Page last updated: 2024-08-26

sr 48968 and 7,7-diphenyl-2-(1-imino-2-(2-methoxyphenyl)ethyl)perhydroisoindol-4-one

sr 48968 has been researched along with 7,7-diphenyl-2-(1-imino-2-(2-methoxyphenyl)ethyl)perhydroisoindol-4-one in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's20 (60.61)18.2507
2000's12 (36.36)29.6817
2010's1 (3.03)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Beaujouan, JC; Glowinski, J; Saffroy, M; Torrens, Y1
Andersson, KE; Igawa, Y; Ishizuka, O; Mattiasson, A1
Buéno, L; Julia, V; Morteau, O1
Fujii, T; Hirayama, Y; Kawamura, A; Yasumitsu, R1
Couture, R; Picard, P; Regoli, D1
Brain, SD; Newbold, P1
Andersson, KE; Ishizuka, O; Mattiasson, A2
Andersson, KE; Igawa, Y; Ishizuka, O; Lecci, A; Maggi, CA; Mattiasson, A1
Giuliani, S; Lecci, A; Maggi, CA; Santicioli, P1
Håkanson, R; Strichartz, GR; Tung, SR; Wang, ZY1
Auberson, S; Lundberg, JM1
Everaert, E; Germonpré, PR; Joos, GF; Kips, JC; Pauwels, RA1
Conte, B; Cutrufo, C; Manzini, S1
Ikeda, K; Kubota, H; Miyata, K; Orita, A; Tomioka, K; Yamada, T1
Cavero, I; Floch, A; Thiry, C1
Culman, J; Klee, S; Ohlendorf, C; Unger, T1
Hargreaves, RJ; Hill, RG; Shepheard, SL; Williamson, DJ1
Coudoré-Civiale, MA; Courteix, C; Eschalier, A; Fialip, J1
Geraghty, DP; Mazzone, SB2
Andersson, KE; Igawa, Y; Ishizuka, O; Nishizawa, O1
Baulmann, J; Culman, J; Herdegen, T; Spitznagel, H; Unger, T1
Yonehara, N; Yoshimura, M3
Coupar, IM; Kerr, KP; Mitchelson, F1
Andersson, KE; Gu, BJ; Igawa, Y; Ishizuka, O; Nishizawa, O1
Boucher, M; Coudoré-Civiale, M; Courteix, C; Eschalier, A; Fialip, J1
Couture, R; Lessard, A1
Gerard, NP; Kraneveld, AD; Morteau, O; Nijkamp, FP; Redegeld, FA; van der Kleij, HP1
Gaudreau, GA; Plourde, V1
Culman, J; Hunt, SP; Tauer, U; Zhao, Y1

Other Studies

33 other study(ies) available for sr 48968 and 7,7-diphenyl-2-(1-imino-2-(2-methoxyphenyl)ethyl)perhydroisoindol-4-one

ArticleYear
Involvement of septide-sensitive tachykinin receptors in inositol phospholipid hydrolysis in the rat urinary bladder.
    Peptides, 1995, Volume: 16, Issue:4

    Topics: Amino Acid Sequence; Animals; Benzamides; Hydrolysis; Indoles; Isoindoles; Male; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth; Neurokinin A; Peptide Fragments; Phosphatidylinositols; Piperidines; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Receptors, Tachykinin; Substance P; Urinary Bladder

1995
Capsaicin-induced bladder hyperactivity in normal conscious rats.
    The Journal of urology, 1994, Volume: 152, Issue:2 Pt 1

    Topics: Administration, Intravesical; Animals; Benzamides; Capsaicin; Consciousness; Dose-Response Relationship, Drug; Female; Hexamethonium; Hexamethonium Compounds; Indoles; Isoindoles; Morphine; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Tachykinin; Substance P; Urinary Bladder

1994
Involvement of neurokinin 1 and 2 receptors in viscerosensitive response to rectal distension in rats.
    Gastroenterology, 1994, Volume: 107, Issue:1

    Topics: Abdomen; Animals; Benzamides; Biphenyl Compounds; Colon; Colonic Diseases, Functional; Gastrointestinal Motility; Hypnotics and Sedatives; Indoles; Isoindoles; Male; Neurokinin A; Peptide Fragments; Piperidines; Rats; Rats, Wistar; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Tachykinin; Rectum; Substance P; Tachykinins

1994
NK1 receptors mediate tachykinin-induced plasma extravasation in the rat knee joint.
    Agents and actions, 1993, Volume: 40, Issue:3-4

    Topics: Animals; Benzamides; Capillary Permeability; Evans Blue; Hindlimb; Indoles; Isoindoles; Joints; Male; Neurokinin A; Neurokinin-1 Receptor Antagonists; Piperidines; Rats; Rats, Wistar; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P; Synovial Fluid; Tachykinins

1993
Cardiovascular and behavioural effects of centrally administered tachykinins in the rat: characterization of receptors with selective antagonists.
    British journal of pharmacology, 1994, Volume: 112, Issue:1

    Topics: Animals; Behavior, Animal; Benzamides; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Hemodynamics; Indoles; Injections, Intraventricular; Isoindoles; Male; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Oligopeptides; Piperidines; Rats; Rats, Wistar; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Tachykinin; Substance P; Tachykinins

1994
An investigation into the mechanism of capsaicin-induced oedema in rabbit skin.
    British journal of pharmacology, 1995, Volume: 114, Issue:3

    Topics: Alprostadil; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzamides; Bradykinin; Calcitonin Gene-Related Peptide; Capillary Permeability; Capsaicin; Catalase; Dexamethasone; Drug Interactions; Edema; Histamine; Indoles; Indomethacin; Injections, Intradermal; Injections, Intravenous; Isoindoles; Male; Piperidines; Rabbits; Regional Blood Flow; Ruthenium Red; Skin; Substance P; Vasodilator Agents

1995
Tachykinin effects on bladder activity in conscious normal rats.
    The Journal of urology, 1995, Volume: 154, Issue:1

    Topics: Administration, Intravesical; Animals; Benzamides; Female; Indoles; Injections, Intra-Arterial; Isoindoles; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Peptides, Cyclic; Piperidines; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-2; Substance P; Urinary Bladder; Urination

1995
Prostaglandin E2-induced bladder hyperactivity in normal, conscious rats: involvement of tachykinins?
    The Journal of urology, 1995, Volume: 153, Issue:6

    Topics: Administration, Intravesical; Animals; Benzamides; Consciousness; Dinoprostone; Female; Indoles; Injections, Intra-Arterial; Isoindoles; Muscle, Smooth; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Tachykinin; Tachykinins; Urinary Bladder

1995
Role of intrathecal tachykinins for micturition in unanaesthetized rats with and without bladder outlet obstruction.
    British journal of pharmacology, 1994, Volume: 113, Issue:1

    Topics: Analgesics; Animals; Benzamides; Cystoscopy; Female; Hypertrophy; Indoles; Injections, Intra-Arterial; Injections, Spinal; Isoindoles; Neurokinin-1 Receptor Antagonists; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-2; Tachykinins; Urinary Bladder; Urinary Bladder Neck Obstruction; Urinary Catheterization; Urination

1994
Involvement of spinal tachykinin NK1 and NK2 receptors in detrusor hyperreflexia during chemical cystitis in anaesthetized rats.
    European journal of pharmacology, 1994, Jul-01, Volume: 259, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; Animals; Benzamides; Cyclophosphamide; Cystitis; Indoles; Injections, Intravenous; Injections, Spinal; Isoindoles; Male; Neurokinin-1 Receptor Antagonists; Physalaemin; Piperidines; Rats; Rats, Wistar; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Spinal Cord; Urinary Incontinence; Urination

1994
Non-specific actions of the non-peptide tachykinin receptor antagonists, CP-96,345, RP 67580 and SR 48968, on neurotransmission.
    British journal of pharmacology, 1994, Volume: 111, Issue:1

    Topics: Action Potentials; Anesthetics, Local; Animals; Benzamides; Biphenyl Compounds; Bupivacaine; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Indoles; Iris; Isoindoles; Male; Muscle Contraction; Muscle, Smooth; Piperidines; Procaine; Rabbits; Rana catesbeiana; Receptors, Tachykinin; Sciatic Nerve; Synaptic Transmission; Vas Deferens

1994
Lactic acid-induced plasma protein extravasation in rat airways by stimulation of sensory nerves and NK1 receptor activation.
    Pharmacology & toxicology, 1993, Volume: 73, Issue:6

    Topics: Animals; Benzamides; Blood Proteins; Bronchi; Capsaicin; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Indoles; Isoindoles; Lactates; Lactic Acid; Male; Nasal Mucosa; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Respiratory Physiological Phenomena; Respiratory System; Trachea

1993
Characterization of neurogenic inflammation in the airways of two highly inbred rat strains.
    American journal of respiratory and critical care medicine, 1995, Volume: 152, Issue:6 Pt 1

    Topics: Animals; Benzamides; Blood Pressure; Bronchi; Capillary Permeability; Capsaicin; Cimetidine; Coloring Agents; Dose-Response Relationship, Drug; Evans Blue; Histamine Antagonists; Indoles; Inflammation; Isoindoles; Methysergide; Neurokinin-1 Receptor Antagonists; Piperidines; Pyrilamine; Rats; Rats, Inbred F344; Rats, Inbred Strains; Receptors, Neurokinin-1; Serotonin; Serotonin Antagonists; Substance P; Trachea

1995
Electrocorticographic desynchronization after application of visceral and somatic noxious stimuli in urethane-anesthetized rats: effect of intrathecal administration of tachykinin (NK 1 or NK 2) receptor antagonists.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 276, Issue:1

    Topics: Acetylcholine; Administration, Topical; Anesthesia; Animals; Benzamides; Capsaicin; Cortical Synchronization; Electric Stimulation; Indoles; Injections, Spinal; Isoindoles; Lidocaine; Male; Perineum; Physalaemin; Piperidines; Rats; Rats, Wistar; Receptors, Tachykinin; Sensitivity and Specificity; Urethane; Urinary Bladder

1996
RP67580, a neurokinin1 receptor antagonist, decreased restraint stress-induced defecation in rat.
    Neuroscience letters, 1995, Sep-29, Volume: 198, Issue:2

    Topics: Analgesics; Animals; Benzamides; Capsaicin; Defecation; Dose-Response Relationship, Drug; Indoles; Isoindoles; Male; Neurokinin-1 Receptor Antagonists; Piperidines; Rats; Rats, Wistar; Receptors, Neurokinin-2; Restraint, Physical; Stereoisomerism; Stress, Psychological; Substance P

1995
Pharmacological evidence that NK-2 tachykinin receptors mediate hypotension in the guinea pig but not in the rat.
    Fundamental & clinical pharmacology, 1996, Volume: 10, Issue:4

    Topics: Animals; Benzamides; Blood Pressure; Guinea Pigs; Hypotension; Indoles; Isoindoles; Male; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Piperidines; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P

1996
Effect of tachykinin receptor inhibition in the brain on cardiovascular and behavioral responses to stress.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 280, Issue:1

    Topics: Animals; Behavior, Animal; Benzamides; Biphenyl Compounds; Blood Pressure; Brain; Heart Rate; Indoles; Isoindoles; Male; Neurokinin-1 Receptor Antagonists; Periaqueductal Gray; Piperidines; Rats; Rats, Wistar; Receptors, Neurokinin-2; Stress, Physiological

1997
Intravital microscope studies on the effects of neurokinin agonists and calcitonin gene-related peptide on dural vessel diameter in the anaesthetized rat.
    Cephalalgia : an international journal of headache, 1997, Volume: 17, Issue:4

    Topics: Anesthetics; Animals; Benzamides; Blood Pressure; Calcitonin Gene-Related Peptide; Dura Mater; Indoles; Isoindoles; Male; Microscopy, Video; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-2; Receptors, Tachykinin; Substance P; Vasodilator Agents

1997
Effect of tachykinin receptor antagonists in experimental neuropathic pain.
    European journal of pharmacology, 1998, Nov-20, Volume: 361, Issue:2-3

    Topics: Analgesics; Animals; Benzamides; Biphenyl Compounds; Denervation; Diabetes Mellitus, Experimental; Indoles; Isoindoles; Male; Neurokinin-1 Receptor Antagonists; Pain; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Tachykinin; Sciatic Nerve

1998
Respiratory action of capsaicin microinjected into the nucleus of the solitary tract: involvement of vanilloid and tachykinin receptors.
    British journal of pharmacology, 1999, Volume: 127, Issue:2

    Topics: Anesthesia; Animals; Benzamides; Capsaicin; Dose-Response Relationship, Drug; Indoles; Isoindoles; Male; Microinjections; Neurokinin-1 Receptor Antagonists; Piperidines; Rats; Rats, Wistar; Receptors, Drug; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Tachykinin; Respiratory Mechanics; Solitary Nucleus; Tidal Volume

1999
Role of supraspinal tachykinins for volume- and L-dopa-induced bladder activity in normal conscious rats.
    Neurourology and urodynamics, 2000, Volume: 19, Issue:1

    Topics: Animals; Benzamides; Brain; Female; Indoles; Injections, Intraventricular; Isoindoles; Levodopa; Methylene Blue; Neurokinin-1 Receptor Antagonists; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-2; Reference Values; Tachykinins; Tissue Distribution; Urinary Bladder; Urine

2000
Tachykinin receptor inhibition and c-Fos expression in the rat brain following formalin-induced pain.
    Neuroscience, 2000, Volume: 95, Issue:3

    Topics: Analgesics; Animals; Behavior, Animal; Benzamides; Brain; Formaldehyde; Grooming; Indoles; Injections, Intraventricular; Isoindoles; Male; Pain; Piperidines; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, Tachykinin

2000
Interaction between nitric oxide and substance P on heat-induced inflammation in rat paw.
    Neuroscience research, 2000, Volume: 36, Issue:1

    Topics: Analgesics; Animals; Benzamides; Evans Blue; Forelimb; Hyperthermia, Induced; Indoles; Inflammation; Isoindoles; Male; Neurons, Afferent; NG-Nitroarginine Methyl Ester; Nitric Oxide; Piperidines; Rats; Rats, Sprague-Dawley; Skin; Substance P

2000
Tachykinins play a minor role in mediating the third phase of the contractile response to vagal nerve stimulation of the guinea-pig oesophagus.
    Neuropeptides, 2000, Volume: 34, Issue:1

    Topics: Animals; Benzamides; Electric Stimulation; Esophagus; Guinea Pigs; In Vitro Techniques; Indoles; Isoindoles; Male; Muscle Contraction; Neurokinin-1 Receptor Antagonists; Piperidines; Quinuclidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Tachykinin; Vagus Nerve

2000
Respiratory actions of tachykinins in the nucleus of the solitary tract: characterization of receptors using selective agonists and antagonists.
    British journal of pharmacology, 2000, Volume: 129, Issue:6

    Topics: Animals; Benzamides; Indoles; Isoindoles; Male; Microinjections; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Piperidines; Rats; Rats, Wistar; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Tachykinin; Respiratory Mechanics; Solitary Nucleus; Substance P; Tachykinins; Tidal Volume

2000
Role of supraspinal tachykinins for micturition in conscious rats with and without bladder outlet obstruction.
    Naunyn-Schmiedeberg's archives of pharmacology, 2000, Volume: 361, Issue:5

    Topics: Analgesics; Animals; Benzamides; Catheterization; Female; Indoles; Isoindoles; Methylene Blue; Neurokinin-1 Receptor Antagonists; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-2; Tachykinins; Tissue Distribution; Urinary Bladder; Urinary Bladder Neck Obstruction; Urinary Incontinence; Urination

2000
Evidence for an involvement of tachykinins in allodynia in streptozocin-induced diabetic rats.
    European journal of pharmacology, 2000, Jul-28, Volume: 401, Issue:1

    Topics: Analgesics; Animals; Benzamides; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Indoles; Isoindoles; Male; Neurokinin-1 Receptor Antagonists; Pain; Pain Threshold; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-2; Tachykinins; Temperature; Time Factors

2000
Influence of capsaicin cream in rats with peripheral neuropathy.
    Pharmacological research, 2001, Volume: 44, Issue:2

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics; Animals; Benzamides; Capsaicin; Carrageenan; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hyperalgesia; Indoles; Isoindoles; Male; Neuroprotective Agents; Pain; Peripheral Nervous System Diseases; Piperidines; Postoperative Period; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Substance Withdrawal Syndrome; Time Factors

2001
Modulation of cardiac activity by tachykinins in the rat substantia nigra.
    British journal of pharmacology, 2001, Volume: 134, Issue:8

    Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Atropine; Benzamides; Blood Pressure; Hemodynamics; Indoles; Isoindoles; Male; Microinjections; Muscarinic Antagonists; Neurokinin-1 Receptor Antagonists; Oligopeptides; Peptide Fragments; Piperidines; Rats; Rats, Wistar; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Tachykinin; Substance P; Substantia Nigra; Tachycardia; Tachykinins

2001
The tachykinin NK1 receptor is crucial for the development of non-atopic airway inflammation and hyperresponsiveness.
    European journal of pharmacology, 2003, Aug-29, Volume: 476, Issue:3

    Topics: Administration, Intranasal; Airway Obstruction; Animals; Benzamides; Dinitrofluorobenzene; Hypersensitivity; In Vitro Techniques; Indoles; Inflammation; Isoindoles; Leukocytes; Male; Mast Cells; Mice; Mice, Inbred BALB C; Mice, Knockout; Neurokinin-1 Receptor Antagonists; Piperidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Trachea

2003
Role of tachykinin NK1, NK2 and NK3 receptors in the modulation of visceral hypersensitivity in the rat.
    Neuroscience letters, 2003, Nov-13, Volume: 351, Issue:2

    Topics: Animals; Benzamides; Digestive System; Hyperalgesia; Indoles; Injections, Spinal; Isoindoles; Male; Neurokinin-1 Receptor Antagonists; Nociceptors; Oligopeptides; Pain; Pain Threshold; Physical Stimulation; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Tachykinin; Visceral Afferents

2003
Alteration in sensitivity of ionotropic glutamate receptors and tachykinin receptors in spinal cord contribute to development and maintenance of nerve injury-evoked neuropathic pain.
    Neuroscience research, 2006, Volume: 56, Issue:1

    Topics: Alanine; Analgesics; Animals; Behavior, Animal; Benzamides; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Indoles; Isoindoles; Male; N-Methylaspartate; Pain; Pain Measurement; Piperidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Tachykinin; Sciatic Nerve; Spinal Cord; Substance P; Valine

2006
Are biological actions of neurokinin A in the adult brain mediated by a cross-talk between the NK1 and NK2 receptors?
    Neuropharmacology, 2012, Volume: 63, Issue:6

    Topics: Animals; Behavior, Animal; Benzamides; Brain; Dose-Response Relationship, Drug; Grooming; Injections, Intraventricular; Isoindoles; Male; Mice; Mice, Knockout; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Piperidines; Receptor Cross-Talk; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Stereoisomerism; Substance P

2012