Compounds > spironolactone

Page last updated: 2024-08-17

spironolactone and sc70303

spironolactone has been researched along with sc70303 in 5 studies

Research

Studies (5)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	4 (80.00)	29.6817
2010's	1 (20.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Cook, CS; Fischer, JS; Zhang, L	1
Cook, CS; Zhang, L	2
Ames, GB; Cook, CS; Fischer, J; Levin, S; Zhang, J; Zhang, L	1
Chiba, K; Mori, Y; Ogata, H; Takahashi, H	1

Trials

1 trial(s) available for spironolactone and sc70303

Article	Year
A population approach to eplerenone pharmacokinetics and saturable protein binding. Drug metabolism and pharmacokinetics, 2010, Volume: 25, Issue:6 Topics: Area Under Curve; Asian People; Clinical Trials, Phase I as Topic; Eplerenone; Humans; Mineralocorticoid Receptor Antagonists; Models, Biological; Protein Binding; Spironolactone; White People	2010

Other Studies

4 other study(ies) available for spironolactone and sc70303

Article	Year
Absorption and disposition of a selective aldosterone receptor antagonist, eplerenone, in the dog. Pharmaceutical research, 2000, Volume: 17, Issue:11 Topics: Administration, Oral; Administration, Rectal; Animals; Body Fluid Compartments; Dogs; Eplerenone; Feces; Female; Gastric Mucosa; Injections, Intravenous; Intestinal Absorption; Intestinal Mucosa; Male; Mineralocorticoid Receptor Antagonists; Mouth Mucosa; Spironolactone; Stomach	2000
Atypical dose-route-dependent food effects of eplerenone in the dog: presence of food effects following intravenous dosing and lack of food effects of following oral dosing. Journal of pharmaceutical sciences, 2002, Volume: 91, Issue:3 Topics: Administration, Oral; Animals; Area Under Curve; Dogs; Eplerenone; Food-Drug Interactions; Infusions, Intravenous; Liver; Mass Spectrometry; Mineralocorticoid Receptor Antagonists; Portal Vein; Spironolactone	2002
Interconversion pharmacokinetics of eplerenone, a selective aldosterone blocker, and its lactone-ring open form. Journal of pharmaceutical sciences, 2002, Volume: 91, Issue:6 Topics: Aldosterone; Animals; Dogs; Eplerenone; Female; Injections, Intravenous; Lactones; Models, Animal; Spironolactone	2002
Single- and repeated-dose pharmacokinetics of eplerenone, a selective aldosterone receptor blocker, in rats. Xenobiotica; the fate of foreign compounds in biological systems, 2003, Volume: 33, Issue:3 Topics: Administration, Oral; Animals; Biotransformation; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Eplerenone; Feces; Female; Half-Life; In Vitro Techniques; Injections, Intravenous; Male; Microsomes, Liver; Mineralocorticoid Receptor Antagonists; Mixed Function Oxygenases; Rats; Rats, Sprague-Dawley; Sex Factors; Spironolactone; Subcellular Fractions	2003