sq 28603 has been researched along with cyclic gmp in 12 studies
| Studies (sq 28603) | Trials (sq 28603) | Recent Studies (post-2010) (sq 28603) | Studies (cyclic gmp) | Trials (cyclic gmp) | Recent Studies (post-2010) (cyclic gmp) |
|---|---|---|---|---|---|
| 35 | 0 | 0 | 22,346 | 333 | 4,062 |
| Protein | Taxonomy | sq 28603 (IC50) | cyclic gmp (IC50) |
|---|---|---|---|
| Phosphodiesterase | Bos taurus (cattle) | 0.1 | |
| cGMP-inhibited 3',5'-cyclic phosphodiesterase B | Homo sapiens (human) | 2.4 | |
| cGMP-inhibited 3',5'-cyclic phosphodiesterase A | Homo sapiens (human) | 2.4 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 12 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cernacek, P; Farber, D; Legault, L; Levy, M; Maher, E | 1 |
| Burnett, JC; Margulies, KB; McKinley, LJ; Perrella, MA | 1 |
| Abboa-Offei, B; Asaad, MM; Rogers, WL; Seymour, AA | 1 |
| Asaad, MM; Fennell, SA; Kratunis, VJ; Little, DK; Norman, JA; Rogers, WL; Seymour, AA | 1 |
| Asaad, MM; Dorso, CR; Moreland, SM | 1 |
| Abboa-Offei, BE; Asaad, MM; Mathers, PD; Rogers, WL; Seymour, AA; Smith, PL | 1 |
| Asaad, M; Rogers, WL; Seymour, AA; Sheldon, JH; Smith, PL | 1 |
| Asaad, MM; Cheung, HS; Fennell, SA; Lanoce, VM; Rogers, WL; Seymour, AA | 1 |
| Asaad, MM; Fennell, SA; Langenbacher, KM; Lanoce, VM; Rogers, WL; Seymour, AA | 1 |
| Dietz, R; Höhnel, K; Luft, FC; Scheuermann, M; Willenbrock, R | 1 |
| Abboa-Offei, BE; Asaad, MM; Mathers, PD; Seymour, AA; Weber, H | 1 |
| Dietz, R; Scheuermann, M; Willenbrock, R | 1 |
1 review(s) available for sq 28603 and cyclic gmp
| Article | Year |
|---|---|
Potentiation of natriuretic peptides by neutral endopeptidase inhibitors.
Topics: Alanine; Animals; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Heart Failure; Hemodynamics; Hypertension; Neprilysin | 1995 |
11 other study(ies) available for sq 28603 and cyclic gmp
| Article | Year |
|---|---|
Renal tubular responsiveness to atrial natriuretic peptide in sodium-retaining chronic caval dogs. A possible role for kinins and luminal actions of the peptide.
Topics: Alanine; Animals; Ascites; Atrial Natriuretic Factor; Chronic Disease; Cyclic GMP; Dogs; Female; Kidney Tubules; Kinins; Male; Neprilysin; Protease Inhibitors; Receptors, Bradykinin; Receptors, Neurotransmitter; Sodium | 1992 |
Angiotensin inhibition potentiates the renal responses to neutral endopeptidase inhibition in dogs with congestive heart failure.
Topics: Alanine; Angiotensin II; Animals; Atrial Natriuretic Factor; Cyclic GMP; Dogs; Heart Failure; Hemodynamics; Kidney; Male; Neprilysin; Sodium | 1991 |
Evaluation of SQ 28,603, an inhibitor of neutral endopeptidase, in conscious monkeys.
Topics: Alanine; Animals; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Diuresis; Diuretics; Female; Hemodynamics; Kidney; Macaca fascicularis; Natriuresis; Neprilysin; Peptide Fragments; Sodium | 1991 |
Antihypertensive and renal activity of SQ 28,603, an inhibitor of neutral endopeptidase.
Topics: Alanine; Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Cyclic GMP; Desoxycorticosterone; Diuresis; Hypertension; Infusions, Intravenous; Injections, Intravenous; Kidney; Male; Natriuresis; Neprilysin; Protease Inhibitors; Rats; Rats, Inbred Strains; Sodium Chloride | 1991 |
Effects of neutral endopeptidase inhibition on the clearance of exogenously administered endothelin in Sprague-Dawley rats.
Topics: Alanine; Animals; Atrial Natriuretic Factor; Cyclic GMP; Endothelins; Humans; Metabolic Clearance Rate; Neprilysin; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley | 1993 |
Potentiation of the renal responses to bradykinin by inhibition of neutral endopeptidase 3.4.24.11 and angiotensin-converting enzyme in anesthetized dogs.
Topics: Alanine; Anesthesia; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Captopril; Cyclic GMP; Dogs; Drug Synergism; Female; Kidney; Male; Natriuresis; Neprilysin; Renal Circulation; Vascular Resistance; Vasodilation | 1994 |
Inhibition of neutral endopeptidase 3.4.24.11 in conscious dogs with pacing induced heart failure.
Topics: Alanine; Animals; Atrial Natriuretic Factor; Cardiac Pacing, Artificial; Cyclic GMP; Dogs; Dose-Response Relationship, Drug; Female; Heart Failure; Hemodynamics; Kidney; Male; Natriuresis; Neprilysin; Protease Inhibitors; Urine | 1993 |
Systemic hemodynamics, renal function and hormonal levels during inhibition of neutral endopeptidase 3.4.24.11 and angiotensin-converting enzyme in conscious dogs with pacing-induced heart failure.
Topics: Alanine; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Natriuretic Factor; Captopril; Cardiac Pacing, Artificial; Cyclic GMP; Dogs; Female; Heart Failure; Hemodynamics; Kidney; Male; Neprilysin; Renin | 1993 |
Acute and chronic neutral endopeptidase inhibition in rats with aortocaval shunt.
Topics: Alanine; Angiotensin II; Animals; Aorta, Abdominal; Arteriovenous Shunt, Surgical; Atrial Natriuretic Factor; Cyclic GMP; Diuresis; Enzyme Inhibitors; Heart Failure; Hemodynamics; Male; Natriuresis; Neprilysin; Rats; Rats, Wistar; Renin; Vena Cava, Inferior | 1996 |
Renal and depressor activity of C-natriuretic peptide in conscious monkeys: effects of enzyme inhibitors.
Topics: Alanine; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Cyclic GMP; Enzyme Inhibitors; Female; Kidney; Macaca fascicularis; Natriuretic Peptide, C-Type; Neprilysin; Proteins; Sodium | 1996 |
Acute and chronic neutral endopeptidase inhibition and the natriuretic response to acute volume expansion.
Topics: Alanine; Animals; Atrial Natriuretic Factor; Blood Pressure; Body Weight; Cyclic GMP; Diuresis; Enzyme Inhibitors; Heart Rate; Hemodynamics; Kidney; Male; Natriuresis; Neprilysin; Rats; Rats, Wistar | 1998 |