Page last updated: 2024-08-17

spironolactone and methyltestosterone

spironolactone has been researched along with methyltestosterone in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19904 (57.14)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ernst, B; Lill, MA; Vedani, A; Winiger, F1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Gillette, JR; Hamrick, ME; Stripp, B; Zampaglione, NG2
Gillette, JR; Menard, RH; Stripp, B1
Jelinek, J; Krajny, M; Selye, H1

Reviews

1 review(s) available for spironolactone and methyltestosterone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

6 other study(ies) available for spironolactone and methyltestosterone

ArticleYear
Impact of induced fit on ligand binding to the androgen receptor: a multidimensional QSAR study to predict endocrine-disrupting effects of environmental chemicals.
    Journal of medicinal chemistry, 2005, Sep-08, Volume: 48, Issue:18

    Topics: Benzhydryl Compounds; Binding Sites; Diethylstilbestrol; Endocrine System; Hydrocarbons, Chlorinated; Ligands; Models, Molecular; Molecular Conformation; Phenols; Phytoestrogens; Quantitative Structure-Activity Relationship; Receptors, Androgen; Testosterone; Thermodynamics; Xenobiotics

2005
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Investigation of the effects of methyltestosterone, cortisone and spironolactone on the hepatic microsomal mixed function oxidase system in male and female rats.
    Biochemical pharmacology, 1973, Feb-01, Volume: 22, Issue:3

    Topics: Animals; Cortisone; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Female; Hexobarbital; Kinetics; Male; Methyltestosterone; Microsomes, Liver; Morphinans; NADP; Organ Size; Oxidoreductases; Protein Binding; Rats; Seminal Vesicles; Sex Factors; Spironolactone; Time Factors; Uterus

1973
Spironolactone and testicular cytochrome P-450: decreased testosterone formation in several species and changes in hepatic drug metabolism.
    Endocrinology, 1974, Volume: 94, Issue:6

    Topics: Animals; Carbon Radioisotopes; Cytochrome P-450 Enzyme System; Cytochromes; Dogs; Female; Guinea Pigs; Heme; Liver; Male; Methyltestosterone; Mice; Microsomes; Pregnenolone; Progesterone; Rabbits; Rats; Spironolactone; Steroid Hydroxylases; Testis; Testosterone

1974
The effect of spironolactone on drug metabolism by hepatic microsomes.
    The Journal of pharmacology and experimental therapeutics, 1971, Volume: 176, Issue:3

    Topics: Adrenalectomy; Animals; Benzopyrenes; Castration; Cytochromes; Dealkylation; Electron Transport; Enzyme Induction; Female; Hexobarbital; Hydroxylation; Kinetics; Male; Methyltestosterone; Microsomes, Liver; Morphinans; Oxidoreductases; Pharmaceutical Preparations; Rats; Sex Factors; Sleep; Spironolactone

1971
Prevention of digitoxin poisoning by various steroids.
    Journal of pharmaceutical sciences, 1969, Volume: 58, Issue:9

    Topics: Anabolic Agents; Androstanes; Animals; Body Weight; Desoxycorticosterone; Digitoxin; Diuretics; Estradiol; Ethisterone; Ethylestrenol; Female; Fluoxymesterone; Hydrocortisone; Ketones; Methyltestosterone; Nandrolone; Norethandrolone; Norethynodrel; Organ Size; Oxandrolone; Oxymetholone; Poisoning; Pregnanes; Pregnenolone; Progesterone; Pyrazines; Rats; Spironolactone; Testosterone; Triamterene

1969