Compounds > sq 20006
Page last updated: 2024-09-04

sq 20006 and wortmannin

sq 20006 has been researched along with wortmannin in 3 studies

Compound Research Comparison

Studies
(sq 20006)		Trials
(sq 20006)		Recent Studies (post-2010)
(sq 20006)		Studies
(wortmannin)		Trials
(wortmannin)		Recent Studies (post-2010) (wortmannin)
8004,0662726

Protein Interaction Comparison

ProteinTaxonomysq 20006 (IC50)wortmannin (IC50)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformHomo sapiens (human)0.0465
Myosin light chain kinase, smooth muscleGallus gallus (chicken)0.26
Metabotropic glutamate receptor 1Rattus norvegicus (Norway rat)0.0085
Phosphatidylinositol 3-kinase regulatory subunit alphaHomo sapiens (human)0.2368
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformHomo sapiens (human)0.1309
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformHomo sapiens (human)0.0493
Serine/threonine-protein kinase mTORHomo sapiens (human)0.04
Phosphatidylinositol 4-kinase alphaHomo sapiens (human)0.28
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Homo sapiens (human)0.0492
Serine/threonine-protein kinase PLK1Homo sapiens (human)0.4433
Myosin light chain kinase, smooth muscleHomo sapiens (human)2.3567
Phosphoinositide 3-kinase regulatory subunit 5Homo sapiens (human)0.019
Serine/threonine-protein kinase PLK3Homo sapiens (human)0.1057
Phosphatidylinositol 4-kinase betaHomo sapiens (human)0.44

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dennis, PB; Han, JW; Pearson, RB; Thomas, G1
Gingras, AC; Ming, XF; Sonenberg, N; Thomas, G; von Manteuffel, SR1
Dennis, PB; Kozma, SC; Pullen, N; Thomas, G1

Other Studies

3 other study(ies) available for sq 20006 and wortmannin

ArticleYear
Rapamycin, wortmannin, and the methylxanthine SQ20006 inactivate p70s6k by inducing dephosphorylation of the same subset of sites.
    The Journal of biological chemistry, 1995, Sep-08, Volume: 270, Issue:36

    Topics: 3T3 Cells; Amino Acid Sequence; Androstadienes; Animals; Base Sequence; Blood; Immunosuppressive Agents; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Nicotinic Acids; Oligodeoxyribonucleotides; Phosphorylation; Polyenes; Protein Serine-Threonine Kinases; Ribosomal Protein S6 Kinases; Sirolimus; Substrate Specificity; Tacrolimus; Tetradecanoylphorbol Acetate; Wortmannin

1995
4E-BP1 phosphorylation is mediated by the FRAP-p70s6k pathway and is independent of mitogen-activated protein kinase.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, Apr-30, Volume: 93, Issue:9

    Topics: 3T3 Cells; Adaptor Proteins, Signal Transducing; Androstadienes; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Carrier Proteins; Cell Cycle Proteins; Cell Line; Enzyme Activation; Enzyme Inhibitors; Eukaryotic Initiation Factors; Humans; Immunosuppressive Agents; Insulin; Kidney; Kinetics; Mice; Nicotinic Acids; Phosphodiesterase Inhibitors; Phosphoproteins; Phosphorylation; Polyenes; Protein Serine-Threonine Kinases; Ribosomal Protein S6 Kinases; Signal Transduction; Sirolimus; Tetradecanoylphorbol Acetate; Wortmannin

1996
The principal rapamycin-sensitive p70(s6k) phosphorylation sites, T-229 and T-389, are differentially regulated by rapamycin-insensitive kinase kinases.
    Molecular and cellular biology, 1996, Volume: 16, Issue:11

    Topics: Amino Acid Sequence; Androstadienes; Cell Line; Humans; Immunosuppressive Agents; Kidney; Mitogen-Activated Protein Kinase Kinases; Molecular Sequence Data; Mutagenesis, Site-Directed; Nicotinic Acids; Peptide Mapping; Phosphates; Phosphodiesterase Inhibitors; Phosphopeptides; Phosphorylation; Polyenes; Protein Kinases; Protein Serine-Threonine Kinases; Recombinant Proteins; Ribosomal Protein S6 Kinases; Sequence Deletion; Sirolimus; Transfection; Tyrosine; Wortmannin

1996