sr 140333 has been researched along with atropine in 21 studies
| Studies (sr 140333) | Trials (sr 140333) | Recent Studies (post-2010) (sr 140333) | Studies (atropine) | Trials (atropine) | Recent Studies (post-2010) (atropine) |
|---|---|---|---|---|---|
| 236 | 0 | 12 | 26,711 | 1,259 | 1,697 |
| Protein | Taxonomy | sr 140333 (IC50) | atropine (IC50) |
|---|---|---|---|
| cystic fibrosis transmembrane conductance regulator | Homo sapiens (human) | 21.41 | |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 1.012 | |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 0.0067 | |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 0.0007 | |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | 0.001 | |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | 0.001 | |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | 0.001 | |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | 0.001 | |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | 0.0009 | |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | 0.001 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 0.0015 | |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | 0.0021 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 1.354 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 1.012 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (47.62) | 18.2507 |
| 2000's | 10 (47.62) | 29.6817 |
| 2010's | 1 (4.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Croci, T; Emonds-Alt, X; Le Fur, G; Manara, L | 1 |
| Giuliani, S; Maggi, CA; Zagorodnyuk, V | 2 |
| Maggi, CA; Meini, S | 1 |
| Giuliani, S; Maggi, CA | 1 |
| Giorgio, RD; Giuliani, S; Lecci, A; Maggi, CA; Tramontana, M | 1 |
| Barthó, L; Heinemann, A; Holzer, P; Lippe, IT | 1 |
| Borrelli, F; Capasso, F; Izzo, AA; Mascolo, N | 1 |
| Chen, JS; Tian, J; Wei, EQ; Zhang, WP | 1 |
| Buljubasich, S; Lau, WA; Pennefather, JN; Ventura, S | 1 |
| Kouznetsova, M; Nistri, A | 1 |
| Gustafsson, LE; Olgart, C; Wiklund, NP | 1 |
| Crema, A; Crema, F; de Ponti, F; Frigo, G; Moro, E; Nardelli, G | 1 |
| De Swert, KO; Joos, GF; Leclere, PG; Lefebvre, RA; Pauwels, RA; Tournoy, KG | 1 |
| Aggio, A; Ciccocioppo, R; Loreto, MF; Onori, L; Taddei, G; Tonini, M; Vicini, R | 1 |
| Amadesi, S; Bardella, E; Bunnett, NW; De Giorgio, R; Figueroa, CD; Geppetti, P; Harrison, S; Maggiore, B; Navarra, G; Poblete, MT; Schmidlin, F; Tognetto, M; Trevisani, M; Turini, A | 1 |
| Capparelli, A; Mulè, F; Pizzuti, R; Vergnolle, N | 1 |
| Chen, Q; Fu, CY; Kong, ZQ; Long, Y; Wang, R | 1 |
| Bornstein, JC; Larsson, MH; Lindström, E; Sapnara, M; Sjövall, H; Svensson, DJ; Thomas, EA | 1 |
| Chen, Q; Fu, CY; Kong, ZQ; Wang, R | 1 |
| Colucci, M; Di Giannuario, A; Maione, F; Mascolo, N; Mastriota, M; Palmery, M; Perretti, M; Pieretti, S; Severini, C | 1 |
21 other study(ies) available for sr 140333 and atropine
| Article | Year |
|---|---|
In vitro characterization of the non-peptide tachykinin NK1 and NK2-receptor antagonists, SR140333 and SR48968 in different rat and guinea-pig intestinal segments.
Topics: Animals; Atropine; Benzamides; Duodenum; Esophagus; Gastrointestinal Motility; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Neurokinin A; Piperidines; Quinuclidines; Rats; Receptors, Tachykinin; Substance P | 1995 |
Tachykinin NK3 receptor mediates NANC hyperpolarization and relaxation via nitric oxide release in the circular muscle of the guinea-pig colon.
Topics: Animals; Apamin; Arginine; Atropine; Colon; Dose-Response Relationship, Drug; Guanethidine; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth; Neurokinin B; Nitric Oxide; Nitroarginine; Oligopeptides; Peptide Fragments; Piperidines; Quinuclidines; Receptors, Neurokinin-3; Stereoisomerism; Substance P; Tetrodotoxin | 1994 |
Evidence for a capsaicin-sensitive, tachykinin-mediated, component in the NANC contraction of the rat urinary bladder to nerve stimulation.
Topics: Adenosine Triphosphate; Animals; Atropine; Capsaicin; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Piperidines; Quinuclidines; Rats; Rats, Wistar; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Tachykinins; Urinary Bladder | 1994 |
Characterization of the apamin- and L-nitroarginine-resistant NANC inhibitory transmission to the circular muscle of guinea-pig colon.
Topics: Adrenergic Agents; Animals; Apamin; Atropine; Autonomic Nervous System; Colon; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Guanethidine; Guinea Pigs; Humans; Indoles; Male; Muscarinic Antagonists; Muscle Relaxation; Muscle, Smooth; Nitroarginine; Piperidines; Protease Inhibitors; Quinuclidines; Thiorphan; Vasoactive Intestinal Peptide | 1996 |
Sequential activation of the triple excitatory transmission to the circular muscle of guinea-pig colon.
Topics: 4-Aminopyridine; Animals; Atropine; Colon; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Muscle Contraction; Muscle, Smooth; Neurokinin-1 Receptor Antagonists; Physalaemin; Piperidines; Quinuclidines; Receptors, Neurokinin-2; Stereoisomerism; Synaptic Transmission; Time Factors | 1997 |
The role of tachykinin NK1 and NK2 receptors in atropine-resistant colonic propulsion in anaesthetized guinea-pigs.
Topics: Anesthesia; Animals; Apamin; Atropine; Benzamides; Colon; Guinea Pigs; Hexamethonium; Male; Models, Biological; Muscle Contraction; Neurokinin-1 Receptor Antagonists; Peptides, Cyclic; Peristalsis; Piperidines; Quinuclidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2 | 1998 |
Tachykinin NK1 and NK2 receptor-mediated control of peristaltic propulsion in the guinea-pig small intestine in vitro.
Topics: Animals; Atropine; Benzamides; Female; Guinea Pigs; Hexamethonium; In Vitro Techniques; Intestine, Small; Male; Neurokinin-1 Receptor Antagonists; Peristalsis; Piperidines; Quinuclidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2 | 1998 |
Defaecation, intestinal fluid accumulation and motility in rodents: implications of cannabinoid CB1 receptors.
Topics: Animals; Atropine; Benzamides; Benzoxazines; Body Fluids; Cannabinoids; Defecation; Dose-Response Relationship, Drug; Gastrointestinal Motility; Hexamethonium Compounds; Intestines; Male; Mice; Morpholines; Muscarinic Agonists; Naphthalenes; Neurokinin-1 Receptor Antagonists; Piperidines; Pyrazoles; Quinuclidines; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Drug; Receptors, Muscarinic; Receptors, Neurokinin-2; Rimonabant | 1999 |
Effect of SR-140333, a neurokinin-1 receptor antagonist, on airway reactivity to methacholine in sedated rats.
Topics: Albuterol; Animals; Atropine; Female; In Vitro Techniques; Male; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Neurokinin-1 Receptor Antagonists; Piperidines; Quinuclidines; Rats; Rats, Sprague-Dawley; Respiration; Trachea | 1997 |
An immunohistochemical and pharmacological study of tachykinins in the rat and guinea-pig prostate glands.
Topics: Animals; Atropine; Benzamides; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; Immunohistochemistry; In Vitro Techniques; Male; Muscle Contraction; Neurokinin A; Peptide Fragments; Piperidines; Prostate; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-2; Substance P; Tachykinins | 1999 |
Facilitation of cholinergic transmission by substance P methyl ester in the mouse hippocampal slice preparation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; Action Potentials; Animals; Atropine; Bicuculline; Carbachol; Cholinergic Agonists; Drug Synergism; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; GABA Antagonists; Hippocampus; Male; Membrane Potentials; Mice; Patch-Clamp Techniques; Piperidines; Pyramidal Cells; Quinuclidines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Substance P; Tetrodotoxin; Valine | 2000 |
Evidence for nonvesicular nitric oxide release evoked by nerve activation.
Topics: Acetylcholine; Animals; Atropine; Botulinum Toxins; Botulinum Toxins, Type A; Choline; Electric Stimulation; Enzyme Inhibitors; Exocytosis; Guinea Pigs; Intestines; Membrane Proteins; Muscle, Smooth; Myenteric Plexus; Nerve Tissue Proteins; Neural Inhibition; Nitric Oxide; Nitroarginine; Parasympatholytics; Piperidines; Quinuclidines; R-SNARE Proteins; Synaptic Transmission; Tetrodotoxin; Tritium | 2000 |
Role of tachykininergic and cholinergic pathways in modulating canine gastric tone and compliance in vivo.
Topics: Animals; Atropine; Autonomic Pathways; Benzamides; Compliance; Dogs; Female; Muscarinic Antagonists; Muscle Tonus; Muscle, Smooth; Parasympathetic Nervous System; Piperidines; Pressure; Quinuclidines; Receptors, Tachykinin; Stomach; Tachykinins | 2002 |
Modulatory role of tachykinin NK1 receptor in cholinergic contraction of mouse trachea.
Topics: Animals; Atropine; Chromatography, High Pressure Liquid; Electric Stimulation; Mice; Mice, Knockout; Muscle Contraction; Parasympathetic Nervous System; Piperidines; Quinuclidines; Receptors, Neurokinin-1; Stereoisomerism; Substance P; Synaptic Transmission; Tetrodotoxin; Trachea | 2003 |
Peristalsis regulation by tachykinin NK1 receptors in the rabbit isolated distal colon.
Topics: Alanine; Animals; Atropine; Colon; Drug Interactions; Enzyme Inhibitors; Indoles; Kinetics; Male; Neurokinin-1 Receptor Antagonists; Nitric Oxide Synthase; Nitroarginine; Peptide Fragments; Peristalsis; Piperidines; Pyrrolidonecarboxylic Acid; Quinuclidines; Rabbits; Receptors, Neurokinin-1; Substance P | 2003 |
Bradykinin B2 receptors mediate contraction in the normal and inflamed human gallbladder in vitro.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antipsychotic Agents; Atropine; Benzamides; Bradykinin; Bradykinin Receptor Antagonists; Cyclooxygenase Inhibitors; Female; Gallbladder; Gallbladder Emptying; Gene Expression; Humans; Immunohistochemistry; In Vitro Techniques; Indomethacin; Male; Middle Aged; Muscarinic Antagonists; Piperidines; Quinuclidines; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Receptors, Bradykinin; Reverse Transcriptase Polymerase Chain Reaction; Tritium | 2003 |
Evidence for the presence of functional protease activated receptor 4 (PAR4) in the rat colon.
Topics: Animals; Atropine; Benzamides; Capsaicin; Colitis; Colon; Dose-Response Relationship, Drug; Gastrointestinal Motility; Immunohistochemistry; Male; Muscle Contraction; Muscle, Smooth; Neurokinin-1 Receptor Antagonists; Oligopeptides; Piperidines; Quinuclidines; Rats; Rats, Wistar; Receptors, Neurokinin-2; Receptors, Thrombin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrodotoxin | 2004 |
Cardiovascular responses to rat/mouse hemokinin-1, a mammalian tachykinin peptide: systemic study in anesthetized rats.
Topics: Anesthesia; Animals; Atropine; Benzamides; Blood Pressure; Male; Mice; Muscarinic Antagonists; Neurokinin-1 Receptor Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Piperidines; Protein Precursors; Quinuclidines; Rats; Receptors, Neurokinin-2; Substance P; Tachykinins; Vagotomy; Vagus Nerve | 2007 |
Pharmacological analysis of components of the change in transmural potential difference evoked by distension of rat proximal small intestine in vivo.
Topics: Anesthetics, Local; Animals; Atropine; Chlorides; Colon; Duodenum; Enzyme Inhibitors; Ganglionic Blockers; Granisetron; Hexamethonium; Hormone Antagonists; Injections, Intravenous; Intestinal Secretions; Lidocaine; Male; Mechanotransduction, Cellular; Membrane Potentials; Mice; Mice, Inbred C57BL; Muscarinic Antagonists; Neurokinin-1 Receptor Antagonists; Nitric Oxide Synthase; Nitroarginine; Peripheral Nervous System Agents; Piperidines; Pressure; Quinolines; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Neurokinin-3; Receptors, Serotonin, 5-HT3; Receptors, Vasoactive Intestinal Peptide; Serotonin 5-HT3 Receptor Antagonists; Serotonin Antagonists; Tetrodotoxin; Time Factors; Vasoactive Intestinal Peptide | 2008 |
Cardiovascular responses to intravenous administration of human hemokinin-1 and its truncated form hemokinin-1(4-11) in anesthetized rats.
Topics: Anesthesia; Animals; Atropine; Benzamides; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Humans; Male; NG-Nitroarginine Methyl Ester; Peptide Fragments; Phentolamine; Piperidines; Propranolol; Quinolines; Quinuclidines; Rats; Rats, Wistar; Tachykinins | 2008 |
Guinea pig ileum motility stimulation elicited by N-formyl-Met-Leu-Phe (fMLF) involves neurotransmitters and prostanoids.
Topics: Animals; Atropine; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Gastrointestinal Motility; Gastrointestinal Transit; Guinea Pigs; Ileum; Lower Gastrointestinal Tract; Male; Mice; Mice, Inbred Strains; Muscle Contraction; Muscle, Smooth; N-Formylmethionine Leucyl-Phenylalanine; Neurokinin-1 Receptor Antagonists; Neurotransmitter Agents; Oligopeptides; Piperidines; Piroxicam; Prostaglandins; Quinuclidines; Tetrodotoxin; Thiophenes; Upper Gastrointestinal Tract | 2011 |