Page last updated: 2024-08-17

spironolactone and monocrotaline

spironolactone has been researched along with monocrotaline in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Buhler, DR; Chung, WG1
Wang, Y; Wu, Q; Zhang, M; Zhong, B; Zhu, T1

Other Studies

4 other study(ies) available for spironolactone and monocrotaline

ArticleYear
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
The effect of spironolactone treatment on the cytochrome P450-mediated metabolism of the pyrrolizidine alkaloid senecionine by hepatic microsomes from rats and guinea pigs.
    Toxicology and applied pharmacology, 1994, Volume: 127, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Female; Guinea Pigs; Isoenzymes; Male; Microsomes, Liver; Monocrotaline; Oxidation-Reduction; Oxidoreductases, N-Demethylating; Pyrrolizidine Alkaloids; Rats; Rats, Sprague-Dawley; Species Specificity; Spironolactone

1994
Aldosterone Contributed to Pulmonary Arterial Hypertension Development via Stimulating Aquaporin Expression and Pulmonary Arterial Smooth Muscle Cells Proliferation.
    Pharmacology, 2020, Volume: 105, Issue:7-8

    Topics: Aldosterone; Animals; Aquaporin 1; beta Catenin; Cell Proliferation; Disease Models, Animal; Female; Mineralocorticoid Receptor Antagonists; Monocrotaline; Myocytes, Smooth Muscle; Pulmonary Arterial Hypertension; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Spironolactone

2020