spironolactone has been researched along with zk 91587 in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (25.00) | 18.7374 |
| 1990's | 12 (60.00) | 18.2507 |
| 2000's | 3 (15.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| De Nicola, AF; Grillo, C; McEwen, BS; Piroli, G; Vallee, SM | 1 |
| De Nicola, AF; Grillo, C; McEwen, BS; Vallee, S | 1 |
| De Nicola, AF; Ferrini, M; Magariños, AM | 1 |
| Bittler, D; Laurent, H; Losert, W; Nickisch, K; Nishino, Y; Schillinger, E; Wiechert, R | 1 |
| Agarwal, MK; Kalimi, M | 3 |
| de Kloet, ER; Sutanto, W | 1 |
| el Etreby, MF; Nishino, Y; Schröder, H | 1 |
| Cosen-Binker, L; de Kloet, ER; De Nicola, AF; Gonzalez, S; Grillo, CA; McEwen, BS; Vallee, SM | 1 |
| Baulieu, EE; Binart, N; Delahaye, F; Lombès, M; Rafestin-Oblin, ME | 1 |
| Baker, ME; Rodbard, D; Rondinone, CM | 1 |
| Hastings, NB; McEwen, BS | 1 |
| Burton, G; Galigniana, MD; Lantos, CP; Monteserín, MC; Veleiro, AS; Vicent, GP | 1 |
| Fejes-Tóth, G; Náray-Fejes-Tóth, A; Pearce, D | 1 |
| Asano, Y; Ebata, S; Kawakami, K; Muto, S; Nemoto, J | 1 |
| Grafte-Faure, S; Leveque, C; Norris, V; Soria, C; Vannier, JP; Vasse, M | 1 |
| Agarwal, MK; Golestaneh, N; Mirshahi, M; Valamanesh, F | 1 |
| Agarwal, MK; Golestaneh, N; Klein, C; Mirshahi, M; Suarez, G; Valamanesh, F | 1 |
| Bussolino, D; Calfa, G; Molina, VA | 1 |
20 other study(ies) available for spironolactone and zk 91587
| Article | Year |
|---|---|
Transformation and nuclear translocation of brain type L corticosteroid receptors complexed with the mineralocorticoid antagonist ZK 91587, aldosterone or dexamethasone.
Topics: Aldosterone; Amygdala; Animals; Cell Nucleus; Cellulose; Culture Techniques; Dexamethasone; DNA; Hippocampus; Male; Mineralocorticoids; Rats; Rats, Inbred Strains; Receptors, Glucocorticoid; Spironolactone | 1992 |
Properties and distribution of binding sites for the mineralocorticoid receptor antagonist [3H]ZK 91587 in brain.
Topics: Adrenalectomy; Aldosterone; Amygdala; Animals; Binding, Competitive; Brain; Corticosterone; Hippocampus; Male; Mineralocorticoid Receptor Antagonists; Mineralocorticoids; Rats; Rats, Inbred Strains; Receptors, Mineralocorticoid; Receptors, Steroid; Septum Pellucidum; Spironolactone; Tissue Distribution | 1990 |
Oestrogens down-regulate type I but not type II adrenal corticoid receptors in rat anterior pituitary.
Topics: Adrenalectomy; Adrenocorticotropic Hormone; Animals; Castration; Dexamethasone; Down-Regulation; Estradiol; Female; Hippocampus; Male; Mineralocorticoids; Pituitary Gland, Anterior; Pituitary Gland, Posterior; Rats; Rats, Inbred Strains; Receptors, Corticotropin; Receptors, Pituitary Hormone; Sex Factors; Spironolactone | 1990 |
Aldosterone antagonists. 3. Synthesis and activities of steroidal 7 alpha-(alkoxycarbonyl)-15,16-methylene spirolactones.
Topics: Animals; Biological Assay; Chemical Phenomena; Chemistry; Female; Male; Mineralocorticoid Receptor Antagonists; Orchiectomy; Ovulation; Pregnadienes; Pregnancy; Rabbits; Rats; Rats, Inbred Strains; Receptors, Androgen; Receptors, Progesterone; Spironolactone; Structure-Activity Relationship | 1990 |
Analysis of the mineralocorticoid receptor in rat heart with the aid of two new spirolactone derivatives.
Topics: Animals; Chromatography, Ion Exchange; Kinetics; Male; Mineralocorticoids; Myocardium; Rats; Rats, Inbred Strains; Receptors, Mineralocorticoid; Receptors, Steroid; Spironolactone | 1989 |
Paradoxical differences in the receptor binding of two new antimineralocorticoids.
Topics: Adrenalectomy; Aldosterone; Animals; Cytosol; Hot Temperature; Kidney; Kinetics; Male; Mineralocorticoid Receptor Antagonists; Mineralocorticoids; Rats; Rats, Inbred Strains; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Receptors, Steroid; Spironolactone; Thermodynamics | 1988 |
Different mechanisms for the receptor mediated antimineralocorticoid action of two new spirolactone derivatives.
Topics: Animals; Binding, Competitive; Centrifugation, Density Gradient; Cytosol; Hot Temperature; Kidney; Kinetics; Liver; Lung; Male; Mineralocorticoid Receptor Antagonists; Mineralocorticoids; Molybdenum; Rats; Rats, Inbred Strains; Receptors, Mineralocorticoid; Receptors, Steroid; Spironolactone | 1988 |
ZK91587: a novel synthetic antimineralocorticoid displays high affinity for corticosterone (type I) receptors in the rat hippocampus.
Topics: Animals; Binding, Competitive; Corticosterone; Cytosol; Hippocampus; Kinetics; Male; Mineralocorticoids; Rats; Rats, Inbred Strains; Receptors, Glucocorticoid; Receptors, Steroid; Spironolactone | 1988 |
Experimental studies on the endocrine side effects of new aldosterone antagonists.
Topics: Androgen Antagonists; Animals; Chorionic Gonadotropin; Endocrine System Diseases; Luteinizing Hormone; Macaca fascicularis; Male; Mice; Mineralocorticoid Receptor Antagonists; Progesterone; Rabbits; Rats; Rats, Inbred Strains; Sexual Behavior, Animal; Spironolactone; Testosterone | 1988 |
Further studies in deoxycorticosterone acetate treated rats: brain content of mineralocorticoid and glucocorticoid receptors and effect of steroid antagonists on salt intake.
Topics: Amygdala; Animals; Appetite; Brain; Desoxycorticosterone; Hippocampus; Hypothalamus; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Ornithine Decarboxylase; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Sodium Chloride, Dietary; Spironolactone | 1995 |
Differential intracellular localization of human mineralocorticosteroid receptor on binding of agonists and antagonists.
Topics: Aldosterone; Animals; Cell Line; Cloning, Molecular; Humans; Immunohistochemistry; Ligands; Mice; Mice, Inbred BALB C; Mineralocorticoid Receptor Antagonists; Mineralocorticoids; Moths; Nucleopolyhedroviruses; Progesterone; Receptors, Mineralocorticoid; Spironolactone | 1994 |
Aldosterone stimulated differentiation of mouse 3T3-L1 cells into adipocytes.
Topics: 3T3 Cells; Adipose Tissue; Aldosterone; Androstanols; Animals; Binding, Competitive; Cell Differentiation; Glycerolphosphate Dehydrogenase; Hydrocortisone; Mice; Receptors, Glucocorticoid; Spironolactone; Triglycerides | 1993 |
Characterization of adrenal hormone binding sites in the prairie vole.
Topics: Adrenalectomy; Adrenocorticotropic Hormone; Aldosterone; Androstanols; Animals; Arginine Vasopressin; Arvicolinae; Binding Sites; Brain; Cytosol; Dexamethasone; Hypertrophy; Kinetics; Mineralocorticoids; Rats; Receptors, Glucocorticoid; Spironolactone; Thymus Gland | 1997 |
21-Hydroxy-6,19-oxidoprogesterone: a novel synthetic steroid with specific antiglucocorticoid properties in the rat.
Topics: Aldosterone; Androstanols; Animals; Kidney; Male; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone; Structure-Activity Relationship; Thymus Gland; Transcortin; Tritium | 1997 |
Subcellular localization of mineralocorticoid receptors in living cells: effects of receptor agonists and antagonists.
Topics: Aldosterone; Animals; Biological Transport; Cell Compartmentation; Cells, Cultured; Genes, Reporter; Green Fluorescent Proteins; Luminescent Proteins; Mineralocorticoid Receptor Antagonists; Nuclear Matrix; Protein Binding; Receptors, Mineralocorticoid; Recombinant Fusion Proteins; Spironolactone; Transcription, Genetic | 1998 |
Corticosterone and 11-dehydrocorticosterone stimulate Na,K-ATPase gene expression in vascular smooth muscle cells.
Topics: Animals; Aorta; Cells, Cultured; Corticosterone; Dactinomycin; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Male; Mifepristone; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium-Potassium-Exchanging ATPase; Spironolactone | 1998 |
Effects of glucocorticoids and mineralocorticoids on proliferation and maturation of human peripheral blood stem cells.
Topics: Adult; Aldosterone; Cells, Cultured; Colony-Forming Units Assay; Desoxycorticosterone; Erythropoietin; Glucocorticoids; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cells; Humans; Interleukin-3; Mifepristone; Mineralocorticoids; Recombinant Proteins; Spironolactone; Triamcinolone Acetonide | 1999 |
Paradoxical effects of mineralocorticoids on the ion gated sodium channel in embryologically diverse cells.
Topics: Aldosterone; Animals; Cattle; Cell Division; Cells, Cultured; Cornea; Embryo, Mammalian; Epithelial Sodium Channels; Fibroblasts; Humans; Ion Channel Gating; Leukemia, Erythroblastic, Acute; Mineralocorticoid Receptor Antagonists; Mineralocorticoids; Pigment Epithelium of Eye; Receptors, Mineralocorticoid; Sodium Channels; Spironolactone; Tumor Cells, Cultured | 2000 |
Mineralocorticoid receptor-mediated signaling regulates the ion gated sodium channel in vascular endothelial cells and requires an intact cytoskeleton.
Topics: Actins; Aldosterone; Cell Line; Cytochalasin D; Cytoskeleton; Endothelium, Vascular; Epithelial Sodium Channels; Ethanol; Humans; Immunohistochemistry; Microscopy, Confocal; Receptors, Mineralocorticoid; RNA, Messenger; Signal Transduction; Sodium Channels; Spironolactone; Tubulin | 2001 |
Involvement of the lateral septum and the ventral Hippocampus in the emotional sequelae induced by social defeat: role of glucocorticoid receptors.
Topics: Aggression; Analysis of Variance; Anesthetics, Local; Animals; Behavior, Animal; Dominance-Subordination; Emotions; Hippocampus; Hormone Antagonists; Lidocaine; Male; Maze Learning; Mifepristone; Oncogene Proteins v-fos; Rats; Rats, Wistar; Reaction Time; Receptors, Glucocorticoid; Septal Nuclei; Spironolactone; Stress, Psychological | 2007 |