Compounds > sq 20006
Page last updated: 2024-09-04

sq 20006 and 1-methyl-3-isobutylxanthine

sq 20006 has been researched along with 1-methyl-3-isobutylxanthine in 3 studies

Compound Research Comparison

Studies
(sq 20006)		Trials
(sq 20006)		Recent Studies (post-2010)
(sq 20006)		Studies
(1-methyl-3-isobutylxanthine)		Trials
(1-methyl-3-isobutylxanthine)		Recent Studies (post-2010) (1-methyl-3-isobutylxanthine)
8005,1485279

Protein Interaction Comparison

ProteinTaxonomysq 20006 (IC50)1-methyl-3-isobutylxanthine (IC50)
Chain A, High-affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7AHomo sapiens (human)8.1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)31
Chain A, Phosphodiesterase 9AHomo sapiens (human)500
Chain A, Class I phosphodiesterase PDEB1Leishmania major580
Chain A, High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8AHomo sapiens (human)698
Chain A, cGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)40
Chain A, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9AHomo sapiens (human)117.2
Chain A, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9AHomo sapiens (human)117.2
Phosphodiesterase Bos taurus (cattle)9.9
cGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)4
cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)3.1667
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A Bos taurus (cattle)9.9
Adenosine receptor A1Rattus norvegicus (Norway rat)7
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1AHomo sapiens (human)3.4
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1BBos taurus (cattle)9.9
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1BHomo sapiens (human)3.4
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1BRattus norvegicus (Norway rat)0.1
cGMP-inhibited 3',5'-cyclic phosphodiesterase BHomo sapiens (human)0.242
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1CHomo sapiens (human)3.4
cGMP-inhibited 3',5'-cyclic phosphodiesterase AHomo sapiens (human)7
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1CRattus norvegicus (Norway rat)0.1
Phosphodiesterase Rattus norvegicus (Norway rat)0.1

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alberts, P; Ogren, VR; Sellström, AI1
Fredholm, BB; Johansson, B; Svenningsson, P1
Fabbro, D; Ferrari, S; Frost, V; Mercep, L; Meyer, T; Morley, SJ1

Other Studies

3 other study(ies) available for sq 20006 and 1-methyl-3-isobutylxanthine

ArticleYear
Role of adenosine 3',5'-cyclic monophosphate in adrenoceptor-mediated control of 3H-noradrenaline secretion in guinea-pig ileum myenteric nerve terminals.
    Naunyn-Schmiedeberg's archives of pharmacology, 1985, Volume: 330, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Colforsin; Cyclic AMP; Cyclic GMP; Guinea Pigs; Ileum; In Vitro Techniques; Isoproterenol; Male; Myenteric Plexus; Nerve Endings; Nicotinic Acids; Norepinephrine; Phosphodiesterase Inhibitors; Propranolol; Receptors, Adrenergic; Yohimbine

1985
Effect of different xanthines and phosphodiesterase inhibitors on c-fos expression in rat striatum.
    Acta physiologica Scandinavica, 1995, Volume: 154, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Caffeine; Dose-Response Relationship, Drug; Drug Administration Schedule; In Situ Hybridization; Male; Neostriatum; Nicotinic Acids; Phosphodiesterase Inhibitors; Proto-Oncogene Proteins c-fos; Purinones; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Rolipram; Xanthines

1995
The phosphodiesterase inhibitor SQ 20006 selectively blocks mitogen activation of p70S6k and transition to S phase of the cell division cycle without affecting the steady state phosphorylation of eIF-4E.
    The Journal of biological chemistry, 1995, Nov-03, Volume: 270, Issue:44

    Topics: 1-Methyl-3-isobutylxanthine; 3T3 Cells; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle; Cell Division; Cell Line; Cyclic AMP; Emetine; Enzyme Activation; Eukaryotic Initiation Factor-4E; Humans; Hydroxyurea; Immunosuppressive Agents; Kinetics; Mice; Mitogen-Activated Protein Kinase 1; Mitogens; Nicotinic Acids; Peptide Initiation Factors; Phosphodiesterase Inhibitors; Phosphorylation; Polyenes; Polyribosomes; Protein Biosynthesis; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Reticulocytes; Ribosomal Protein S6 Kinases; S Phase; Sirolimus

1995