Compounds > spironolactone
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spironolactone and torsemide

spironolactone has been researched along with torsemide in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (22.22)18.2507
2000's5 (27.78)29.6817
2010's7 (38.89)24.3611
2020's2 (11.11)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Andricopulo, AD; Moda, TL; Montanari, CA1
Campillo, NE; Guerra, A; Páez, JA1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Kido, H; Ohtaki, Y; Uchida, T; Watanabe, M1
Knauf, H; Mutschler, E1
Applefeld, JJ; Dukes, GE; Hak, LJ; Kasmer, RJ; McClain, CJ; Wermeling, DP1
Elia, G; Fiaccadori, F; Pasetti, G; Pedretti, G; Pizzaferri, P1
Klues, HG; Martin, N; Ott, R1
Yamamoto, T; Yano, M1
Aizawa, Y; Harima, M; Kodama, M; Tachikawa, H; Tanaka, H; Thanikachalam, PV; Watanabe, K; Yamaguchi, K1
Jolobe, OM1
Schröder, S; Strobel, J1
Alvarez de la Rosa, D; El Moghrabi, S; Gravez, B; Jaisser, F; Jimenez-Canino, R; Messaoudi, S; Tarjus, A1
Nagappan, K; Sandeep Mannemala, S; Subramanian, V1
Arumugam, S; Harima, M; Karuppagounder, V; Nakamura, M; Sone, H; Sreedhar, R; Suzuki, H; Watanabe, K1
Paulus, R; Schmidt, B1
Bergler-Czop, B; Frątczak, A; Miziołek, B; Polak, K1

Reviews

2 review(s) available for spironolactone and torsemide

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Aldosterone antagonist therapy for chronic heart failure].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2005, Feb-10, Volume: 94, Issue:2

    Topics: Aldosterone; Chronic Disease; Death, Sudden, Cardiac; Diuretics; Eplerenone; Fibrosis; Heart Failure; Humans; Mineralocorticoid Receptor Antagonists; Myocardium; Randomized Controlled Trials as Topic; Spironolactone; Sulfonamides; Torsemide; Ventricular Remodeling

2005

Trials

3 trial(s) available for spironolactone and torsemide

ArticleYear
Liver cirrhosis with ascites: pathogenesis of resistance to diuretics and long-term efficacy and safety of torasemide.
    Cardiology, 1994, Volume: 84 Suppl 2

    Topics: Ascites; Diuretics; Drug Administration Schedule; Drug Therapy, Combination; Female; Furosemide; Humans; Liver Cirrhosis; Male; Middle Aged; Prospective Studies; Spironolactone; Sulfonamides; Torsemide; Xipamide

1994
A dose-response study of orally administered torsemide in patients with ascites due to cirrhosis.
    Alimentary pharmacology & therapeutics, 1994, Volume: 8, Issue:4

    Topics: Administration, Oral; Adult; Aged; Ascites; Body Weight; Cross-Over Studies; Diuretics; Dose-Response Relationship, Drug; Double-Blind Method; Electrolytes; Female; Humans; Liver Cirrhosis; Male; Middle Aged; Safety; Spironolactone; Sulfonamides; Torsemide

1994
Torasemide versus furosemide in cirrhosis: a long-term, double-blind, randomized clinical study.
    The Clinical investigator, 1993, Volume: 71, Issue:7

    Topics: Ascites; Diuretics; Double-Blind Method; Drug Therapy, Combination; Furosemide; Humans; Liver Cirrhosis; Spironolactone; Sulfonamides; Torsemide

1993

Other Studies

13 other study(ies) available for spironolactone and torsemide

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Diuretic profile of a novel loop diuretic torasemide in rats and dogs.
    Drugs under experimental and clinical research, 1991, Volume: 17, Issue:6

    Topics: Anesthesia; Animals; Diuretics; Dogs; Drug Therapy, Combination; Female; Male; Rats; Rats, Inbred Strains; Spironolactone; Sulfonamides; Torsemide

1991
[Idiopathic hypereosinophilia with cardiac involvement].
    Deutsche medizinische Wochenschrift (1946), 2004, Mar-12, Volume: 129, Issue:11

    Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Cardiomyopathy, Restrictive; Cardiotonic Agents; Diagnosis, Differential; Digoxin; Diuretics; Drug Therapy, Combination; Echocardiography, Doppler; Enalapril; Endomyocardial Fibrosis; Female; Humans; Hypereosinophilic Syndrome; Magnetic Resonance Imaging; Mineralocorticoid Receptor Antagonists; Mitral Valve Insufficiency; Patient Compliance; Prognosis; Spironolactone; Sulfonamides; Torsemide

2004
[Effects of various diuretics on cardiac function in rats with heart failure].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2009, Volume: 129, Issue:7

    Topics: Animals; Cytochrome P-450 CYP11B2; Disease Models, Animal; Diuretics; Furosemide; Heart Failure; Hemodynamics; Male; Myocardium; Rats; Rats, Inbred Lew; Spironolactone; Sulfonamides; Torsemide; Ventricular Remodeling

2009
Agents with antialdosterone properties should be the preferred diuretics for reducing hypertension related atrial fibrillation.
    European journal of internal medicine, 2010, Volume: 21, Issue:1

    Topics: Antihypertensive Agents; Atrial Fibrillation; Diuretics; Eplerenone; Humans; Hypertension; Spironolactone; Sulfonamides; Torsemide

2010
[Postpartum cardiomyopathy].
    Deutsche medizinische Wochenschrift (1946), 2011, Volume: 136, Issue:22

    Topics: Adrenergic beta-1 Receptor Antagonists; Adult; Angiotensin-Converting Enzyme Inhibitors; Anticoagulants; Antihypertensive Agents; Bisoprolol; Bromocriptine; Cardiomyopathies; Female; Heparin, Low-Molecular-Weight; Humans; Mineralocorticoid Receptor Antagonists; Postpartum Period; Radiography; Ramipril; Risk Factors; Spironolactone; Sulfonamides; Torsemide; Treatment Outcome

2011
The diuretic torasemide does not prevent aldosterone-mediated mineralocorticoid receptor activation in cardiomyocytes.
    PloS one, 2013, Volume: 8, Issue:9

    Topics: Active Transport, Cell Nucleus; Aldosterone; Animals; Cell Nucleus; Chlorocebus aethiops; COS Cells; Diuretics; Green Fluorescent Proteins; Humans; Immediate-Early Proteins; Luciferases; Mice; Microscopy, Confocal; Mineralocorticoid Receptor Antagonists; Myocytes, Cardiac; Orosomucoid; Plasminogen Activator Inhibitor 1; Protein Serine-Threonine Kinases; Rats; Receptors, Mineralocorticoid; Reverse Transcriptase Polymerase Chain Reaction; Serpins; Spironolactone; Sulfonamides; Tenascin; Torsemide; Transcriptional Activation

2013
Optimization and Validation of a Sensitive Method for HPLC-PDA Simultaneous Determination of Torasemide and Spironolactone in Human Plasma using Central Composite Design.
    Acta chimica Slovenica, 2015, Volume: 62, Issue:3

    Topics: Blood Chemical Analysis; Chromatography, High Pressure Liquid; Humans; Limit of Detection; Spironolactone; Sulfonamides; Time Factors; Torsemide

2015
Comparative evaluation of torasemide and spironolactone on adverse cardiac remodeling in a rat model of dilated cardiomyopathy.
    Cardiovascular therapeutics, 2017, Volume: 35, Issue:5

    Topics: Animals; Autoimmunity; Biomarkers; Cardiac Myosins; Cardiomyopathy, Dilated; Disease Models, Animal; Endoplasmic Reticulum Stress; Fibrosis; Heart Ventricles; Male; Mineralocorticoid Receptor Antagonists; Myocarditis; Rats, Inbred Lew; Sodium Potassium Chloride Symporter Inhibitors; Spironolactone; Sulfonamides; Torsemide; Ventricular Function, Left; Ventricular Remodeling

2017
90-year-old man • dyspnea • lower extremity edema • limitations in daily activities • Dx?
    The Journal of family practice, 2020, Volume: 69, Issue:9

    Topics: Activities of Daily Living; Aged, 80 and over; Diagnosis, Differential; Diuretics; Dyspnea; Edema; Female; Heart Failure; Humans; Lisinopril; Lower Extremity; Metoprolol; Obesity; Spironolactone; Torsemide

2020
Torasemide-induced Vascular Purpura in the Course of Eosinophilic Granulomatosis with Polyangiitis.
    Acta dermatovenerologica Croatica : ADC, 2022, Volume: 30, Issue:2

    Topics: Adolescent; Aged; Antibodies, Antineutrophil Cytoplasmic; Antibodies, Antinuclear; Antihypertensive Agents; Asthma; C-Reactive Protein; Churg-Strauss Syndrome; Eosinophilia; Female; Formoterol Fumarate; Granulomatosis with Polyangiitis; Humans; IgA Vasculitis; Inflammation; Ipratropium; Leukotriene Antagonists; Metoprolol; Mycophenolic Acid; Peroxidase; Prednisone; Purpura; Receptors, Fc; Rosuvastatin Calcium; Sodium Potassium Chloride Symporter Inhibitors; Spironolactone; Sulfanilamides; Torsemide

2022