Page last updated: 2024-09-02

sr 95531 and chlorine

sr 95531 has been researched along with chlorine in 31 studies

Compound Research Comparison

Studies
(sr 95531)
Trials
(sr 95531)
Recent Studies (post-2010)
(sr 95531)
Studies
(chlorine)
Trials
(chlorine)
Recent Studies (post-2010) (chlorine)
610020945,6895717,225
610020911,761963,150

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19902 (6.45)18.7374
1990's18 (58.06)18.2507
2000's6 (19.35)29.6817
2010's5 (16.13)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Banerjee, PK; Depaulis, A; Hechler, V; Snead, OC; Vergnes, M1
Harris, RA; Leidenheimer, NJ1
Catt, KJ; Stojilković, SS; Virmani, MA1
Buck, KJ; Harris, RA1
Galpern, WR; Greenblatt, DJ; Lumpkin, M; Miller, LG; Shader, RI1
Browning, MD; Dunwiddie, TV; Hahner, LD; Harris, RA; Leidenheimer, NJ1
Ho, IK; Yu, S1
Mienville, JM; Vicini, S1
Ikeda, M; Knapp, RJ; Malatynska, E; Yamamura, HI1
Dieudonné, S1
Lukasiewicz, PD; Werblin, FS1
Mody, I; Soltesz, I1
Lukasiewicz, PD; Maple, BR; Werblin, FS1
Lanius, RA; Pasqualotto, BA; Shaw, CA1
Cestari, IN; Uchida, I; Yang, J1
Amato, F; Biggio, G; Deserra, T; Motzo, C; Murgia, A; Sanna, E1
Biggio, G; Casula, A; Murgia, A; Sanna, E1
Frye, CA; Vongher, JM1
Homanics, GE; Korpi, ER; Kralic, JE; Morrow, AL; O'Buckley, TK1
Covey, DF; Eisenman, LN; Jinadasa, D; Mennerick, S; Shu, HJ; Zorumski, CF1
Aradi, I; Maccaferri, G1
Heinrich, M; Milenković, I; Reinert, T; Rübsamen, R; Turecek, R; Witte, M1
Augustine, GJ; Berglund, K; Feng, G; Hall, WC; Kuner, T; Schleich, W; Wang, H1
Hirasawa, H; Puopolo, M; Raviola, E1
Achilles, K; Kilb, W; Kolbaev, SN; Luhmann, HJ1
Altmüller, J; Cichy, A; Gisselmann, G; Hatt, H; Lehmann, R; Lübbert, M; Radtke, D; Schöbel, N; Schreiner, BS; Spector, AC; Spehr, J; Wetzel, CH1
Gonzalez-Islas, C; Lindsly, C; Wenner, P1
Biscocho, D; Cook, JG; Leise, EM; Long, J; Shah, N1
Asami, S; Doi, M; Fukuda, H; Ito, Y; Koshiba, T; Murakoshi, Y1
Akahane, K; Fukuda, H; Ito, Y; Kimura, Y; Miyasaka, T1
Chesnoy-Marchais, D1

Other Studies

31 other study(ies) available for sr 95531 and chlorine

ArticleYear
The GABAA receptor complex in experimental absence seizures in rat: an autoradiographic study.
    Neuroscience letters, 1992, Jun-08, Volume: 140, Issue:1

    Topics: Animals; Autoradiography; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; Chlorides; Convulsants; Epilepsy, Absence; Flunitrazepam; GABA-A Receptor Antagonists; Ion Channels; Ionophores; Male; Membrane Proteins; Muscimol; Organ Specificity; Pyramidal Tracts; Pyridazines; Rats; Rats, Wistar; Receptors, GABA-A; Sulfur Radioisotopes; Tritium

1992
A transient osmotic permeabilization method for the introduction of impermeant molecules into functional brain membrane vesicles.
    Journal of neuroscience methods, 1991, Volume: 40, Issue:2-3

    Topics: Alkaline Phosphatase; Animals; Capsules; Carbon Radioisotopes; Cell Membrane; Cell Membrane Permeability; Chloride Channels; Chlorides; Chlorine; Concanavalin A; Flunitrazepam; Hypotonic Solutions; Membrane Proteins; Mice; Mice, Inbred ICR; Muscimol; Pyridazines; Radioisotope Dilution Technique; Radioisotopes; Receptors, Concanavalin A; Receptors, GABA-A; Sucrose; Tritium

1991
Stimulation of luteinizing hormone release by gamma-aminobutyric acid (GABA) agonists: mediation by GABAA-type receptors and activation of chloride and voltage-sensitive calcium channels.
    Endocrinology, 1990, Volume: 126, Issue:5

    Topics: Amino Acid Sequence; Animals; Baclofen; Calcium Channels; Cells, Cultured; Chloride Channels; Chlorides; Female; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Isoxazoles; Luteinizing Hormone; Membrane Proteins; Molecular Sequence Data; Muscimol; Nifedipine; Pituitary Gland, Anterior; Pyridazines; Rats; Rats, Inbred Strains; Receptors, GABA-A

1990
Benzodiazepine agonist and inverse agonist actions on GABAA receptor-operated chloride channels. II. Chronic effects of ethanol.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 253, Issue:2

    Topics: Animals; Azides; Benzodiazepines; Brain; Carbolines; Chloride Channels; Chlorides; Convulsants; Ethanol; Flunitrazepam; GABA Antagonists; Male; Membrane Proteins; Mice; Mice, Inbred ICR; Pyridazines; Receptors, GABA-A; Substance Withdrawal Syndrome; Tritium

1990
Chronic benzodiazepine administration. VI. A partial agonist produces behavioral effects without tolerance or receptor alterations.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 254, Issue:1

    Topics: Animals; Behavior, Animal; Benzodiazepines; Benzodiazepinones; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Dose-Response Relationship, Drug; Drug Tolerance; Male; Mice; Motor Activity; Pyridazines; Receptors, GABA-A

1990
Phosphorylation-independent effects of second messenger system modulators on gamma-aminobutyric acidA receptor complex function.
    Molecular pharmacology, 1990, Volume: 38, Issue:6

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Chlorides; Colforsin; Cyclic AMP; Edetic Acid; Isoquinolines; Mice; Mice, Inbred ICR; Muscimol; Phosphorylation; Piperazines; Protein Kinases; Pyridazines; Receptors, GABA-A; Second Messenger Systems

1990
Effects of GABA antagonists, SR 95531 and bicuculline, on GABAA receptor-regulated chloride flux in rat cortical synaptoneurosomes.
    Neurochemical research, 1990, Volume: 15, Issue:9

    Topics: Animals; Bicuculline; Cerebral Cortex; Chlorides; Chlorine; GABA Antagonists; In Vitro Techniques; Male; Pyridazines; Radioisotopes; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptosomes

1990
A pyridazinyl derivative of gamma-aminobutyric acid (GABA), SR 95531, is a potent antagonist of Cl- channel opening regulated by GABAA receptors.
    Neuropharmacology, 1987, Volume: 26, Issue:7A

    Topics: Animals; Bicuculline; Chlorides; Electrophysiology; Ion Channels; Pyridazines; Rats; Receptors, GABA-A; Synapses

1987
Amoxapine inhibition of GABA-stimulated chloride conductance: investigations of potential sites of activity.
    Life sciences, 1989, Volume: 45, Issue:20

    Topics: Amoxapine; Animals; Cerebral Cortex; Chlorides; Dibenzoxazepines; Dose-Response Relationship, Drug; Flumazenil; Flunitrazepam; GABA Antagonists; Ligands; Male; Pyridazines; Rats; Rats, Inbred Strains; Receptors, GABA-A

1989
Glycinergic synaptic currents in Golgi cells of the rat cerebellum.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Feb-28, Volume: 92, Issue:5

    Topics: Animals; Cerebellar Cortex; Chlorides; Evoked Potentials; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Ion Channel Gating; Male; Membrane Potentials; Neural Inhibition; Pyridazines; Rats; Rats, Wistar; Receptors, Glycine; Strychnine; Synapses; Synaptic Transmission

1995
A novel GABA receptor modulates synaptic transmission from bipolar to ganglion and amacrine cells in the tiger salamander retina.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1994, Volume: 14, Issue:3 Pt 1

    Topics: Animals; Calcium; Chlorides; Crotonates; Electrophysiology; GABA-A Receptor Antagonists; Light; Neurotransmitter Agents; Picrotoxin; Pyridazines; Receptors, GABA; Receptors, GABA-A; Retina; Retinal Ganglion Cells; Synaptic Transmission; Urodela

1994
Patch-clamp recordings reveal powerful GABAergic inhibition in dentate hilar neurons.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1994, Volume: 14, Issue:4

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Chlorides; Electrophysiology; GABA-A Receptor Antagonists; Hippocampus; In Vitro Techniques; Kinetics; Male; Membrane Potentials; Neurons; Picrotoxin; Pyridazines; Quinoxalines; Rats; Rats, Wistar; Receptors, GABA-A; Tetrodotoxin; Time Factors

1994
A novel GABA receptor on bipolar cell terminals in the tiger salamander retina.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1994, Volume: 14, Issue:3 Pt 1

    Topics: Animals; Bicuculline; Chlorides; Crotonates; Electrophysiology; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Muscimol; Pentobarbital; Picrotoxin; Pyridazines; Receptors, GABA; Receptors, GABA-A; Retina; Retinal Ganglion Cells; Urodela

1994
gamma-Aminobutyric acidA receptor regulation by a chloride-dependent kinase and a sodium-dependent phosphatase.
    Brain research. Molecular brain research, 1993, Volume: 20, Issue:3

    Topics: Animals; Calcium; Cerebral Cortex; Chloride Channels; Chlorides; GABA Antagonists; Models, Biological; Phosphoprotein Phosphatases; Phosphorylation; Potassium; Protein Binding; Protein Kinase Inhibitors; Protein Kinases; Protein Processing, Post-Translational; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, GABA; Sodium

1993
The differential antagonism by bicuculline and SR95531 of pentobarbitone-induced currents in cultured hippocampal neurons.
    European journal of pharmacology, 1996, Jun-20, Volume: 307, Issue:1

    Topics: Anesthetics, General; Anesthetics, Intravenous; Animals; Bicuculline; Binding Sites; Cells, Cultured; Chloride Channels; Chlorides; Etomidate; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Hippocampus; Models, Molecular; Neurons; Pentobarbital; Pyridazines; Rats; Receptors, GABA-A

1996
Expression of native GABAA receptors in Xenopus oocytes injected with rat brain synaptosomes.
    Journal of neurochemistry, 1996, Volume: 67, Issue:5

    Topics: Anesthetics; Animals; Brain; Cell Membrane; Chloride Channels; Chlorides; Diazepam; Female; GABA Antagonists; gamma-Aminobutyric Acid; Membrane Potentials; Oocytes; Picrotoxin; Pregnanediones; Pyridazines; Rats; Receptors, GABA-A; Synaptosomes; Xenopus laevis; Zinc Compounds

1996
Differential subunit dependence of the actions of the general anesthetics alphaxalone and etomidate at gamma-aminobutyric acid type A receptors expressed in Xenopus laevis oocytes.
    Molecular pharmacology, 1997, Volume: 51, Issue:3

    Topics: Anesthetics; Animals; Binding Sites; Chlorides; Etomidate; Oocytes; Picrotoxin; Pregnanediones; Pyridazines; Receptors, GABA-A; Recombinant Proteins; Xenopus laevis

1997
Progestins' rapid facilitation of lordosis when applied to the ventral tegmentum corresponds to efficacy at enhancing GABA(A)receptor activity.
    Journal of neuroendocrinology, 1999, Volume: 11, Issue:11

    Topics: Animals; Brain Mapping; Chlorides; Cricetinae; Drug Implants; Female; Functional Laterality; GABA Antagonists; gamma-Aminobutyric Acid; Ovariectomy; Posture; Progesterone; Progestins; Pyridazines; Rats; Rats, Long-Evans; Receptors, GABA-A; Sexual Behavior, Animal; Ventral Tegmental Area

1999
Molecular and pharmacological characterization of GABA(A) receptor alpha1 subunit knockout mice.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 302, Issue:3

    Topics: Animals; Autoradiography; Bicuculline; Blotting, Western; Cerebral Cortex; Chlorides; Convulsants; Female; GABA Agonists; GABA Antagonists; Kinetics; Ligands; Male; Mice; Mice, Knockout; Muscimol; Pyridazines; Radioligand Assay; Receptors, GABA-A; Seizures

2002
Slow actions of neuroactive steroids at GABAA receptors.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Jul-28, Volume: 24, Issue:30

    Topics: Animals; Binding Sites; Cell Membrane; Cells, Cultured; Chlorides; GABA Agonists; GABA Antagonists; gamma-Cyclodextrins; Hippocampus; Ion Channel Gating; Ion Transport; Kinetics; Ligands; Neurons; Oocytes; Patch-Clamp Techniques; Pregnanolone; Protein Binding; Pyridazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Recombinant Proteins; RNA, Messenger; Transfection; Xenopus

2004
Cell type-specific synaptic dynamics of synchronized bursting in the juvenile CA3 rat hippocampus.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Oct-27, Volume: 24, Issue:43

    Topics: Action Potentials; Animals; Chlorides; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Interneurons; Models, Neurological; Nerve Net; Neural Inhibition; Pyramidal Cells; Pyridazines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, GABA-A; Synapses; Synaptic Transmission; Time Factors

2004
Development of chloride-mediated inhibition in neurons of the anteroventral cochlear nucleus of gerbil (Meriones unguiculatus).
    Journal of neurophysiology, 2007, Volume: 98, Issue:3

    Topics: Animals; Brain Stem; Chlorides; Cochlear Nucleus; Electrophysiology; Furosemide; GABA Antagonists; gamma-Aminobutyric Acid; Gerbillinae; Glycine; Muscimol; Neurons; Pyridazines; Receptors, GABA-A; Synaptic Transmission

2007
Imaging synaptic inhibition throughout the brain via genetically targeted Clomeleon.
    Brain cell biology, 2008, Volume: 36, Issue:1-4

    Topics: Amygdala; Animals; Bicuculline; Brain; Cell Culture Techniques; Cerebellum; Chlorides; Diagnostic Imaging; Electric Stimulation; GABA Antagonists; Genetic Vectors; Hippocampus; Interneurons; Mice; Mice, Transgenic; Microscopy, Confocal; Neural Inhibition; Neurons; Pyridazines; Recombinant Fusion Proteins; Superior Colliculi; Synaptic Transmission; Transfection

2008
Extrasynaptic release of GABA by retinal dopaminergic neurons.
    Journal of neurophysiology, 2009, Volume: 102, Issue:1

    Topics: Animals; Cadmium; Calcium; Cells, Cultured; Cesium; Chlorides; Dopamine; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Exocytosis; GABA Antagonists; gamma-Aminobutyric Acid; Macrolides; Membrane Potentials; Mice; Mice, Inbred C57BL; Models, Biological; Neurons; Patch-Clamp Techniques; Pyridazines; Retina; Sodium Channel Blockers; Synapses; Synapsins; Tetrodotoxin; Tyrosine 3-Monooxygenase

2009
Effect of depolarizing GABA(A)-mediated membrane responses on excitability of Cajal-Retzius cells in the immature rat neocortex.
    Journal of neurophysiology, 2011, Volume: 106, Issue:4

    Topics: Action Potentials; Animals; Animals, Newborn; Chlorides; Differential Threshold; GABA Antagonists; GABAergic Neurons; gamma-Aminobutyric Acid; Interneurons; Ion Channel Gating; Membrane Potentials; Models, Neurological; Neocortex; Patch-Clamp Techniques; Pyridazines; Rats; Rats, Wistar; Receptors, GABA-A

2011
Trigeminal ganglion neurons of mice show intracellular chloride accumulation and chloride-dependent amplification of capsaicin-induced responses.
    PloS one, 2012, Volume: 7, Issue:11

    Topics: Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Signaling; Capsaicin; Cells, Cultured; Chloride Channels; Chlorides; Female; GABA-A Receptor Antagonists; Gene Expression; HEK293 Cells; Humans; Male; Membrane Potentials; Mice; Mice, Knockout; Neurons; Primary Cell Culture; Pyridazines; Receptors, GABA-A; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2; Synaptic Transmission; Transcriptome; Trigeminal Ganglion; TRPV Cation Channels

2012
Activity blockade and GABAA receptor blockade produce synaptic scaling through chloride accumulation in embryonic spinal motoneurons and interneurons.
    PloS one, 2014, Volume: 9, Issue:4

    Topics: Animals; Calibration; Chick Embryo; Chlorides; Fluorescence Resonance Energy Transfer; GABA-A Receptor Antagonists; Homeostasis; Interneurons; Motor Neurons; Neuronal Plasticity; Pyridazines; Receptors, GABA-A; Spinal Cord; Synapses; Synaptic Transmission; Time Factors; Xanthenes

2014
GABA is an inhibitory neurotransmitter in the neural circuit regulating metamorphosis in a marine snail.
    Developmental neurobiology, 2018, Volume: 78, Issue:7

    Topics: Aminooxyacetic Acid; Animals; Anions; Bicuculline; Chlorides; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Larva; Metamorphosis, Biological; Muscimol; Neurotransmitter Agents; Pyridazines; Receptors, GABA-A; Serotonin; Snails

2018
Characterization of antagonistic activity and binding properties of SR 95531, a pyridazinyl-GABA derivative, in rat brain and cultured cerebellar neuronal cells.
    Synapse (New York, N.Y.), 1992, Volume: 10, Issue:4

    Topics: Animals; Brain; Cells, Cultured; Cerebellum; Cerebral Cortex; Chlorine; GABA Antagonists; Kinetics; Male; Muscimol; Neurons; Pyridazines; Rats; Rats, Inbred Strains; Synaptosomes

1992
Inhibition of GABAA receptor chloride channel by quinolones and norfloxacin-biphenylacetic acid hybrid compounds.
    Neuropharmacology, 1996, Volume: 35, Issue:9-10

    Topics: Animals; Anti-Infective Agents; Chloride Channels; Chlorine; Enoxacin; GABA Agonists; GABA Antagonists; GABA-A Receptor Antagonists; Male; Muscimol; Norfloxacin; Phenylacetates; Pyridazines; Quinolones; Rats; Rats, Wistar; Synaptosomes

1996
Persistent GABAA/C responses to gabazine, taurine and beta-alanine in rat hypoglossal motoneurons.
    Neuroscience, 2016, 08-25, Volume: 330

    Topics: Animals; beta-Alanine; Bicuculline; Brain Stem; Central Nervous System Agents; Chlorine; GABA Agents; Hypoglossal Nerve; Midazolam; Motor Neurons; Neuroprotective Agents; Patch-Clamp Techniques; Pentobarbital; Phosphinic Acids; Pregnanolone; Pyridazines; Pyridines; Rats, Sprague-Dawley; Receptors, GABA; Receptors, GABA-A; Strychnine; Taurine; Tissue Culture Techniques

2016