sr 140333 has been researched along with vofopitant in 3 studies
| Studies (sr 140333) | Trials (sr 140333) | Recent Studies (post-2010) (sr 140333) | Studies (vofopitant) | Trials (vofopitant) | Recent Studies (post-2010) (vofopitant) |
|---|---|---|---|---|---|
| 236 | 0 | 12 | 71 | 8 | 12 |
| Protein | Taxonomy | sr 140333 (IC50) | vofopitant (IC50) |
|---|---|---|---|
| Substance-P receptor | Homo sapiens (human) | 0.0001 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bentley, G; Carlson, EJ; Cascieri, MA; Chicchi, GG; Di Salvo, J; Gould, SL; Hill, A; Kilburn, R; Kurtz, MM; Mills, SG; Rupniak, NM; Shepheard, S; Swain, C; Tsao, KL; Williams, AR | 1 |
| Boyce, S; Clarke, D; Fisher, A; O'Connor, D; Pike, A; Rupniak, NM; Watt, A | 1 |
| Beaujouan, JC; Glowinski, J; Jabourian, M; Kemel, ML; Pérez, S; Soubrié, P | 1 |
3 other study(ies) available for sr 140333 and vofopitant
| Article | Year |
|---|---|
Comparison of the functional blockade of rat substance P (NK1) receptors by GR205171, RP67580, SR140333 and NKP-608.
Topics: Animals; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Female; Gerbillinae; Humans; Indoles; Isoindoles; Male; Neurokinin-1 Receptor Antagonists; Piperidines; Quinolines; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Tetrazoles; Tumor Cells, Cultured | 2003 |
P-Glycoprotein efflux reduces the brain concentration of the substance P (NK1 receptor) antagonists SR140333 and GR205171: a comparative study using mdr1a-/- and mdr1a+/+ mice.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain Chemistry; Disease Models, Animal; Genes, MDR; Male; Mice; Mice, Knockout; Neurokinin-1 Receptor Antagonists; Piperidines; Quinuclidines; Stereoisomerism; Tetrazoles | 2003 |
The new neurokinin 1-sensitive receptor mediates the facilitation by endogenous tachykinins of the NMDA-evoked release of acetylcholine after suppression of dopaminergic transmission in the matrix of the rat striatum.
Topics: Acetylcholine; alpha-Methyltyrosine; Animals; Corpus Striatum; Dopamine; In Vitro Techniques; Male; Morpholines; N-Methylaspartate; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Perfusion; Piperidines; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Substance P; Synaptic Transmission; Tachykinins; Tetrazoles | 2003 |