Page last updated: 2024-08-17

spironolactone and lisinopril

spironolactone has been researched along with lisinopril in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's12 (38.71)29.6817
2010's17 (54.84)24.3611
2020's2 (6.45)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bellorini, M; Desnos, M; Duboc, D; Funck, F; Guillard, N; Jourdain, P; Loiret, J; Thebault, B1
Chapon, C; Furber, A; Kreher, P; Le Bouil, A; Marescaux, L; Rochetaing, A1
Challande, P; Delcayre, C; Labat, C; Lacolley, P; Leenhardt, A; Milliez, P; Nehme, JA; Perret, C; Robidel, E; Safar, ME1
Cohen-Solal, A; Dietz, R; Eichhorn, E; Erhardt, L; Hobbs, FD; Krum, H; Maggioni, A; McKelvie, RS; McMurray, J; Piña, IL; Soler-Soler, J; Swedberg, K1
Ahn, J; Frohlich, ED; Matavelli, LC; Susic, D; Varagic, J1
Altenberger, H; Finsterer, J; Stöllberger, C1
Parker, T1
Gutiérrez Solís, E; Gutiérrez, E; Huerta, A; Morales, E; Praga, M; Segura, J1
Briganti, C; Caulo, M; Notturno, F; Tartaro, A; Uncini, A1
Adams-Huet, B; Mehdi, UF; Raskin, P; Toto, RD; Vega, GL1
Adefehinti, O; Adelusola, KA; Olowu, WA1
Canan, BD; Chimanji, NS; Delfín, DA; Ganguly, R; Janssen, PM; Martin, CD; Mays, TA; Murray, JD; Rafael-Fortney, JA; Raman, SV; Schill, KE; Stangland, JE; Tran, T; Xu, Y1
Fayssoil, A1
Ahmad, T; Milano, CA; Patel, CB; Rogers, JG1
Handler, J1
Adams-Huet, B; Molina, C; Nguyen, M; Toto, RD; Van Buren, PN1
Fried, LF; Seliger, SL1
Janssen, PM; Murray, JD; Rafael-Fortney, JA; Raman, SV; Rastogi, N; Schill, KE; Schultz, EJ; Tran, T1
Chadwick, JA; Gomez-Sanchez, CE; Gomez-Sanchez, EP; Guttridge, DC; Hauck, JS; Lowe, J; Rafael-Fortney, JA; Shaw, JJ1
Chadwick, JA; Floyd, KT; Gomez-Sanchez, CE; Gomez-Sanchez, EP; Janssen, PM; Kadakia, FK; Lowe, J; Rafael-Fortney, JA; Raman, SV; Rastogi, N; Schultz, EJ; Smart, S; Swager, SA; Zins, JG1
Bhattacharya, S; Chadwick, JA; Lowe, J; Rafael-Fortney, JA; Weisleder, N1
Paulus, R; Schmidt, B1
Booz, C; Buchner, K; Eichler, K; Frey, N; Gruber-Rouh, T; Gruenewald, LD; Hagenmueller, M; Hardt, SE; Koch, V; Martin, S; März, W; Riffel, JH; Vogl, TJ; Yel, I1

Reviews

1 review(s) available for spironolactone and lisinopril

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

3 trial(s) available for spironolactone and lisinopril

ArticleYear
[The antiproteinuric effect of the blockage of the renin-angiotensin-aldosterone system (RAAS) in obese patients. Which treatment option is the most effective? ].
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2009, Volume: 29, Issue:5

    Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Eplerenone; Female; Humans; Lisinopril; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Obesity; Prospective Studies; Proteinuria; Spironolactone; Tetrazoles

2009
Addition of angiotensin receptor blockade or mineralocorticoid antagonism to maximal angiotensin-converting enzyme inhibition in diabetic nephropathy.
    Journal of the American Society of Nephrology : JASN, 2009, Volume: 20, Issue:12

    Topics: Adult; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Bicarbonates; Blood Pressure; Creatinine; Diabetic Nephropathies; Double-Blind Method; Drug Therapy, Combination; Female; Glycated Hemoglobin; Humans; Hypertension; Lisinopril; Losartan; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Potassium; Renin-Angiotensin System; Spironolactone

2009
Potassium handling with dual renin-angiotensin system inhibition in diabetic nephropathy.
    Clinical journal of the American Society of Nephrology : CJASN, 2014, Volume: 9, Issue:2

    Topics: Adult; Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Biomarkers; Creatinine; Diabetic Nephropathies; Diuretics; Drug Therapy, Combination; Female; Humans; Hyperkalemia; Lisinopril; Losartan; Male; Middle Aged; Potassium; Prospective Studies; Renin-Angiotensin System; Risk Factors; Sodium; Spironolactone; Texas; Time Factors; Treatment Outcome

2014

Other Studies

27 other study(ies) available for spironolactone and lisinopril

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Bedside B-type natriuretic peptide and functional capacity in chronic heart failure.
    European journal of heart failure, 2003, Volume: 5, Issue:2

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Atrial Natriuretic Factor; Biomarkers; Carbazoles; Carvedilol; Chronic Disease; Diuretics; Dose-Response Relationship, Drug; Follow-Up Studies; France; Furosemide; Heart Failure; Humans; Incidence; Lisinopril; Middle Aged; Natriuretic Peptide, Brain; Propanolamines; Severity of Illness Index; Spironolactone; Stroke Volume; Treatment Outcome

2003
Potential beneficial as well as detrimental effects of chronic treatment with lisinopril and (or) spironolactone on isolated hearts following low-flow ischemia in normal and infarcted rats.
    Canadian journal of physiology and pharmacology, 2003, Volume: 81, Issue:9

    Topics: Action Potentials; Animals; Cardiotonic Agents; Coronary Circulation; Drug Therapy, Combination; Electrophysiologic Techniques, Cardiac; In Vitro Techniques; Lisinopril; Male; Myocardial Infarction; Myocardial Ischemia; Myocardium; Norepinephrine; Potassium; Rats; Rats, Wistar; Spironolactone; Ventricular Function, Left

2003
Spironolactone improves carotid artery fibrosis and distensibility in rat post-ischaemic heart failure.
    Journal of molecular and cellular cardiology, 2005, Volume: 39, Issue:3

    Topics: Animals; Carotid Arteries; Compliance; Drug Therapy, Combination; Echocardiography; Elasticity; Fibrosis; Heart Failure; Lisinopril; Male; Myocardial Ischemia; Random Allocation; Rats; Rats, Wistar; Spironolactone; Time Factors; Ventricular Function, Left

2005
Practical recommendations for the use of ACE inhibitors, beta-blockers, aldosterone antagonists and angiotensin receptor blockers in heart failure: putting guidelines into practice.
    European journal of heart failure, 2005, Volume: 7, Issue:5

    Topics: Adrenergic beta-Antagonists; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Benzopyrans; Biphenyl Compounds; Bisoprolol; Captopril; Carbazoles; Carvedilol; Drug Therapy, Combination; Enalapril; Ethanolamines; Evidence-Based Medicine; Guideline Adherence; Heart Failure; Humans; Indoles; Lisinopril; Metoprolol; Mineralocorticoid Receptor Antagonists; Nebivolol; Practice Guidelines as Topic; Propanolamines; Ramipril; Spironolactone; Stroke Volume; Tetrazoles; Valine; Valsartan

2005
Beneficial cardiovascular actions of eplerenone in the spontaneously hypertensive rat.
    Journal of cardiovascular pharmacology and therapeutics, 2005, Volume: 10, Issue:3

    Topics: Animals; Blood Pressure; Coronary Circulation; Eplerenone; Hypertension; Lisinopril; Male; Rats; Rats, Inbred SHR; Spironolactone; Vascular Resistance

2005
Isolated left ventricular hypertrabeculation/noncompaction in a Turner mosaic with male phenotype.
    Acta cardiologica, 2009, Volume: 64, Issue:1

    Topics: Adrenergic alpha-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Carbazoles; Cardiomyopathy, Dilated; Cardiotonic Agents; Carvedilol; Digoxin; Diuretics; Echocardiography; Furosemide; Heart Ventricles; Humans; Lisinopril; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Mosaicism; Phenotype; Propanolamines; Spironolactone; Turner Syndrome; Ventricular Dysfunction, Left

2009
Case of the month. Idiopathic dilated cardiomyopathy.
    JAAPA : official journal of the American Academy of Physician Assistants, 2009, Volume: 22, Issue:7

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aged; Angiography; Angiotensin-Converting Enzyme Inhibitors; Atorvastatin; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Clopidogrel; Diuretics; Dyspnea; Echocardiography; Electrocardiography; Furosemide; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lisinopril; Male; Mineralocorticoid Receptor Antagonists; Platelet Aggregation Inhibitors; Potassium; Propanolamines; Pyrroles; Spironolactone; Ticlopidine

2009
Asymptomatic spinal cord involvement in posterior reversible encephalopathy syndrome.
    Neurology, 2009, Nov-03, Volume: 73, Issue:18

    Topics: Adult; Antihypertensive Agents; Blood Pressure; Cervical Vertebrae; Female; Humans; Lisinopril; Posterior Leukoencephalopathy Syndrome; Spinal Cord; Spironolactone; Treatment Outcome

2009
Childhood idiopathic steroid resistant nephrotic syndrome in Southwestern Nigeria.
    Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia, 2010, Volume: 21, Issue:5

    Topics: Adolescent; Angiotensin-Converting Enzyme Inhibitors; Child; Child, Preschool; Cyclophosphamide; Dexamethasone; Disease-Free Survival; Drug Resistance; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Kaplan-Meier Estimate; Lisinopril; Male; Mineralocorticoid Receptor Antagonists; Nephrotic Syndrome; Nigeria; Prevalence; Pulse Therapy, Drug; Recurrence; Regression Analysis; Retrospective Studies; Spironolactone; Steroids; Time Factors; Treatment Failure

2010
Early treatment with lisinopril and spironolactone preserves cardiac and skeletal muscle in Duchenne muscular dystrophy mice.
    Circulation, 2011, Aug-02, Volume: 124, Issue:5

    Topics: Animals; Cardiac Imaging Techniques; Cardiomyopathies; Cardiotonic Agents; Disease Models, Animal; Diuretics; Isoproterenol; Lisinopril; Magnetic Resonance Imaging; Mice; Mice, Inbred mdx; Muscle, Skeletal; Muscular Dystrophy, Duchenne; Myocardium; Spironolactone

2011
Letter by Fayssoil regarding article, "Early treatment with lisinopril and spironolactone preserves cardiac and skeletal muscle in Duchenne muscular dystrophy mice".
    Circulation, 2012, Mar-06, Volume: 125, Issue:9

    Topics: Animals; Lisinopril; Muscle, Skeletal; Muscular Dystrophy, Duchenne; Myocardium; Spironolactone

2012
When the heart runs out of heartbeats: treatment options for refractory end-stage heart failure.
    Circulation, 2012, Jun-12, Volume: 125, Issue:23

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Carbazoles; Cardiotonic Agents; Carvedilol; Diuretics; Drug Therapy, Combination; Evidence-Based Medicine; Furosemide; Heart Failure; Heart Transplantation; Heart-Assist Devices; Humans; Lisinopril; Male; Middle Aged; Milrinone; Propanolamines; Severity of Illness Index; Spironolactone

2012
Commentary in support of a highly effective hypertension treatment algorithm.
    Journal of clinical hypertension (Greenwich, Conn.), 2013, Volume: 15, Issue:12

    Topics: Adult; Algorithms; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Combinations; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Lisinopril; Spironolactone; Treatment Outcome; United States

2013
Serum potassium in dual renin-angiotensin-aldosterone system blockade.
    Clinical journal of the American Society of Nephrology : CJASN, 2014, Volume: 9, Issue:2

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Diabetic Nephropathies; Diuretics; Female; Humans; Lisinopril; Losartan; Male; Potassium; Renin-Angiotensin System; Spironolactone

2014
Prednisolone attenuates improvement of cardiac and skeletal contractile function and histopathology by lisinopril and spironolactone in the mdx mouse model of Duchenne muscular dystrophy.
    PloS one, 2014, Volume: 9, Issue:2

    Topics: Animals; Cardiotonic Agents; Disease Models, Animal; Diuretics; Dystrophin; Female; Gene Expression; Glucocorticoids; Humans; Lisinopril; Losartan; Male; Mice; Mice, Inbred mdx; Muscle Contraction; Muscle Weakness; Muscle, Skeletal; Muscular Dystrophy, Animal; Muscular Dystrophy, Duchenne; Myocardium; Prednisolone; Spironolactone; Utrophin

2014
Mineralocorticoid receptors are present in skeletal muscle and represent a potential therapeutic target.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2015, Volume: 29, Issue:11

    Topics: Aldosterone; Animals; Cell Line; Humans; Lisinopril; Mice; Muscle Fibers, Skeletal; Muscle Proteins; Muscular Diseases; Receptors, Melanocortin; Spironolactone

2015
Similar efficacy from specific and non-specific mineralocorticoid receptor antagonist treatment of muscular dystrophy mice.
    Journal of neuromuscular diseases, 2016, Volume: 3, Issue:3

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Disease Models, Animal; Eplerenone; Gene Knockdown Techniques; Heart; Lisinopril; Male; Mice; Mice, Inbred mdx; Mineralocorticoid Receptor Antagonists; Muscle, Skeletal; Muscular Dystrophy, Animal; Myocardium; Spironolactone; Treatment Outcome; Utrophin

2016
Renin-angiotensin-aldosterone system inhibitors improve membrane stability and change gene-expression profiles in dystrophic skeletal muscles.
    American journal of physiology. Cell physiology, 2017, Feb-01, Volume: 312, Issue:2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Cell Membrane; Dose-Response Relationship, Drug; Gene Expression Regulation; Lisinopril; Male; Mice; Mice, Inbred C57BL; Mineralocorticoid Receptor Antagonists; Muscle Proteins; Muscular Dystrophies; Renin-Angiotensin System; Spironolactone; Treatment Outcome

2017
90-year-old man • dyspnea • lower extremity edema • limitations in daily activities • Dx?
    The Journal of family practice, 2020, Volume: 69, Issue:9

    Topics: Activities of Daily Living; Aged, 80 and over; Diagnosis, Differential; Diuretics; Dyspnea; Edema; Female; Heart Failure; Humans; Lisinopril; Lower Extremity; Metoprolol; Obesity; Spironolactone; Torsemide

2020
Homoarginine treatment of rats improves cardiac function and remodeling in response to pressure overload.
    Fundamental & clinical pharmacology, 2022, Volume: 36, Issue:6

    Topics: Animals; Blood Pressure; Heart Failure; Homoarginine; Hypertension; Lisinopril; Male; Myocardium; NG-Nitroarginine Methyl Ester; Rats; Rats, Wistar; Spironolactone; Ventricular Remodeling

2022