Compounds > spironolactone
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spironolactone and hydroxyflutamide

spironolactone has been researched along with hydroxyflutamide in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bydal, P; Labrie, F; Luu-The, V; Poirier, D1
Bellavance, E; Luu-The, V; Poirier, D1
Arias, DA; Barbieri, LR; Berrodin, TJ; Bigelis, R; Chang, LP; Luckman, SW; McDonald, LA; Roll, DM; Singh, MP; Yudt, MR1
Begin, DJ; Labrie, F; Luthy, IA1

Other Studies

4 other study(ies) available for spironolactone and hydroxyflutamide

ArticleYear
Steroidal lactones as inhibitors of 17beta-hydroxysteroid dehydrogenase type 5: chemical synthesis, enzyme inhibitory activity, and assessment of estrogenic and androgenic activities.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:2

    Topics: 17-Hydroxysteroid Dehydrogenases; Cell Line; Cell Proliferation; Enzyme Inhibitors; Humans; Lactones; Male; Prostatic Diseases; Receptors, Androgen; Receptors, Estrogen; Receptors, Glucocorticoid; Receptors, Progesterone; Steroids; Structure-Activity Relationship

2009
Potent and selective steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 7, an enzyme that catalyzes the reduction of the key hormones estrone and dihydrotestosterone.
    Journal of medicinal chemistry, 2009, Dec-10, Volume: 52, Issue:23

    Topics: 17-Hydroxysteroid Dehydrogenases; Androstane-3,17-diol; Androstanes; Biocatalysis; Cell Line; Dihydrotestosterone; Enzyme Inhibitors; Estradiol; Estrone; Humans; Inhibitory Concentration 50; Oxidation-Reduction; Substrate Specificity

2009
The lecanindoles, nonsteroidal progestins from the terrestrial fungus Verticillium lecanii 6144.
    Journal of natural products, 2009, Volume: 72, Issue:11

    Topics: Animals; Chlorocebus aethiops; Female; Humans; Hypocreales; Indoles; Luciferases; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Progestins; Receptors, Progesterone; Sesquiterpenes

2009
Androgenic activity of synthetic progestins and spironolactone in androgen-sensitive mouse mammary carcinoma (Shionogi) cells in culture.
    Journal of steroid biochemistry, 1988, Volume: 31, Issue:5

    Topics: Androgens; Animals; Cell Division; Chlormadinone Acetate; Dihydrotestosterone; Flutamide; Male; Mammary Neoplasms, Experimental; Medroxyprogesterone; Medroxyprogesterone Acetate; Megestrol; Mice; Progestins; Spironolactone; Tumor Cells, Cultured

1988