sq-11725 has been researched along with prazosin in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (30.77) | 18.7374 |
| 1990's | 7 (26.92) | 18.2507 |
| 2000's | 7 (26.92) | 29.6817 |
| 2010's | 4 (15.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Akhmedova, ZG; Gumbatov, NB; Karaev, ME; Kasumova, FZ; Mamedova, RN; Mustafaev, II | 1 |
| Filatova, NP; Metelitsa, VI | 3 |
| Kopaciewicz, LJ; Kopia, GA; Ruffolo, RR | 1 |
| Kawada, M; Satoh, K; Taira, N | 1 |
| Katus, H; Mall, G; Mehls, O; Rambausek, M; Ritz, E | 1 |
| Cox, DA; Leader, JP; Milson, JA; Singleton, W | 1 |
| Weinshilboum, RM | 1 |
| Kraut, J; Okun, R | 1 |
| Piotrovskii, VK | 1 |
| Belolipetskaya, VG; El'man, AR; Metelitsa, VI; Piotrovskii, VK | 1 |
| Ageel, AM; Alhaider, AA; Ginawi, OT | 1 |
| Hori, T; Katafuchi, T; Take, S | 1 |
| Harmsen, E; Leenen, FH; Song, D | 1 |
| Eschenhagen, T; Grimm, M; Haas, P; Pantel, K; Rau, T; Weyand, M; Willipinski-Stapelfeldt, B; Zimmermann, WH | 1 |
5 trial(s) available for sq-11725 and prazosin
| Article | Year |
|---|---|
[The results of the comparative study of nadolol, propranolol, prazosin and hydrochlorothiazide in patients with arterial hypertension in a 12-month stepped-plan treatment (cooperative research). The Working Group of the Cooperative Program to Study New P
Topics: Adult; Blood Pressure; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nadolol; Prazosin; Propranolol; Remission Induction; Time Factors; USSR | 1991 |
The results of the comparative study of nadolol, propranolol, prazosin and hydrochlorothiazide in patients with arterial hypertension in a 12-month stepped-plan treatment (cooperative research). The Working Group of the Cooperative Program to Study New Pr
Topics: Adult; Blood Pressure; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nadolol; Patient Dropouts; Prazosin; Propranolol; Remission Induction; Time Factors; USSR | 1991 |
[Role of a beta adrenergic blocking agent nadolol (corgard) in prevention of arterial hypertension: a 6-month treatment (cooperative study)].
Topics: Adult; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Multicenter Studies as Topic; Nadolol; Prazosin; Propranolol; Time Factors | 1990 |
The antihypertensive effects of doxazosin: a clinical overview.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Cholesterol; Cholesterol, HDL; Clinical Trials as Topic; Double-Blind Method; Doxazosin; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Kinetics; Male; Metoprolol; Middle Aged; Nadolol; Prazosin; Propanolamines; Random Allocation; Risk; Triglycerides | 1986 |
A comparison of prazosin versus nadolol in combination with a diuretic.
Topics: Adrenergic beta-Antagonists; Blood Pressure; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Hypertension; Male; Middle Aged; Nadolol; Polythiazide; Potassium; Prazosin; Propanolamines; Quinazolines; Time Factors | 1984 |
21 other study(ies) available for sq-11725 and prazosin
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
[Effect of long-term treatment with prazosin and its combination with nadolol on the levels of blood hormones of the hypophyseal- gonadal system in patients with hypertension].
Topics: Adult; Drug Therapy, Combination; Estradiol; Humans; Hyperprolactinemia; Hypertension; Male; Middle Aged; Nadolol; Pituitary Hormones, Anterior; Prazosin; Testosterone; Time Factors | 1992 |
Alpha adrenoceptor regulation of coronary artery blood flow in normal and stenotic canine coronary arteries.
Topics: Adrenergic alpha-Antagonists; Animals; Arterial Occlusive Diseases; Blood Pressure; Coronary Circulation; Coronary Vessels; Dioxanes; Dogs; Electric Stimulation; Electrocardiography; Electrophysiology; Female; Heart Conduction System; Heart Rate; Idazoxan; Male; Nadolol; Prazosin; Receptors, Adrenergic, alpha; Regional Blood Flow; Sympathetic Nervous System | 1986 |
Cardiohemodynamic effects of nipradilol (K-351) in the dog: comparison with propranolol, nadolol and prazosin.
Topics: Adrenergic beta-Antagonists; Animals; Dogs; Dose-Response Relationship, Drug; Female; Hemodynamics; Male; Nadolol; Prazosin; Propanolamines; Propranolol | 1986 |
Myocardial hypertrophy in rats with renal insufficiency.
Topics: Adenosine Triphosphatases; Animals; Blood Pressure; Blood Transfusion; Calcium; Cardiomegaly; Hydralazine; Isoenzymes; Kidney Diseases; Male; Metoprolol; Microscopy, Electron; Myocardium; Myosins; Nadolol; Nephrectomy; Organ Size; Parathyroid Glands; Prazosin; Propanolamines; Rats; Rats, Inbred Strains; Trifluoperazine | 1985 |
Antihypertensive drugs that alter adrenergic function.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Catecholamines; Central Nervous System; Clonidine; Guanethidine; Humans; Methyldopa; Metoprolol; Nadolol; Prazosin; Propanolamines; Propranolol; Receptors, Adrenergic; Reserpine; Sympathetic Nervous System | 1980 |
On the usefulness of ultrafiltration in drug-protein binding studies.
Topics: Nadolol; Nifedipine; Pharmaceutical Preparations; Prazosin; Propanolamines; Protein Binding; Ultrafiltration; Verapamil | 1984 |
Ion-exchange high-performance liquid chromatography in drug assay in biological fluids. III. Propranolol, nadolol and prazosin.
Topics: Chromatography, High Pressure Liquid; Humans; Nadolol; Prazosin; Propanolamines; Propranolol; Quinazolines; Saliva | 1983 |
The quipazine- and TFMPP-increased conditioned avoidance response in rats: role of 5HT1C/5-HT2 receptors.
Topics: Animals; Avoidance Learning; Conditioning, Operant; Ketanserin; Male; Mianserin; Nadolol; Pindolol; Piperazines; Prazosin; Quipazine; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Reference Values; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone; Tropanes | 1993 |
Roles of sympathetic nervous system in the suppression of cytotoxicity of splenic natural killer cells in the rat.
Topics: Animals; Blood Pressure; Cell Survival; Denervation; Electric Stimulation; Injections, Intraventricular; Interferon Type I; Killer Cells, Natural; Male; Nadolol; Naloxone; Neurons, Efferent; Prazosin; Rats; Rats, Wistar; Recombinant Proteins; Spleen; Sympathetic Nervous System; Tumor Cells, Cultured | 1993 |
alpha- and beta-adrenoceptor blockade fail to prevent high sodium diet-induced left ventricular hypertrophy.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Body Weight; Drinking; Ganglionic Blockers; Hypertrophy, Left Ventricular; Male; Myocardium; Nadolol; Prazosin; Rats; Rats, Inbred WKY; Sodium Chloride, Dietary; Weight Gain | 1997 |
Key role of myosin light chain (MLC) kinase-mediated MLC2a phosphorylation in the alpha 1-adrenergic positive inotropic effect in human atrium.
Topics: Adolescent; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Analysis of Variance; Androstadienes; Azepines; Cardiac Myosins; Child; Child, Preschool; Electrophoresis, Gel, Two-Dimensional; Enzyme Inhibitors; Female; Heart Atria; Humans; Immunohistochemistry; In Vitro Techniques; Male; Microscopy, Confocal; Middle Aged; Myocardial Contraction; Myocardium; Myosin Light Chains; Myosin-Light-Chain Kinase; Nadolol; Naphthalenes; Phenylephrine; Phosphorylation; Prazosin; Protein Kinase Inhibitors; Stimulation, Chemical; Wortmannin | 2005 |