huntington's disease.
    British journal of pharmacology, 2010, Volume: 160, Issue:3

    Topics: Animals; Butadienes; Cell Culture Techniques; Cell Death; Cell Line, Transformed; Cerebellum; Cyclic AMP; Dronabinol; GTP-Binding Protein alpha Subunits; Humans; Huntingtin Protein; Huntington Disease; Mice; Mitogen-Activated Protein Kinase 3; Nerve Tissue Proteins; Neuroprotective Agents; Nitriles; Nuclear Proteins; PC12 Cells; Pertussis Toxin; Piperidines; Pyrazoles; Rats; Receptor, Cannabinoid, CB1; Receptors, Dopamine; Rimonabant

2010
The endocannabinoid system links gut microbiota to adipogenesis.
    Molecular systems biology, 2010, Volume: 6

    Topics: Adipogenesis; Adipose Tissue; Animals; Arachidonic Acids; Bacterial Translocation; Caco-2 Cells; Cannabinoid Receptor Modulators; Disease Models, Animal; Dronabinol; Endocannabinoids; Glycerides; Humans; Intestinal Mucosa; Intestines; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Myeloid Differentiation Factor 88; Obesity; Permeability; Piperidines; Polyunsaturated Alkamides; Prebiotics; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; RNA, Messenger

2010
The effects of cannabinoid drugs on abnormal involuntary movements in dyskinetic and non-dyskinetic 6-hydroxydopamine lesioned rats.
    Brain research, 2010, Dec-02, Volume: 1363

    Topics: Animals; Antiparkinson Agents; Disease Models, Animal; Dronabinol; Dyskinesia, Drug-Induced; Levodopa; Male; Parkinsonian Disorders; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Rimonabant

2010
Ligand-specific homology modeling of human cannabinoid (CB1) receptor.
    Journal of molecular graphics & modelling, 2012, Volume: 38

    Topics: Amino Acid Sequence; Arachidonic Acids; Benzoxazines; Binding Sites; Dronabinol; Humans; Ligands; Molecular Docking Simulation; Molecular Sequence Data; Morpholines; Naphthalenes; Piperidines; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Pyrazoles; Receptor, Cannabinoid, CB1; Receptors, Adenosine A2; Receptors, Adrenergic, beta-2; Rhodopsin; Rimonabant; Sequence Alignment; Structural Homology, Protein; Structure-Activity Relationship; Thermodynamics

2012
The cannabinoid agonist HU-210: pseudo-irreversible discriminative stimulus effects in rhesus monkeys.
    European journal of pharmacology, 2014, Mar-15, Volume: 727

    Topics: Animals; Behavior, Animal; Benzoxazines; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Cyclohexanols; Discrimination, Psychological; Dose-Response Relationship, Drug; Dronabinol; Female; Macaca mulatta; Male; Morpholines; Naphthalenes; Piperidines; Pyrazoles; Receptors, Cannabinoid; Rimonabant; Time Factors

2014
Biased Agonism and Biased Allosteric Modulation at the CB1 Cannabinoid Receptor.
    Molecular pharmacology, 2015, Volume: 88, Issue:2

    Topics: Allosteric Regulation; Animals; Benzoxazines; Cannabinoid Receptor Agonists; CHO Cells; Cricetulus; Cyclohexanols; Dronabinol; Humans; Indoles; MAP Kinase Signaling System; Morpholines; Naphthalenes; Phosphorylation; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; Signal Transduction

2015
Role of cannabinoid receptor 1 and the peroxisome proliferator-activated receptor α in mediating anti-nociceptive effects of synthetic cannabinoids and a cannabinoid-like compound.
    Inflammopharmacology, 2019, Volume: 27, Issue:6

    Topics: Amides; Analgesics; Animals; Cannabinoids; Dronabinol; Ethanolamines; Iodoacetic Acid; Male; Motor Activity; Osteoarthritis; Oxazoles; Palmitic Acids; PPAR alpha; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Rimonabant; Tyrosine

2019
Subchronic Central Administration of Cannabinoid Ligands Modulates Nociception in Bulbectomized Rats.
    Folia medica, 2019, 12-31, Volume: 61, Issue:4

    Topics: Animals; Depression; Disease Models, Animal; Dronabinol; Ligands; Male; Nociception; Olfactory Bulb; Pain Threshold; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Rimonabant

2019
Genetic deletion of dopamine D1 receptors increases the sensitivity to cannabinoid CB1 receptor antagonist-precipitated withdrawal when compared with wild-type littermates: studies in female mice repeatedly exposed to the Spice cannabinoid HU-210.
    Psychopharmacology, 2021, Volume: 238, Issue:2

    Topics: Animals; Behavior, Animal; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Dose-Response Relationship, Drug; Dronabinol; Female; Male; Mice; Mice, Knockout; Motor Activity; Receptor, Cannabinoid, CB1; Receptors, Dopamine D1; Receptors, Dopamine D2; Rimonabant; Substance Withdrawal Syndrome

2021