Compounds > sr141716
Page last updated: 2024-08-26

sr141716 and 1-(4-chlorophenyl)-3-(3-(6-pyrrolidin-1-ylpyridin-2-yl)phenyl)urea

sr141716 has been researched along with 1-(4-chlorophenyl)-3-(3-(6-pyrrolidin-1-ylpyridin-2-yl)phenyl)urea in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's3 (60.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Decker, AM; Gay, EA; German, N; Gilmour, BP; Thomas, BF; Wiley, JL; Zhang, Y1
Barrus, D; Decker, AM; Gamage, TF; Langston, TL; Li, JX; Nguyen, T; Thomas, BF; Zhang, Y1
Babbs, AJ; Bali, U; Horswill, JG; Jeevaratnam, P; Keily, JF; Reynet, C; Shaaban, S; Wong Kai In, P1
Farquhar, CE; Gamage, TF; Lefever, TW; Nguyen, T; Thomas, BF; Wiley, JL; Zhang, Y1
Dopart, R; Kendall, DA1

Other Studies

5 other study(ies) available for sr141716 and 1-(4-chlorophenyl)-3-(3-(6-pyrrolidin-1-ylpyridin-2-yl)phenyl)urea

ArticleYear
Diarylureas as allosteric modulators of the cannabinoid CB1 receptor: structure-activity relationship studies on 1-(4-chlorophenyl)-3-{3-[6-(pyrrolidin-1-yl)pyridin-2-yl]phenyl}urea (PSNCBAM-1).
    Journal of medicinal chemistry, 2014, Sep-25, Volume: 57, Issue:18

    Topics: Allosteric Regulation; Calcium; Cell Line; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; Phenylurea Compounds; Pyridines; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Structure-Activity Relationship

2014
Synthesis and Pharmacological Evaluation of 1-Phenyl-3-Thiophenylurea Derivatives as Cannabinoid Type-1 Receptor Allosteric Modulators.
    Journal of medicinal chemistry, 2019, 11-14, Volume: 62, Issue:21

    Topics: Allosteric Regulation; Chemistry Techniques, Synthetic; Cyclic AMP; HEK293 Cells; Humans; Phenylurea Compounds; Receptor, Cannabinoid, CB1; Structure-Activity Relationship

2019
PSNCBAM-1, a novel allosteric antagonist at cannabinoid CB1 receptors with hypophagic effects in rats.
    British journal of pharmacology, 2007, Volume: 152, Issue:5

    Topics: Allosteric Regulation; Animals; Appetite Depressants; Cell Line; Cell Membrane; Cerebral Cortex; Cyclic AMP; Cyclohexanols; Dose-Response Relationship, Drug; Eating; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Male; Molecular Structure; Phenylurea Compounds; Piperidines; Pyrazoles; Pyridines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Rimonabant; Saccharomyces cerevisiae; Silicone Elastomers; Sulfur Radioisotopes; Weight Gain

2007
The great divide: Separation between in vitro and in vivo effects of PSNCBAM-based CB
    Neuropharmacology, 2017, Volume: 125

    Topics: Allosteric Regulation; Animals; Cannabinoid Receptor Modulators; Cerebellum; Cyclohexanols; Discrimination, Psychological; Dose-Response Relationship, Drug; Dronabinol; Drug Interactions; Guanosine 5'-O-(3-Thiotriphosphate); Male; Mice, Inbred C57BL; Mice, Inbred ICR; Motor Activity; Phenylurea Compounds; Piperidines; Pregnenolone; Pyrazoles; Pyridines; Receptor, Cannabinoid, CB1; Rimonabant

2017
Allosteric modulators restore orthosteric agonist binding to mutated CB
    The Journal of pharmacy and pharmacology, 2020, Volume: 72, Issue:1

    Topics: Binding Sites; Cannabinoid Receptor Agonists; Cyclohexanols; HEK293 Cells; Humans; Indoles; Ligands; Mutation; Phenylurea Compounds; Piperidines; Protein Binding; Protein Conformation; Pyridines; Receptor, Cannabinoid, CB1; Rimonabant; Structure-Activity Relationship

2020