Page last updated: 2024-09-03

sr 48692 and 6-methyl-2-(phenylethynyl)pyridine

sr 48692 has been researched along with 6-methyl-2-(phenylethynyl)pyridine in 2 studies

Compound Research Comparison

Studies (sr 48692)	Trials (sr 48692)	Recent Studies (post-2010) (sr 48692)	Studies (6-methyl-2-(phenylethynyl)pyridine)	Trials (6-methyl-2-(phenylethynyl)pyridine)	Recent Studies (post-2010) (6-methyl-2-(phenylethynyl)pyridine)
203	3	36	543	0	185

Protein Interaction Comparison

Protein	Taxonomy	6-methyl-2-(phenylethynyl)pyridine (IC50)
Luciferin 4-monooxygenase	Photinus pyralis (common eastern firefly)	6.2333
Metabotropic glutamate receptor 5	Rattus norvegicus (Norway rat)	0.0129
Metabotropic glutamate receptor 5	Homo sapiens (human)	0.0199
Amine oxidase [flavin-containing] A	Mus musculus (house mouse)	8

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ	1
Kawahara, H; Mitchell, VA; Vaughan, CW	1

Other Studies

2 other study(ies) available for sr 48692 and 6-methyl-2-(phenylethynyl)pyridine

Article	Year
Identification of potent Yes1 kinase inhibitors using a library screening approach. Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15 Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship	2013
Neurotensin inhibition of GABAergic transmission via mGluR-induced endocannabinoid signalling in rat periaqueductal grey. The Journal of physiology, 2009, Jun-01, Volume: 587, Issue:Pt 11 Topics: Adamantane; Animals; Cannabinoid Receptor Modulators; Endocannabinoids; Excitatory Amino Acid Antagonists; Female; gamma-Aminobutyric Acid; Imidazoles; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Miniature Postsynaptic Potentials; Neural Inhibition; Neurons; Neurotensin; Pain; Periaqueductal Gray; Piperidines; Presynaptic Terminals; Pyrazoles; Pyridines; Quinolines; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, Neurotensin; Synaptic Transmission; Tetrodotoxin; Time Factors	2009

Article

Year

Identification of potent Yes1 kinase inhibitors using a library screening approach.

Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013

Neurotensin inhibition of GABAergic transmission via mGluR-induced endocannabinoid signalling in rat periaqueductal grey.

The Journal of physiology, 2009, Jun-01, Volume: 587, Issue:Pt 11

Topics: Adamantane; Animals; Cannabinoid Receptor Modulators; Endocannabinoids; Excitatory Amino Acid Antagonists; Female; gamma-Aminobutyric Acid; Imidazoles; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Miniature Postsynaptic Potentials; Neural Inhibition; Neurons; Neurotensin; Pain; Periaqueductal Gray; Piperidines; Presynaptic Terminals; Pyrazoles; Pyridines; Quinolines; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, Neurotensin; Synaptic Transmission; Tetrodotoxin; Time Factors

2009