Page last updated: 2024-09-02

sr 140333 and vofopitant

sr 140333 has been researched along with vofopitant in 3 studies

Compound Research Comparison

Studies
(sr 140333)
Trials
(sr 140333)
Recent Studies (post-2010)
(sr 140333)
Studies
(vofopitant)
Trials
(vofopitant)
Recent Studies (post-2010) (vofopitant)
23601271812

Protein Interaction Comparison

ProteinTaxonomysr 140333 (IC50)vofopitant (IC50)
Substance-P receptorHomo sapiens (human)0.0001

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bentley, G; Carlson, EJ; Cascieri, MA; Chicchi, GG; Di Salvo, J; Gould, SL; Hill, A; Kilburn, R; Kurtz, MM; Mills, SG; Rupniak, NM; Shepheard, S; Swain, C; Tsao, KL; Williams, AR1
Boyce, S; Clarke, D; Fisher, A; O'Connor, D; Pike, A; Rupniak, NM; Watt, A1
Beaujouan, JC; Glowinski, J; Jabourian, M; Kemel, ML; Pérez, S; Soubrié, P1

Other Studies

3 other study(ies) available for sr 140333 and vofopitant

ArticleYear
Comparison of the functional blockade of rat substance P (NK1) receptors by GR205171, RP67580, SR140333 and NKP-608.
    Neuropharmacology, 2003, Volume: 45, Issue:2

    Topics: Animals; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Female; Gerbillinae; Humans; Indoles; Isoindoles; Male; Neurokinin-1 Receptor Antagonists; Piperidines; Quinolines; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Tetrazoles; Tumor Cells, Cultured

2003
P-Glycoprotein efflux reduces the brain concentration of the substance P (NK1 receptor) antagonists SR140333 and GR205171: a comparative study using mdr1a-/- and mdr1a+/+ mice.
    Behavioural pharmacology, 2003, Volume: 14, Issue:5-6

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain Chemistry; Disease Models, Animal; Genes, MDR; Male; Mice; Mice, Knockout; Neurokinin-1 Receptor Antagonists; Piperidines; Quinuclidines; Stereoisomerism; Tetrazoles

2003
The new neurokinin 1-sensitive receptor mediates the facilitation by endogenous tachykinins of the NMDA-evoked release of acetylcholine after suppression of dopaminergic transmission in the matrix of the rat striatum.
    Journal of neurochemistry, 2003, Volume: 87, Issue:2

    Topics: Acetylcholine; alpha-Methyltyrosine; Animals; Corpus Striatum; Dopamine; In Vitro Techniques; Male; Morpholines; N-Methylaspartate; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Perfusion; Piperidines; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Substance P; Synaptic Transmission; Tachykinins; Tetrazoles

2003