spironolactone has been researched along with mifepristone in 173 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (4.62) | 18.7374 |
| 1990's | 50 (28.90) | 18.2507 |
| 2000's | 60 (34.68) | 29.6817 |
| 2010's | 51 (29.48) | 24.3611 |
| 2020's | 4 (2.31) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Arias, DA; Barbieri, LR; Berrodin, TJ; Bigelis, R; Chang, LP; Luckman, SW; McDonald, LA; Roll, DM; Singh, MP; Yudt, MR | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Kalish, EE; Logvinenko, NS; Solenov, EI; Svitasheva, NG | 1 |
| Hu, SB; Lightman, SL; Tannahill, LA | 1 |
| Currie, MG; Lanier-Smith, KL | 1 |
| Funder, JW; Myles, K; Pearce, PT; Roy, LP | 1 |
| de Jong, W; de Kloet, ER; van den Berg, DT; van Dijken, HH | 1 |
| Bloemers, M; de Kloet, ER; Ratka, A; Sutanto, W | 1 |
| Jazayeri, A; Meyer, WJ | 1 |
| Davda, MM; Kang, CG; Luttge, WG; Rupp, ME | 1 |
| Clore, JN; Estep, H; Ross-Clunis, H; Watlington, CO | 1 |
| Duncan, RL; Grogan, WM; Kramer, LB; Watlington, CO | 1 |
| Capek, K; Pácha, J; Popp, M | 1 |
| De Kloet, ER; De Kock, S; Schild, V; Veldhuis, HD | 1 |
| Eloy, L; Ganeval, D; Grünfeld, JP; Moura, AM; Ramos-Frendo, B; Worcel, M | 1 |
| Magariños, AM; McEwen, BS; Pavlides, C; Watanabe, Y | 1 |
| Funder, J; Head, G; Young, M | 1 |
| Li, P; Xue, LM; Zhu, DN | 1 |
| Cosen-Binker, L; de Kloet, ER; De Nicola, AF; Gonzalez, S; Grillo, CA; McEwen, BS; Vallee, SM | 1 |
| Engel, JA; Eriksson, CJ; Fahlke, C; Hansen, S; Hård, E | 1 |
| Dagnault, A; Deshaies, Y; Richard, D | 2 |
| de Kloet, ER; Fluttert, M; Oitzl, MS | 1 |
| Rose, SP; Sandi, C | 1 |
| Auzou, G; Balaguer, P; Jausons-Loffreda, N; Pons, M | 1 |
| Holsboer, F; Lauer, C; Pollmächer, T; Wiedemann, K | 1 |
| Boadle-Biber, MC; Corley, KC; Krieg, RJ; Phan, TH; Singh, VB | 1 |
| Ricketts, ML; Stewart, PM; Whorwood, CB | 1 |
| Edwards, CR; Sang, KS; Walker, BR; Williams, BC | 1 |
| Dean, RG; Edwards, GL; Martin, RJ; White, BD | 1 |
| Amir, I; Shohami, E; Weidenfeld, J | 1 |
| Bohus, B; de Boer, SF; de Kloet, ER; Korte, SM | 1 |
| Asano, Y; Kawakami, K; Muto, S; Nagano, K; Nemoto, J; Ohtaka, A; Watanabe, Y; Yamaki, M | 1 |
| de Kloet, ER; Meijer, OC | 1 |
| Bohus, B; De Kloet, ER; Koob, GF; Korte, SM; Korte-Bouws, GA | 1 |
| Fahlke, C; Hansen, S; Hård, E | 1 |
| Cooney, JM; Dinan, TG | 1 |
| Crabbé, J; Lyoussi, B | 1 |
| Costall, B; Murphy, D; Smythe, JW; Timothy, C | 1 |
| Feldman, S; Itzik, A; Weidenfeld, J | 1 |
| Aggerbeck, M; Barouki, R; Lombès, M; Massaad, C; Rafestin-Oblin, ME | 1 |
| Knepper, MA; Nolan, PJ; Packer, RK | 1 |
| de Kloet, ER; Oitzl, MS; van Haarst, AD | 1 |
| Cordero, MI; Sandi, C | 1 |
| Costall, B; Murphy, D; Smythe, JW | 1 |
| Barker, KS; Davis, AT; Rollins-Smith, LA | 1 |
| Pácha, J; Zemanová, Z | 1 |
| Cole, MA; Kalman, BA; Kim, PJ; Spencer, RL | 2 |
| Bohus, B; Buwalda, B; Douma, BR; Korte, SM; la Fleur, SE; Luiten, PG | 1 |
| Aouizerate, B; Barrot, M; Le Moal, M; Marinelli, M; Piazza, PV | 1 |
| Asano, Y; Ebata, S; Kawakami, K; Muto, S; Nemoto, J | 1 |
| Bitran, D; Dowd, JA; Dugan, MM; Renda, P; Shiekh, M | 1 |
| Daisley, JN; Loscertales, M; Rose, SP; Sandi, C | 1 |
| Fraser, T; Li, M; Wen, C; Whitworth, JA | 1 |
| Cameron, SA; Dutia, MB | 1 |
| Buwalda, B; Douma, BR; Jansen, K; Korte, SM; Luiten, PG; Van der Zee, EA | 1 |
| Amemiya, M; Asano, Y; Ebata, S; Muto, S; Nemoto, J; Okada, K; Saito, T | 1 |
| Grafte-Faure, S; Leveque, C; Norris, V; Soria, C; Vannier, JP; Vasse, M | 1 |
| Harris, RC; McKanna, JA; Zhang, MZ | 1 |
| Fluharty, SJ; Ma, LY; McEwen, BS; Sakai, RR | 1 |
| Asano, Y; Ebata, S; Muto, S; Okada, K; Saito, T | 1 |
| Copolov, D; Huang, W; Lee, D; Lim, AT; Wang, L | 1 |
| Cluzeaud, F; Le Menuet, D; Lombès, M; Penfornis, P; Viengchareun, S; Zennaro, MC | 1 |
| Cole, MA; Kalman, BA; Lowrey, MJ; Pace, TW; Spencer, RL; Topczewski, F | 1 |
| Deak, T; Fleshner, M; Maier, SF; Nguyen, KT; Watkins, LR | 1 |
| Herman, JP; McCullers, DL | 1 |
| Calvo, N; Volosin, M | 1 |
| De Kloet, ER; Fluttert, MF; Sibug, RM; Van Acker, SA | 1 |
| Herman, JP; McCullers, DL; Scheff, SW; Sullivan, PG | 2 |
| Desforges, PR; Gilmour, KM; Sloman, KA | 1 |
| Bousquet, J; Harvey, BJ; Mainprice, B; Urbach, V; Walsh, DE | 1 |
| Coca-Prados, M; Hewison, M; Hughes, SV; Murray, PI; Rauz, S; Stewart, PM; Walker, EA | 1 |
| Bevington, A; Brown, J; Butler, H; Cheng, MK; Pickering, W; Walls, J | 1 |
| Christ, M; Falkenstein, E; Feuring, M; Hafner, M; Kellner, M; Lösel, R; Peiter, A; Wehling, M | 1 |
| Aoki, K; Kaburagi, Y; Kikuchi, T; Mori, Y; Sekihara, H; Yamashita, R; Yasuda, K | 1 |
| Born, J; Dimitrov, S; Fehm, HL; Lange, T | 1 |
| Koenig, HN; Olive, MF | 1 |
| Grosell, M; McDonald, MD; Walsh, PJ; Wood, CM | 1 |
| Lorell, BH; Nakayama, M; O'Connell, TD; Okoshi, K; Okoshi, MP; Schuldt, AJ; Simpson, PC; Yan, X | 1 |
| Beck, KD; Moldow, RL; Servatius, RJ; Weaver, S | 1 |
| Harris, BR; Little, HJ; Littleton, JM; Mulholland, PJ; Prendergast, MA; Self, RL | 1 |
| Barrère-Lemaire, S; Bénitah, JP; Lalevée, N; Nargeot, J; Perrier, E; Rebsamen, MC; Rossier, MF | 1 |
| Curtis, JT; Wang, Z | 1 |
| Chen, Y; Qi, A; Xiao, L | 1 |
| Keir, KR; Schulte, PM; Scott, GR | 1 |
| Herbert, J; Wong, EY | 1 |
| Hirata, Y; Hirono, Y; Iwashima, F; Minami, I; Sakai, H; Sakurada, M; Sato, R; Sugiyama, T; Suzuki, N; Tateno, T; Tsuchiya, K; Yoshimoto, T | 1 |
| Hausberg, M; Kusche, K; Ludwig, T; Oberleithner, H; Riethmüller, C; Schillers, H; Schwab, A; Shahin, V; Stock, C | 1 |
| Frøkiaer, J; Knepper, MA; Kwon, TH; Nielsen, J; Nielsen, S | 1 |
| Barnaby, R; Coutermarsh, B; Durant, L; Gabor, K; Hamilton, JW; Hand, E; Karlson, KH; Lankowski, A; Sato, JD; Shaw, JR; Stanton, BA; Stanton, CR; Thibodeau, R | 1 |
| Glavas, MM; Weinberg, J; Yu, WK | 1 |
| Duke, BJ; Eaton, DC; Holzman, JL; Kemendy, AE; Liu, L | 1 |
| Greenwood-Van Meerveld, B; Myers, B | 2 |
| Awasthi, N; Gupta, V; Wagner, BJ | 1 |
| Bussolino, D; Calfa, G; Molina, VA | 1 |
| Ligtenberg, JJ; Meertens, JH; Monteban-Kooistra, WE; Oosterhuis, JK; Tulleken, JE; van den Berg, G; Zijlstra, JG | 1 |
| Fuller, PJ; Funder, JW; Morgan, J; Rickard, AJ; Young, MJ | 1 |
| Bunda, S; Hinek, A; Liu, K; Liu, P; Wang, Y | 1 |
| Khaksari, M; Rashidy-Pour, A; Vafaei, AA | 1 |
| Hopfer, U; Jose, PA; Pinho, MJ; Pinto, V; Soares-da-Silva, P | 1 |
| Koizumi, M; Yada, T | 1 |
| Chepkova, AN; Haas, HL; Sergeeva, OA | 1 |
| Budziszewska, B; Chocyk, A; Grzegorzewska, M; Hess, G; Maćkowiak, M; Wedzony, K | 1 |
| Leite-Dellova, DC; Malnic, G; Mello-Aires, M; Oliveira-Souza, M | 1 |
| Foreman, RD; Greenwood-Van Meerveld, B; Venkova, K | 1 |
| Bagamasbad, P; Bonett, RM; Denver, RJ; Hu, F | 1 |
| Mattsson, C; Olsson, T; Reynolds, RM; Simonyte, K; Walker, BR | 1 |
| Aznar, S; Brandwein, C; Chourbaji, S; Gass, P; Halldin, C; Kirkegaard, L; Knudsen, GM; Krey, G; Marcussen, AB; Ridder, S; Thomsen, MS; Trajkovska, V | 1 |
| Brande-Lavridsen, N; Engelund, M; Jørgensen, C; Madsen, SS; Olesen, JH; Tipsmark, CK | 1 |
| Wang, CC; Wang, SJ | 1 |
| Bailey, MA; Kenyon, CJ; Mullins, JJ | 1 |
| Balado, E; Deroche-Gamonet, V; Fiancette, JF; Piazza, PV | 1 |
| Basic, D; Schjolden, J; Winberg, S | 1 |
| Funder, JW; Loan Le, TY; Mardini, M; Mihailidou, AS | 1 |
| Fan, Y; Sun, Z; Zha, Q; Zhu, MY | 1 |
| Bärfacker, L; Heidland, A; Kolkhof, P; Queisser, N; Schäfer, S; Schupp, N; Stopper, H; Wolf, M | 1 |
| Glazier, JD; Greenwood, SL; Sibley, CP; Speake, PF | 1 |
| Cao, J; Duan, TT; Mao, RR; Tan, JW; Tian, M; Xu, L; Zhou, QX | 1 |
| Bakker, EH; Berger, S; Joëls, M; Krugers, HJ; Oitzl, M; Velzing, EH; Zhou, M | 1 |
| de Gortari, P; López-Rubalcava, C; Mostalac-Preciado, CR | 1 |
| Gu, X; Liu, C; Ma, Q; Ma, Z; Peng, L; Song, L; Sun, X; Yang, D; Zheng, Y; Zhu, B | 1 |
| Danielewicz, J; Hess, G; Spyrka, J | 1 |
| Godfrey, V; Lyles, GA; Martin, AL; Struthers, AD | 1 |
| Chasiotis, H; Kelly, SP | 1 |
| Esbaugh, AJ; Gilmour, KM; McDonald, MD; Rodela, TM; Walsh, PJ | 1 |
| Briones, AM; Callera, GE; He, Y; Montezano, AC; Nguyen Dinh Cat, A; Touyz, RM; Yogi, A | 1 |
| Gan, WB; Liston, C | 1 |
| Joëls, M; Kindt, M; Krugers, HJ; Zhou, M | 1 |
| Jadavji, NM; Metz, GA; Supina, RD | 1 |
| Braga-Sobrinho, C; Leite-Dellova, DC; Mello-Aires, M | 1 |
| Cain, BD; Gumz, ML; Stow, LR; Voren, GE; Wingo, CS | 1 |
| Maggio, N; Segal, M | 1 |
| Funahashi, T; Hirata, A; Hiuge-Shimizu, A; Maeda, N; Nakatsuji, H; Okada, T; Shimomura, I | 1 |
| Cole, MA; Kalman, BA; Pace, TW; Spencer, RL; Ward, G | 1 |
| Capuano, V; Ferron, L; Renaud, JF; Ruchon, Y; Sankhe, S | 1 |
| Amano, T; Nakatani, Y; Takeda, H; Tsuji, M | 1 |
| Howland, JG; Thai, CA; Zhang, Y | 1 |
| Besedovsky, L; Born, J; Lange, T; Rimmele, U | 1 |
| Amano, T; Nakatani, Y; Takeda, H | 2 |
| Chen, P; Fan, Y; Li, Y; Zhu, MY | 1 |
| Hattori, T; Iwase, E; Miyachi, M; Murase, T; Murohara, T; Nagata, K; Ohtake, M; Takahashi, K; Tsuboi, K | 1 |
| López-Rubalcava, C; Oikawa, J; Paez-Martinez, N | 1 |
| Agorastos, A; Demiralay, C; Steiger, A; Wiedemann, K | 1 |
| Clark, JK; Hammond, S; Keralapurath, MM; Wagner, JJ | 1 |
| Bitencourt, RM; Pamplona, FA; Takahashi, RN | 1 |
| Achterberg, EJ; Trezza, V; Vanderschuren, LJ | 1 |
| Almada, RC; Brandão, ML; Fogaça, MV; Reis, FM | 1 |
| Kalamarz-Kubiak, H; Kleszczyńska, A; Kulczykowska, E | 1 |
| Laorden, ML; Milanés, MV; Navarro-Zaragoza, J | 1 |
| Aono, H; Choudhury, ME; Fujita, T; Islam, A; Mise, A; Miyanishi, K; Nishioka, R; Sugimoto, K; Takahashi, H; Takeda, H; Tanaka, J; Yano, H | 1 |
| Aiso, S; Hiraoka, Y; Nogami, H | 1 |
| Chapman, KE; Hadoke, PW; MacRae, VE; Rashdan, NA; Zhu, D | 1 |
| Davies, DR; Forster, GL; Fox, LC; Scholl, JL; Watt, MJ | 1 |
| Aoun, P; Roelfsema, F; Veldhuis, JD | 1 |
| Aedo, JE; Espinoza, MB; Molina, A; Valdés, JA; Valenzuela, C; Zuloaga, R | 1 |
| Anderson, BM; Fitzgerald, DP; George, AJ; McNay, EC; O'Leary, KE; Osborne, DM; Vidal, MM | 1 |
| Costa, G; Morelli, M; Paci, E; Serra, M; Simola, N | 1 |
| Di, W; Ding, G; Huang, M; Liu, J; Lv, S; Lv, Y; Qi, H; Sheng, Y; Yu, J; Zhou, S | 1 |
| Badmus, OO; Olatunji, LA | 1 |
| Bailey, MA; Costello, HM; Flatman, PW; Ivy, JR; Jones, NK; Mansley, MK; Peltz, TS | 1 |
| de Azevedo Camin, N; de Barcellos Filho, PCG; Franci, CR; Traslaviña, GAA | 1 |
| Pfalzgraff, T; Skov, PV | 1 |
| Kashefi, A; Nasrollahi, N; Raise-Abdullahi, P; Rashidy-Pour, A; Vafaei, AA | 1 |
| Barkovskaya, ES; Bolshakov, AP; Gulyaeva, NV; Kvichansky, AA; Manolova, AO; Tret'yakova, LV | 1 |
1 review(s) available for spironolactone and mifepristone
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
7 trial(s) available for spironolactone and mifepristone
| Article | Year |
|---|---|
Sleep endocrine effects of antigluco- and antimineralocorticoids in healthy males.
Topics: Adrenocorticotropic Hormone; Adult; Dexamethasone; Electroencephalography; Endocrine Glands; Glucocorticoids; Humans; Hydrocortisone; Male; Mifepristone; Mineralocorticoids; Reference Values; Sleep; Spironolactone | 1994 |
Type II (glucocorticoid) receptors mediate fast-feedback inhibition of the hypothalamic-pituitary-adrenal axis in man.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Adult; Feedback; Humans; Hydrocortisone; Hypothalamus; Male; Mifepristone; Pituitary Gland; Receptors, Glucocorticoid; Spironolactone | 1996 |
A regulatory role of prolactin, growth hormone, and corticosteroids for human T-cell production of cytokines.
Topics: Adrenal Cortex Hormones; Adult; Cells, Cultured; Circadian Rhythm; Cytokines; Flow Cytometry; Hormone Antagonists; Human Growth Hormone; Humans; Hydrocortisone; Interferon-gamma; Interleukin-1; Interleukin-2; Male; Mifepristone; Prolactin; Receptors, Steroid; Reference Values; Sleep; Spironolactone; T-Lymphocyte Subsets; Th1 Cells; Th2 Cells; Tumor Necrosis Factor-alpha | 2004 |
Combined receptor antagonist stimulation of the hypothalamic-pituitary-adrenal axis test identifies impaired negative feedback sensitivity to cortisol in obese men.
Topics: Adult; Blood Pressure; Cross-Over Studies; Double-Blind Method; Feedback; Female; Hormone Antagonists; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Male; Middle Aged; Mifepristone; Mineralocorticoid Receptor Antagonists; Obesity; Overweight; Pituitary-Adrenal System; Placebos; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone; Waist-Hip Ratio | 2009 |
Blocking mineralocorticoid receptors impairs, blocking glucocorticoid receptors enhances memory retrieval in humans.
Topics: Adolescent; Adult; Double-Blind Method; Hormone Antagonists; Humans; Male; Mental Recall; Mifepristone; Mineralocorticoid Receptor Antagonists; Neuropsychological Tests; Photic Stimulation; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Sleep; Spironolactone; Time Factors; Young Adult | 2013 |
Sleep EEG effects of anti-gluco- and anti-mineralocorticoids in old-aged men: pilot study.
Topics: Aged; Aged, 80 and over; Aging; Electroencephalography; Humans; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Pilot Projects; Receptors, Glucocorticoid; Single-Blind Method; Sleep Stages; Spironolactone | 2014 |
Pulsatile Cortisol Feedback on ACTH Secretion Is Mediated by the Glucocorticoid Receptor and Modulated by Gender.
Topics: Adrenocorticotropic Hormone; Adult; Double-Blind Method; Eplerenone; Female; Hormone Antagonists; Humans; Hydrocortisone; Male; Middle Aged; Mifepristone; Mineralocorticoid Receptor Antagonists; Prospective Studies; Receptors, Glucocorticoid; Sex Factors; Spironolactone | 2016 |
165 other study(ies) available for spironolactone and mifepristone
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
The lecanindoles, nonsteroidal progestins from the terrestrial fungus Verticillium lecanii 6144.
Topics: Animals; Chlorocebus aethiops; Female; Humans; Hypocreales; Indoles; Luciferases; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Progestins; Receptors, Progesterone; Sesquiterpenes | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
[The age-related characteristics of the hormonal regulation of Na+, K(+)-ATPase activity in the kidney cortex of rats].
Topics: Adrenalectomy; Aging; Aldosterone; Animals; Kidney Cortex; Kidney Tubules, Collecting; Kidney Tubules, Distal; Male; Mifepristone; Rats; Rats, Wistar; Receptors, Mineralocorticoid; Sodium-Potassium-Exchanging ATPase; Spironolactone | 1992 |
Dexamethasone and aldosterone modulate corticotropin-releasing factor-41 release from cultured rat fetal hypothalamic cells through type II and type I corticosteroid receptors respectively.
Topics: Aldosterone; Animals; Cells, Cultured; Colforsin; Corticotropin-Releasing Hormone; Dexamethasone; Fetus; Hypothalamus; Mifepristone; Mineralocorticoid Receptor Antagonists; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Spironolactone | 1992 |
Glucocorticoid regulation of atrial natriuretic peptide receptors on cultured endothelial cells.
Topics: Animals; Atrial Natriuretic Factor; Autoradiography; Binding, Competitive; Cells, Cultured; Cross-Linking Reagents; Cyclic GMP; Dexamethasone; Endothelium, Vascular; Glucocorticoids; Mifepristone; Peptide Fragments; Receptors, Atrial Natriuretic Factor; Receptors, Cell Surface; Spironolactone | 1991 |
Apparent mineralocorticoid excess, pseudohypoaldosteronism, and urinary electrolyte excretion: toward a redefinition of mineralocorticoid action.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adrenalectomy; Aldosterone; Androstanols; Animals; Bicarbonates; Carbenoxolone; Child; Electrolytes; Female; Humans; Hydrocortisone; Hydroxysteroid Dehydrogenases; Male; Mifepristone; Mineralocorticoids; Natriuresis; Pseudohypoaldosteronism; Rats; Rats, Inbred Strains; Receptors, Mineralocorticoid; Receptors, Steroid; Spironolactone | 1990 |
Differential central effects of mineralocorticoid and glucocorticoid agonists and antagonists on blood pressure.
Topics: Adrenalectomy; Aldosterone; Androstanols; Animals; Blood Pressure; Brain; Corticosterone; Glucocorticoids; Injections, Intraventricular; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Mineralocorticoids; Rats; Rats, Inbred Strains; Spironolactone | 1990 |
On the role of brain mineralocorticoid (type I) and glucocorticoid (type II) receptors in neuroendocrine regulation.
Topics: Animals; Brain; Corticosterone; Estrenes; Glucocorticoids; Injections, Intraventricular; Injections, Subcutaneous; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Rats; Rats, Inbred Strains; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Receptors, Steroid; Spironolactone; Stress, Physiological | 1989 |
Mineralocorticoid-induced increase in beta-adrenergic receptors of cultured rat arterial smooth muscle cells.
Topics: Aldosterone; Animals; Cells, Cultured; Cyclic AMP; Cycloheximide; Dihydroalprenolol; Mifepristone; Muscle, Smooth, Vascular; Rats; Receptors, Adrenergic, beta; Spironolactone | 1989 |
High affinity binding and regulatory actions of dexamethasone-type I receptor complexes in mouse brain.
Topics: Aldosterone; Animals; Brain; Cytosol; Dexamethasone; DNA-Binding Proteins; Estrenes; Female; Glucocorticoids; Kinetics; Mice; Mifepristone; Organ Specificity; Receptors, Glucocorticoid; Spironolactone | 1989 |
Adrenocorticotropin and cortisol-induced changes in urinary sodium and potassium excretion in man: effects of spironolactone and RU486.
Topics: Adrenocorticotropic Hormone; Adult; Blood Glucose; Chlorides; Estrenes; Humans; Hydrocortisone; Insulin; Male; Mifepristone; Natriuresis; Potassium; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Receptors, Steroid; Spironolactone | 1988 |
Corticosterone's metabolite is an agonist for Na+ transport stimulation in A6 cells.
Topics: Animals; Biological Transport, Active; Cell Line; Cell Membrane; Cell Nucleus; Computer Simulation; Corticosterone; Estrenes; Glucocorticoids; Kinetics; Membrane Potentials; Mifepristone; Models, Biological; Receptors, Glucocorticoid; Receptors, Steroid; Sodium; Spironolactone | 1988 |
Corticosteroid regulation of Na+ and K+ transport in the rat distal colon during postnatal development.
Topics: Adrenal Cortex Hormones; Adrenalectomy; Aging; Aldosterone; Amiloride; Animals; Animals, Suckling; Colon; Corticosterone; Dexamethasone; Estrenes; Mifepristone; Potassium; Rats; Sodium; Spironolactone | 1988 |
Antiglucocorticoid RU 38486 attenuates retention of a behaviour and disinhibits the hypothalamic-pituitary adrenal axis at different brain sites.
Topics: Adrenalectomy; Animals; Behavior, Animal; Brain; Corticosterone; Dexamethasone; Dose-Response Relationship, Drug; Estrenes; Hypothalamo-Hypophyseal System; Injections, Intraventricular; Male; Memory; Mifepristone; Pituitary-Adrenal System; Rats; Rats, Inbred Strains; Receptors, Glucocorticoid; Retention, Psychology; Spironolactone | 1988 |
[Effect of an antiglucocorticoid steroid on the arterial hypertension induced by glucocorticoids in the rat].
Topics: Androstanols; Animals; Blood Pressure; Estrenes; Glucocorticoids; Hypertension; Male; Mifepristone; Mineralocorticoids; Rats; Rats, Inbred Strains; Sodium; Spironolactone | 1984 |
Opposing roles of type I and type II adrenal steroid receptors in hippocampal long-term potentiation.
Topics: Adrenal Cortex Hormones; Adrenalectomy; Aldosterone; Animals; Corticosterone; Dentate Gyrus; Electric Stimulation; Hippocampus; Hormone Antagonists; Long-Term Potentiation; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Neural Pathways; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Steroid; Spironolactone | 1995 |
Determinants of cardiac fibrosis in experimental hypermineralocorticoid states.
Topics: Adrenalectomy; Aldosterone; Animals; Desoxycorticosterone; Drug Combinations; Fibrosis; Fludrocortisone; Heart; Hormone Antagonists; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Myocardium; Nephrectomy; Potassium; Rats; Rats, Sprague-Dawley; Spironolactone | 1995 |
Cardiovascular effects of microinjection of corticoids and antagonists into the rostral ventrolateral medulla in rats.
Topics: Aldosterone; Animals; Blood Pressure; Cardiovascular System; Corticosterone; Female; Glucocorticoids; Heart Rate; Male; Medulla Oblongata; Microinjections; Mifepristone; Mineralocorticoids; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Rats, Wistar; Spironolactone | 1995 |
Further studies in deoxycorticosterone acetate treated rats: brain content of mineralocorticoid and glucocorticoid receptors and effect of steroid antagonists on salt intake.
Topics: Amygdala; Animals; Appetite; Brain; Desoxycorticosterone; Hippocampus; Hypothalamus; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Ornithine Decarboxylase; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Sodium Chloride, Dietary; Spironolactone | 1995 |
Consequence of long-term exposure to corticosterone or dexamethasone on ethanol consumption in the adrenalectomized rat, and the effect of type I and type II corticosteroid receptor antagonists.
Topics: Adrenalectomy; Alcohol Drinking; Animals; Body Weight; Corticosterone; Dexamethasone; Drinking; Drug Implants; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Organ Size; Rats; Rats, Wistar; Receptors, Steroid; Sodium Chloride; Spironolactone | 1995 |
The effects of RU 38486 and RU 28318 on energy balance of ovariectomized rats.
Topics: Analysis of Variance; Animals; Energy Metabolism; Female; Mifepristone; Mineralocorticoid Receptor Antagonists; Ovariectomy; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Reference Values; Spironolactone | 1994 |
The effect of corticosterone on reactivity to spatial novelty is mediated by central mineralocorticosteroid receptors.
Topics: Adrenalectomy; Adrenocorticotropic Hormone; Animals; Corticosterone; Exploratory Behavior; Locomotion; Male; Mifepristone; Rats; Rats, Wistar; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spatial Behavior; Spironolactone | 1994 |
Corticosteroid receptor antagonists are amnestic for passive avoidance learning in day-old chicks.
Topics: Amnesia; Animals; Animals, Newborn; Avoidance Learning; Brain; Chickens; Female; Injections; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Neuronal Plasticity; Receptors, Glucocorticoid; Receptors, Steroid; Spironolactone | 1994 |
Development of specific bioluminescent in vitro assays for selecting potential antimineralocorticoids.
Topics: Animals; Base Sequence; Biological Assay; Cell Line; Dexamethasone; HeLa Cells; Hormone Antagonists; Humans; Luciferases; Luminescent Measurements; Mifepristone; Mineralocorticoid Receptor Antagonists; Mineralocorticoids; Molecular Sequence Data; Pregnenediones; Promegestone; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Receptors, Progesterone; Recombinant Fusion Proteins; Spironolactone; Testosterone; Transfection | 1994 |
Sound stress activation of tryptophan hydroxylase blocked by hypophysectomy and intracranial RU 38486.
Topics: Acoustic Stimulation; Animals; Cerebral Cortex; Dexamethasone; Enzyme Activation; Hypophysectomy; Hypothalamo-Hypophyseal System; Injections, Intraventricular; Male; Mesencephalon; Mifepristone; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Spironolactone; Stress, Psychological; Tryptophan Hydroxylase | 1994 |
Regulation of sodium-potassium adenosine triphosphate subunit gene expression by corticosteroids and 11 beta-hydroxysteroid dehydrogenase activity.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adrenal Cortex Hormones; Animals; Gene Expression Regulation; Glycyrrhetinic Acid; Glycyrrhizic Acid; Hydroxysteroid Dehydrogenases; Kidney; Male; Mifepristone; Rats; Rats, Wistar; RNA, Messenger; Sodium-Potassium-Exchanging ATPase; Spironolactone | 1994 |
Direct and indirect effects of carbenoxolone on responses to glucocorticoids and noradrenaline in rat aorta.
Topics: Adrenalectomy; Animals; Aorta; Carbenoxolone; Corticosterone; Glucocorticoids; In Vitro Techniques; Male; Mifepristone; Norepinephrine; Rats; Rats, Wistar; Spironolactone; Vasoconstriction | 1994 |
Type II corticosteroid receptor stimulation increases NPY gene expression in basomedial hypothalamus of rats.
Topics: Adrenalectomy; Aldosterone; Androstanols; Animals; Blood Glucose; Drug Interactions; Gene Expression Regulation; Hypothalamus, Middle; Infusions, Parenteral; Insulin; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Neuropeptide Y; Rats; Rats, Sprague-Dawley; Receptors, Steroid; RNA, Messenger; Spironolactone | 1994 |
Role of glucocorticoids in the regulation of brain prostaglandin biosynthesis under basal conditions and in response to endotoxin.
Topics: Adrenalectomy; Animals; Cerebral Cortex; Cerebral Ventricles; Dexamethasone; Dinoprostone; In Vitro Techniques; Injections, Intraventricular; Lipopolysaccharides; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Rats; Rats, Inbred Strains; Reference Values; Spironolactone | 1993 |
Anxiolytic-like effects of selective mineralocorticoid and glucocorticoid antagonists on fear-enhanced behavior in the elevated plus-maze.
Topics: Animals; Anxiety; Behavior, Animal; Fear; Injections, Intraventricular; Male; Maze Learning; Mifepristone; Mineralocorticoid Receptor Antagonists; Rats; Rats, Wistar; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone; Stress, Physiological | 1995 |
Differential regulation of Na+-K+-ATPase gene expression by corticosteriods in vascular smooth muscle cells.
Topics: Adrenal Cortex Hormones; Aldosterone; Amiloride; Analysis of Variance; Animals; Aorta, Thoracic; Cells, Cultured; Dexamethasone; Gene Expression Regulation, Enzymologic; Kinetics; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase; Spironolactone | 1996 |
A role for the mineralocorticoid receptor in a rapid and transient suppression of hippocampal 5-HT1A receptor mRNA by corticosterone.
Topics: Adrenalectomy; Animals; Corticosterone; Densitometry; Dose-Response Relationship, Drug; Gene Expression Regulation; Hippocampus; In Situ Hybridization; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Rats; Rats, Wistar; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Receptors, Serotonin; RNA, Messenger; Spironolactone | 1995 |
Mineralocorticoid and glucocorticoid receptor antagonists in animal models of anxiety.
Topics: Acoustic Stimulation; Animals; Anxiety; Behavior, Animal; Electroshock; Fear; Hormone Antagonists; Injections, Intraventricular; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Motor Activity; Rats; Rats, Wistar; Receptors, Glucocorticoid; Reflex, Startle; Spironolactone | 1996 |
Involvement of type I corticosteroid receptor in the effects of ovariectomy on energy balance.
Topics: Animals; Body Weight; Energy Metabolism; Female; Lipid Metabolism; Mifepristone; Mineralocorticoid Receptor Antagonists; Ovariectomy; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone | 1996 |
Facilitation of ethanol consumption by intracerebroventricular infusions of corticosterone.
Topics: Adrenalectomy; Alcohol Drinking; Animals; Corticosterone; Drinking; Injections, Intraventricular; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Rats; Rats, Wistar; Receptors, Glucocorticoid; Spironolactone | 1996 |
Effects of corticosteroids on parameters related to Na+ transport by amphibian renal distal cells (A6) in culture.
Topics: Adrenal Cortex Hormones; Aldosterone; Animals; Biological Transport; Cell Line; Corticosterone; Dexamethasone; Electrophysiology; Epithelium; Glucocorticoids; Hormone Antagonists; Kidney Tubules, Distal; Mifepristone; Mineralocorticoid Receptor Antagonists; Ouabain; Receptors, Glucocorticoid; Sodium; Sodium-Potassium-Exchanging ATPase; Spironolactone; Xenopus laevis | 1996 |
Hippocampal mineralocorticoid, but not glucocorticoid, receptors modulate anxiety-like behavior in rats.
Topics: Analysis of Variance; Animals; Anxiety; Drug Evaluation, Preclinical; Hippocampus; Male; Microinjections; Mifepristone; Mineralocorticoid Receptor Antagonists; Motor Activity; Rats; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone | 1997 |
Effect of glucocorticoids on the adrenocortical axis responses to electrical stimulation of the amygdala and the ventral noradrenergic bundle.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Amygdala; Animals; Corticosterone; Corticotropin-Releasing Hormone; Dexamethasone; Electric Stimulation; Feedback; Hypothalamo-Hypophyseal System; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Pituitary-Adrenal System; Rats; Rats, Inbred Strains; Spironolactone | 1997 |
Cell-specific, promoter-dependent mineralocorticoid agonist activity of spironolactone.
Topics: Aldosterone; Carcinoma, Hepatocellular; Dose-Response Relationship, Drug; Humans; Mifepristone; Promoter Regions, Genetic; Spironolactone; Tumor Cells, Cultured | 1997 |
Role of adrenal steroids in stimulating ammonium excretion during acute metabolic acidosis.
Topics: Acidosis; Adrenal Cortex Hormones; Adrenal Glands; Ammonium Chloride; Animals; Corticosterone; Hormone Antagonists; Hydrogen-Ion Concentration; Hydroxysteroid Dehydrogenases; Kidney Tubules, Collecting; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley; Spironolactone; Steroids | 1997 |
Facilitation of feedback inhibition through blockade of glucocorticoid receptors in the hippocampus.
Topics: Adrenocorticotropic Hormone; Animals; Circadian Rhythm; Corticosterone; Feedback; Hippocampus; Hypothalamus; Injections, Intraventricular; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Pituitary-Adrenal System; Rats; Rats, Wistar; Receptors, Glucocorticoid; Spironolactone | 1997 |
A role for brain glucocorticoid receptors in contextual fear conditioning: dependence upon training intensity.
Topics: Animals; Brain; Conditioning, Psychological; Corticosterone; Electroshock; Fear; Hormone Antagonists; Injections, Intraventricular; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Rats; Rats, Wistar; Receptors, Glucocorticoid; Spironolactone | 1998 |
Regulation of hippocampal theta activity by corticosterone: opposing functions of mineralocorticoid and glucocorticoid receptors.
Topics: Analysis of Variance; Animals; Corticosterone; Electric Stimulation; Hippocampus; Hypothalamus, Posterior; Male; Mifepristone; Rats; Rats, Inbred Strains; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone; Theta Rhythm; Time Factors | 1998 |
Involvement of glucocorticoids in the reorganization of the amphibian immune system at metamorphosis.
Topics: Aldosterone; Animals; Apoptosis; Corticosterone; Glucocorticoids; Hormone Antagonists; Lymphocyte Activation; Lymphocytes; Metamorphosis, Biological; Mifepristone; Spironolactone; Spleen; Thymus Gland; Xenopus laevis | 1997 |
Localization of Na,K-ATPase activity in developing rat distal colon: role of corticosteroids.
Topics: 4-Nitrophenylphosphatase; Adrenal Cortex Hormones; Adrenalectomy; Aging; Aldosterone; Animals; Colon; Desoxycorticosterone; Dexamethasone; Glucocorticoids; Hormone Antagonists; Intestinal Mucosa; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Ouabain; Rats; Rats, Wistar; Receptors, Glucocorticoid; Sodium-Potassium-Exchanging ATPase; Spironolactone | 1998 |
Evidence for mineralocorticoid receptor facilitation of glucocorticoid receptor-dependent regulation of hypothalamic-pituitary-adrenal axis activity.
Topics: Adrenocorticotropic Hormone; Animals; Circadian Rhythm; Corticosterone; Drug Combinations; Hormone Antagonists; Hypothalamo-Hypophyseal System; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Pituitary-Adrenal System; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Receptors, Steroid; Spironolactone | 1998 |
Repeated blockade of mineralocorticoid receptors, but not of glucocorticoid receptors impairs food rewarded spatial learning.
Topics: Animals; Corticosterone; Food; Hippocampus; Hormone Antagonists; Male; Maze Learning; Mifepristone; Mineralocorticoid Receptor Antagonists; Rats; Rats, Wistar; Receptors, Glucocorticoid; Reward; Space Perception; Spironolactone | 1998 |
Dopamine-dependent responses to morphine depend on glucocorticoid receptors.
Topics: Animals; Dopamine; Hormone Antagonists; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Morphine; Motor Activity; Narcotics; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone | 1998 |
Corticosterone and 11-dehydrocorticosterone stimulate Na,K-ATPase gene expression in vascular smooth muscle cells.
Topics: Animals; Aorta; Cells, Cultured; Corticosterone; Dactinomycin; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Male; Mifepristone; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium-Potassium-Exchanging ATPase; Spironolactone | 1998 |
Corticosterone is permissive to the anxiolytic effect that results from the blockade of hippocampal mineralocorticoid receptors.
Topics: Adrenalectomy; Animals; Anti-Anxiety Agents; Anti-Inflammatory Agents; Anxiety; Corticosterone; Cortisone; Dexamethasone; Hippocampus; Male; Microinjections; Mifepristone; Mineralocorticoid Receptor Antagonists; Rats; Receptors, Glucocorticoid; Spironolactone | 1998 |
Piracetam facilitates long-term memory for a passive avoidance task in chicks through a mechanism that requires a brain corticosteroid action.
Topics: Adrenal Cortex Hormones; Animals; Animals, Newborn; Avoidance Learning; Brain; Chickens; Corticosterone; Female; Hormone Antagonists; Male; Memory; Mifepristone; Mineralocorticoid Receptor Antagonists; Nootropic Agents; Piracetam; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone | 1998 |
Evaluation of RU28318 and RU40555 as selective mineralocorticoid receptor and glucocorticoid receptor antagonists, respectively: receptor measures and functional studies.
Topics: Adrenalectomy; Animals; Biological Assay; Corticosterone; Dexamethasone; Hippocampus; Hormone Antagonists; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Pituitary Gland; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone | 1998 |
Adrenocorticotrophin-induced hypertension: effects of mineralocorticoid and glucocorticoid receptor antagonism.
Topics: Adrenocorticotropic Hormone; Animals; Anti-Bacterial Agents; Blood Pressure; Disease Models, Animal; Drug Therapy, Combination; Hypertension; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Potassium; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Sodium; Spironolactone; Troleandomycin | 1999 |
Lesion-induced plasticity in rat vestibular nucleus neurones dependent on glucocorticoid receptor activation.
Topics: Anesthesia; Animals; Behavior, Animal; Denervation; Dexamethasone; Ear, Inner; Glucocorticoids; Immunohistochemistry; In Vitro Techniques; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Neuronal Plasticity; Neurons; Paraventricular Hypothalamic Nucleus; Proto-Oncogene Proteins c-fos; Rats; Receptors, Glucocorticoid; Spironolactone; Stress, Psychological; Vestibular Nuclei | 1999 |
Corticosterone modifies muscarinic receptor immunoreactivity in rat hippocampus.
Topics: Acetylcholine; Adrenalectomy; Animals; Corticosterone; Hippocampus; Immunohistochemistry; Male; Mifepristone; Rats; Rats, Wistar; Receptors, Muscarinic; Spironolactone | 1999 |
Aldosterone activates Na+/H+ exchange in vascular smooth muscle cells by nongenomic and genomic mechanisms.
Topics: Aldosterone; Animals; Aorta, Thoracic; Cells, Cultured; Cycloheximide; Cytoskeleton; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Activation; Gene Expression; Hormone Antagonists; Hydrogen-Ion Concentration; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Muscle, Smooth, Vascular; Protein Kinase C; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Sodium-Hydrogen Exchangers; Spironolactone; Transcription, Genetic | 1999 |
Effects of glucocorticoids and mineralocorticoids on proliferation and maturation of human peripheral blood stem cells.
Topics: Adult; Aldosterone; Cells, Cultured; Colony-Forming Units Assay; Desoxycorticosterone; Erythropoietin; Glucocorticoids; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cells; Humans; Interleukin-3; Mifepristone; Mineralocorticoids; Recombinant Proteins; Spironolactone; Triamcinolone Acetonide | 1999 |
Regulation of cyclooxygenase-2 (COX-2) in rat renal cortex by adrenal glucocorticoids and mineralocorticoids.
Topics: Adrenalectomy; Animals; Cyclooxygenase 2; Gene Expression Regulation, Enzymologic; Glucocorticoids; Isoenzymes; Kidney Cortex; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Mineralocorticoids; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Spironolactone | 1999 |
The amygdala: site of genomic and nongenomic arousal of aldosterone-induced sodium intake.
Topics: Aldosterone; Amygdala; Animals; Appetite; Arousal; Corticosterone; Desoxycorticosterone; Genome; Hormone Antagonists; Injections; Injections, Intraventricular; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Oligonucleotides, Antisense; Rats; Rats, Sprague-Dawley; Receptors, GABA; Receptors, Mineralocorticoid; Sodium; Spironolactone | 2000 |
Glucocorticoid modulates Na+/H+ exchange activity in vascular smooth muscle cells by nongenomic and genomic mechanisms.
Topics: Animals; Cells, Cultured; Corticosterone; Cycloheximide; Cytoskeleton; Dactinomycin; Dose-Response Relationship, Drug; Genome; Hydrogen-Ion Concentration; Intracellular Membranes; Male; Mifepristone; Muscle, Smooth, Vascular; Nucleic Acid Synthesis Inhibitors; Protein Kinase C; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Steroid; RNA, Messenger; Sodium-Hydrogen Exchangers; Spironolactone | 2000 |
Glucocorticoid modulation of dopamine mediated effects on hypothalamic atrial natriuretic factor neurons.
Topics: Animals; Animals, Newborn; Atrial Natriuretic Factor; Cells, Cultured; Desoxycorticosterone; Dexamethasone; Dopamine; Down-Regulation; Gene Expression Regulation; Glucocorticoids; Hypothalamus; Mifepristone; Neurons; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Spironolactone; Transcription, Genetic | 2000 |
The mineralocorticoid receptor mediates aldosterone-induced differentiation of T37i cells into brown adipocytes.
Topics: Adipose Tissue, Brown; Aldosterone; Animals; Carrier Proteins; Cell Differentiation; Dose-Response Relationship, Drug; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Hormone Antagonists; Lipoma; Lipoprotein Lipase; Mice; Mifepristone; Mineralocorticoid Receptor Antagonists; Myelin P2 Protein; Neoplasm Proteins; Nerve Tissue Proteins; Receptors, Cytoplasmic and Nuclear; Receptors, Mineralocorticoid; RNA, Messenger; Spironolactone; Transcription Factors; Transcription, Genetic; Triglycerides; Tumor Cells, Cultured | 2000 |
Selective blockade of the mineralocorticoid receptor impairs hypothalamic-pituitary-adrenal axis expression of habituation.
Topics: Animals; Corticosterone; Drug Combinations; Habituation, Psychophysiologic; Hormone Antagonists; Hypothalamo-Hypophyseal System; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Pituitary-Adrenal System; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Restraint, Physical; Spironolactone; Stress, Physiological | 2000 |
Endogenous glucocorticoids play a positive regulatory role in the anti-keyhole limpet hemocyanin in vivo antibody response.
Topics: Administration, Oral; Adrenalectomy; Animals; Antigens; Corticosterone; Dexamethasone; Drug Combinations; Hemocyanins; Hormone Antagonists; Hypertrophy; Immunoglobulin G; Immunoglobulin Isotypes; Immunoglobulin M; Immunosuppressive Agents; Injections, Intraperitoneal; Injections, Subcutaneous; Interferon-gamma; Male; Mifepristone; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Spironolactone; Spleen; Thymus Gland | 2001 |
Adrenocorticosteroid receptor blockade and excitotoxic challenge regulate adrenocorticosteroid receptor mRNA levels in hippocampus.
Topics: Animals; Cell Count; Corticosterone; Excitatory Amino Acid Agonists; Hippocampus; Hormone Antagonists; Kainic Acid; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Pyramidal Cells; Rats; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; RNA, Messenger; Spironolactone | 2001 |
Glucocorticoid and mineralocorticoid receptors are involved in the facilitation of anxiety-like response induced by restraint.
Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents; Anxiety; Corticosterone; Dexamethasone; Injections, Intraventricular; Male; Metyrapone; Mifepristone; Mineralocorticoid Receptor Antagonists; Rats; Rats, Wistar; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Restraint, Physical; Spironolactone; Stress, Psychological | 2001 |
Intracerebroventricular administration of a glucocorticoid receptor antagonist enhances the cardiovascular responses to brief restraint stress.
Topics: Animals; Blood Pressure; Circadian Rhythm; Heart Rate; Hot Temperature; Injections, Intraventricular; Male; Mifepristone; Rats; Rats, Wistar; Receptors, Glucocorticoid; Restraint, Physical; Spironolactone; Stress, Physiological; Time Factors | 2001 |
Mifepristone protects CA1 hippocampal neurons following traumatic brain injury in rat.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Brain Injuries; Cell Survival; Glucocorticoids; Hippocampus; Hormone Antagonists; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Mineralocorticoids; Neurons; Neuroprotective Agents; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; RNA, Messenger; Spironolactone; Tumor Suppressor Protein p53 | 2002 |
Evidence for a mineralocorticoid-like receptor linked to branchial chloride cell proliferation in freshwater rainbow trout.
Topics: Adaptation, Physiological; Adrenal Cortex Hormones; Animals; Cell Division; Chlorides; Fresh Water; Gills; Hydrocortisone; Kidney; Mifepristone; Oncorhynchus mykiss; Receptors, Mineralocorticoid; Sodium-Potassium-Exchanging ATPase; Spironolactone | 2001 |
Traumatic brain injury regulates adrenocorticosteroid receptor mRNA levels in rat hippocampus.
Topics: Adrenocorticotropic Hormone; Animals; Brain Injuries; Corticosterone; Hippocampus; Hormone Antagonists; In Situ Hybridization; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; RNA, Messenger; Spironolactone | 2002 |
Rapid non-genomic inhibition of ATP-induced Cl- secretion by dexamethasone in human bronchial epithelium.
Topics: Adenosine Triphosphate; Bronchi; Calcium; Cell Line; Chlorides; Cycloheximide; Dexamethasone; Epithelium; Glucocorticoids; Hormone Antagonists; Humans; Intracellular Membranes; Mifepristone; Mineralocorticoid Receptor Antagonists; Osmolar Concentration; Protein Synthesis Inhibitors; Signal Transduction; Spironolactone; Time Factors | 2002 |
Serum- and glucocorticoid-regulated kinase isoform-1 and epithelial sodium channel subunits in human ocular ciliary epithelium.
Topics: Aldosterone; Blotting, Northern; Cell Line; Ciliary Body; Dexamethasone; Dose-Response Relationship, Drug; Drug Combinations; Epithelial Sodium Channels; Gene Expression Regulation; Glucocorticoids; Hormone Antagonists; Humans; Immediate-Early Proteins; In Situ Hybridization; Isoenzymes; Mifepristone; Mineralocorticoid Receptor Antagonists; Nuclear Proteins; Pigment Epithelium of Eye; Protein Serine-Threonine Kinases; Receptors, Glucocorticoid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium Channels; Spironolactone | 2003 |
Stimulation of protein degradation by low pH in L6G8C5 skeletal muscle cells is independent of apoptosis but dependent on differentiation state.
Topics: Acidosis; Animals; Apoptosis; Cell Differentiation; Cells, Cultured; Creatine Kinase; Culture Media, Serum-Free; Cysteine Proteinase Inhibitors; Hormone Antagonists; Hydrogen-Ion Concentration; In Vitro Techniques; Leupeptins; Mifepristone; Muscle, Skeletal; Rats; Receptors, Glucocorticoid; Spironolactone | 2003 |
Early aldosterone up-regulated genes: new pathways for renal disease?
Topics: Aldosterone; Blotting, Northern; Blotting, Western; CCAAT-Enhancer-Binding Proteins; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; GADD45 Proteins; Gene Expression Profiling; Hormone Antagonists; Humans; Immediate-Early Proteins; Intracellular Signaling Peptides and Proteins; Kidney Diseases; Mifepristone; Nuclear Proteins; Oligonucleotide Array Sequence Analysis; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spironolactone; Transcription Factor CHOP; Transcription Factors; Up-Regulation | 2003 |
Aldosterone stimulates gene expression of hepatic gluconeogenic enzymes through the glucocorticoid receptor in a manner independent of the protein kinase B cascade.
Topics: Aldosterone; Animals; Blood Glucose; Carboxy-Lyases; Cells, Cultured; Female; Fructose-Bisphosphatase; Gene Expression; Gene Expression Regulation; Gluconeogenesis; Glucose-6-Phosphatase; Hepatocytes; Humans; Insulin; Liver; Mice; Mice, Inbred ICR; Mifepristone; Mineralocorticoid Receptor Antagonists; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, Glucocorticoid; Signal Transduction; Spironolactone | 2004 |
The glucocorticoid receptor antagonist mifepristone reduces ethanol intake in rats under limited access conditions.
Topics: Alcohol Drinking; Animals; Choice Behavior; Dose-Response Relationship, Drug; Drinking; Drinking Behavior; Ethanol; Hormone Antagonists; Male; Mifepristone; Rats; Rats, Long-Evans; Receptors, Glucocorticoid; Spironolactone | 2004 |
Glucocorticoid receptors are involved in the regulation of pulsatile urea excretion in toadfish.
Topics: Analysis of Variance; Animals; Batrachoidiformes; Biological Transport; Florida; Gills; Hydrocortisone; Mifepristone; Peanut Oil; Plant Oils; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone; Urea | 2004 |
Aldosterone directly stimulates cardiac myocyte hypertrophy.
Topics: Aldosterone; Animals; Animals, Newborn; Cells, Cultured; Culture Media, Serum-Free; Dexamethasone; Extracellular Signal-Regulated MAP Kinases; Glucocorticoids; Hormone Antagonists; Hypertrophy; JNK Mitogen-Activated Protein Kinases; Microscopy, Confocal; Mifepristone; Mineralocorticoid Receptor Antagonists; Mitogen-Activated Protein Kinases; Myocytes, Cardiac; Protein Kinase C; Rats; Rats, Wistar; Receptors, Mineralocorticoid; Spironolactone | 2004 |
Blockage of glucocorticoid, but not mineralocorticoid receptors prevents the persistent increase in circulating basal corticosterone concentrations following stress in the rat.
Topics: Adaptation, Physiological; Animals; Circadian Rhythm; Corticosterone; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone; Stress, Physiological | 2005 |
Corticosterone increases damage and cytosolic calcium accumulation associated with ethanol withdrawal in rat hippocampal slice cultures.
Topics: Animals; Calcium; Central Nervous System Depressants; Corticosterone; Cytosol; Ethanol; Female; Fluorescent Dyes; Hippocampus; Hormone Antagonists; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Organ Culture Techniques; Organic Chemicals; Propidium; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, N-Methyl-D-Aspartate; Spironolactone; Substance Withdrawal Syndrome | 2005 |
Aldosterone increases T-type calcium channel expression and in vitro beating frequency in neonatal rat cardiomyocytes.
Topics: Aldosterone; Animals; Animals, Newborn; Calcium Channels, L-Type; Calcium Channels, T-Type; Corticosterone; Glucocorticoids; Heart Ventricles; Mifepristone; Mineralocorticoid Receptor Antagonists; Myocardial Contraction; Myocytes, Cardiac; Patch-Clamp Techniques; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Spironolactone; Stimulation, Chemical | 2005 |
Glucocorticoid receptor involvement in pair bonding in female prairie voles: the effects of acute blockade and interactions with central dopamine reward systems.
Topics: Animals; Arvicolinae; Dopamine; Female; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Reward; Sexual Behavior, Animal; Social Behavior; Spironolactone | 2005 |
Cultured embryonic hippocampal neurons deficient in glucocorticoid (GC) receptor: a novel model for studying nongenomic effects of GC in the neural system.
Topics: Animals; Cell Culture Techniques; Cell Survival; Corticosterone; Culture Media, Serum-Free; Cycloheximide; Hippocampus; Hormone Antagonists; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mifepristone; Mineralocorticoid Receptor Antagonists; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neurons; p38 Mitogen-Activated Protein Kinases; PC12 Cells; Phosphorylation; Protein Synthesis Inhibitors; Rats; Receptors, Glucocorticoid; RNA, Messenger; Serum Albumin, Bovine; Spironolactone | 2005 |
Effects of spironolactone and RU486 on gene expression and cell proliferation after freshwater transfer in the euryhaline killifish.
Topics: Adaptation, Physiological; Animals; Cell Proliferation; Cystic Fibrosis Transmembrane Conductance Regulator; Fresh Water; Fundulidae; Gene Expression; Gills; Ion Transport; Mifepristone; Mineralocorticoid Receptor Antagonists; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; RNA, Messenger; Seawater; Sodium-Potassium-Chloride Symporters; Sodium-Potassium-Exchanging ATPase; Solute Carrier Family 12, Member 2; Spironolactone | 2005 |
Roles of mineralocorticoid and glucocorticoid receptors in the regulation of progenitor proliferation in the adult hippocampus.
Topics: Adrenalectomy; Analysis of Variance; Animals; Bromodeoxyuridine; Cell Count; Cell Proliferation; Corticosterone; Drug Interactions; Hippocampus; Hormone Antagonists; Immunohistochemistry; Ki-67 Antigen; Male; Mifepristone; Neurons; Organ Size; Rats; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone; Statistics as Topic; Stem Cells; Thymus Gland | 2005 |
Aldosterone increases osteopontin gene expression in rat endothelial cells.
Topics: Aldosterone; Animals; Base Sequence; Cells, Cultured; Cycloheximide; DNA Primers; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Mifepristone; Mineralocorticoid Receptor Antagonists; Osteopontin; Protein Synthesis Inhibitors; Rats; Receptors, Glucocorticoid; RNA, Messenger; Sialoglycoproteins; Spironolactone | 2005 |
Differential action of steroid hormones on human endothelium.
Topics: Aldosterone; Cell Line; Cell Membrane; Cell Polarity; Dexamethasone; Elasticity; Electric Impedance; Endothelial Cells; Glucocorticoids; Hormone Antagonists; Humans; Microscopy, Atomic Force; Mifepristone; Mineralocorticoid Receptor Antagonists; Spironolactone | 2006 |
Maintained ENaC trafficking in aldosterone-infused rats during mineralocorticoid and glucocorticoid receptor blockade.
Topics: Aldosterone; Animals; Drinking; Epithelial Sodium Channels; Hormone Antagonists; Immunoblotting; Immunohistochemistry; Infusions, Intravenous; Kidney Tubules, Collecting; Male; Microscopy, Confocal; Mifepristone; Mineralocorticoid Receptor Antagonists; Potassium; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Sodium-Potassium-Exchanging ATPase; Sodium, Dietary; Spironolactone | 2007 |
Role of glucocorticoid receptor in acclimation of killifish (Fundulus heteroclitus) to seawater and effects of arsenic.
Topics: Acclimatization; Animals; Arsenic; Blotting, Western; Chlorides; Cystic Fibrosis Transmembrane Conductance Regulator; Fundulidae; Gills; Homeostasis; Hormone Antagonists; Hydrocortisone; Mass Spectrometry; Mifepristone; Mineralocorticoid Receptor Antagonists; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Reverse Transcriptase Polymerase Chain Reaction; Seawater; Sodium-Potassium-Chloride Symporters; Sodium-Potassium-Exchanging ATPase; Solute Carrier Family 12, Member 2; Spironolactone; Tissue Distribution | 2007 |
Effects of mineralocorticoid and glucocorticoid receptor blockade on hypothalamic-pituitary-adrenal function in female rats prenatally exposed to ethanol.
Topics: Adrenocorticotropic Hormone; Animals; Body Weight; Central Nervous System Depressants; Ethanol; Feedback; Female; Hormone Antagonists; Hydrocortisone; Hypothalamo-Hypophyseal System; Lactation; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Pituitary-Adrenal System; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Restraint, Physical; Spironolactone; Stress, Psychological | 2006 |
Transactivation of the IGF-1R by aldosterone.
Topics: Aldosterone; Animals; Cell Line; Dactinomycin; Epithelial Cells; Insulin; Insulin Receptor Substrate Proteins; Insulin-Like Growth Factor I; Kidney; Mifepristone; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Proto-Oncogene Proteins c-akt; Receptor, IGF Type 1; Receptor, Insulin; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Signal Transduction; Spironolactone; Transcriptional Activation; Xenopus laevis; Xenopus Proteins | 2007 |
Corticosteroid receptor-mediated mechanisms in the amygdala regulate anxiety and colonic sensitivity.
Topics: Amygdala; Animals; Anxiety; Behavior, Animal; Catheterization; Colon; Drug Implants; Hormone Antagonists; Hydrocortisone; Hyperalgesia; Irritable Bowel Syndrome; Male; Mifepristone; Muscle Contraction; Pressure; Rats; Rats, Inbred F344; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Sensation; Spironolactone | 2007 |
Specific activation of the glucocorticoid receptor and modulation of signal transduction pathways in human lens epithelial cells.
Topics: Apoptosis; Blotting, Western; Cell Cycle Proteins; Cell Proliferation; Dexamethasone; Dual Specificity Phosphatase 1; Epithelial Cells; Flow Cytometry; Humans; Immediate-Early Proteins; Lens, Crystalline; Mifepristone; Mitogen-Activated Protein Kinase Kinases; Phosphatidylinositol 3-Kinases; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 1; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins c-akt; Receptors, Glucocorticoid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Spironolactone; Transcription Factors | 2007 |
Involvement of the lateral septum and the ventral Hippocampus in the emotional sequelae induced by social defeat: role of glucocorticoid receptors.
Topics: Aggression; Analysis of Variance; Anesthetics, Local; Animals; Behavior, Animal; Dominance-Subordination; Emotions; Hippocampus; Hormone Antagonists; Lidocaine; Male; Maze Learning; Mifepristone; Oncogene Proteins v-fos; Rats; Rats, Wistar; Reaction Time; Receptors, Glucocorticoid; Septal Nuclei; Spironolactone; Stress, Psychological | 2007 |
Life-threatening Pneumocystis jiroveci pneumonia following treatment of severe Cushing's syndrome.
Topics: Cushing Syndrome; Disease Progression; Fatal Outcome; Female; Humans; Ketoconazole; Middle Aged; Mifepristone; Opportunistic Infections; Pneumocystis carinii; Pneumonia, Pneumocystis; Risk Factors; Spironolactone | 2007 |
Does glucocorticoid receptor blockade exacerbate tissue damage after mineralocorticoid/salt administration?
Topics: Animals; Biomarkers; Blood Pressure; Cardiomegaly; Cardiomyopathies; Coronary Vessels; Desoxycorticosterone; Drug Administration Schedule; Eplerenone; Fibrosis; Hormone Antagonists; Male; Mifepristone; Myocardium; Organ Size; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Signal Transduction; Sodium Chloride; Spironolactone; Vasculitis | 2007 |
Aldosterone induces elastin production in cardiac fibroblasts through activation of insulin-like growth factor-I receptors in a mineralocorticoid receptor-independent manner.
Topics: Aldosterone; Animals; Cells, Cultured; Collagen Type I; Elastin; Fibroblasts; Gene Expression Regulation; Hormone Antagonists; Humans; Mifepristone; Mineralocorticoid Receptor Antagonists; Myocardium; Phosphorylation; Receptor, IGF Type 1; Receptors, Mineralocorticoid; Spironolactone; Tropoelastin; Tyrosine | 2007 |
Central mineralocorticoid receptors are indispensable for corticosterone-induced impairment of memory retrieval in rats.
Topics: Animals; Anisomycin; Behavior, Animal; Corticosterone; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Interactions; Hormone Antagonists; Male; Maze Learning; Memory Disorders; Mifepristone; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Receptors, Mineralocorticoid; Spironolactone; Swimming | 2007 |
Oxidative stress and the genomic regulation of aldosterone-stimulated NHE1 activity in SHR renal proximal tubular cells.
Topics: Aldosterone; Amiloride; Animals; Cell Line; Cytochalasin B; Dactinomycin; Gene Expression Regulation; Genome; Guanidines; Hydrogen Peroxide; Hydrogen-Ion Concentration; Immunoblotting; Kidney Tubules, Proximal; Methacrylates; Mifepristone; Oxidative Stress; Protein Isoforms; Rats; Rats, Inbred SHR; Receptors, Mineralocorticoid; RNA, Messenger; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; Spironolactone; Sulfones | 2008 |
Sub-chronic stimulation of glucocorticoid receptor impairs and mineralocorticoid receptor protects cytosolic Ca2+ responses to glucose in pancreatic beta-cells.
Topics: Aldosterone; Animals; Calcium; Corticosterone; Cytosol; Dose-Response Relationship, Drug; Female; Glucose; Insulin; Insulin Secretion; Insulin-Secreting Cells; Mifepristone; Pertussis Toxin; Pregnancy; Rats; Rats, Wistar; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone | 2008 |
Carbenoxolone impairs LTP and blocks NMDA receptors in murine hippocampus.
Topics: Adrenal Cortex Hormones; Animals; Calcium Channel Blockers; Carbenoxolone; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; Hormone Antagonists; In Vitro Techniques; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; Mifepristone; Receptors, N-Methyl-D-Aspartate; Spironolactone; Taurine | 2008 |
Cocaine decreases the expression of PSA-NCAM protein and attenuates long-term potentiation via glucocorticoid receptors in the rat dentate gyrus.
Topics: Animals; Bromodeoxyuridine; Cell Count; Cell Proliferation; Cocaine; Cocaine-Related Disorders; Corticosterone; Dentate Gyrus; Dopamine Uptake Inhibitors; Down-Regulation; Ki-67 Antigen; Long-Term Potentiation; Male; Memory; Memory Disorders; Metyrapone; Mifepristone; Mineralocorticoid Receptor Antagonists; Neural Cell Adhesion Molecule L1; Neurons; Rats; Rats, Wistar; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Sialic Acids; Spironolactone | 2008 |
Genomic and nongenomic dose-dependent biphasic effect of aldosterone on Na+/H+ exchanger in proximal S3 segment: role of cytosolic calcium.
Topics: Aldosterone; Ammonium Chloride; Animals; Calcium; Calcium Signaling; Cycloheximide; Cytosol; Dactinomycin; Gene Expression; Guanidines; Hydrogen-Ion Concentration; In Vitro Techniques; Kidney Tubules, Proximal; Male; Methacrylates; Mifepristone; Rats; Rats, Wistar; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Reverse Transcriptase Polymerase Chain Reaction; Sodium; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; Spironolactone; Sulfones | 2008 |
Mineralocorticoid and glucocorticoid receptors in the amygdala regulate distinct responses to colorectal distension.
Topics: Action Potentials; Amygdala; Animals; Biophysics; Blood Pressure; Cholesterol; Colon; Glucocorticoids; Heart Rate; Hormone Antagonists; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Physical Stimulation; Posterior Horn Cells; Rats; Rats, Inbred F344; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone | 2009 |
Stressor and glucocorticoid-dependent induction of the immediate early gene kruppel-like factor 9: implications for neural development and plasticity.
Topics: Animals; Brain; Cell Line; Corticosterone; Gene Expression; Glucocorticoids; Immunohistochemistry; Kruppel-Like Transcription Factors; Mifepristone; Mineralocorticoid Receptor Antagonists; Neurons; Polymerase Chain Reaction; Radioimmunoassay; Receptors, Glucocorticoid; Spironolactone; Stress, Physiological; Transfection; Xenopus laevis | 2009 |
Activation of glucocorticoid receptors increases 5-HT2A receptor levels.
Topics: Analysis of Variance; Animals; Autoradiography; Corticosterone; Fluorobenzenes; Gene Expression Regulation; Hippocampus; Hormone Antagonists; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mifepristone; Mineralocorticoid Receptor Antagonists; Piperidines; Protein Binding; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Glucocorticoid; Serotonin Plasma Membrane Transport Proteins; Spironolactone; Tissue Culture Techniques; Tritium | 2009 |
Effects of cortisol, growth hormone and prolactin on gill claudin expression in Atlantic salmon.
Topics: Animals; Gene Expression Regulation; Gills; Growth Hormone; Hormone Antagonists; Hydrocortisone; Membrane Proteins; Mifepristone; Mineralocorticoid Receptor Antagonists; Polymerase Chain Reaction; Prolactin; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Salmo salar; Spironolactone; Water-Electrolyte Balance | 2009 |
Modulation of presynaptic glucocorticoid receptors on glutamate release from rat hippocampal nerve terminals.
Topics: 4-Aminopyridine; Adrenalectomy; Animals; Cortisone; Dexamethasone; Down-Regulation; Drug Administration Schedule; Glucocorticoids; Glutamic Acid; Hippocampus; Male; Mifepristone; Potassium Channel Blockers; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Spironolactone; Synaptic Membranes; Synaptic Transmission; Synaptosomes | 2009 |
Mineralocorticoid and glucocorticoid receptors stimulate epithelial sodium channel activity in a mouse model of Cushing syndrome.
Topics: Adrenocorticotropic Hormone; Animals; Blood Pressure; Cushing Syndrome; Disease Models, Animal; Epithelial Sodium Channels; Glomerular Filtration Rate; Hormone Antagonists; Loop of Henle; Male; Mice; Mice, Inbred C57BL; Mifepristone; Mineralocorticoid Receptor Antagonists; Receptors, Adrenergic, alpha-1; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Receptors, Vasopressin; Sodium; Sodium-Potassium-Chloride Symporters; Spironolactone | 2009 |
Mifepristone and spironolactone differently alter cocaine intravenous self-administration and cocaine-induced locomotion in C57BL/6J mice.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Diuretics; Hallucinogens; Hormone Antagonists; Injections, Intraperitoneal; Mice; Mice, Inbred C57BL; Mifepristone; Mineralocorticoid Receptor Antagonists; Motivation; Motor Activity; Receptors, Glucocorticoid; Self Administration; Spironolactone; Substance Abuse, Intravenous | 2010 |
Aggression in rainbow trout is inhibited by both MR and GR antagonists.
Topics: Aggression; Animals; Anti-Inflammatory Agents; Behavior, Animal; Drug Combinations; Enzyme Assays; Hormone Antagonists; Hydrocortisone; Interpersonal Relations; Mifepristone; Mineralocorticoid Receptor Antagonists; Oncorhynchus mykiss; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone; Statistics, Nonparametric; Video Recording | 2009 |
Glucocorticoids activate cardiac mineralocorticoid receptors during experimental myocardial infarction.
Topics: Aldosterone; Angina, Unstable; Animals; Apoptosis; Dexamethasone; Glucocorticoids; Hormone Antagonists; Hydrocortisone; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Myocardial Infarction; Myocardial Reperfusion Injury; Rats; Rats, Sprague-Dawley; Receptors, Mineralocorticoid; Spironolactone | 2009 |
Corticosterone up-regulates expression and function of norepinephrine transporter in SK-N-BE(2)C cells.
Topics: Animals; Anti-Inflammatory Agents; Cell Line, Transformed; Cell Line, Tumor; Corticosterone; Dose-Response Relationship, Drug; Hormone Antagonists; Humans; Mifepristone; Neuroblastoma; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Rats; RNA, Messenger; Spironolactone; Time Factors; Tritium; Up-Regulation | 2010 |
Aldosterone causes DNA strand breaks and chromosomal damage in renal cells, which are prevented by mineralocorticoid receptor antagonists.
Topics: Aldosterone; Animals; Cells, Cultured; Chromones; Chromosomes; Comet Assay; Cytoprotection; Dihydropyridines; DNA Breaks; DNA Damage; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Hormone Antagonists; Kidney; Micronucleus Tests; Mifepristone; Mineralocorticoid Receptor Antagonists; Spironolactone; Swine | 2010 |
Aldosterone and cortisol acutely stimulate Na+/H+ exchanger activity in the syncytiotrophoblast of the human placenta: effect of fetal sex.
Topics: Aldosterone; Female; Humans; Hydrocortisone; Infant, Newborn; Male; Mifepristone; Placenta; Pregnancy; Sex Factors; Sodium-Hydrogen Exchangers; Spironolactone; Trophoblasts | 2010 |
Stress within the postseizure time window inhibits seizure recurrence.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents; Anticonvulsants; Circadian Rhythm; Corticosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Hormone Antagonists; Kindling, Neurologic; Mifepristone; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Secondary Prevention; Seizures; Spironolactone; Stress, Physiological; Time Factors | 2010 |
Both mineralocorticoid and glucocorticoid receptors regulate emotional memory in mice.
Topics: Analysis of Variance; Animals; Association Learning; Avoidance Learning; Emotions; Fear; Gene Knockdown Techniques; Hormone Antagonists; Male; Memory; Mice; Mice, Inbred C57BL; Mifepristone; Prosencephalon; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone; Time Factors | 2010 |
Antidepressant-like effects of mineralocorticoid but not glucocorticoid antagonists in the lateral septum: interactions with the serotonergic system.
Topics: Animals; Antidepressive Agents; Clomipramine; Corticosterone; Drug Interactions; Fenclonine; Hydroxyindoleacetic Acid; Immobility Response, Tonic; Male; Microinjections; Mifepristone; Mineralocorticoid Receptor Antagonists; Rats; Rats, Wistar; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Septum of Brain; Serotonin; Spironolactone | 2011 |
The respective and interaction effects of spinal GRs and MRs on radicular pain induced by chronic compression of the dorsal root ganglion in the rat.
Topics: Animals; Dexamethasone; Disease Models, Animal; Drug Synergism; Ganglia, Spinal; Hormone Antagonists; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Radiculopathy; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone | 2011 |
Brief neck restraint stress enhances long-term potentiation and suppresses long-term depression in the dentate gyrus of the mouse.
Topics: Animals; Corticosterone; Dentate Gyrus; Enzyme Inhibitors; Hormone Antagonists; Long-Term Potentiation; Long-Term Synaptic Depression; Male; Metyrapone; Mice; Mice, Inbred C57BL; Mifepristone; Mineralocorticoid Receptor Antagonists; Neck; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Restraint, Physical; Spironolactone; Synaptic Transmission | 2011 |
Effects of aldosterone and related steroids on LPS-induced increased expression of inducible NOS in rat aortic smooth muscle cells.
Topics: Aldosterone; Animals; Aorta, Thoracic; Cells, Cultured; Eplerenone; Lipopolysaccharides; Male; Mifepristone; Muscle, Smooth, Vascular; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Spironolactone; Steroids | 2011 |
Glucocorticoid and mineralocorticoid receptors regulate paracellular permeability in a primary cultured gill epithelium.
Topics: Aldosterone; Animals; Cell Membrane Permeability; Cells, Cultured; Desoxycorticosterone; Dexamethasone; Electric Impedance; Epithelial Cells; Epithelium; Eplerenone; Fish Proteins; Gene Expression Regulation; Gills; Hydrocortisone; Mifepristone; Mineralocorticoid Receptor Antagonists; Oncorhynchus mykiss; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spironolactone; Tight Junctions | 2011 |
Evidence for transcriptional regulation of the urea transporter in the gill of the Gulf toadfish, Opsanus beta.
Topics: Animals; Antimetabolites; Base Sequence; Batrachoidiformes; Gene Expression Regulation; Gills; Hormone Antagonists; Hydrocortisone; Membrane Transport Proteins; Metyrapone; Mifepristone; Molecular Sequence Data; Phylogeny; Promoter Regions, Genetic; Receptors, Glucocorticoid; Spironolactone; Tissue Distribution; Transcription, Genetic; Urea; Urea Transporters | 2011 |
Adipocyte-derived factors regulate vascular smooth muscle cells through mineralocorticoid and glucocorticoid receptors.
Topics: 3T3-L1 Cells; Adipocytes; Aldosterone; Angiotensin II; Animals; Blotting, Western; Cells, Cultured; Corticosterone; Culture Media, Conditioned; Eplerenone; Fadrozole; Fibronectins; Hormone Antagonists; Mice; Mice, Inbred C57BL; Mifepristone; Mineralocorticoid Receptor Antagonists; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-bcl-2; Receptor, Angiotensin, Type 1; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone | 2011 |
Glucocorticoids are critical regulators of dendritic spine development and plasticity in vivo.
Topics: Age Factors; Animals; Corticosterone; Dendritic Spines; Dexamethasone; Dose-Response Relationship, Drug; Glucocorticoids; Hormone Antagonists; Luminescent Proteins; Mice; Mice, Transgenic; Microscopy, Fluorescence, Multiphoton; Mifepristone; Mineralocorticoid Receptor Antagonists; Motor Cortex; Neuronal Plasticity; Receptors, Steroid; Somatosensory Cortex; Spironolactone; Time Factors | 2011 |
Blocking mineralocorticoid receptors prior to retrieval reduces contextual fear memory in mice.
Topics: Animals; Cues; Fear; Male; Mental Recall; Mice; Mice, Inbred C57BL; Mifepristone; Mineralocorticoid Receptor Antagonists; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone | 2011 |
Blockade of mineralocorticoid and glucocorticoid receptors reverses stress-induced motor impairments.
Topics: Aldosterone; Animals; Blood Glucose; Corticosterone; Dexamethasone; Female; Hormone Antagonists; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Motor Activity; Motor Skills; Rats; Receptors, Glucocorticoid; Restraint, Physical; Spironolactone; Stress, Physiological | 2011 |
Differential involvement of amygdala corticosteroid receptors in visceral hyperalgesia following acute or repeated stress.
Topics: Amygdala; Animals; Colon; Hormone Antagonists; Hyperalgesia; Irritable Bowel Syndrome; Male; Mifepristone; Rats; Rats, Inbred F344; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone; Stress, Psychological | 2012 |
Action of ANP on the nongenomic dose-dependent biphasic effect of aldosterone on NHE1 in proximal S3 segment.
Topics: Acid-Base Equilibrium; Aldosterone; Ammonium Chloride; Animals; Atrial Natriuretic Factor; Calcium Signaling; Chelating Agents; Hydrogen-Ion Concentration; In Vitro Techniques; Kidney Tubules, Proximal; Kinetics; Male; Microdissection; Mifepristone; Mineralocorticoid Receptor Antagonists; Osmolar Concentration; Rats; Rats, Wistar; Receptors, Glucocorticoid; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; Spironolactone | 2012 |
Dexamethasone stimulates endothelin-1 gene expression in renal collecting duct cells.
Topics: Animals; Blotting, Western; Cell Line; Dexamethasone; Dose-Response Relationship, Drug; Endothelin-1; Gene Expression; Glucocorticoids; Hormone Antagonists; Kidney Tubules, Collecting; Mifepristone; Mineralocorticoid Receptor Antagonists; Mutation; Promoter Regions, Genetic; Protein Binding; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Response Elements; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Messenger; Spironolactone | 2012 |
Stress and corticosteroid modulation of seizures and synaptic inhibition in the hippocampus.
Topics: Adrenal Cortex Hormones; Aldosterone; Animals; Biophysics; Disease Models, Animal; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Hippocampus; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Kainic Acid; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Neural Inhibition; Patch-Clamp Techniques; Rats; Rats, Wistar; Reaction Time; Seizures; Spironolactone; Stress, Psychological; Synapses; Time Factors | 2012 |
Contribution of glucocorticoid-mineralocorticoid receptor pathway on the obesity-related adipocyte dysfunction.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 3T3-L1 Cells; Adipocytes; Adipokines; Animals; Body Mass Index; Eplerenone; Glucocorticoids; Humans; Male; Metabolic Networks and Pathways; Mice; Mice, Mutant Strains; Mifepristone; Mineralocorticoid Receptor Antagonists; Obesity; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; RNA, Small Interfering; Spironolactone | 2012 |
Acute exposure to a novel stressor further reduces the habituated corticosterone response to restraint in rats.
Topics: Animals; Behavior, Animal; Corticosterone; Feedback, Physiological; Habituation, Psychophysiologic; Hormone Antagonists; Hypothalamo-Hypophyseal System; Injections; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Pituitary-Adrenal System; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Restraint, Physical; Spironolactone; Stress, Psychological; Time Factors | 2001 |
T-type Ca²⁺ signalling downregulates MEK1/2 phosphorylation and cross-talk with the RAAS transcriptional response in cardiac myocytes.
Topics: Animals; Calcium Signaling; Flunarizine; Fluoxetine; Male; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mibefradil; Mifepristone; Mineralocorticoid Receptor Antagonists; Myocytes, Cardiac; Nifedipine; Phosphorylation; Rats; Rats, Wistar; Receptors, Glucocorticoid; Renin-Angiotensin System; Spironolactone | 2012 |
Corticosterone suppresses the proliferation of BV2 microglia cells via glucocorticoid, but not mineralocorticoid receptor.
Topics: Animals; Anti-Inflammatory Agents; Cell Line; Cell Proliferation; Corticosterone; L-Lactate Dehydrogenase; Membrane Potential, Mitochondrial; Mice; Microglia; Mifepristone; Mineralocorticoid Receptor Antagonists; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone | 2012 |
Effects of acute restraint stress on set-shifting and reversal learning in male rats.
Topics: Animals; Conditioning, Operant; Executive Function; Hormone Antagonists; Hypothalamo-Hypophyseal System; Male; Mifepristone; Pituitary-Adrenal System; Rats; Rats, Sprague-Dawley; Restraint, Physical; Reversal Learning; Set, Psychology; Spironolactone; Stress, Psychological | 2013 |
Corticosterone suppresses the proliferation of RAW264.7 macrophage cells via glucocorticoid, but not mineralocorticoid, receptor.
Topics: Animals; Cell Line; Cell Proliferation; Corticosterone; Hormone Antagonists; Macrophages; Membrane Potential, Mitochondrial; Mice; Mifepristone; Mineralocorticoid Receptor Antagonists; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone | 2013 |
Effects of chronic social defeat on expression of dopamine β-hydroxylase in rat brains.
Topics: Adrenalectomy; Animals; Antidepressive Agents; Brain; Desipramine; Dopamine beta-Hydroxylase; Fluoxetine; Hormone Antagonists; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Rats; Rats, Inbred F344; Rats, Long-Evans; RNA, Messenger; Social Behavior; Spironolactone; Stress, Psychological; Transcription, Genetic; Up-Regulation | 2013 |
Glucocorticoid-induced hypertension and cardiac injury: effects of mineralocorticoid and glucocorticoid receptor antagonism.
Topics: Animals; Atrophy; Blood Pressure; Corticosterone; Disease Models, Animal; Fibrosis; Heart Diseases; Hypertension; Inflammation Mediators; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Myocardium; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone; Time Factors; Ventricular Dysfunction, Left; Ventricular Function, Left | 2013 |
Blockade of corticosteroid receptors induces anxiolytic-like effects in streptozotocin-induced diabetic mice, and synergizes with diazepam.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Blood Glucose; Diabetes Mellitus, Experimental; Diazepam; Dose-Response Relationship, Drug; Drug Synergism; Hormone Antagonists; Mice; Mifepristone; Mineralocorticoid Receptor Antagonists; Motor Activity; Receptors, Steroid; Spironolactone; Time Factors | 2013 |
Cocaine- or stress-induced metaplasticity of LTP in the dorsal and ventral hippocampus.
Topics: Animals; Cocaine; Corticosterone; Dopamine Uptake Inhibitors; Drug Administration Schedule; Excitatory Postsynaptic Potentials; Hippocampus; Hormone Antagonists; In Vitro Techniques; Long-Term Potentiation; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Motor Activity; Naltrexone; Rats; Rats, Sprague-Dawley; Spironolactone; Stress, Psychological | 2014 |
Corticosteroid-endocannabinoid loop supports decrease of fear-conditioned response in rats.
Topics: Adrenal Cortex Hormones; Animals; Arachidonic Acids; Benzoxazines; Cannabinoid Receptor Modulators; Conditioning, Classical; Dexamethasone; Endocannabinoids; Extinction, Psychological; Fear; Freezing Reaction, Cataleptic; Male; Metyrapone; Mifepristone; Mineralocorticoid Receptor Antagonists; Morpholines; Naphthalenes; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Glucocorticoid; Rimonabant; Spironolactone | 2014 |
Glucocorticoid receptor antagonism disrupts the reconsolidation of social reward-related memories in rats.
Topics: Analysis of Variance; Animals; Cannabinoid Receptor Antagonists; Conditioning, Operant; Dizocilpine Maleate; Dose-Response Relationship, Drug; Hormone Antagonists; Male; Memory Disorders; Mifepristone; Mineralocorticoid Receptor Antagonists; Neuroprotective Agents; Piperidines; Pyrazoles; Rats; Rats, Wistar; Reward; Rimonabant; Social Behavior; Spironolactone | 2014 |
Rapid Activation of Glucocorticoid Receptors in the Prefrontal Cortex Mediates the Expression of Contextual Conditioned Fear in Rats.
Topics: Animals; Conditioning, Psychological; Corticosterone; Enzyme Inhibitors; Fear; Freezing Reaction, Cataleptic; Hormone Antagonists; Male; Metyrapone; Mifepristone; Prefrontal Cortex; Proto-Oncogene Proteins c-fos; Rats, Wistar; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone | 2016 |
Cortisol stimulates arginine vasotocin and isotocin release from the hypothalamo-pituitary complex of round goby (Neogobius melanostomus): Probable mechanisms of action.
Topics: Animals; Dactinomycin; Female; Hydrocortisone; Hypothalamus; In Vitro Techniques; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Oxytocin; Perciformes; Pituitary Gland; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone; Vasotocin | 2015 |
Glucocorticoid receptor but not mineralocorticoid receptor mediates the activation of ERK pathway and CREB during morphine withdrawal.
Topics: Analgesics, Opioid; Animals; Cyclic AMP Response Element-Binding Protein; Dopamine; Hormone Antagonists; Male; MAP Kinase Signaling System; Mifepristone; Mineralocorticoid Receptor Antagonists; Morphine; Naloxone; Narcotic Antagonists; Nucleus Accumbens; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone; Substance Withdrawal Syndrome; Tyrosine 3-Monooxygenase | 2017 |
Treadmill exercise ameliorates ischemia-induced brain edema while suppressing Na⁺/H⁺ exchanger 1 expression.
Topics: Acid Sensing Ion Channel Blockers; Animals; Aquaporin 4; Brain Edema; Cells, Cultured; Corticosterone; Cytokines; Disease Models, Animal; Exercise Therapy; Functional Laterality; Gene Expression Regulation; Infarction, Middle Cerebral Artery; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Nerve Tissue Proteins; Neuroglia; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers; Spironolactone; Time Factors | 2016 |
Estradiol and corticosterone stimulate the proliferation of a GH cell line, MtT/S: Proliferation of growth hormone cells.
Topics: Animals; Cell Line; Cell Proliferation; Corticosterone; Estradiol; Estrogen Receptor Antagonists; Estrogens; Fulvestrant; Glucocorticoids; Growth Hormone; Hormone Antagonists; Mifepristone; Mineralocorticoid Receptor Antagonists; Rats; Real-Time Polymerase Chain Reaction; RNA, Messenger; Serum Albumin, Bovine; Somatotrophs; Spironolactone | 2016 |
A novel role for the mineralocorticoid receptor in glucocorticoid driven vascular calcification.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Apoptosis; Corticosterone; Disease Models, Animal; Eplerenone; Flow Cytometry; Glucocorticoids; Mice; Mice, Inbred C57BL; Mifepristone; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphates; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; RNA, Messenger; Spironolactone; Vascular Calcification | 2016 |
Differential effects of glucocorticoid and mineralocorticoid antagonism on anxiety behavior in mild traumatic brain injury.
Topics: Animals; Anxiety; Brain Concussion; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone; Stress, Psychological | 2016 |
Corticosterone Inhibits the Proliferation of C6 Glioma Cells via the Translocation of Unphosphorylated Glucocorticoid Receptor.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cell Survival; Corticosterone; Glioma; Hormone Antagonists; Membrane Potential, Mitochondrial; Mifepristone; Rats; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone | 2016 |
Cortisol Induces Reactive Oxygen Species Through a Membrane Glucocorticoid Receptor in Rainbow Trout Myotubes.
Topics: Animals; Cyclic AMP Response Element-Binding Protein; Fish Proteins; Hormone Antagonists; Hydrocortisone; MAP Kinase Signaling System; Mifepristone; Models, Biological; Muscle Fibers, Skeletal; Oncorhynchus mykiss; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Reactive Oxygen Species; Receptors, Glucocorticoid; Spironolactone; Stress, Physiological | 2017 |
Context-dependent memory following recurrent hypoglycaemia in non-diabetic rats is mediated via glucocorticoid signalling in the dorsal hippocampus.
Topics: Animals; Corticosterone; Glucocorticoids; Hippocampus; Hypoglycemia; Male; Mifepristone; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, N-Methyl-D-Aspartate; Spironolactone | 2017 |
Modulation of Rat 50-kHz Ultrasonic Vocalizations by Glucocorticoid Signaling: Possible Relevance to Reward and Motivation.
Topics: Amphetamine; Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glucocorticoids; Hormone Antagonists; Male; Metyrapone; Mifepristone; Motivation; Rats; Rats, Sprague-Dawley; Reward; Signal Transduction; Spironolactone; Ultrasonics; Vocalization, Animal | 2018 |
11β-hydroxysteroid dehydrogenase type 1 inhibitor attenuates high-fat diet induced cardiomyopathy.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Animals, Newborn; Calcium Signaling; Cardiomyopathies; Diet, High-Fat; Glucose Tolerance Test; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Myocytes, Cardiac; Palmitic Acid; Rats; Rats, Wistar; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone | 2018 |
Involvement of glucocorticoid and mineralocorticoid receptors in lipid accumulation and depressed G6PD activity in the livers of rats treated with postpartum oral estrogen-progestin.
Topics: Animals; Contraceptives, Oral, Hormonal; Estrogens; Ethinyl Estradiol; Female; Glucose; Glucosephosphate Dehydrogenase; Levonorgestrel; Lipid Metabolism; Liver; Mifepristone; Mineralocorticoid Receptor Antagonists; Pregnancy; Progestins; Rats; Rats, Wistar; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone | 2019 |
Glucocorticoid receptor activation stimulates the sodium-chloride cotransporter and influences the diurnal rhythm of its phosphorylation.
Topics: Adrenalectomy; Animals; Circadian Rhythm; CLOCK Proteins; Corticosterone; Kidney; Male; Mice; Mice, Inbred C57BL; Mifepristone; Mineralocorticoid Receptor Antagonists; Phosphorylation; Receptors, Glucocorticoid; Sodium Chloride Symporters; Spironolactone | 2019 |
Early post-stress administration of MR or GR antagonist in adolescent female rats restored anxiogenic-like behavior and modified the HPA axis response in the adulthood.
Topics: Animals; Anxiety; Corticosterone; Corticotropin-Releasing Hormone; Female; Glucocorticoids; Hypothalamo-Hypophyseal System; Mifepristone; Mineralocorticoid Receptor Antagonists; Pituitary-Adrenal System; Rats; Receptors, Glucocorticoid; Spironolactone; Stress, Psychological | 2022 |
Combined antagonist treatment of glucocorticoid and mineralocorticoid receptor does not affect weight loss of fasting rainbow trout but inhibits a fasting-induced elevation of cortisol secretion.
Topics: Animals; Fasting; Glucocorticoids; Hydrocortisone; Mifepristone; Mineralocorticoid Receptor Antagonists; Oncorhynchus mykiss; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone; Weight Loss | 2022 |
Corticosterone injection into the dorsal and ventral hippocampus impairs fear memory reconsolidation in a time-dependent manner in rats.
Topics: Animals; Corticosterone; Fear; Hippocampus; Male; Mifepristone; Rats; Rats, Wistar; Receptors, Glucocorticoid; Spironolactone | 2023 |
Ambiguous Contribution of Glucocorticosteroids to Acute Neuroinflammation in the Hippocampus of Rat.
Topics: Animals; Dexamethasone; Hippocampus; Lipopolysaccharides; Male; Mifepristone; Neuroinflammatory Diseases; Rats; Rats, Wistar; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone | 2023 |