Page last updated: 2024-09-03

sr 46349b and prazosin

sr 46349b has been researched along with prazosin in 4 studies

Compound Research Comparison

Studies
(sr 46349b)
Trials
(sr 46349b)
Recent Studies (post-2010)
(sr 46349b)
Studies
(prazosin)
Trials
(prazosin)
Recent Studies (post-2010) (prazosin)
51177,914713682

Protein Interaction Comparison

ProteinTaxonomysr 46349b (IC50)prazosin (IC50)
Solute carrier family 22 member 1 Homo sapiens (human)5.87
Interstitial collagenaseHomo sapiens (human)4.036
Alpha-2A adrenergic receptorHomo sapiens (human)2.638
Matrix metalloproteinase-9Homo sapiens (human)6.963
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)0.0008
Ribosyldihydronicotinamide dehydrogenase [quinone]Homo sapiens (human)0.0078
Alpha-2B adrenergic receptorHomo sapiens (human)0.29
Alpha-2C adrenergic receptorHomo sapiens (human)0.647
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)0.0008
Alpha-1D adrenergic receptorHomo sapiens (human)0.0007
Bromodomain-containing protein 2Homo sapiens (human)0.0009
Alpha-1A adrenergic receptorHomo sapiens (human)0.0006
Alpha-1B adrenergic receptorHomo sapiens (human)0.0006
5-hydroxytryptamine receptor 2BHomo sapiens (human)4.118
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.0008
5-hydroxytryptamine receptor 7Cavia porcellus (domestic guinea pig)9.9
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)1.5849
Multidrug and toxin extrusion protein 1Homo sapiens (human)1.6

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Auclair, A; Cotecchia, S; Drouin, C; Glowinski, J; Tassin, JP1
Bourin, M; Dailly, E; Hascoët, M; Masse, F1
Blanc, G; Gingrich, J; Godeheu, G; Lanteri, C; Salomon, L; Tassin, JP1
Doucet, EL; Godeheu, G; Hernández Vallejo, SJ; Houades, V; Lanteri, C; Salomon, L; Tassin, JP; Torrens, Y1

Other Studies

4 other study(ies) available for sr 46349b and prazosin

ArticleYear
5-HT2A and alpha1b-adrenergic receptors entirely mediate dopamine release, locomotor response and behavioural sensitization to opiates and psychostimulants.
    The European journal of neuroscience, 2004, Volume: 20, Issue:11

    Topics: Adrenergic alpha-Antagonists; Anesthetics, Local; Animals; Behavior, Animal; Brain Chemistry; Central Nervous System Stimulants; Cocaine; Corpus Striatum; Dextroamphetamine; Dopamine; Drug Administration Schedule; Drug Interactions; Fluorobenzenes; Male; Mice; Mice, Knockout; Microdialysis; Motor Activity; Narcotics; Phenols; Prazosin; Receptor, Serotonin, 5-HT2A; Receptors, Adrenergic, alpha-1; Serotonin Antagonists; Time Factors

2004
Anxiolytic-like effect of milnacipran in the four-plate test in mice: mechanism of action.
    Pharmacology, biochemistry, and behavior, 2005, Volume: 81, Issue:3

    Topics: Alprazolam; Animals; Anti-Anxiety Agents; Behavior, Animal; Benzylamines; Brain; Cyclopropanes; Dopamine; Dose-Response Relationship, Drug; Fenclonine; Flumazenil; Fluorobenzenes; Idazoxan; Indoles; Ketanserin; Male; Mice; Milnacipran; Motor Activity; Neurotransmitter Uptake Inhibitors; Norepinephrine; Phenols; Prazosin; Punishment; Pyridines; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists

2005
Paradoxical constitutive behavioral sensitization to amphetamine in mice lacking 5-HT2A receptors.
    Psychopharmacology, 2007, Volume: 194, Issue:1

    Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Behavior, Animal; Central Nervous System Stimulants; Dextroamphetamine; Dose-Response Relationship, Drug; Fluorobenzenes; Histamine H2 Antagonists; Mice; Mice, Knockout; Motor Activity; Phenols; Prazosin; Receptor, Serotonin, 5-HT2A

2007
Inhibition of monoamine oxidases desensitizes 5-HT1A autoreceptors and allows nicotine to induce a neurochemical and behavioral sensitization.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009, Jan-28, Volume: 29, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoreceptors; Behavior, Animal; Brain Chemistry; Drug Combinations; Fluorobenzenes; Male; Mice; Mice, Inbred C57BL; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Nicotine; Nicotinic Agonists; Phenols; Piperazines; Prazosin; Pyridines; Raphe Nuclei; Receptor, Serotonin, 5-HT1A; Serotonin Antagonists; Serotonin Receptor Agonists; Tranylcypromine

2009