Page last updated: 2024-08-26

sr 48968 and cp 99994

sr 48968 has been researched along with cp 99994 in 37 studies

Research

Studies (37)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	24 (64.86)	18.2507
2000's	13 (35.14)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Brawner, ME; Elshourbagy, NA; Foley, JJ; Giardina, GA; Griswold, DE; Hay, DW; Martin, LD; Medhurst, AD; Potts, W; Sarau, HM; Schmidt, DB; Webb, EF	1
Anthes, JC; Billah, M; Carruthers, N; Chapman, RW; Corboz, M; Crawley, Y; Cuss, FM; Eckel, S; Egan, RW; Fernandez, X; Greenfeder, S; Hey, JA; Kreutner, W; McLeod, R; Piwinski, J; Reichard, G; Richard, C; Rizzo, C; Sehring, S; Shih, NY; Ting, P	1
Besson, G; Drazen, JM; Israel, E; Lilly, CM; Rodger, IW	1
Drazen, JM; Haley, KJ; Hall, AE; Kobzik, L; Lilly, CM; Rodger, IW	1
Killingsworth, CR; Shore, SA	1
Alger, LE; Garland, A; Gitter, B; Nawrocki, AR; Necheles, J; Rodger, I; Solway, J; White, SR	1
Champion, E; Foulon, DM; Jones, TR; Masson, P; Rodger, IW	1
McKee, KT; Metters, KM; Millar, L; Rodger, IW	1
Brideau, C; Chan, CC; Ho, E; Rodger, IW; Savoie, C; Tousignant, C	1
Charette, L; Foulon, D; Jones, TR; Rodger, IW	1
Chan, CC; Rodger, IW; Savoie, C; Tousignant, C	1
Bartho, L; Holzer, P	1
Chrétien, L; Gobeil, F; Jukic, D; Nguyen, QT; Nguyen-Le, XK; Regoli, D	1
Bolser, DC; DeGennaro, FC; Hey, JA; McLeod, RL; O'Reilly, S	1
Chapman, RW; Mauser, PJ; Sherwood, JE	1
Henry, JL; Radhakrishnan, V	1
Jafri, MS; Weinreich, D	1
Buéno, L; Fioramonti, J; Garcia-Villar, R; McLean, PG	1
Chapman, RW; Egan, RW; Kreutner, W; Schilling, A; Selig, W; Sherwood, JE; Young, S	1
Colquhoun, EQ; Eldershaw, TP; Geraghty, DP; Griffiths, CD	1
Moore, KA; Taylor, GE; Weinreich, D	1
Di Maria, GU; Fabbri, LM; Geppetti, P; Rado, V; Ricciardolo, FL; Sterk, PJ	1
Chapman, RW; Kreutner, W; Nardo, C; Ng, K; Schilling, A; Young, S	1
Lee, LY; Wu, ZX	1
Gerard, NP; Nguyen, N; Pasricha, PJ; Saban, MR; Saban, R	1
Chen, G; Lee, LY; Wu, ZX; Zhou, D	1
Moore, KA; Undem, BJ; Weinreich, D	1
Kanda, M; Kurahashi, K; Nakamura, S; Shirahase, H	1
Hey, JA; Rizzo, CA	1
Filer-Maerten, S; Hay, DW; Hieble, JP; Ruggieri, MR	1
Oh, EJ; Thompson, LP; Weinreich, D	1
Bjorling, DE; Jerde, TJ; Nakada, SY; Saban, R	1
Kashon, ML; Krajnak, KM; Kwong, K; Lee, LY; Wise, PM; Wu, ZX	1
Corboz, MR; Hey, JA; Phillips, JE	1
Corboz, MR; Fernandez, X; Hey, JA; Monahan, ME; Rizzo, CA; Tozzi, S	1
Ardizzone, C; Bellantuono, V; Cassano, G; Lippe, C	1
Corboz, MR; Fernandez, X; Hey, JA	1

Other Studies

37 other study(ies) available for sr 48968 and cp 99994

Article	Year
Nonpeptide tachykinin receptor antagonists: I. Pharmacological and pharmacokinetic characterization of SB 223412, a novel, potent and selective neurokinin-3 receptor antagonist. The Journal of pharmacology and experimental therapeutics, 1997, Volume: 281, Issue:3 Topics: Animals; Calcium; CHO Cells; Cricetinae; Dogs; Humans; Mice; Piperidines; Quinolines; Rabbits; Radioligand Assay; Rats; Receptors, Neurokinin-3; Receptors, Tachykinin	1997
SCH 206272: a potent, orally active tachykinin NK(1), NK(2), and NK(3) receptor antagonist. European journal of pharmacology, 2002, Aug-23, Volume: 450, Issue:2 Topics: Acetamides; Administration, Oral; Animals; Bronchoconstriction; Capillary Permeability; Capsaicin; CHO Cells; Cough; Cricetinae; Dogs; Dose-Response Relationship, Drug; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurokinin-1 Receptor Antagonists; Piperidines; Pulmonary Artery; Radioligand Assay; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Vas Deferens	2002
Capsaicin-induced airway obstruction in tracheally perfused guinea pig lungs. American journal of respiratory and critical care medicine, 1994, Volume: 149, Issue:5 Topics: Animals; Benzamides; Bronchoconstriction; Capsaicin; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Male; Methacholine Chloride; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Perfusion; Piperidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P; Trachea	1994
Substance P-induced histamine release in tracheally perfused guinea pig lungs. Journal of applied physiology (Bethesda, Md. : 1985), 1995, Volume: 78, Issue:4 Topics: Animals; Benzamides; Bronchoconstriction; Capsaicin; Guinea Pigs; Histamine; In Vitro Techniques; Lung; Male; Mast Cells; Perfusion; Piperidines; Pyrilamine; Receptors, Histamine; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P	1995
Tachykinin receptors mediating contraction of guinea pig lung strips. Regulatory peptides, 1995, May-30, Volume: 57, Issue:2 Topics: Acetylcholine; Animals; Benzamides; Biphenyl Compounds; Dipeptides; Guinea Pigs; In Vitro Techniques; Lung; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin B; Peptide Fragments; Piperidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Tachykinin; Substance P; Trachea	1995
Proliferation of guinea pig tracheal epithelial cells in coculture with rat dorsal root ganglion neural cells. The American journal of physiology, 1995, Volume: 268, Issue:6 Pt 1 Topics: Animals; Animals, Newborn; Benzamides; Bromodeoxyuridine; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Cell Communication; Cell Cycle; Cell Division; Cells, Cultured; Epithelial Cells; Epithelium; Ganglia, Spinal; Guinea Pigs; Neurokinin A; Neurokinin-1 Receptor Antagonists; Neurons; Peptide Fragments; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Tachykinin; S Phase; Trachea	1995
NK1 and NK2 receptors mediate tachykinin and resiniferatoxin-induced bronchospasm in guinea pigs. The American review of respiratory disease, 1993, Volume: 148, Issue:4 Pt 1 Topics: Animals; Benzamides; Bronchial Spasm; Bronchoconstriction; Diterpenes; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; Male; Neurokinin A; Peptide Fragments; Piperidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P; Tachykinins	1993
Identification of both NK1 and NK2 receptors in guinea-pig airways. British journal of pharmacology, 1993, Volume: 110, Issue:2 Topics: Animals; Benzamides; Chromatography, High Pressure Liquid; Guinea Pigs; In Vitro Techniques; Iodine Radioisotopes; Lung; Male; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Piperidines; Radioligand Assay; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Respiratory System; Substance P; Trachea	1993
Evaluation of bronchoconstriction induced by neurokinins and its inhibition by selective nonpeptide antagonists in conscious guinea pigs, using a double-chamber plethysmograph technique. Canadian journal of physiology and pharmacology, 1994, Volume: 72, Issue:1 Topics: Airway Resistance; Animals; Benzamides; Bronchoconstriction; Bronchodilator Agents; Guinea Pigs; Histamine; Indomethacin; Leukotriene D4; Male; Neurokinin A; Parasympatholytics; Piperidines; Plethysmography; Propionates; Pyrilamine; Quinolines	1994
Neurokinin (NK2) receptors mediate nonadrenergic noncholinergic contractile responses to electrical stimulation and resiniferatoxin in guinea pig trachea. Canadian journal of physiology and pharmacology, 1994, Volume: 72, Issue:2 Topics: Airway Resistance; Animals; Arginine; Benzamides; Diterpenes; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Neurotoxins; NG-Nitroarginine Methyl Ester; Piperidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Tetrodotoxin; Trachea	1994
Involvement of NK1 and NK2 receptors in pulmonary responses elicited by non-adrenergic, non-cholinergic vagal stimulation in guinea-pigs. The Journal of pharmacy and pharmacology, 1995, Volume: 47, Issue:11 Topics: Animals; Benzamides; Bronchi; Bronchoconstriction; Capillary Permeability; Enalapril; Guinea Pigs; Male; Piperidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P; Thiorphan; Trachea; Vagus Nerve	1995
The inhibitory modulation of guinea-pig intestinal peristalsis caused by capsaicin involves calcitonin gene-related peptide and nitric oxide. Naunyn-Schmiedeberg's archives of pharmacology, 1995, Volume: 353, Issue:1 Topics: Animals; Benzamides; Calcitonin Gene-Related Peptide; Capsaicin; Dose-Response Relationship, Drug; Female; Guinea Pigs; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peristalsis; Piperidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Reflex	1995
Neurokinin receptors in the guinea pig ileum. Pharmacology, 1996, Volume: 52, Issue:1 Topics: Acetylcholine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzamides; Biphenyl Compounds; Guinea Pigs; Ileum; Male; Myenteric Plexus; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Piperidines; Pyrrolidonecarboxylic Acid; Radioligand Assay; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Stereoisomerism; Structure-Activity Relationship; Substance P	1996
Central antitussive activity of the NK1 and NK2 tachykinin receptor antagonists, CP-99,994 and SR 48968, in the guinea-pig and cat. British journal of pharmacology, 1997, Volume: 121, Issue:2 Topics: Animals; Antitussive Agents; Benzamides; Cats; Central Nervous System; Cough; Dose-Response Relationship, Drug; Guinea Pigs; Piperidines	1997
Bronchoconstrictor and respiratory effects of neurokinin A in dogs. The Journal of pharmacology and experimental therapeutics, 1997, Volume: 283, Issue:2 Topics: Animals; Benzamides; Bronchoconstriction; Dogs; Ipratropium; Male; Neurokinin A; Piperidines; Receptors, Neurokinin-2; Respiration	1997
Electrophysiological evidence that neurokinin A acts via NK-1 receptors in the cat dorsal horn. The European journal of neuroscience, 1997, Volume: 9, Issue:9 Topics: Animals; Benzamides; Biphenyl Compounds; Cats; Iontophoresis; Neurokinin A; Piperidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Spinal Cord; Stereoisomerism; Substance P; Synapses	1997
Substance P regulates Ih via a NK-1 receptor in vagal sensory neurons of the ferret. Journal of neurophysiology, 1998, Volume: 79, Issue:2 Topics: Action Potentials; Animals; Benzamides; Cations; Ferrets; Ion Channel Gating; Ion Transport; Male; Membrane Potentials; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Nodose Ganglion; Patch-Clamp Techniques; Piperidines; Receptors, Neurokinin-1; Substance P; Vagus Nerve	1998
Effects of tachykinin receptor antagonists on the rat jejunal distension pain response. European journal of pharmacology, 1998, Mar-26, Volume: 345, Issue:3 Topics: Analgesics, Non-Narcotic; Animals; Benzamides; Blood Pressure; Jejunum; Male; Neurokinin-1 Receptor Antagonists; Pain; Piperidines; Pressure; Rats; Rats, Wistar; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Tachykinin; Regression Analysis	1998
A method to measure dual NK1/NK2-antagonist activity in dogs. Journal of pharmacological and toxicological methods, 1998, Volume: 39, Issue:2 Topics: Animals; Benzamides; Dogs; Male; Neurokinin A; Piperidines; Propofol; Receptors, Neurokinin-2; Receptors, Tachykinin; Respiratory System; Substance P; Tachykinins	1998
Acute and chronic effects of capsaicin in perfused rat muscle: the role of tachykinins and calcitonin gene-related peptide. The Journal of pharmacology and experimental therapeutics, 1998, Volume: 287, Issue:2 Topics: Animals; Benzamides; Calcitonin Gene-Related Peptide; Capsaicin; Male; Muscle, Skeletal; Neurokinin A; Peptide Fragments; Piperidines; Rats; Rats, Wistar; Receptors, Neurokinin-2; Substance P	1998
Serotonin unmasks functional NK-2 receptors in vagal sensory neurones of the guinea-pig. The Journal of physiology, 1999, Jan-01, Volume: 514 ( Pt 1) Topics: Animals; Benzamides; Cycloheximide; Enzyme Inhibitors; Guinea Pigs; Hydrazines; Imidazoles; Indoles; Male; Membrane Potentials; Neurons, Afferent; Nitric Oxide; Nitric Oxide Donors; Nodose Ganglion; omega-N-Methylarginine; Penicillamine; Piperidines; Protein Synthesis Inhibitors; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Antagonists; Substance P; Tropisetron	1999
Bronchoconstriction induced by citric acid inhalation in guinea pigs: role of tachykinins, bradykinin, and nitric oxide. American journal of respiratory and critical care medicine, 1999, Volume: 159, Issue:2 Topics: Administration, Inhalation; Adrenergic beta-Antagonists; Airway Resistance; Animals; Asthma; Benzamides; Bradykinin; Bradykinin Receptor Antagonists; Bronchoconstriction; Citric Acid; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enzyme Inhibitors; Guinea Pigs; Male; Nitric Oxide Synthase; omega-N-Methylarginine; Piperidines; Receptors, Neurokinin-2	1999
Combined NK(1)and NK(2)receptor antagonists on the bronchoconstrictor response to NKA in dogs. Pulmonary pharmacology & therapeutics, 1999, Volume: 12, Issue:4 Topics: Animals; Benzamides; Bronchial Spasm; Bronchoconstriction; Disease Models, Animal; Dogs; Male; Neurokinin-1 Receptor Antagonists; Piperidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Tachykinins	1999
Airway hyperresponsiveness induced by chronic exposure to cigarette smoke in guinea pigs: role of tachykinins. Journal of applied physiology (Bethesda, Md. : 1985), 1999, Volume: 87, Issue:5 Topics: Acetylcholine; Air Pressure; Animals; Benzamides; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Capsaicin; Cell Count; Dose-Response Relationship, Drug; Guinea Pigs; Male; Neurokinin A; Neuropeptides; Nicotiana; Piperidines; Plants, Toxic; Receptors, Neurokinin-2; Smoke; Tachykinins; Vagotomy	1999
Nerve-mediated motility of ileal segments isolated from NK(1) receptor knockout mice. The American journal of physiology, 1999, Volume: 277, Issue:6 Topics: Animals; Benzamides; Dose-Response Relationship, Drug; Gastrointestinal Motility; Ileum; Male; Mice; Mice, Knockout; Neurokinin A; Neurons, Afferent; Nitric Oxide; Organ Culture Techniques; Piperidines; Receptors, Cholinergic; Receptors, Neurokinin-1; Substance P; Synaptic Transmission	1999
Airway hyperresponsiveness to cigarette smoke in ovalbumin-sensitized guinea pigs. American journal of respiratory and critical care medicine, 2000, Volume: 161, Issue:1 Topics: Acetylcholine; Airway Resistance; Animals; Benzamides; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Calcitonin Gene-Related Peptide; Disease Models, Animal; Eosinophils; Guinea Pigs; Leukocyte Count; Lung; Lung Compliance; Male; Neutrophils; Nicotiana; Ovalbumin; Piperidines; Plants, Toxic; Receptors, Neurokinin-2; Smoke	2000
Antigen inhalation unmasks NK-2 tachykinin receptor-mediated responses in vagal afferents. American journal of respiratory and critical care medicine, 2000, Volume: 161, Issue:1 Topics: Animals; Antigens; Benzamides; Disease Models, Animal; Guinea Pigs; Male; Membrane Potentials; Microscopy, Electron, Scanning; Neurokinin-1 Receptor Antagonists; Ovalbumin; Patch-Clamp Techniques; Piperidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P; Trachea; Tracheitis; Vagotomy; Vagus Nerve	2000
Endothelium-dependent relaxation followed by contraction mediated by NK(1) receptors in precontracted rabbit intrapulmonary arteries. British journal of pharmacology, 2000, Volume: 129, Issue:5 Topics: Animals; Benzamides; Benzoquinones; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; Lipoxygenase Inhibitors; Male; Muscle Contraction; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Piperidines; Pulmonary Artery; Rabbits; Receptors, Neurokinin-1; Substance P	2000
Activity of nonpeptide tachykinin antagonists on neurokinin a induced contractions in dog urinary bladder. The Journal of urology, 2000, Volume: 163, Issue:6 Topics: Animals; Benzamides; Dogs; Dose-Response Relationship, Drug; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Piperidines; Quinolines; Receptors, Neurokinin-2; Stereoisomerism; Urinary Bladder	2000
Role of neurokinin receptors in the behavioral effect of intravesical antigen infusion in guinea pig bladder. The Journal of urology, 2000, Volume: 164, Issue:1 Topics: Administration, Intravesical; Animals; Antigens; Behavior, Animal; Benzamides; Capsaicin; Dose-Response Relationship, Drug; Female; Guinea Pigs; Neurokinin-1 Receptor Antagonists; Ovalbumin; Pelvic Pain; Piperidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Urinary Bladder	2000
Sexually dimorphic regulation of NK-1 receptor-mediated electrophysiological responses in vagal primary afferent neurons. Journal of neurophysiology, 2000, Volume: 84, Issue:1 Topics: Animals; Benzamides; Electrophysiology; Estradiol; Female; Gonadal Steroid Hormones; Guinea Pigs; Male; Membrane Potentials; Neurons, Afferent; Nodose Ganglion; Orchiectomy; Ovariectomy; Piperidines; Pregnancy; Quinolines; Receptors, Neurokinin-1; Serotonin; Sex Characteristics; Substance P; Testosterone	2000
In vitro contractile effects of neurokinin receptor blockade in the human ureter. The Journal of urology, 2001, Volume: 166, Issue:4 Topics: Angiotensin-Converting Enzyme Inhibitors; Benzamides; Captopril; Dose-Response Relationship, Drug; Glycopeptides; Humans; Metalloendopeptidases; Muscle Contraction; Piperidines; Receptors, Neurokinin-2; Tachykinins; Ureter	2001
Chronic smoking enhances tachykinin synthesis and airway responsiveness in guinea pigs. American journal of respiratory cell and molecular biology, 2001, Volume: 25, Issue:3 Topics: Analysis of Variance; Animals; Benzamides; Bronchi; Bronchial Hyperreactivity; Calcitonin Gene-Related Peptide; Capsaicin; Guinea Pigs; In Situ Hybridization; Male; Neurons, Afferent; Piperidines; Protein Precursors; Radioimmunoassay; Random Allocation; Receptors, Neurokinin-2; Smoking; Tachykinins	2001
Tachykinin NK3 and NK1 receptor activation elicits secretion from porcine airway submucosal glands. British journal of pharmacology, 2003, Volume: 138, Issue:1 Topics: Animals; Benzamides; Dose-Response Relationship, Drug; Exocrine Glands; Neurokinin-1 Receptor Antagonists; Piperidines; Receptors, Neurokinin-1; Receptors, Neurokinin-3; Respiratory Mucosa; Swine; Trachea	2003
Increased blocking activity of combined tachykinin NK1- and NK2-receptor antagonists on tachykinergic bronchomotor responses in the guinea-pig. Autonomic & autacoid pharmacology, 2003, Volume: 23, Issue:1 Topics: Animals; Benzamides; Bronchi; Bronchoconstriction; Dose-Response Relationship, Drug; Drug Combinations; Guinea Pigs; In Vitro Techniques; Lung; Male; Muscle Contraction; Neurokinin-1 Receptor Antagonists; Piperidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2	2003
Eledoisin and Kassinin, but not Enterokassinin, stimulate ion transport in frog skin. Peptides, 2004, Volume: 25, Issue:11 Topics: Amino Acid Sequence; Animals; Benzamides; Eledoisin; Ion Transport; Kassinin; Piperidines; Quinolines; Rana esculenta; Skin; Skin Physiological Phenomena; Stereoisomerism; Tachykinins	2004
Increased blocking activity of combined tachykinin NK1- and NK2-receptor antagonists on hyperventilation-induced bronchoconstriction in the guinea pig. Pulmonary pharmacology & therapeutics, 2008, Volume: 21, Issue:1 Topics: Administration, Oral; Animals; Benzamides; Bronchoconstriction; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; Hyperventilation; Injections, Intravenous; Male; Neurokinin-1 Receptor Antagonists; Piperidines; Quinolines; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Respiratory Function Tests	2008