Compounds > spironolactone
Page last updated: 2024-08-17

spironolactone and sirolimus

spironolactone has been researched along with sirolimus in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's4 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andricopulo, AD; Moda, TL; Montanari, CA1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Boldyreff, B; Braun, S; Lösel, R; Wehling, M1
Ji, J; Li, D; Lin, S; Lu, Z; Xu, Z; Yan, T; Zheng, Z1
Kream, RM; Ming, Y; Stefano, GB; Zhuang, Q1

Reviews

1 review(s) available for spironolactone and sirolimus

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

5 other study(ies) available for spironolactone and sirolimus

ArticleYear
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Aldosterone rapidly activates Src kinase in M-1 cells involving the mineralocorticoid receptor and HSP84.
    FEBS letters, 2004, Jul-16, Volume: 570, Issue:1-3

    Topics: Aldosterone; Animals; Blotting, Western; Cell Line; Dose-Response Relationship, Drug; Enzyme Activation; Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Kidney; Mice; Phosphorylation; Precipitin Tests; Receptors, Mineralocorticoid; Sirolimus; Spironolactone; src-Family Kinases; Time Factors; Tyrosine

2004
Spironolactone promotes autophagy via inhibiting PI3K/AKT/mTOR signalling pathway and reduce adhesive capacity damage in podocytes under mechanical stress.
    Bioscience reports, 2016, Volume: 36, Issue:4

    Topics: Autophagy; Autophagy-Related Protein 5; Cell Adhesion; Cell Line; Chromones; Diabetic Nephropathies; Down-Regulation; Humans; Integrin beta1; Microtubule-Associated Proteins; Morpholines; Phosphatidylinositol 3-Kinases; Podocytes; Proto-Oncogene Proteins c-akt; Receptors, Mineralocorticoid; Signal Transduction; Sirolimus; Spironolactone; Stress, Mechanical; TOR Serine-Threonine Kinases; Up-Regulation

2016
Anti-Diabetogenic Properties of Mineralocorticoid Receptor Antagonists: Implications for Enhanced Safety and Efficacy of Post-Transplantation Pharmacotherapies.
    Medical science monitor : international medical journal of experimental and clinical research, 2019, Feb-10, Volume: 25

    Topics: Calcineurin; Calcineurin Inhibitors; Cyclosporine; Diabetes Complications; Diabetes Mellitus; Everolimus; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Transplantation; Mineralocorticoid Receptor Antagonists; Sirolimus; Spironolactone; Tacrolimus; Transplantation Tolerance

2019