Compounds > spironolactone
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spironolactone and quinapril

spironolactone has been researched along with quinapril in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (10.00)18.2507
2000's2 (20.00)29.6817
2010's7 (70.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Benetos, A; Lacolley, P; Safar, ME1
Godo, M; Gross, ML; Hamar, P; Kokeny, G; Mózes, M; Nemeth, Z; Ritz, E; Rosivall, L1
Frohlich, ED; Susic, D; Varagic, J1
Kanorskiy, SG; Pokrovskiy, VM; Tregubov, VG1
Aleksiejczuk, M; Chabielska, E; Gromotowicz-Poplawska, A; Marcinczyk, N; Mikita, J; Stankiewicz, A; Szemraj, J1

Reviews

1 review(s) available for spironolactone and quinapril

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

9 other study(ies) available for spironolactone and quinapril

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Prevention of aortic fibrosis by spironolactone in spontaneously hypertensive rats.
    Arteriosclerosis, thrombosis, and vascular biology, 1997, Volume: 17, Issue:6

    Topics: Animals; Aorta, Thoracic; Blood Pressure; Collagen; Fibrosis; Heart Rate; Hypertension; Isoquinolines; Mineralocorticoid Receptor Antagonists; Quinapril; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Spironolactone; Tetrahydroisoquinolines; Vascular Diseases

1997
Increased renoprotection with ACE inhibitor plus aldosterone antagonist as compared to monotherapies--the effect on podocytes.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2009, Volume: 24, Issue:12

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Drug Therapy, Combination; Kidney Diseases; Male; Mineralocorticoid Receptor Antagonists; Podocytes; Quinapril; Rats; Rats, Sprague-Dawley; Spironolactone; Tetrahydroisoquinolines

2009
Cardiovascular effects of inhibition of renin-angiotensin-aldosterone system components in hypertensive rats given salt excess.
    American journal of physiology. Heart and circulatory physiology, 2010, Volume: 298, Issue:4

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cardiomyopathies; Cardiovascular System; Eplerenone; Hypertension; Hypertrophy; Kidney; Male; Mineralocorticoid Receptor Antagonists; Quinapril; Rats; Rats, Inbred SHR; Receptors, Mineralocorticoid; Regional Blood Flow; Renin-Angiotensin System; Sodium Chloride, Dietary; Spironolactone; Tetrahydroisoquinolines; Tetrazoles; Ventricular Dysfunction, Left

2010
[Regulatory Adaptive Status in Assessment of Efficacy of Pharmacotherapy and Prognostication of Complications in Functional Class III Chronic Heart Failure].
    Kardiologiia, 2016, Volume: 56, Issue:1

    Topics: Aged; Benzazepines; Cardiovascular Agents; Chronic Disease; Echocardiography; Exercise Test; Female; Heart Failure; Humans; Hypertension; Ivabradine; Male; Metoprolol; Middle Aged; Quinapril; Random Allocation; Spironolactone; Tetrahydroisoquinolines; Treatment Outcome; Ventricular Function, Left

2016
Beneficial effect of combined spironolactone and quinapril treatment on thrombosis and hemostasis in 2K1C hypertensive rats.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2018, Volume: 69, Issue:2

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Antigens, Tumor-Associated, Carbohydrate; Aorta; Bleeding Time; Blood Pressure; Carboxypeptidase B2; Collagen; Drug Therapy, Combination; Hypertension; Male; Mineralocorticoid Receptor Antagonists; Plasminogen Activator Inhibitor 1; Platelet Adhesiveness; Quinapril; Rats, Wistar; Renin; Spironolactone; Tetrahydroisoquinolines; Tissue Plasminogen Activator; Venous Thrombosis

2018