sr 48692 has been researched along with cocaine in 6 studies
| Studies (sr 48692) | Trials (sr 48692) | Recent Studies (post-2010) (sr 48692) | Studies (cocaine) | Trials (cocaine) | Recent Studies (post-2010) (cocaine) |
|---|---|---|---|---|---|
| 203 | 3 | 36 | 32,461 | 1,096 | 9,400 |
| Protein | Taxonomy | sr 48692 (IC50) | cocaine (IC50) |
|---|---|---|---|
| Amyloid-beta precursor protein | Homo sapiens (human) | 0.338 | |
| Fatty acid-binding protein, heart | Homo sapiens (human) | 0.367 | |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | 0.0855 | |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 0.0855 | |
| D | Rattus norvegicus (Norway rat) | 5.7544 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 5.7544 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 5.7544 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 5.7544 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 1.2861 | |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | 0.4321 | |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | 0.0855 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 0.5442 | |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | 0.8885 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 0.3796 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 5.541 | |
| Sodium-dependent dopamine transporter | Mus musculus (house mouse) | 0.2 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 1.05 | |
| Transporter | Rattus norvegicus (Norway rat) | 3.2277 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Elsworth, JD; Horger, BA; Roth, RH; Taylor, JR | 1 |
| Betancur, C; Cabrera, R; de Kloet, ER; Pélaprat, D; Rostène, W | 1 |
| Alonso, R; Fournier, M; Fréchin, N; Gnanadicom, H; Le Fur, G; Soubrié, P | 1 |
| Bérod, A; Espinosa, JM; Felszeghy, K; Pélaprat, D; Rostène, W; Scarna, H | 1 |
| Kalivas, PW; Torregrossa, MM | 1 |
| Cajigas, MH; Cruz, D; Falcón, E; Iturbe, MC; Maldonado-Vlaar, CS; Negrón, A; Ramos-Ortolaza, DL | 1 |
6 other study(ies) available for sr 48692 and cocaine
| Article | Year |
|---|---|
Preexposure to, but not cotreatment with, the neurotensin antagonist SR 48692 delays the development of cocaine sensitization.
Topics: Animals; Cocaine; Male; Motor Activity; Pyrazoles; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Neurotensin; Time Factors | 1994 |
Role of endogenous neurotensin in the behavioral and neuroendocrine effects of cocaine.
Topics: Animals; Cocaine; Corticosterone; Dopamine Uptake Inhibitors; Hypothalamo-Hypophyseal System; Male; Motor Activity; Neurotensin; Pituitary-Adrenal System; Pyrazoles; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Neurotensin; Stereotyped Behavior | 1998 |
Blockade of neurotensin receptors suppresses the dopamine D1/D2 synergism on immediate early gene expression in the rat brain.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Brain Chemistry; Cocaine; DNA-Binding Proteins; Dopamine Agonists; Dopamine Uptake Inhibitors; Early Growth Response Protein 1; Enkephalins; Gene Expression; Genes, Immediate-Early; Immediate-Early Proteins; In Situ Hybridization; Male; Neostriatum; Neurons; Proto-Oncogene Proteins c-fos; Pyrazoles; Quinolines; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Neurotensin; RNA, Messenger; Transcription Factors | 1999 |
Neurotensin receptor antagonist administered during cocaine withdrawal decreases locomotor sensitization and conditioned place preference.
Topics: Analysis of Variance; Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Drug Administration Schedule; Male; Motor Activity; Pyrazoles; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Neurotensin; Substance Withdrawal Syndrome; Time Factors | 2007 |
Neurotensin in the ventral pallidum increases extracellular gamma-aminobutyric acid and differentially affects cue- and cocaine-primed reinstatement.
Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; gamma-Aminobutyric Acid; Male; Motor Activity; Neurotensin; Peptide Fragments; Pyrazoles; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Neurotensin; Self Administration | 2008 |
Intra-accumbens shell injections of SR48692 enhanced cocaine self-administration intake in rats exposed to an environmentally-elicited reinstatement paradigm.
Topics: Animals; Behavior, Animal; Central Nervous System Agents; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Environment; Learning; Male; Neurotensin; Nucleus Accumbens; Prefrontal Cortex; Psychomotor Performance; Pyrazoles; Quinolines; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Neurotensin; Self Administration | 2009 |