Page last updated: 2024-09-03

sr 48692 and gamma-aminobutyric acid

sr 48692 has been researched along with gamma-aminobutyric acid in 9 studies

*gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system. [MeSH]

*gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system. [MeSH]

Compound Research Comparison

Studies
(sr 48692)
Trials
(sr 48692)
Recent Studies (post-2010)
(sr 48692)
Studies
(gamma-aminobutyric acid)
Trials
(gamma-aminobutyric acid)
Recent Studies (post-2010) (gamma-aminobutyric acid)
20333640,2151,4239,631

Protein Interaction Comparison

ProteinTaxonomysr 48692 (IC50)gamma-aminobutyric acid (IC50)
Gamma-aminobutyric acid receptor subunit piRattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid type B receptor subunit 2Rattus norvegicus (Norway rat)0.0292
Gamma-aminobutyric acid receptor subunit beta-1Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit deltaRattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit gamma-2Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit alpha-5Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit alpha-3Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit gamma-1Rattus norvegicus (Norway rat)0.0332
Gamma-aminobutyric acid receptor subunit alpha-2Rattus norvegicus (Norway rat)0.0323
Sodium- and chloride-dependent GABA transporter 1Rattus norvegicus (Norway rat)2.152
Gamma-aminobutyric acid receptor subunit alpha-4Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit gamma-3Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit alpha-6Rattus norvegicus (Norway rat)0.0333
Sodium- and chloride-dependent GABA transporter 1Homo sapiens (human)5.2623
Sodium- and chloride-dependent taurine transporterHomo sapiens (human)354
Sodium- and chloride-dependent GABA transporter 2Rattus norvegicus (Norway rat)2.51
Sodium- and chloride-dependent GABA transporter 3Rattus norvegicus (Norway rat)0.02
Sodium- and chloride-dependent GABA transporter 1Mus musculus (house mouse)6.349
Sodium- and chloride-dependent GABA transporter 2Mus musculus (house mouse)7.0795
Sodium- and chloride-dependent GABA transporter 3Mus musculus (house mouse)8.1283
Sodium- and chloride-dependent betaine transporterRattus norvegicus (Norway rat)0.02
Sodium- and chloride-dependent betaine transporterHomo sapiens (human)6.4082
Sodium- and chloride-dependent GABA transporter 3Homo sapiens (human)3.9953
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit beta-3Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit beta-2Rattus norvegicus (Norway rat)0.0333
GABA theta subunitRattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit epsilonRattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid type B receptor subunit 1Rattus norvegicus (Norway rat)0.0292

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (44.44)18.2507
2000's5 (55.56)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chapman, MA; See, RE1
Kombian, SB; Pittman, QJ; Saleh, TM; Zidichouski, JA1
Antonelli, T; Ferraro, L; Fuxe, K; O'Connor, WT; Tanganelli, S1
Antonelli, T; Ferraro, L; Fuxe, K; O'Connor, WT; SoubriƩ, P; Tanganelli, S1
Antonelli, T; Bebe, BW; Fernandez, M; Ferraro, L; Fuxe, K; Glennon, JC; O'Connor, WT; Tanganelli, S; Tomasini, MC1
Bubser, M; Carraway, RE; Deutch, AY; Fadel, J; Petrie, KA; Schmidt, D1
Kalivas, PW; Torregrossa, MM1
Della Corte, L; Mayer, A; Petkova-Kirova, P; Radomirov, R; Rakovska, A; Zaekova, G1
Kawahara, H; Mitchell, VA; Vaughan, CW1

Other Studies

9 other study(ies) available for sr 48692 and gamma-aminobutyric acid

ArticleYear
The neurotensin receptor antagonist SR 48692 decreases extracellular striatal GABA in rats.
    Brain research, 1996, Aug-05, Volume: 729, Issue:1

    Topics: Analysis of Variance; Animals; Corpus Striatum; Female; gamma-Aminobutyric Acid; Glycine; Injections, Subcutaneous; Microdialysis; Pyrazoles; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Neurotensin

1996
Cholecystokinin and neurotensin inversely modulate excitatory synaptic transmission in the parabrachial nucleus in vitro.
    Neuroscience, 1997, Volume: 77, Issue:1

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Benzodiazepinones; Cholecystokinin; Devazepide; Electric Conductivity; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Hormone Antagonists; Interneurons; N-Methylaspartate; Neural Inhibition; Neurons, Afferent; Neurotensin; Patch-Clamp Techniques; Phenylurea Compounds; Pons; Pyrazoles; Quinolines; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin A; Receptors, Cholecystokinin; Receptors, Neurotensin; Synaptic Transmission; Tetrodotoxin

1997
Differential effects of intrastriatal neurotensin(1-13) and neurotensin(8-13) on striatal dopamine and pallidal GABA release. A dual-probe microdialysis study in the awake rat.
    The European journal of neuroscience, 1997, Volume: 9, Issue:9

    Topics: Animals; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Globus Pallidus; Male; Microdialysis; Neurotensin; Peptide Fragments; Perfusion; Pergolide; Pyrazoles; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Neurotensin

1997
The striatal neurotensin receptor modulates striatal and pallidal glutamate and GABA release: functional evidence for a pallidal glutamate-GABA interaction via the pallidal-subthalamic nucleus loop.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Sep-01, Volume: 18, Issue:17

    Topics: Animals; Bicuculline; Corpus Striatum; GABA Antagonists; gamma-Aminobutyric Acid; Globus Pallidus; Glutamic Acid; Injections; Male; Microdialysis; Perfusion; Pyrazoles; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Neurotensin; Synaptic Transmission; Thalamic Nuclei

1998
Nigral neurotensin receptor regulation of nigral glutamate and nigroventral thalamic GABA transmission: a dual-probe microdialysis study in intact conscious rat brain.
    Neuroscience, 2001, Volume: 102, Issue:1

    Topics: Animals; Consciousness; Dopamine Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Microdialysis; Neural Pathways; Neurons; Neurotensin; Peptide Fragments; Pyrazoles; Quinolines; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, Neurotensin; Substantia Nigra; Synaptic Transmission; Tetrodotoxin; Ventral Thalamic Nuclei

2001
Neurotensin activates GABAergic interneurons in the prefrontal cortex.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Feb-16, Volume: 25, Issue:7

    Topics: Animals; Axons; Dopamine; Dopamine Agonists; gamma-Aminobutyric Acid; Interneurons; Male; Microdialysis; Neurotensin; Parvalbumins; Prefrontal Cortex; Pyrazoles; Quinolines; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Neurotensin; Schizophrenia; Tetrodotoxin

2005
Neurotensin in the ventral pallidum increases extracellular gamma-aminobutyric acid and differentially affects cue- and cocaine-primed reinstatement.
    The Journal of pharmacology and experimental therapeutics, 2008, Volume: 325, Issue:2

    Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; gamma-Aminobutyric Acid; Male; Motor Activity; Neurotensin; Peptide Fragments; Pyrazoles; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Neurotensin; Self Administration

2008
Neurotensin modulation of acetylcholine, GABA, and aspartate release from rat prefrontal cortex studied in vivo with microdialysis.
    Brain research bulletin, 2008, Sep-30, Volume: 77, Issue:2-3

    Topics: Acetylcholine; Animals; Aspartic Acid; gamma-Aminobutyric Acid; Glutamic Acid; Male; Microdialysis; Motor Activity; Neurotensin; Prefrontal Cortex; Pyrazoles; Quinolines; Rats; Rats, Wistar; Receptors, Neurotensin; Sodium Channel Blockers; Taurine; Tetrodotoxin

2008
Neurotensin inhibition of GABAergic transmission via mGluR-induced endocannabinoid signalling in rat periaqueductal grey.
    The Journal of physiology, 2009, Jun-01, Volume: 587, Issue:Pt 11

    Topics: Adamantane; Animals; Cannabinoid Receptor Modulators; Endocannabinoids; Excitatory Amino Acid Antagonists; Female; gamma-Aminobutyric Acid; Imidazoles; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Miniature Postsynaptic Potentials; Neural Inhibition; Neurons; Neurotensin; Pain; Periaqueductal Gray; Piperidines; Presynaptic Terminals; Pyrazoles; Pyridines; Quinolines; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, Neurotensin; Synaptic Transmission; Tetrodotoxin; Time Factors

2009