sr 48692 has been researched along with sr 142948 in 11 studies
| Studies (sr 48692) | Trials (sr 48692) | Recent Studies (post-2010) (sr 48692) | Studies (sr 142948) | Trials (sr 142948) | Recent Studies (post-2010) (sr 142948) |
|---|---|---|---|---|---|
| 203 | 3 | 36 | 31 | 0 | 18 |
| Protein | Taxonomy | sr 48692 (IC50) | sr 142948 (IC50) |
|---|---|---|---|
| Neurotensin receptor type 1 | Homo sapiens (human) | 0.0037 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (36.36) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bachy, A; Boigegrain, R; Gully, D; Kitabgi, P; Labbé-Jullié, C; Labeeuw, B; Le Fur, G; Maffrand, JP; Oury-Donat, F; Pecceu, F; Poncelet, M; Santucci, V; Soubrié, P; Steinberg, R; Suaud-Chagny, MF; Vita, N | 1 |
| Gendron, L; Giddings, AM; Gilmour, BP; Longpre, JM; Olepu, S; Runyon, SP; Sarret, P; Thomas, JB; Warner, KR; Wiethe, RW; Zhang, Y | 1 |
| Di Fruscia, P; He, Y; Kamenecka, TM; Koenig, M; McDonald, PH; Nieto, A; Tabrizifard, S | 1 |
| Ardecky, RJ; Bai, Y; Barak, LS; Caron, MG; Chung, TDY; Falter, B; Hedrick, MP; Hershberger, P; Jackson, MR; Maloney, P; Peddibhotla, S; Pinkerton, AB; Slosky, LM; Smith, LH; Yamamoto, F | 1 |
| Le Fur, G; Michaud, JC; Nalivaiko, E; Soubrié, P | 1 |
| Alonso, R; Fournier, M; Fréchin, N; Gnanadicom, H; Le Fur, G; Soubrié, P | 1 |
| Aureggi, G; Chalon, P; Croci, T; Ferla, G; Ferrara, P; Fur, GL; Guagnini, F; Gully, D; Maffrand, JP; Manara, L; Mukenge, S; Vita, N | 1 |
| Gueudet, C; Michaud, JC; Soubrié, P | 1 |
| Febvre, M; Ferrara, P; Guillemot, M; Josse, A; Leplatois, P; Loison, G; Vita, N | 1 |
| Greengard, P; Higashi, H; Maeda, H; Matsuyama, S; Nishi, A | 1 |
| Fukui, R; Higashi, H; Matsuyama, S; Nishi, A | 1 |
11 other study(ies) available for sr 48692 and sr 142948
| Article | Year |
|---|---|
Biochemical and pharmacological activities of SR 142948A, a new potent neurotensin receptor antagonist.
Topics: Adamantane; Animals; Axonal Transport; Binding Sites; Brain; Calcium; Cell Line; Cell Membrane; CHO Cells; Corpus Striatum; Cricetinae; Dopamine; Female; Humans; Imidazoles; Inositol Phosphates; Male; Mice; Mice, Inbred Strains; Neurons; Neurotensin; Nucleus Accumbens; Rats; Rats, Inbred Strains; Rats, Sprague-Dawley; Receptors, Neurotensin; Recombinant Proteins; Stereotyped Behavior; Substantia Nigra; Transfection | 1997 |
Identification of 1-({[1-(4-fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazol-3-yl]carbonyl}amino)cyclohexane carboxylic acid as a selective nonpeptide neurotensin receptor type 2 compound.
Topics: Analgesics; Animals; Calcium; CHO Cells; Cricetulus; Cyclohexanecarboxylic Acids; Drug Partial Agonism; Pyrazoles; Radioligand Assay; Rats; Receptors, Neurotensin; Structure-Activity Relationship | 2014 |
The discovery of indole full agonists of the neurotensin receptor 1 (NTSR1).
Topics: Dose-Response Relationship, Drug; Drug Discovery; Humans; Indoles; Molecular Structure; Receptors, Neurotensin; Structure-Activity Relationship | 2014 |
Discovery of β-Arrestin Biased, Orally Bioavailable, and CNS Penetrant Neurotensin Receptor 1 (NTR1) Allosteric Modulators.
Topics: Administration, Oral; Allosteric Regulation; Animals; beta-Arrestins; Biological Availability; Central Nervous System Diseases; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Drug Discovery; Female; Locomotion; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Structure; Quinazolines; Rats; Receptors, Neurotensin; Structure-Activity Relationship | 2019 |
Electrophysiological evidence for putative subtypes of neurotensin receptors in guinea-pig mesencephalic dopaminergic neurons.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Action Potentials; Animals; Dopamine; Guinea Pigs; In Vitro Techniques; Isoquinolines; Kinetics; Membrane Potentials; Mesencephalon; Microelectrodes; Neurons; Neurotensin; Patch-Clamp Techniques; Peptide Fragments; Pyrazoles; Quinolines; Receptors, Neurotensin; Second Messenger Systems; Sulfonamides | 1998 |
Blockade of neurotensin receptors suppresses the dopamine D1/D2 synergism on immediate early gene expression in the rat brain.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Brain Chemistry; Cocaine; DNA-Binding Proteins; Dopamine Agonists; Dopamine Uptake Inhibitors; Early Growth Response Protein 1; Enkephalins; Gene Expression; Genes, Immediate-Early; Immediate-Early Proteins; In Situ Hybridization; Male; Neostriatum; Neurons; Proto-Oncogene Proteins c-fos; Pyrazoles; Quinolines; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Neurotensin; RNA, Messenger; Transcription Factors | 1999 |
In vitro functional evidence of different neurotensin-receptors modulating the motor response of human colonic muscle strips.
Topics: Aged; Colon; Female; Humans; Male; Middle Aged; Muscle, Smooth; Neurotensin; Pyrazoles; Quinolines; Receptors, Neurotensin | 1999 |
Effects of neurotensin receptor antagonists on the firing rate of rat ventral pallidum neurons.
Topics: Action Potentials; Animals; Clozapine; Dopamine Antagonists; Electrophysiology; Globus Pallidus; Haloperidol; Male; Neurons; Pyrazoles; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Neurotensin; Serotonin Antagonists | 2000 |
Neurotensin induces mating in Saccharomyces cerevisiae cells that express human neurotensin receptor type 1 in place of the endogenous pheromone receptor.
Topics: Binding, Competitive; Blotting, Western; Diploidy; Gene Deletion; Gene Expression Regulation, Fungal; Genes, Reporter; Heterotrimeric GTP-Binding Proteins; Humans; Mating Factor; Neurotensin; Peptides; Pheromones; Protein Subunits; Pyrazoles; Quinolines; Receptors, Mating Factor; Receptors, Neurotensin; Receptors, Peptide; Saccharomyces cerevisiae; Signal Transduction; Transcription Factors | 2001 |
Neurotensin regulates DARPP-32 thr34 phosphorylation in neostriatal neurons by activation of dopamine D1-type receptors.
Topics: Animals; Cobalt; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Glutamine; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neostriatum; Nerve Tissue Proteins; Neurons; Neurotensin; Phosphoproteins; Phosphorylation; Piperidines; Pyrazoles; Quinolines; Receptors, Dopamine D1; Receptors, Neurotensin; Signal Transduction; Tetrodotoxin | 2002 |
Regulation of DARPP-32 Thr75 phosphorylation by neurotensin in neostriatal neurons: involvement of glutamate signalling.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthetics, Local; Animals; Benzazepines; Dizocilpine Maleate; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Glutamic Acid; Histamine H1 Antagonists; Immunoblotting; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Neostriatum; Nerve Tissue Proteins; Neurons; Neurotensin; Phosphoproteins; Piperidines; Pyrazoles; Quinolines; Raclopride; Receptors, Neurotensin; Signal Transduction; Tetrodotoxin; Threonine; Time Factors | 2003 |