Page last updated: 2024-09-02

sr 95531 and furosemide

sr 95531 has been researched along with furosemide in 8 studies

Compound Research Comparison

Studies
(sr 95531)
Trials
(sr 95531)
Recent Studies (post-2010)
(sr 95531)
Studies
(furosemide)
Trials
(furosemide)
Recent Studies (post-2010) (furosemide)
610020913,6311,3582,486

Protein Interaction Comparison

ProteinTaxonomysr 95531 (IC50)furosemide (IC50)
Corticosteroid 11-beta-dehydrogenase isozyme 1Homo sapiens (human)3.76
Corticosteroid 11-beta-dehydrogenase isozyme 1Mus musculus (house mouse)3.76
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)3.2

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (37.50)18.2507
2000's4 (50.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Korpi, ER; Lüddens, H1
Firestone, LL; Homanics, GE; Korpi, ER; Mäkelä, R; Quinlan, JJ; Uusi-Oukari, M; Wisden, W1
Alho, H; Anghelescu, I; Klawe, C; Korpi, ER; Lüddens, H; Mäkelä, R; Oja, SS; Uusi-Oukari, M1
Wall, MJ1
Amin, J; Hadley, SH1
Heinrich, M; Milenković, I; Reinert, T; Rübsamen, R; Turecek, R; Witte, M1
Andresen, MC; Jin, YH; Mendelowitz, D; Zhang, Z1
Aguilar, J; Bautista, W; Delgado-Lezama, R; Loeza-Alcocer, JE1

Other Studies

8 other study(ies) available for sr 95531 and furosemide

ArticleYear
Furosemide interactions with brain GABAA receptors.
    British journal of pharmacology, 1997, Volume: 120, Issue:5

    Topics: Animals; Autoradiography; Brain; Cell Line; Clozapine; Diuretics; Furosemide; GABA Antagonists; Humans; Male; Pyridazines; Rats; Rats, Wistar; Receptors, GABA-A; Recombinant Proteins

1997
Cerebellar gamma-aminobutyric acid type A receptors: pharmacological subtypes revealed by mutant mouse lines.
    Molecular pharmacology, 1997, Volume: 52, Issue:3

    Topics: Animals; Azides; Benzodiazepines; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Carbolines; Cerebellum; Convulsants; Diazepam; Diuretics; Furosemide; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Mice; Mice, Inbred C57BL; Mutation; Pregnanolone; Pyridazines; Receptors, GABA-A; Sulfur Radioisotopes; Tritium; Zinc

1997
Furosemide action on cerebellar GABA(A) receptors in alcohol-sensitive ANT rats.
    Alcohol (Fayetteville, N.Y.), 1999, Volume: 19, Issue:3

    Topics: Alcoholism; Animals; Azides; Benzodiazepines; Bicuculline; Bridged Bicyclo Compounds, Heterocyclic; Carbolines; Cerebellum; Drug Combinations; Female; Furosemide; GABA Agonists; GABA Antagonists; Ligands; Male; Pyridazines; Rats; Receptors, GABA-A; Sodium Chloride

1999
Competitive GABA(A) receptor antagonists increase the proportion of functional high-affinity alpha6 subunit-containing receptors in granule cells of adult rat cerebellum.
    Neuropharmacology, 2003, Volume: 44, Issue:1

    Topics: Animals; Bicuculline; Binding, Competitive; Cells, Cultured; Cerebellum; Furosemide; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Patch-Clamp Techniques; Protein Subunits; Pyridazines; Rats; Rats, Wistar; Receptors, GABA-A; Zinc

2003
Rat alpha6beta2delta GABAA receptors exhibit two distinct and separable agonist affinities.
    The Journal of physiology, 2007, Jun-15, Volume: 581, Issue:Pt 3

    Topics: Action Potentials; Animals; beta-Alanine; Bicuculline; Crotonates; Desoxycorticosterone; Dose-Response Relationship, Drug; Female; Furosemide; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Imidazoles; Microinjections; Mutation; Neural Inhibition; Neurons; Oocytes; Picrotoxin; Pyridazines; Rats; Receptors, GABA-A; Sesterterpenes; Taurine; Xenopus laevis; Zinc

2007
Development of chloride-mediated inhibition in neurons of the anteroventral cochlear nucleus of gerbil (Meriones unguiculatus).
    Journal of neurophysiology, 2007, Volume: 98, Issue:3

    Topics: Animals; Brain Stem; Chlorides; Cochlear Nucleus; Electrophysiology; Furosemide; GABA Antagonists; gamma-Aminobutyric Acid; Gerbillinae; Glycine; Muscimol; Neurons; Pyridazines; Receptors, GABA-A; Synaptic Transmission

2007
Presynaptic actions of propofol enhance inhibitory synaptic transmission in isolated solitary tract nucleus neurons.
    Brain research, 2009, Aug-25, Volume: 1286

    Topics: Anesthetics, Intravenous; Animals; Bicuculline; Cells, Cultured; Furosemide; GABA Antagonists; Inhibitory Postsynaptic Potentials; Male; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Presynaptic Terminals; Propofol; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sodium Potassium Chloride Symporter Inhibitors; Solitary Nucleus; Synaptic Transmission

2009
Pre- and postsynaptic modulation of monosynaptic reflex by GABAA receptors on turtle spinal cord.
    The Journal of physiology, 2010, Jul-15, Volume: 588, Issue:Pt 14

    Topics: Animals; Bicuculline; Furosemide; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Motor Neurons; Picrotoxin; Presynaptic Terminals; Pyridazines; Receptors, GABA-A; Reflex, Monosynaptic; Spinal Cord; Synaptic Potentials; Turtles

2010