spironolactone has been researched along with pregnenolone in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (89.66) | 18.7374 |
| 1990's | 1 (3.45) | 18.2507 |
| 2000's | 2 (6.90) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellavance, E; Luu-The, V; Poirier, D | 1 |
| Kourounakis, P; Ship, S | 1 |
| Gangnerau, MN; Picon, R; Rouiller, V | 1 |
| Bernier, M; Darbeida, H; Durand, P; Penhoat, A; Saez, JM | 1 |
| Conney, AH; Kovacs, K; Kuntzman, R; Solymoss, B; Somogyi, A | 1 |
| Selye, H; Szabo, S; Taché, Y | 1 |
| Selye, H | 5 |
| Dardachti, D; Garg, BD; Khandekar, JD; Kovacs, K; Tuchweber, B | 1 |
| Solymoss, B; Toth, S; Werringloer, J | 1 |
| Solymoss, B; Zsigmond, G | 1 |
| Husztik, E; Lazar, G; Szabo, S | 1 |
| Kourounakis, P; Selye, H; Szabo, S | 1 |
| Lazar, G; Szabo, S | 1 |
| Radzialowski, FM | 1 |
| Gillette, JR; Menard, RH; Stripp, B | 1 |
| Selye, H; Szabo, S | 1 |
| Mécs, I; Selye, H; Szabo, S | 1 |
| Garg, BD; Khandekar, JD; Kovacs, K; Tuchweber, B | 2 |
| Blascheck, JA; Garg, BD; Kovacs, K | 1 |
| Jelinek, J; Krajny, M; Selye, H | 1 |
| Adashi, EY; Hsueh, AJ; Tucker, EM | 1 |
| Brimer, C; Schuetz, EG; Schuetz, JD | 1 |
| Canosa, LF; Ceballos, NR | 1 |
| COOK, K; FRENKEL, JK; GRADY, HJ; PENDLETON, SK | 1 |
1 review(s) available for spironolactone and pregnenolone
| Article | Year |
|---|---|
Protection by catatoxic steroids against cyclophosphamide-induced organ lesions.
Topics: Adrenal Glands; Animals; Body Weight; Bone Marrow; Cyclophosphamide; Desoxycorticosterone; Enzyme Induction; Estradiol; Ethylestrenol; Female; Ketones; Microsomes, Liver; Mortality; Oxandrolone; Phenobarbital; Prednisolone; Pregnancy; Pregnanediones; Pregnanes; Pregnenolone; Progesterone; Rats; Spironolactone; Thyroxine; Triamcinolone | 1970 |
28 other study(ies) available for spironolactone and pregnenolone
| Article | Year |
|---|---|
Potent and selective steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 7, an enzyme that catalyzes the reduction of the key hormones estrone and dihydrotestosterone.
Topics: 17-Hydroxysteroid Dehydrogenases; Androstane-3,17-diol; Androstanes; Biocatalysis; Cell Line; Dihydrotestosterone; Enzyme Inhibitors; Estradiol; Estrone; Humans; Inhibitory Concentration 50; Oxidation-Reduction; Substrate Specificity | 2009 |
Influence of combined treatment with pregnenolone-16alpha-carbonitrile and spironolactone or phenobarbital on drug metabolism in rats.
Topics: Animals; Dose-Response Relationship, Drug; Female; Microsomes, Liver; Nitriles; Phenobarbital; Pregnenolone; Rats; Spironolactone; Zoxazolamine | 1977 |
Production of C21 steroids in rat fetal ovaries.
Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Bucladesine; Cycloheximide; Female; Hydroxycholesterols; Kinetics; Organ Culture Techniques; Ovary; Pregnenolone; Progesterone; Rats; Rats, Inbred Strains; Spironolactone; Steroid 17-alpha-Hydroxylase | 1988 |
Inhibition of hormonal-induced cAMP and steroid production by inhibitors of pregnenolone metabolism in adrenal and Leydig cells.
Topics: Adrenal Glands; Animals; Carrier Proteins; Cattle; Cells, Cultured; Cholesterol; Colforsin; Cyclic AMP; Dihydrotestosterone; Endoribonucleases; Intracellular Signaling Peptides and Proteins; Leydig Cells; Male; Phosphoprotein Phosphatases; Pregnenolone; Proteins; RNA-Binding Proteins; Sheep; Spironolactone; Steroids; Swine; Tetrahydronaphthalenes | 1988 |
Suppression of 7,12-dimethylbenz( )anthracene-produced adrenal necrosis by steroids capable of inducing aryl hydrocarbon hydroxylase.
Topics: Adrenal Gland Diseases; Androstanes; Animals; Benz(a)Anthracenes; Benzopyrenes; Betamethasone; Dexamethasone; Enzyme Induction; Ethylestrenol; Female; Fluorescence; Fluorine; Hydroxylation; Ketosteroids; Liver; Mixed Function Oxygenases; Necrosis; Phenobarbital; Polycyclic Compounds; Pregnenolone; Rats; Spironolactone | 1971 |
Interruption of pregnancy by various steroids.
Topics: Abortion, Induced; Anabolic Agents; Animals; Cholesterol; Dehydroepiandrosterone; Dexamethasone; Digitoxin; Estradiol; Ethylestrenol; Female; Indomethacin; Oxandrolone; Phenobarbital; Prednisolone; Pregnancy; Pregnenolone; Progesterone; Rats; Spironolactone; Steroids; Triamcinolone | 1971 |
Steroids influencing the toxicity of L-tyrosine.
Topics: Adrenal Cortex Hormones; Animals; Cholesterol; Desoxycorticosterone; Diet; Edema; Ethylestrenol; Eye; Eyelids; Female; Oxandrolone; Pancreas; Poisoning; Prednisolone; Pregnanediones; Pregnenolone; Rats; Spironolactone; Thyroxine; Triamcinolone; Tyrosine | 1971 |
Effect of cycloheximide on the ultrastructural changes produced by spironolactone and pregnenolone-16 alpha-carbonitrile in the rat liver.
Topics: Animals; Cycloheximide; Endoplasmic Reticulum; Female; Liver; Microscopy, Electron; Microsomes, Liver; NADP; Nitriles; Pregnenolone; Rats; Spironolactone | 1971 |
The influence of pregnenolone-16 -carbonitrile on hepatic mixed-function oxygenases.
Topics: Animals; Carbon Isotopes; Cytochromes; Enzyme Induction; Female; Half-Life; Liver; Metabolic Clearance Rate; Microsomes, Liver; NADP; Nitriles; Organ Size; Oxidoreductases; Pentobarbital; Pregnenolone; Proteins; Rats; Spironolactone; Stimulation, Chemical | 1971 |
[Anticatatoxic hormones].
Topics: Animals; Desoxycorticosterone; Digitoxin; Drug Antagonism; Drug Synergism; Estradiol; Female; Glucocorticoids; Indomethacin; Mineralocorticoids; Nitriles; Pregnanediones; Pregnenolone; Progesterone; Rats; Rats, Inbred Strains; Spironolactone; Thyroxine; Triamcinolone | 1972 |
Effect of spironolactone, pregnenolone-16 -carbonitrile and cortisol on the metabolism and biliary excretion of sulfobromophthalein and phenol-3,6-dibromophthalein disulfonate in rats.
Topics: Animals; Biliary Tract; Bromine; Female; Glutathione; Hydrocortisone; Kinetics; Liver; Nitriles; Organ Size; Phenobarbital; Phenolphthaleins; Pregnenolone; Rats; Rats, Inbred Strains; Spectrophotometry; Spironolactone; Sulfobromophthalein | 1972 |
The experimental production of hemorrhagic lesions in the rat adrenal, liver and lung by basic polyglutamic acid derivatives.
Topics: Adrenal Gland Diseases; Adrenal Glands; Animals; Chemical and Drug Induced Liver Injury; Ethylestrenol; Female; Glutamates; Hemorrhage; Hypophysectomy; Liver; Liver Diseases; Lung; Lung Diseases; Nitriles; Pregnenolone; Rats; Spironolactone; Triamcinolone | 1972 |
Protection by catatoxic steroids, phenobarbital and diphenylhydantoin against methaqualone intoxication.
Topics: Androstenes; Animals; Enzyme Induction; Ethylestrenol; Female; Hydroxysteroids; Ketosteroids; Methaqualone; Movement Disorders; Nitriles; Norsteroids; Oxandrolone; Phenobarbital; Phenytoin; Pregnenolone; Propionates; Rats; Spironolactone; Steroids | 1972 |
The Harry G. Armstrong Lecture. Stress and aerospace medicine.
Topics: Adaptation, Biological; Adrenal Glands; Aerospace Medicine; Ethylestrenol; Glucocorticoids; Growth Hormone; Homeostasis; Humans; Immunity; Inflammation; Pregnenolone; Research; Space Flight; Spironolactone; Stress, Physiological | 1973 |
Effect of hypophysectomy and catatoxic steroids on thioacetamide-induced adrenal lesions in rats.
Topics: Acetamides; Adrenal Gland Diseases; Adrenal Glands; Anabolic Agents; Animals; Dexamethasone; Ethylestrenol; Female; Hemorrhage; Hypophysectomy; Necrosis; Oxandrolone; Pregnenolone; Rats; Spironolactone | 1973 |
Effect of spironolactone and pregnenolone-16alpha carbonitrile on bilirubin metabolism and plasma levels in male and female rats.
Topics: Animals; Bilirubin; Female; Glucuronates; Liver; Male; Nitriles; Pregnenolone; Rats; Sex Factors; Spironolactone; Time Factors; Transferases | 1973 |
Spironolactone and testicular cytochrome P-450: decreased testosterone formation in several species and changes in hepatic drug metabolism.
Topics: Animals; Carbon Radioisotopes; Cytochrome P-450 Enzyme System; Cytochromes; Dogs; Female; Guinea Pigs; Heme; Liver; Male; Methyltestosterone; Mice; Microsomes; Pregnenolone; Progesterone; Rabbits; Rats; Spironolactone; Steroid Hydroxylases; Testis; Testosterone | 1974 |
Protection against haloperidol by catatoxic steroids.
Topics: Animals; Central Nervous System; Drug Antagonism; Drug Synergism; Ethylestrenol; Female; Haloperidol; Ketones; Nitriles; Oxandrolone; Phenobarbital; Prednisolone; Pregnanes; Pregnenolone; Progesterone; Rats; Spironolactone; Thyroxine; Triamcinolone | 1972 |
Protection by catatoxic steroids and related compounds against proscillaridin intoxication.
Topics: Anabolic Agents; Androstanes; Animals; Bufanolides; Digitoxin; Ethylestrenol; Female; Glucocorticoids; Hydroxysteroids; Ketosteroids; Phenobarbital; Pregnanes; Pregnenolone; Propionates; Rats; Rats, Inbred Strains; Seizures; Spironolactone; Thyroxine | 1972 |
Effect of phenobarbital and steroids on phalloidin toxicity in rats.
Topics: Animals; Estradiol; Ethylestrenol; Female; Glucocorticoids; Liver; Microsomes, Liver; Mycotoxins; Nitriles; Phenobarbital; Pregnenolone; Progesterone; Rats; Rats, Inbred Strains; Spironolactone; Steroids; Toxins, Biological | 1972 |
A comparative ultrastructural study on drug-induced proliferation of smooth-surfaced endoplasmic reticulum in hepatocytes.
Topics: Animals; Endoplasmic Reticulum; Female; Liver; Methylcholanthrene; Microscopy, Electron; Organoids; Phenobarbital; Pregnenolone; Rats; Spironolactone | 1971 |
Influence of dactinomycin on the ultrastructural changes induced in rat hepatocytes by spironolactone and pregnelonone-16 -carbonitrile.
Topics: Animals; Dactinomycin; Endoplasmic Reticulum; Female; Injections, Intravenous; Liver; Nitriles; Pregnenolone; Rats; Spironolactone | 1971 |
Effect of catatoxic steroids upon established morbid changes.
Topics: Animals; Digitoxin; Female; Indomethacin; Intestine, Small; Nitriles; Peritonitis; Poisoning; Pregnenolone; Rats; Seizures; Spironolactone | 1971 |
Prevention of digitoxin poisoning by various steroids.
Topics: Anabolic Agents; Androstanes; Animals; Body Weight; Desoxycorticosterone; Digitoxin; Diuretics; Estradiol; Ethisterone; Ethylestrenol; Female; Fluoxymesterone; Hydrocortisone; Ketones; Methyltestosterone; Nandrolone; Norethandrolone; Norethynodrel; Organ Size; Oxandrolone; Oxymetholone; Poisoning; Pregnanes; Pregnenolone; Progesterone; Pyrazines; Rats; Spironolactone; Testosterone; Triamterene | 1969 |
Direct regulation of rat testicular steroidogenesis by neurohypophysial hormones. Divergent effects on androgen and progestin biosynthesis.
Topics: Animals; Cells, Cultured; Chorionic Gonadotropin; Cyanoketone; Hypophysectomy; Kinetics; Male; Pituitary Hormones, Posterior; Pregnenolone; Progesterone; Rats; Rats, Inbred Strains; Spironolactone; Testis; Testosterone; Vasotocin | 1984 |
Environmental xenobiotics and the antihormones cyproterone acetate and spironolactone use the nuclear hormone pregnenolone X receptor to activate the CYP3A23 hormone response element.
Topics: Androgen Antagonists; Animals; Aryl Hydrocarbon Hydroxylases; Cell Line; Cell Nucleus; Cyproterone Acetate; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Environmental Pollutants; Enzyme Activation; Mice; Mineralocorticoid Receptor Antagonists; Pregnane X Receptor; Pregnenolone; Promoter Regions, Genetic; Rats; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Response Elements; Spironolactone; Swine; Transcription, Genetic; Transfection; Xenobiotics | 1998 |
Effects of different steroid-biosynthesis inhibitors on the testicular steroidogenesis of the toad Bufo arenarum.
Topics: 17-Hydroxysteroid Dehydrogenases; Androgen Antagonists; Androgens; Animals; Bufonidae; Cholestenone 5 alpha-Reductase; Cyanoketone; Dehydroepiandrosterone; Enzyme Inhibitors; Finasteride; Male; Oxidoreductases; Pregnenolone; Spironolactone; Steroid 17-alpha-Hydroxylase; Testis; Testosterone | 2001 |
EFFECTS OF HORMONES ON ADRENOCORTICAL SECRETION OF GOLDEN HAMSTERS.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Animals; Cricetinae; Diethylstilbestrol; Endotoxins; Enzyme Inhibitors; Estrogens; Hormones; Hydrocortisone; Hypophysectomy; Hypothermia; Hypothermia, Induced; Mesocricetus; Metabolism; Metyrapone; Mineralocorticoid Receptor Antagonists; Nitrogen Mustard Compounds; Pharmacology; Pregnenolone; Progestins; Propiophenones; Research; Spironolactone; Stress, Physiological | 1965 |