Page last updated: 2024-08-17

spironolactone and trandolapril

spironolactone has been researched along with trandolapril in 15 studies

Research

Studies (15)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	13 (86.67)	29.6817
2010's	2 (13.33)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Bauersachs, J; Christ, M; Ertl, G; Fraccarollo, D; Gretz, N; Wehling, M	1
Saruta, T; Sato, A; Takane, H	1
Bauersachs, J; Christ, M; Ertl, G; Fraccarollo, D; Heck, M; Hildemann, SK; Wehling, M	1
Hayashi, M; Saruta, T; Sato, A	1
Bauersachs, J; Christ, M; Eigenthaler, M; Fraccarollo, D; Hildemann, S; Kobsar, A; Schäfer, A; Walter, U	1
Bauersachs, J; Ertl, G; Fraccarollo, D; Hildemann, SK; Schäfer, A; Tas, P	1
Bauersachs, J; Christ, M; Ertl, G; Fraccarollo, D; Galuppo, P; Hildemann, S	1
Pfeffer, MA; Solomon, SD	1
Cohen-Solal, A; Dietz, R; Eichhorn, E; Erhardt, L; Hobbs, FD; Krum, H; Maggioni, A; McKelvie, RS; McMurray, J; Piña, IL; Soler-Soler, J; Swedberg, K	1
Fujita, T; Goto, A; Kobayashi, N; Matsuoka, H; Onozato, ML; Tojo, A	1
Czupryniak, L; Loba, J; Pawłowski, M; Saryusz-Wolska, M	1

Reviews

1 review(s) available for spironolactone and trandolapril

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

4 trial(s) available for spironolactone and trandolapril

Article	Year
Striking increase of natriuresis by low-dose spironolactone in congestive heart failure only in combination with ACE inhibition: mechanistic evidence to support RALES. Circulation, 2000, Nov-07, Volume: 102, Issue:19 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Heart Failure; Humans; Indoles; Mineralocorticoid Receptor Antagonists; Natriuresis; Rats; Rats, Wistar; Spironolactone	2000
High serum level of procollagen type III amino-terminal peptide contributes to the efficacy of spironolactone and angiotensin-converting enzyme inhibitor therapy on left ventricular hypertrophy in essential hypertensive patients. Hypertension research : official journal of the Japanese Society of Hypertension, 2001, Volume: 24, Issue:2 Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Diuretics; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Indoles; Male; Middle Aged; Peptide Fragments; Procollagen; Spironolactone; Treatment Outcome	2001
Relative long-term effects of spironolactone in conjunction with an angiotensin-converting enzyme inhibitor on left ventricular mass and diastolic function in patients with essential hypertension. Hypertension research : official journal of the Japanese Society of Hypertension, 2002, Volume: 25, Issue:6 Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Flow Velocity; Blood Pressure; Coronary Circulation; Diastole; Drug Therapy, Combination; Echocardiography; Enalapril; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Indoles; Longitudinal Studies; Male; Middle Aged; Peptide Fragments; Procollagen; Spironolactone	2002
Circadian blood pressure variation and antihypertensive medication adjustment in normoalbuminuric type 2 diabetes patients. Kidney & blood pressure research, 2007, Volume: 30, Issue:3 Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Bisoprolol; Blood Pressure; Circadian Rhythm; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Humans; Hypertension, Renal; Indapamide; Indoles; Male; Middle Aged; Nitrendipine; Perindopril; Spironolactone	2007

Other Studies

10 other study(ies) available for spironolactone and trandolapril

Article	Year
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Addition of spironolactone to angiotensin-converting enzyme inhibition in heart failure improves endothelial vasomotor dysfunction: role of vascular superoxide anion formation and endothelial nitric oxide synthase expression. Journal of the American College of Cardiology, 2002, Jan-16, Volume: 39, Issue:2 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Drug Therapy, Combination; Endothelium, Vascular; Heart Failure; Indoles; Male; Mineralocorticoid Receptor Antagonists; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Rats; Rats, Wistar; Spironolactone; Superoxides; Vasodilation; Ventricular Remodeling	2002
Inhibition of platelet activation in congestive heart failure by aldosterone receptor antagonism and ACE inhibition. Thrombosis and haemostasis, 2003, Volume: 89, Issue:6 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Cell Adhesion Molecules; Drug Therapy, Combination; Eplerenone; Fibrinogen; Heart Failure; Indoles; Male; Microfilament Proteins; Mineralocorticoid Receptor Antagonists; Nitric Oxide; P-Selectin; Phosphoproteins; Platelet Activation; Rats; Rats, Wistar; Renin-Angiotensin System; Spironolactone	2003
Addition of the selective aldosterone receptor antagonist eplerenone to ACE inhibition in heart failure: effect on endothelial dysfunction. Cardiovascular research, 2003, Jun-01, Volume: 58, Issue:3 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Blotting, Western; Drug Therapy, Combination; Endothelium, Vascular; Eplerenone; Heart Failure; In Vitro Techniques; Indoles; Male; Mineralocorticoid Receptor Antagonists; Myocardial Infarction; Nitroprusside; Rats; Rats, Wistar; Spironolactone; Vasodilator Agents	2003
Additive improvement of left ventricular remodeling and neurohormonal activation by aldosterone receptor blockade with eplerenone and ACE inhibition in rats with myocardial infarction. Journal of the American College of Cardiology, 2003, Nov-05, Volume: 42, Issue:9 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blotting, Western; Drug Synergism; Drug Therapy, Combination; Endothelium, Vascular; Eplerenone; Hemodynamics; Indoles; Male; Mineralocorticoid Receptor Antagonists; Myocardial Infarction; Nitric Oxide Synthase; Rats; Spironolactone; Ventricular Dysfunction, Left; Ventricular Remodeling	2003
Aldosterone antagonism and myocardial infarction: from animals to man and back. Journal of the American College of Cardiology, 2003, Nov-05, Volume: 42, Issue:9 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Drug Synergism; Drug Therapy, Combination; Eplerenone; Humans; Indoles; Mineralocorticoid Receptor Antagonists; Spironolactone; Ventricular Remodeling	2003
Practical recommendations for the use of ACE inhibitors, beta-blockers, aldosterone antagonists and angiotensin receptor blockers in heart failure: putting guidelines into practice. European journal of heart failure, 2005, Volume: 7, Issue:5 Topics: Adrenergic beta-Antagonists; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Benzopyrans; Biphenyl Compounds; Bisoprolol; Captopril; Carbazoles; Carvedilol; Drug Therapy, Combination; Enalapril; Ethanolamines; Evidence-Based Medicine; Guideline Adherence; Heart Failure; Humans; Indoles; Lisinopril; Metoprolol; Mineralocorticoid Receptor Antagonists; Nebivolol; Practice Guidelines as Topic; Propanolamines; Ramipril; Spironolactone; Stroke Volume; Tetrazoles; Valine; Valsartan	2005
Dual blockade of aldosterone and angiotensin II additively suppresses TGF-beta and NADPH oxidase in the hypertensive kidney. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2007, Volume: 22, Issue:5 Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiac Output, Low; Drug Synergism; Eplerenone; Hypertension; Indoles; Kidney; Male; Mineralocorticoid Receptor Antagonists; NADPH Oxidases; Oxidative Stress; Rats; Rats, Inbred Dahl; Reactive Oxygen Species; Sodium-Potassium-Exchanging ATPase; Spironolactone; Superoxide Dismutase; Transforming Growth Factor beta	2007