splenotritin has been researched along with suramin in 1 studies
*Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties. [MeSH]
*Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties. [MeSH]
| Studies (splenotritin) | Trials (splenotritin) | Recent Studies (post-2010) (splenotritin) | Studies (suramin) | Trials (suramin) | Recent Studies (post-2010) (suramin) |
|---|---|---|---|---|---|
| 7 | 0 | 1 | 3,023 | 92 | 431 |
| Protein | Taxonomy | splenotritin (IC50) | suramin (IC50) |
|---|---|---|---|
| ATP-dependent 6-phosphofructokinase | Trypanosoma brucei brucei | 3 | |
| Tyrosine-protein phosphatase non-receptor type 1 | Homo sapiens (human) | 9.76 | |
| P2X purinoceptor 2 | Rattus norvegicus (Norway rat) | 4 | |
| DNA-dependent protein kinase catalytic subunit | Homo sapiens (human) | 1.7 | |
| DNA primase | Mycobacterium tuberculosis CDC1551 | 8.2 | |
| RmtA | Aspergillus nidulans | 5.9 | |
| Reverse transcriptase/RNaseH | Human immunodeficiency virus 1 | 9.4 | |
| NAD-dependent protein deacetylase sirtuin-2 | Homo sapiens (human) | 1.15 | |
| NAD-dependent protein deacetylase sirtuin-1 | Homo sapiens (human) | 1.5667 | |
| Protein arginine N-methyltransferase 1 | Homo sapiens (human) | 5.33 | |
| NAD-dependent protein deacylase sirtuin-5, mitochondrial | Homo sapiens (human) | 2.5 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dénes, L; Hajós, G; Lapis, K; Sipka, S; Szegedi, G; Szende, B; Szporny, L | 1 |
1 other study(ies) available for splenotritin and suramin
| Article | Year |
|---|---|
The effect of thymopoietin 32-34 (TP3) on suramin-induced inhibition on delayed type hypersensitivity in guinea pigs.
Topics: Animals; Guinea Pigs; Hypersensitivity, Delayed; Immunity, Cellular; Oligopeptides; Peptide Fragments; Suramin; Thymopentin; Thymopoietins; Thymus Hormones | 1987 |