spironolactone has been researched along with ketoconazole in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (7.14) | 18.7374 |
| 1990's | 10 (35.71) | 18.2507 |
| 2000's | 7 (25.00) | 29.6817 |
| 2010's | 9 (32.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Huben, RP | 1 |
| Brun, HP; Caillaud, JM; Cordier, A; Leonard, JF; Melcion, C; Moronvalle, V | 1 |
| Fair, WR; Sogani, PC | 1 |
| Duckett, G; Root, AW; Sweetland, M; Zamanillo, J | 1 |
| Bernhardt, R; Denner, K; Doehmer, J; Schmalix, W; Vogel, R | 1 |
| Feuillan, PP | 1 |
| Cutler, GB; Laue, L | 1 |
| Bourguignon, JP; Kulin, HE | 1 |
| Allen, LV; Erickson, MA | 1 |
| Gökmen, O; Gülekli, B; Işik, AZ; Senöz, S | 1 |
| Shaw, JC | 1 |
| Bare, RL; Torti, FM | 1 |
| Ligtenberg, JJ; Meertens, JH; Monteban-Kooistra, WE; Oosterhuis, JK; Tulleken, JE; van den Berg, G; Zijlstra, JG | 1 |
| Billalabeitia, EG; Carmona-Bayonas, A; Díaz, MP; Gómez, FI; Saura, HP; Soler, IO; Tafalla, MS | 1 |
| Ioannides, D; Lazaridou, E | 1 |
| Hu, S; Infantino, D; Lubitz, S; Ohri, A; Sedhom, R | 1 |
| Peiró, I; Simó-Servat, A; Villabona, C | 1 |
5 review(s) available for spironolactone and ketoconazole
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Treatment of advanced prostatic cancer.
Topics: Adrenalectomy; Aminoglutethimide; Androgen Antagonists; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Combined Modality Therapy; Cyproterone; Cyproterone Acetate; Estrogens; Flutamide; Glucocorticoids; Humans; Ketoconazole; Male; Megestrol; Megestrol Acetate; Orchiectomy; Pituitary Hormone-Releasing Hormones; Prostatic Neoplasms; Spironolactone; Time Factors | 1987 |
Antiandrogen therapy in dermatology.
Topics: Adrenal Cortex Hormones; Androgen Antagonists; Cimetidine; Contraceptives, Oral; Cyproterone Acetate; Finasteride; Flutamide; Humans; Ketoconazole; Skin Diseases; Spironolactone | 1996 |
Endocrine therapy of prostate cancer.
Topics: 5-alpha Reductase Inhibitors; Adenocarcinoma; Aminoglutethimide; Androgen Antagonists; Antineoplastic Agents, Hormonal; Chemotherapy, Adjuvant; Clinical Trials as Topic; Combined Modality Therapy; Drug Therapy, Combination; Enzyme Inhibitors; Estrogens; Gonadotropin-Releasing Hormone; Humans; Ketoconazole; Male; Neoplasm Metastasis; Neoplasms, Hormone-Dependent; Orchiectomy; Prognosis; Prostatic Neoplasms; Receptors, LHRH; Spironolactone; Survival Analysis; Testosterone | 1998 |
Female pattern hair loss.
Topics: 5-alpha Reductase Inhibitors; Administration, Cutaneous; Alopecia; Androgen Antagonists; Androgen Receptor Antagonists; Antifungal Agents; Cyproterone Acetate; Dutasteride; Female; Finasteride; Flutamide; Hair; Humans; Ketoconazole; Minoxidil; Postmenopause; Spironolactone; Vasodilator Agents | 2015 |
3 trial(s) available for spironolactone and ketoconazole
| Article | Year |
|---|---|
Hormone therapy of prostatic bone metastases.
Topics: Actuarial Analysis; Androgen Antagonists; Bone Neoplasms; Combined Modality Therapy; Diethylstilbestrol; Estrogens; Flutamide; Gonadotropin-Releasing Hormone; Goserelin; Humans; Ketoconazole; Leuprolide; Male; Neoplasms, Hormone-Dependent; Orchiectomy; Prostatic Neoplasms; Remission Induction; Spironolactone; Survival Rate | 1992 |
Treatment of advanced prostatic cancer.
Topics: Adrenalectomy; Aminoglutethimide; Androgen Antagonists; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Combined Modality Therapy; Cyproterone; Cyproterone Acetate; Estrogens; Flutamide; Glucocorticoids; Humans; Ketoconazole; Male; Megestrol; Megestrol Acetate; Orchiectomy; Pituitary Hormone-Releasing Hormones; Prostatic Neoplasms; Spironolactone; Time Factors | 1987 |
Comparison of four different treatment regimes in hirsutism related to polycystic ovary syndrome.
Topics: Adolescent; Adult; Androgen Antagonists; Cholesterol, HDL; Cholesterol, LDL; Cohort Studies; Contraceptives, Oral, Combined; Cyproterone; Dehydroepiandrosterone; Female; Hirsutism; Humans; Ketoconazole; Luteinizing Hormone; Mineralocorticoid Receptor Antagonists; Polycystic Ovary Syndrome; Spironolactone; Testosterone | 1996 |
21 other study(ies) available for spironolactone and ketoconazole
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Pig Leydig cell culture: a useful in vitro test for evaluating the testicular toxicity of compounds.
Topics: Aminoglutethimide; Animals; Cell Survival; Cells, Cultured; Chlorpromazine; Chorionic Gonadotropin; Cyclic AMP; Cycloheximide; Ketoconazole; Kinetics; Leydig Cells; Male; Progesterone; Spironolactone; Steroids; Swine; Testis; Testosterone; Time Factors; Toxicology | 1991 |
Gonadotropin-independent isosexual precocity in a boy with tuberous sclerosis: effect of ketoconazole.
Topics: Age Determination by Skeleton; Child, Preschool; Follicle Stimulating Hormone; Gonadotropins, Pituitary; Humans; Ketoconazole; Luteinizing Hormone; Male; Pituitary Hormone-Releasing Hormones; Puberty, Precocious; Spironolactone; Testosterone; Tuberous Sclerosis | 1986 |
Cloning and stable expression of the human mitochondrial cytochrome P45011B1 cDNA in V79 Chinese hamster cells and their application for testing of potential inhibitors.
Topics: Adrenal Glands; Animals; Base Sequence; Cell Line; Cloning, Molecular; Clotrimazole; Cricetinae; Cricetulus; DNA Primers; DNA, Complementary; Fluconazole; Gene Expression; Hydrocortisone; Hydroxylation; Ketoconazole; Kinetics; Metyrapone; Miconazole; Mitochondria; Molecular Sequence Data; Polymerase Chain Reaction; Recombinant Proteins; Restriction Mapping; Spironolactone; Steroid 11-beta-Hydroxylase; Transfection | 1995 |
McCune-Albright syndrome.
Topics: Adolescent; Calcitriol; Diagnosis, Differential; Female; Fibrous Dysplasia, Polyostotic; Humans; Ketoconazole; Leuprolide; Male; Medroxyprogesterone Acetate; Octreotide; Ovariectomy; Propylthiouracil; Puberty, Precocious; Spironolactone; Testolactone; Thyroid Diseases | 1994 |
Familial male precocious puberty.
Topics: Child; Gonadotropin-Releasing Hormone; Humans; Ketoconazole; Male; Puberty, Precocious; Spironolactone; Testolactone | 1994 |
True or central precocious puberty.
Topics: Cyproterone Acetate; Female; Gonadotropin-Releasing Hormone; Humans; Ketoconazole; Male; Medroxyprogesterone Acetate; Puberty, Precocious; Spironolactone; Testolactone | 1994 |
Stability of ketoconazole, metolazone, metronidazole, procainamide hydrochloride, and spironolactone in extemporaneously compounded oral liquids.
Topics: Administration, Oral; Anti-Arrhythmia Agents; Antifungal Agents; Antihypertensive Agents; Antitrichomonal Agents; Chromatography, High Pressure Liquid; Diuretics; Dosage Forms; Drug Compounding; Drug Stability; Humans; Hydrogen-Ion Concentration; Ketoconazole; Metolazone; Metronidazole; Pharmaceutical Vehicles; Procainamide; Solubility; Spironolactone; Suspensions | 1996 |
Life-threatening Pneumocystis jiroveci pneumonia following treatment of severe Cushing's syndrome.
Topics: Cushing Syndrome; Disease Progression; Fatal Outcome; Female; Humans; Ketoconazole; Middle Aged; Mifepristone; Opportunistic Infections; Pneumocystis carinii; Pneumonia, Pneumocystis; Risk Factors; Spironolactone | 2007 |
Tailored hormonal therapy in secretory adrenocortical cancer.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Carcinoma; Aged; Aldosterone; Alkalosis; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents; Antifungal Agents; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Captopril; Cisplatin; Diarrhea; Doxorubicin; Etoposide; Female; Heart Failure; Humans; Hydrocortisone; Hyperaldosteronism; Hypertension; Hypokalemia; Ketoconazole; Mineralocorticoid Receptor Antagonists; Mitotane; Neoplasm Recurrence, Local; Potassium; Rhabdomyolysis; Spironolactone; Tachycardia | 2007 |
Symptomatic Cushing's syndrome and hyperandrogenemia in a steroid cell ovarian neoplasm: a case report.
Topics: Aged; Antineoplastic Agents, Hormonal; Cushing Syndrome; Disease Progression; Fatal Outcome; Female; Humans; Hyperandrogenism; Ketoconazole; Mitotane; Ovarian Neoplasms; Practice Guidelines as Topic; Rare Diseases; Sex Cord-Gonadal Stromal Tumors; Spironolactone | 2016 |
Corticotropin secreting pancreatic neuroendocrine tumour, a therapeutic management challenge. A presentation of 2 cases.
Topics: ACTH Syndrome, Ectopic; Adrenocorticotropic Hormone; Chromogranins; Combined Modality Therapy; Embolization, Therapeutic; Everolimus; Female; Fludrocortisone; Humans; Hydrocortisone; Ketoconazole; Liver Neoplasms; Male; Middle Aged; Pancreatectomy; Pancreatic Neoplasms; Peptides, Cyclic; Phenylurea Compounds; Quinolines; Somatostatin; Spironolactone; Splenectomy; Sunitinib | 2019 |