Compounds > sr 33557
Page last updated: 2024-09-03

sr 33557 and nifedipine

sr 33557 has been researched along with nifedipine in 5 studies

Compound Research Comparison

Studies
(sr 33557)		Trials
(sr 33557)		Recent Studies (post-2010)
(sr 33557)		Studies
(nifedipine)		Trials
(nifedipine)		Recent Studies (post-2010) (nifedipine)
503116,0242,4961,505

Protein Interaction Comparison

ProteinTaxonomysr 33557 (IC50)nifedipine (IC50)
perilipin-5Homo sapiens (human)7.133
perilipin-1Homo sapiens (human)9.619
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform aHomo sapiens (human)8.376
Voltage-dependent L-type calcium channel subunit alpha-1CCavia porcellus (domestic guinea pig)0.0429
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)0.035
Cytochrome P450 1A2Homo sapiens (human)0.3
Cytochrome P450 3A4Homo sapiens (human)10
Adenosine receptor A3Homo sapiens (human)7.214
Cytochrome P450 2C9 Homo sapiens (human)3.06
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)10
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)7.214
Voltage-dependent L-type calcium channel subunit alpha-1CRattus norvegicus (Norway rat)0.0385
Potassium voltage-gated channel subfamily A member 5Homo sapiens (human)6.1
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Rattus norvegicus (Norway rat)1.12
Adenosine receptor A1Homo sapiens (human)7.701
3-oxo-5-alpha-steroid 4-dehydrogenase 2Rattus norvegicus (Norway rat)1.12
C-C chemokine receptor type 2Homo sapiens (human)2.191
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)7.214
Cytochrome P450 2J2Homo sapiens (human)3.06
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)0.4733
Voltage-dependent L-type calcium channel subunit alpha-1CMus musculus (house mouse)1.2
Voltage-dependent L-type calcium channel subunit alpha-1SMus musculus (house mouse)1.2
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)0.035
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)0.0394
Myosin light chain kinase, smooth muscleHomo sapiens (human)2.02
Potassium channel subfamily K member 2 Bos taurus (cattle)8.2
Indoleamine 2,3-dioxygenase 2Mus musculus (house mouse)1.5
Voltage-dependent L-type calcium channel subunit alpha-1DMus musculus (house mouse)1.2
Voltage-dependent L-type calcium channel subunit alpha-1FMus musculus (house mouse)1.2

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (80.00)18.2507
2000's0 (0.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chatelain, P; Clinet, M; Gubin, J; Lucchetti, J; Mahaux, J; Nisato, D; Polster, P; Rosseels, G1
Clinet, M; de Vogelaer, H; Gubin, J; Houben, C; Inion, H; Lucchetti, J; Mahaux, J; Peiren, M; Polster, P; Rosseels, G1
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B1
Chatelain, P; Christophe, B; Clinet, M; Manning, AS; Polster, P1
Garcia, L; Marty, I; Parrish, E; Rieger, F; Romey, G; Seigneurin-Venin, S; Villaz, M1

Other Studies

5 other study(ies) available for sr 33557 and nifedipine

ArticleYear
A novel class of calcium-entry blockers: the 1[[4-(aminoalkoxy)phenyl]sulfonyl]indolizines.
    Journal of medicinal chemistry, 1992, Mar-20, Volume: 35, Issue:6

    Topics: Animals; Binding Sites; Brain; Calcium Channel Blockers; Guinea Pigs; Indolizines; Male; Phenethylamines; Rats; Rats, Inbred Strains; Structure-Activity Relationship

1992
Novel heterocyclic analogues of the new potent class of calcium entry blockers: 1-[[4-(aminoalkoxy)phenyl]sulfonyl]indolizines.
    Journal of medicinal chemistry, 1993, May-14, Volume: 36, Issue:10

    Topics: Animals; Calcium Channel Blockers; Cerebral Cortex; Guinea Pigs; Heterocyclic Compounds; Indolizines; Male; Muscle, Smooth, Vascular; Phenethylamines; Rats; Rats, Wistar; Structure-Activity Relationship

1993
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
    Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10

    Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers

2012
In vitro characterization of a novel Ca2+ entry blocker: SR 33805.
    European journal of pharmacology, 1993, Aug-15, Volume: 246, Issue:3

    Topics: Animals; Binding, Competitive; Calcium Channel Blockers; Diltiazem; Heart Rate; In Vitro Techniques; Indoles; Indolizines; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Myocardium; Nifedipine; Phenethylamines; Rabbits; Radioligand Assay; Rats; Rats, Wistar; Sarcolemma; Sulfones; Verapamil

1993
Involvement of the dihydropyridine receptor and internal Ca2+ stores in myoblast fusion.
    Experimental cell research, 1996, Mar-15, Volume: 223, Issue:2

    Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Calcium-Transporting ATPases; Cell Fusion; Cell Line; Creatine Kinase; Enzyme Inhibitors; Indolizines; Ion Channel Gating; Muscle Fibers, Skeletal; Muscle Proteins; Muscles; Nifedipine; Phenethylamines; Rats; Ryanodine; Ryanodine Receptor Calcium Release Channel; Terpenes; Thapsigargin

1996