sr 46349b has been researched along with mdl 100907 in 14 studies
| Studies (sr 46349b) | Trials (sr 46349b) | Recent Studies (post-2010) (sr 46349b) | Studies (mdl 100907) | Trials (mdl 100907) | Recent Studies (post-2010) (mdl 100907) |
|---|---|---|---|---|---|
| 51 | 1 | 7 | 1,241 | 65 | 539 |
| Protein | Taxonomy | sr 46349b (IC50) | mdl 100907 (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.0048 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 7 (50.00) | 29.6817 |
| 2010's | 6 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Marcoli, M; Maura, G; Raiteri, M; Tortarolo, M | 1 |
| Alboszta, AR; Bonaccorso, S; Dai, J; Ichikawa, J; Li, Z; Meltzer, HY | 1 |
| Gray, JA; Joseph, MH; McDonald, LM; Moran, PM; Stephenson, JD; Vythelingum, GN | 1 |
| Auclair, A; Blanc, G; Glowinski, J; Tassin, JP | 1 |
| Bourin, M; Dailly, E; Hascoët, M; Masse, F | 1 |
| Miyamoto, M; Terao, A | 1 |
| Blessing, WW; Nalivaiko, E; Ootsuka, Y | 1 |
| Baumert, M; Beig, MI; Day, TA; Nalivaiko, E; Walker, FR | 1 |
| Herth, MM; Knudsen, GM; Kramer, V; Palner, M; Rösch, F; Santini, MA | 1 |
| Lanfumey, L; Maldonado, R; Orejarena, MJ; Robledo, P | 1 |
| Arnt, J; Ebdrup, BH; Glenthøj, B; Rasmussen, H | 1 |
| Alonso, R; Avenet, P; Beeské, S; Decobert, M; Françon, D; Griebel, G; Jacquet, A; Laufrais, C | 1 |
| Dougherty, JP; Oristaglio, J | 1 |
| Ootsuka, Y; Sinh, V | 1 |
2 review(s) available for sr 46349b and mdl 100907
| Article | Year |
|---|---|
[Recent and potential drugs for treatment of insomnia].
Topics: Animals; Azabicyclo Compounds; Benzodiazepines; Diphenhydramine; Drug Design; Fluorobenzenes; GABA-A Receptor Agonists; Histamine H1 Antagonists; Humans; Hypnotics and Sedatives; Indenes; Orexin Receptors; Phenols; Piperazines; Pyridines; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Serotonin 5-HT2 Receptor Antagonists; Sleep Initiation and Maintenance Disorders; Thiophenes; Zolpidem | 2007 |
Serotonin 2A receptor antagonists for treatment of schizophrenia.
Topics: Antipsychotic Agents; Brain; Fluorobenzenes; Humans; Phenols; Piperidines; Positron-Emission Tomography; Receptor, Serotonin, 5-HT2A; Schizophrenia; Serotonin 5-HT2 Receptor Antagonists; Urea | 2011 |
12 other study(ies) available for sr 46349b and mdl 100907
| Article | Year |
|---|---|
Serotonin inhibition of the NMDA receptor/nitric oxide/cyclic GMP pathway in rat cerebellum: involvement of 5-hydroxytryptamine2C receptors.
Topics: Adrenergic alpha-Antagonists; Animals; Cerebellum; Cyclic GMP; Excitatory Amino Acid Agonists; Fluorobenzenes; Indoles; Male; N-Methylaspartate; Nitric Oxide; Organ Culture Techniques; Phenols; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Urea; Yohimbine | 1997 |
SR46349-B, a 5-HT(2A/2C) receptor antagonist, potentiates haloperidol-induced dopamine release in rat medial prefrontal cortex and nucleus accumbens.
Topics: Analysis of Variance; Animals; Dopamine; Dopamine Antagonists; Drug Synergism; Fluorobenzenes; Haloperidol; Male; Nucleus Accumbens; Phenols; Piperidines; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin Antagonists; Telencephalon | 2002 |
Enhancement of latent inhibition by two 5-HT2A receptor antagonists only when given at both pre-exposure and conditioning.
Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Amphetamine; Analysis of Variance; Animals; Association Learning; Behavior, Animal; Central Nervous System Stimulants; Conditioning, Classical; Dose-Response Relationship, Drug; Drug Interactions; Fluorobenzenes; Inhibition, Psychological; Male; Phencyclidine; Phenols; Quinolines; Rats; Rats, Sprague-Dawley; Serotonin 5-HT2 Receptor Antagonists; Serotonin Receptor Agonists; Stereotyped Behavior | 2003 |
Role of serotonin 2A receptors in the D-amphetamine-induced release of dopamine: comparison with previous data on alpha1b-adrenergic receptors.
Topics: Animals; Dextroamphetamine; Dopamine; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Antagonism; Extracellular Fluid; Fluorobenzenes; Male; Microdialysis; Motor Activity; Neurons; Nucleus Accumbens; Phenols; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Adrenergic, alpha-1; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Ventral Tegmental Area | 2004 |
Anxiolytic-like effect of milnacipran in the four-plate test in mice: mechanism of action.
Topics: Alprazolam; Animals; Anti-Anxiety Agents; Behavior, Animal; Benzylamines; Brain; Cyclopropanes; Dopamine; Dose-Response Relationship, Drug; Fenclonine; Flumazenil; Fluorobenzenes; Idazoxan; Indoles; Ketanserin; Male; Mice; Milnacipran; Motor Activity; Neurotransmitter Uptake Inhibitors; Norepinephrine; Phenols; Prazosin; Punishment; Pyridines; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists | 2005 |
Selective blockade of 5-HT2A receptors attenuates the increased temperature response in brown adipose tissue to restraint stress in rats.
Topics: Adipose Tissue, Brown; Animals; Body Temperature Regulation; Fluorobenzenes; Male; Phenols; Rats; Rats, Wistar; Restraint, Physical; Serotonin 5-HT2 Receptor Antagonists; Stress, Psychological; Tachycardia; Tail; Vasoconstriction | 2008 |
Blockade of 5-HT2A receptors suppresses hyperthermic but not cardiovascular responses to psychosocial stress in rats.
Topics: Analysis of Variance; Animals; Blood Pressure; Body Temperature; Cardiovascular System; Electrocardiography; Fever; Fluorobenzenes; Heart Rate; Male; Phenols; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Social Dominance; Stress, Psychological; Tachycardia | 2009 |
Structural combination of established 5-HT(2A) receptor ligands: new aspects of the binding mode.
Topics: Binding, Competitive; Combinatorial Chemistry Techniques; Fluorobenzenes; Hydrophobic and Hydrophilic Interactions; Ketanserin; Ligands; Phenols; Piperidines; Protein Binding; Pyridines; Receptor, Serotonin, 5-HT2A; Serotonin 5-HT2 Receptor Antagonists | 2010 |
Involvement of 5-HT2A receptors in MDMA reinforcement and cue-induced reinstatement of MDMA-seeking behaviour.
Topics: Animals; Behavior, Addictive; Cues; Dopamine; Dose-Response Relationship, Drug; Extinction, Psychological; Female; Fluorobenzenes; Locomotion; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methyl-3,4-methylenedioxyamphetamine; Norepinephrine; Nucleus Accumbens; Phenols; Prefrontal Cortex; Receptor, Serotonin, 5-HT2A; Reinforcement, Psychology; Self Administration; Serotonin; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists | 2011 |
Further evidence for the sleep-promoting effects of 5-HT₂A receptor antagonists and demonstration of synergistic effects with the hypnotic, zolpidem in rats.
Topics: Animals; Dose-Response Relationship, Drug; Drug Synergism; Fluorobenzenes; Hypnotics and Sedatives; Male; Phenols; Piperidines; Pyridines; Rats; Serotonin Antagonists; Sleep Stages; Wakefulness; Zolpidem | 2013 |
Chronic treatment with the serotonin 2A/2C receptor antagonist SR 46349B enhances the retention and efficiency of rule-guided behavior in mice.
Topics: Animals; Behavior, Animal; Fluorobenzenes; Male; Maze Learning; Memory; Mice; Phenols; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Reversal Learning; Serotonin 5-HT2 Receptor Antagonists | 2013 |
Blockade of 5-HT2A receptors inhibits emotional hyperthermia in mice.
Topics: Animals; Fever; Fluorobenzenes; Heart Rate; Male; Mice; Mice, Inbred C57BL; Motor Activity; Phenols; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Stress, Psychological | 2019 |