spironolactone has been researched along with hydrochlorothiazide in 262 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 204 (77.86) | 18.7374 |
| 1990's | 8 (3.05) | 18.2507 |
| 2000's | 22 (8.40) | 29.6817 |
| 2010's | 23 (8.78) | 24.3611 |
| 2020's | 5 (1.91) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Abellán Guillén, A; Cordeiro, MN; Garrido Escudero, A; Morales Helguera, A; Pérez-Garrido, A | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Overlack, O; Stumpe, KO | 1 |
| Chakravarti, RN; Gulati, OP; Sharma, PL | 1 |
| Kim, KS; Miyamori, I; Miyamoto, M; Morimoto, S; Takeda, R; Uchida, K | 1 |
| Ames, RP; Hill, P | 1 |
| Dalakos, TG; Pinals, RS; Streeten, DH | 1 |
| Ferguson, RK; Rovner, DR; Turek, DM | 1 |
| Brooks, CS; Johnson, CA; Kotchen, JM; Kotchen, TA | 1 |
| Levy, B | 1 |
| Nash, DT | 1 |
| Abignente, F; Aliperta, A; Caldarelli, G; Castagnolo, B; De Colibus, V; Napolitano, L | 1 |
| Friedman, A; Johnston, CI; Suthers, MB; Walter, NM | 1 |
| Schrijver, G; Weinberger, MH | 1 |
| Karim, A | 1 |
| Eisalo, A; Kohvakka, A; Manninen, V | 1 |
| Hofmann, LM; Pedrera, HA; Suleymamov, OD | 1 |
| Roeltgen, D | 1 |
| Fairchild, C; Gomez-Sanchez, C; Holland, OB; Kaplan, NM | 1 |
| Mauro, B; Savagnone, E | 1 |
| Hull, DH; McAfoose, DA; Triebwasser, JH; Wolthuis, RA | 1 |
| Alhenc-Gelas, F; Corvol, P; Ducrocq, MB; Menard, J; Plouin, PF | 1 |
| Jones, W; Wong, R | 1 |
| Ebel, H; Klaus, D; Lübke, H; Witzgall, H; Zehner, J | 1 |
| Benvenuti, C; Sanguigni, D | 1 |
| Barrett, JC; Eggena, P; Sambhi, MP; Thananopavarn, C; Tuck, M; Wiedeman, CE | 1 |
| Hofmann, LM; Pedrera, HA; Suleymanov, OD; Weier, RM | 1 |
| Savenkov, MP | 1 |
| Anderson, GH; Dalakos, TG; Elias, A; Streeten, DH; Tomycz, N | 1 |
| Burkett, LL; Hamilton, HE; Schwertner, H; Skrdlant, H; Wallace, JE | 1 |
| Grim, CE | 1 |
| Cuparencu, B; Florescu, P; Holan, T; Petrescu, L; Racovita, L | 1 |
| Chao, AY; Karim, A; Mattes, K; Nicholova, B; Sanvordeker, DR; Zagarella, J | 1 |
| Gunnells, JC; McGuffin, WL | 1 |
| Bobkova, VI; Kartitskií, VS; Lapkes, TG; Mazurova, SV | 1 |
| Evsikov, EM; Kharchenko, VI; Savenkov, PM; Sidorenko, BA | 1 |
| Braun, B; Klaus, D; Klump, F; Lemke, R; Zehner, J; Zöfel, P | 1 |
| Cummings, JR; Gussin, RZ; Ronsberg, MA; Stokey, EH | 1 |
| Wilson, CS; Wong, R | 2 |
| Leumann, EP; Nussberger, J; Vetter, W | 1 |
| Garcá Puig, J; Gil, A; Herrero, E; Lavilla, P; Mateos, F; Miranda, ME | 1 |
| Bachman, WJ; Stewart, JT | 1 |
| Lauler, DP | 1 |
| Bolli, P; Brouwer, RM; Bühler, FR; Conen, D; Erné, P; Kiowski, W | 1 |
| Brunkhorst, R; Koch, K; Kühn, K; Schmidt, FW; Wrenger, E | 1 |
| Albersheim, SG; Rotschild, A; Sharma, AK; Sheps, SB; Smyth, JA; Solimano, AJ; Wood, BJ | 1 |
| Basile, AS; Lueddens, HW; Skolnick, P | 1 |
| Brest, AN | 1 |
| Storm, W | 1 |
| Blalock, WA; DonLevy, S; Engelhardt, B; Hazinski, TA; Rush, M | 1 |
| Charru, A; Chatellier, G; Corvol, P; Degoulet, P; Jeunemaitre, X; Julien, J; Ménard, J; Plouin, PF | 1 |
| Akbar, FA; Cranfield, FR; Markanday, S; Shelton, JR; Walters, EG | 1 |
| Atkinson, SA; McGee, C; Shah, JK; Steele, BT | 1 |
| Velázquez, H; Wright, FS | 1 |
| Krzesinski, JM; Rorive, G | 1 |
| Houston, MC; Johnston, PE | 1 |
| Conradi, EC; Cowart, TD; Hughes, GS | 1 |
| Greenberg, A | 1 |
| Dralle, H; Stimpel, M; von zur Mühlen, A | 1 |
| Cobb, SD; Miller, SA; Petrulis, AS; Vertes, V | 1 |
| Garcia-Alves, M; Macieira-Coelho, E; Reis-Valle, A | 1 |
| Lochaya, S; Suvachittanont, O; Triyanond, K | 1 |
| el Kousy, NM; Moussa, BA | 1 |
| Ehrlich, E; Mauersberger, H; Rangoonwala, B | 1 |
| Breckenridge, AM; Dollery, CT; George, CF | 1 |
| Black, JA; Challacombe, DN; Ockenden, BG | 1 |
| Gaunt, R; Gisoldi, E; Herkner, J; Howie, N; Renzi, AA | 1 |
| Kaess, H; Losert, W; Senft, G; Sitt, R | 1 |
| Erbler, HC | 2 |
| Colton, T; Lubbe, WF; Winer, BM | 1 |
| Reimold, EW | 1 |
| Spark, RF | 1 |
| Fukuchi, S; Nakajima, K; Takenouchi, T | 1 |
| Ilett, KF; Lockett, MF | 1 |
| Ibsen, H | 1 |
| Carey, RM; Hook, EW; Wooster, LD | 1 |
| Fukuchi, S; Nakajima, K; Nishisato, K; Takenouchi, T | 1 |
| Ambrosioni, E; Costa, FV; Magnani, B | 1 |
| Sanna, GP | 1 |
| Amery, AK; Joossens, JV; Parijs, J; Van der Linden, L; Verstreken, G | 1 |
| Leemhuis, MP; Struyvenberg, A | 1 |
| Jones, J | 1 |
| Douglas, JG; Hollifield, JW; Liddle, GW | 1 |
| O'Hare, CM; Regan, RM; Spark, RF | 1 |
| Dalla Volta, S; Miraglia, G; Nava, A | 1 |
| Distler, A | 1 |
| Acchiardo, S; Dustan, HP; Tarazi, RC | 1 |
| Ravera, M; Spaziante, B | 1 |
| Kim, KE; Onesti, G; Swartz, C | 1 |
| Finnerty, FA | 1 |
| Bravo, EL; Dustan, HP; Tarazi, RC | 3 |
| Fishback, DB | 1 |
| Murphy, AV | 1 |
| Ina, K; Suzuki, Y; Yamagami, I | 1 |
| Calvert, GD; Ibbertson, HK; Sridhar, CB | 1 |
| Hardisty, R; Wong, R | 1 |
| Distler, A; Keim, HJ; Philipp, T; Philippi, A; Walter, U; Werner, E | 1 |
| Gulati, OD; Munshi, CP; Sawkar, LA; Vaidya, PM | 1 |
| Froment, A; Froment, R; Zech, P | 1 |
| Macoul, KL; Paris, GL | 1 |
| Ikeda, T | 1 |
| Selchau, M | 1 |
| Marosi, J; Radó, JP; Takó, J | 1 |
| Garcia, HA; Hofmann, LM; Krupnick, MI | 1 |
| Kojima, K; Shinoda, M; Suzuki, Y; Yamagami, I | 1 |
| Meyer, P; Milliez, P | 1 |
| Adlin, EV; Channick, BJ; Marks, AD | 1 |
| Kornfeld, P; Mendlowitz, M; Roboz, J; Styan, GP; Weigl, A; Wolf, RL | 1 |
| Dettli, L; Spring, P | 1 |
| Ogilvie, RI; Ruedy, J | 1 |
| Goto, K; Katsushima, I; Maebashi, M; Miura, K; Yoshinaga, K | 1 |
| Hofmann, LM; Sagartz, JW | 1 |
| Reynolds, TB; Yamada, S | 1 |
| Flick, DF; O'Dell, RG | 1 |
| Matveev, LN; Vinogradov, AV | 1 |
| Doll, R; Langman, MJ; Shawdon, HH | 1 |
| Diner, WC | 1 |
| Yasui, H | 1 |
| Anghel, R; Demirian, H; Georgescu, D; Ionitã, C; Păunescu-Podanu, A; Rubingher, L; Tarachiu, A | 1 |
| Portmann, B; Robert, M | 1 |
| Eytel, CS; Schneider, PJ | 1 |
| Pomerantz, HZ | 1 |
| Sala, G | 1 |
| Polli, E | 1 |
| Lieberman, FL; Reynolds, TB | 1 |
| Cheng, CS; Fu, FY; Liu, H; Lu, ST; T'ang, MK | 1 |
| Glitzer, MS; Steelman, SL | 1 |
| Andreucci, VE; Carrara, GC | 1 |
| Hofmann, LM | 2 |
| Christensen, M; Galskov, A | 1 |
| Foy, JM | 1 |
| Gagnon, O; Gertman, PM; Iber, FL | 1 |
| Gwinup, G; Steinberg, T | 1 |
| Bufalari, A; Meloni, G | 1 |
| Favre, L; Glasson, P; Riondel, A; Vallotton, MB | 1 |
| Descos, L; Durbec, JP; Fermanian, J; Fombonne, E; Gauthier, A; Levy, VG; Michel, H; Quinton, A; Rueff, B | 1 |
| Cape, RD; Finnegan, TP; Spence, JD | 1 |
| Beermann, B | 1 |
| Moyer, JH | 1 |
| Corea, L; Fariello, R; Innocenti, PF; Porcellati, C; Roncati, G | 1 |
| Matzkies, F; Webs, B | 1 |
| Ames, RP; Peacock, PB | 1 |
| Cocco, F; Dessì-Fulgheri, P; Fiori, C; Glorioso, N; Leoni, C; Madeddu, P; Rappelli, A; Sanna, G | 1 |
| Rahn, KH | 1 |
| Dyckner, T; Wester, PO; Widman, L | 1 |
| Bader, PI; Campbell, NM; Conn, PS; Creason, PL; Lakes, MK; Merkle, GW; Townsend, DW | 1 |
| Leya, A; Rhomberg, F | 1 |
| Halawa, B | 1 |
| Hansson, L; Lavenius, B | 1 |
| Slosberg, PS | 1 |
| Weishar, C | 1 |
| Hitzenberger, G; Horwatitsch, H; Rameis, H | 1 |
| Brennan, AP; Carlson, RW; Puri, VK; Schaeffer, RC; Weil, MH | 1 |
| Cozzolino, S; La Rotonda, MI; Schettino, O | 1 |
| Clearfield, H | 1 |
| Rybina, LV; Zhurova, MV | 1 |
| Bäcker, A; Düsing, R; Eden, J; Glänzer, K; Kipnowski, J; Kramer, HJ; Krück, F; Prior, W; Stinnesbeck, B | 1 |
| Davies, DL; Forrest, G; McInnes, GT; Murdoch, DL | 1 |
| Allen, LV; Erickson, MA | 1 |
| Hammer, HF; Krejs, GJ; Stepan, VM | 1 |
| Constable, PD; Foreman, JH; Morin, DE; Thurmon, JC; Walker, PG | 1 |
| Constable, PD; Drackley, JK; Foreman, JH; Morin, DE; Thurmon, JC; Walker, PG | 1 |
| Brown, NJ; Kumar, S; Sawathiparnich, P; Vaughan, DE | 1 |
| SETTEL, E | 2 |
| FARRELLY, RO; HOWIE, RN; NORTH, JD | 1 |
| GARCIA, H; GAZMURI, R; KATZ, E; KATZ, R; VELASCO, M | 1 |
| CATTAN, R; VESIN, P | 1 |
| ECKLUND, RE; GANTT, CL | 1 |
| BAYLEY, TA; FORBATH, PG; HIGGINS, HP; WILSON, JK | 1 |
| BOUSQUET, WF; CHRISTIAN, JE; RUPE, BD | 1 |
| DUBIN, A; SISON, A; STEIGMANN, F | 1 |
| KHOKHANI, RC; SHAH, PN | 1 |
| PENATI, MR; SALA, G | 1 |
| HORKY, K; KUECHEL, O | 1 |
| CARPENTER, CJ; MITRA, P | 1 |
| ALVAREZ, A; LEW, V; PEREZ, V; PICCALUGA, A; RATTI, J | 1 |
| BETZIEN, G; BRANCHRZ, H; LAAS, H | 1 |
| COMOLI, G; GHIRINGHELLI, L; MADULI, S | 1 |
| CENANI, A; FRIEDERISZICK, FK | 1 |
| BREST, AH; MOYER, JH; RAMIREZ-MUXO, O; SELLER, RH; SWARTZ, CD | 1 |
| DUNLOP, D | 1 |
| CASTELLUCCIO, A; D AMICO, G; POLLI, E; SALA, G; VITERTARI, L | 1 |
| ALVAREZ, S; DUBIN, A; STEIGMANN, F; TRIANTAFILIDES, T | 1 |
| LIEBERMAN, ME | 1 |
| ANIBALDI, A; BOSCHERINI, B; PAIELLA, R | 1 |
| ANIBALDI, A; BOSCHERINI, B; PATANE, E; PEDULLA, T | 1 |
| ARMASCRUZ, R; GOMEZ, R; MARDONES, J; PLAZADELOSREYES, M | 1 |
| BAGROS, P | 1 |
| BOEHM, P; IRMSCHER, K; ZIMMERMANN, H | 1 |
| CASCIO, G; PALAZZOADRIANO, M | 1 |
| KENNEDY, BJ | 1 |
| KAGAWA, CM | 1 |
| BORRELLI, PL; CAIRELLA, M; DEMARTIIS, M | 1 |
| ROMANI, JD | 1 |
| FORTI, D; LONGO, T | 1 |
| LAUFER, ST; MAHABIR, RN | 1 |
| STOKES, W | 1 |
| PEARSON, CM | 1 |
| ANTOGNETTI, R; BARATTA, C; MARANGONI, R; MELLONI, GF; MERLO, L | 1 |
| EAKIN, EL; FLETCHER, CB; ROTHMAN, PE | 1 |
| FANTATO, S | 1 |
| ARSTILA, A; MAEKINEN, E; VANHA-PERTTULA, T | 1 |
| GABUZDA, GJ; GINSBERG, DJ; SAAD, A | 1 |
| BERNSTEIN, A; CREWS, A; ODZE, M; SIMON, F | 1 |
| LATTA, H; LITMAN, N; SMITH, FG | 1 |
| BRUNNER, E; RISSEL, E | 1 |
| DRILL, VA; KAGAWA, CM | 1 |
| Burns, D; Kleiman, J; Krause, S; Phillips, RA; Pitt, B; Reichek, N; Roniker, B; Willenbrock, R; Williams, GH; Zannad, F | 1 |
| Dinç, E; Ustündağ, O | 1 |
| Aboul-Enein, HY; Baleanu, D; Dinç, E; Ustündağ, O | 1 |
| Albornoz, F; Brown, NJ; Byrne, DW; Ma, J; Vaughan, DE; Yu, C | 1 |
| Bhattacharya, SK; Chhokar, VS; Runyan, AL; Runyan, JW; Sun, Y; Weber, KT | 1 |
| Kaşifoğlu, T; Yalçin, AU | 1 |
| Buckingham, R; Karalliedde, J; Lorand, D; Starkie, M; Stewart, M; Viberti, G | 1 |
| Adler, GK; Feldman, K; Gerhard-Herman, MD; Joffe, HV; Kwong, RY; Rice, C | 1 |
| Ji, Z; Liu, C; Liu, G; Liu, K; Zhen, Y; Zhou, C | 1 |
| Aleksandrowicz, E; Larczyński, W; Lysiak-Szydlowska, W; Renke, M; Rutkowski, B; Rutkowski, P; Tylicki, L | 1 |
| Amann, K; Hartner, A; Hilgers, KF; Klanke, B; Melk, A; Steinbach, MP; Westhoff, JH | 1 |
| Cordasic, N; Hartner, A; Hilgers, KF; Klanke, B; Schmieder, RE; Veelken, R | 1 |
| Knap, N; Larczynski, W; Neuwelt, A; Renke, M; Rutkowski, B; Rutkowski, P; Tylicki, L; Wozniak, M | 1 |
| CAO, ZX; DU, X; HOU, GS; LI, DX; LIU, FS; QI, RP; SONG, SM; WANG, GL; WANG, LG; WU, SL; XING, AJ; YU, Q | 1 |
| Castro, MM; Ceron, CS; Fontana, V; Gerlach, RF; Montenegro, MF; Rizzi, E; Salgado, MC; Tanus-Santos, JE | 1 |
| Supiano, MA; Wray, DW | 1 |
| Abdelkawy, M; Abdelwahab, NS; Hegazy, MA; Metwaly, FH | 2 |
| Kithas, PA; Supiano, MA | 1 |
| Ashek, A; Bailey, MA; Bellamy, CO; Flatman, PW; Harmar, AJ; Kenyon, CJ; Menzies, RI; Mullins, JJ; Mullins, LJ | 1 |
| Behradmanesh, MS; Karami Horestani, M; Kheiri, S; Momeni, A | 1 |
| Gromadziński, L; Januszko-Giergielewicz, B; Kubiak, M; Pruszczyk, P | 1 |
| Handler, J | 1 |
| Gao, Y; Jia, L; Li, M; Li, X; Zhao, M | 1 |
| Aliaga, S; Chantala, K; Clark, RH; Herring, AH; Hornik, CP; Hughes, R; Laughon, MM; Smith, PB | 1 |
| O'Brien, E | 1 |
| Adler, GK; Baimas-George, M; Di Carli, MF; Foster, C; Garg, R; Hurwitz, S; Jerosch-Herold, M; Kwong, RY; Rao, AD; Shah, RV | 1 |
| Briukhovetskiĭ, AG; Medvedev, IN | 1 |
| Dorrance, AM; Jackson, WF; Pires, PW | 1 |
| Argyropoulou, MI; Christopoulou, F; Elisaf, M; Kosta, P; Rizos, EC | 1 |
| Dave, C; Hwang, AY; Smith, SM | 1 |
| Dai, S; Liao, H; Liu, L; Liu, Y; Xiao, C | 1 |
| Aboul-Enein, HY; Ali, I; ALOthman, ZA; Alsheetan, KM | 1 |
| Bušić, Ž; Čulić, V; Jurić Paić, M; Velat, I | 1 |
| Kalantarian, S; Klein, L; Scheinman, MM; Vittinghoff, E | 1 |
| Bao, M; Li, J; Song, Y; Wu, S | 1 |
| Andjic, M; Bolevich, S; Dragasevic, N; Draginic, N; Jakovljevic, V; Mihajlovic, K; Nikolic Turnic, T; Savic, M; Zdravkovic, N; Zivkovic, V | 1 |
15 review(s) available for spironolactone and hydrochlorothiazide
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Spironolactone: disposition, metabolism, pharmacodynamics, and bioavailability.
Topics: Animals; Biological Availability; Biotransformation; Canrenoic Acid; Drug Combinations; Erythrocytes; Food; Half-Life; Humans; Hydrochlorothiazide; Kinetics; Milk, Human; Protein Binding; Species Specificity; Spironolactone; Tissue Distribution | 1978 |
Low renin hypertension.
Topics: Adult; Age Factors; Diagnosis, Differential; Female; Humans; Hydrochlorothiazide; Hyperaldosteronism; Hypertension; Hypertension, Renal; Male; Mineralocorticoids; Prognosis; Renin; Spironolactone; Thiazines | 1975 |
Spironolactone in the treatment of hypertension: a review.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Calcium Channel Blockers; Captopril; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Renin-Angiotensin System; Spironolactone | 1986 |
Control by drugs of renal potassium handling.
Topics: Acetazolamide; Amiloride; Animals; Diuretics; Furosemide; Humans; Hydrochlorothiazide; Indans; Kidney; Kidney Tubules; Potassium; Spironolactone | 1986 |
[Properties and indications of potassium-sparing diuretics].
Topics: Amiloride; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hyperaldosteronism; Hypertension; Hypokalemia; Sodium Chloride Symporter Inhibitors; Spironolactone; Triamterene | 1986 |
Essential hypertension: new insights and controversies in treatment with diuretics.
Topics: Amiloride; Antihypertensive Agents; Blood Pressure; Coronary Disease; Diuretics; Dose-Response Relationship, Drug; Drug Combinations; Furosemide; Humans; Hydrochlorothiazide; Hyperkalemia; Hypertension; Lipoproteins, LDL; Magnesium; Potassium; Potassium Chloride; Sodium Chloride Symporter Inhibitors; Spironolactone; Triamterene; Triglycerides | 1986 |
Significance of hypokalaemia due to diuretics.
Topics: Amiloride; Arrhythmias, Cardiac; Chlorothiazide; Diuretics; Ethacrynic Acid; Extracellular Space; Furosemide; Hepatic Encephalopathy; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Kidney Tubules; Liver Cirrhosis; Natriuresis; Potassium; Potassium Chloride; Spironolactone; Triamterene | 1973 |
Renin and hypertension: a review article.
Topics: Aldosterone; Humans; Hydrochlorothiazide; Hypertension; Juxtaglomerular Apparatus; Kidney Diseases; Renin; Spironolactone; Sympatholytics | 1973 |
[Hypertension--diuretics as antihypertensive agents].
Topics: Aged; Antihypertensive Agents; Arthritis; Benzothiadiazines; Blood Pressure; Chlorothiazide; Chlorthalidone; Diabetes Mellitus; Diuretics; Ethacrynic Acid; Furosemide; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Male; Middle Aged; Photosensitivity Disorders; Spironolactone; Triamterene | 1970 |
[Diuretics. 47].
Topics: Antihypertensive Agents; Bendroflumethiazide; Chlorothiazide; Chlorthalidone; Clopamide; Dichlorphenamide; Diuretics; Edema; Ethacrynic Acid; Furosemide; Glaucoma; Humans; Hydrochlorothiazide; Hydroflumethiazide; Metyrapone; Respiratory Insufficiency; Spironolactone; Sulfonamides; Triamterene | 1970 |
Aspects on pharmacokinetics of some diuretics.
Topics: Amiloride; Bendroflumethiazide; Bumetanide; Chlorthalidone; Diuretics; Furosemide; Humans; Hydrochlorothiazide; Kinetics; Sodium Chloride Symporter Inhibitors; Spironolactone | 1984 |
Drug systems approach to hypertension.
Topics: Captopril; Clonidine; Drug Combinations; Drug Therapy, Combination; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Hypertension, Malignant; Methyldopa; Patient Compliance; Prazosin; Proteinuria; Renin-Angiotensin System; Reserpine; Spironolactone | 1984 |
[Treatment of arterial hypertension in elderly patients].
Topics: Age Factors; Aged; Antihypertensive Agents; Chlorpromazine; Diazoxide; Dihydralazine; Drug Therapy, Combination; Furosemide; Humans; Hydrochlorothiazide; Hypertension; Methyldopa; Middle Aged; Spironolactone | 1981 |
[MECHANISM OF ACTION AND CLINICAL USE OF DIURETICS].
Topics: Bendroflumethiazide; Benzothiadiazines; Chlorothiazide; Chlorthalidone; Diuretics; Hydrochlorothiazide; Hydroflumethiazide; Kidney; Kidney Diseases; Mineralocorticoid Receptor Antagonists; Organomercury Compounds; Pharmacology; Physiology; Spironolactone | 1963 |
59 trial(s) available for spironolactone and hydrochlorothiazide
| Article | Year |
|---|---|
Diuretics, beta-blockers or both as treatment for essential hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Blood Pressure; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pindolol; Propanolamines; Propranolol; Renin; Saralasin; Spironolactone | 1979 |
Spironolactone and hydrochlorothiazide in normal-renin and low-renin essential hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Clinical Trials as Topic; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Radioimmunoassay; Renin; Spironolactone | 1977 |
Diuretic therapies in low renin and normal renin essential hypertension.
Topics: Adult; Blood Pressure; Body Weight; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Female; Furosemide; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Renin; Spironolactone; Uric Acid | 1977 |
The efficacy and safety of furosemide and a combination of spironolactone and hydrochlorothiazide in congestive heart failure.
Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Drug Evaluation; Electrolytes; Female; Furosemide; Heart Failure; Humans; Hydrochlorothiazide; Male; Middle Aged; Spironolactone; Time Factors | 1977 |
Antihypertensive effect and serum potassium homeostasis: comparison of hydrochlorothiazide and spironolactone alone and in combination.
Topics: Adult; Aged; Blood Urea Nitrogen; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Gynecomastia; Homeostasis; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Spironolactone | 1977 |
[Clinical evaluation of the use of diuretics in the ascitic phase of hepatic cirrhosis].
Topics: Acute Disease; Adult; Aged; Amiloride; Ascites; Clinical Trials as Topic; Diuretics; Drug Evaluation; Drug Therapy, Combination; Female; Furosemide; Humans; Hydrochlorothiazide; Liver Cirrhosis; Male; Middle Aged; Spironolactone; Triamterene | 1977 |
A comparison between spironolactone and hydrochlorothiazide with and without alpha-methyldopa in the treatment of hypertension.
Topics: Adult; Angiotensin II; Blood Pressure; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Renin; Spironolactone | 1978 |
Hydrochlorothiazide and spironolactone in hypertension.
Topics: Adult; Aldosterone; Blood Glucose; Blood Pressure; Blood Urea Nitrogen; Clinical Trials as Topic; Creatinine; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Renin; Spironolactone; Uric Acid | 1979 |
Maintenance of potassium balance during diuretic therapy.
Topics: Adult; Aged; Amiloride; Clinical Trials as Topic; Drug Combinations; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Male; Middle Aged; Placebos; Potassium; Potassium Chloride; Pyrazines; Spironolactone; Triamterene | 1979 |
Role of renin classification for diuretic treatment of black hypertensive patients.
Topics: Adult; Aged; Black or African American; Blood Pressure; Female; Furosemide; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Renin; Spironolactone | 1979 |
[Treatment of essential hypertension with a combination of propranolol, spironolactone-thiabutazide and dihydralazine (author's transl)].
Topics: Anxiety; Bradycardia; Dihydralazine; Drug Therapy, Combination; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Paresthesia; Potassium; Propranolol; Renin; Spironolactone | 1978 |
Hydrochlorothiazide versus spironolactone: long-term metabolic modifications in patients with essential hypertension.
Topics: Adult; Aged; Blood Pressure; Cholesterol; Diuretics; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Lipids; Male; Middle Aged; Potassium; Sodium Chloride Symporter Inhibitors; Spironolactone; Time Factors; Uric Acid | 1991 |
Antihypertensive treatment using calcium antagonists in combination with captopril rather than diuretics.
Topics: Adult; Aged; Amiloride; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Captopril; Diuretics; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Proline; Renin; Renin-Angiotensin System; Spironolactone; Verapamil | 1985 |
Randomized, double-blind, controlled trial of long-term diuretic therapy for bronchopulmonary dysplasia.
Topics: Bronchopulmonary Dysplasia; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Infant; Infant, Newborn; Length of Stay; Male; Respiration, Artificial; Respiratory Function Tests; Spironolactone | 1989 |
Effect of spironolactone-hydrochlorothiazide on lung function in infants with chronic bronchopulmonary dysplasia.
Topics: Bronchopulmonary Dysplasia; Drug Combinations; Hemoglobins; Humans; Hydrochlorothiazide; Infant; Infant, Newborn; Lung; Respiratory Function Tests; Spironolactone; Urine | 1989 |
A comparative study of Spiroprop and Moducren in the treatment of mild to moderate hypertension in general practice.
Topics: Adolescent; Amiloride; Antihypertensive Agents; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Propranolol; Spironolactone; Timolol | 1988 |
Step 1 1/2 therapy for the treatment of hypertension.
Topics: Antihypertensive Agents; Clinical Trials as Topic; Diuretics; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Metolazone; Middle Aged; Potassium; Spironolactone | 1985 |
Antihypertensive and hypokalemic effects of isobutyl hydrochlorothiazide alone and in combination with spironolactone.
Topics: Adult; Blood Pressure; Clinical Trials as Topic; Diuretics; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Random Allocation; Sodium Chloride Symporter Inhibitors; Spironolactone | 1985 |
[Comparative study of 2 diuretic-containing combination preparations in patients with edematous heart failure].
Topics: Aged; Diuretics; Drug Combinations; Edema, Cardiac; Female; Furosemide; Heart Failure; Humans; Hydrochlorothiazide; Liver Function Tests; Male; Middle Aged; Potassium; Sodium Chloride Symporter Inhibitors; Spironolactone | 1985 |
Comparison of the potassium- retaining effects of amiloride and spironolactone in hypertensive patients with thiazide-induced hypokalaemia.
Topics: Adult; Aged; Amiloride; Blood Pressure; Body Weight; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Male; Middle Aged; Pyrazines; Sodium; Spironolactone; Time Factors; Urea | 1973 |
Antihypertensive actions of diuretics. Comparative study of an aldosterone antagonist and a thiazide, alone and together.
Topics: Angiotensin II; Antihypertensive Agents; Blood Pressure Determination; Blood Volume Determination; Clinical Trials as Topic; Humans; Hydrochlorothiazide; Hypertension; Norepinephrine; Placebos; Potassium; Spironolactone | 1968 |
Moderate sodium restriction and diuretics in the treatment of hypertension.
Topics: Adult; Body Weight; Clinical Trials as Topic; Diet, Sodium-Restricted; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Placebos; Potassium; Sodium; Spironolactone; Uric Acid | 1973 |
Treatment of low-renin essential hypertension. Comparison of spironolactone and a hydrochlorothiazide-triamterene combination.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Blood Urea Nitrogen; Clinical Trials as Topic; Creatinine; Drug Therapy, Combination; Extracellular Space; Female; Humans; Hydrochlorothiazide; Hypertension; Informed Consent; Male; Middle Aged; Placebos; Posture; Potassium; Renin; Sodium; Spironolactone; Triamterene | 1974 |
Low-renin hypertension. Restoration of normotension and renin responsiveness.
Topics: Administration, Oral; Clinical Trials as Topic; Diet; Drug Therapy, Combination; Furosemide; Humans; Hydrochlorothiazide; Hypertension; Methods; Placebos; Posture; Potassium; Renin; Sodium; Spironolactone; Time Factors | 1974 |
[Clinical amd metabolic results of a particular combination thiazide-antialdosterone in heart failure].
Topics: Clinical Trials as Topic; Diuretics; Drug Combinations; Drug Synergism; Ethacrynic Acid; Heart Failure; Humans; Hydrochlorothiazide; Potassium; Sodium; Sodium Chloride Symporter Inhibitors; Spironolactone | 1974 |
Comparative efficacy of spironolactone and hydrochlorothiazide (separately and in combination) in cirrhotic edema.
Topics: Ascites; Clinical Trials as Topic; Drug Synergism; Humans; Hydrochlorothiazide; Liver Cirrhosis; Spironolactone | 1967 |
High doses of spironolactone (Aldactone, SC-14266, Verospirone) alone and in combination with triamterene and-or diuretics in the treatment of refractory edema associated with secondary hyperaldosteronism.
Topics: Adult; Aged; Body Weight; Chlorides; Clinical Trials as Topic; Clopamide; Creatinine; Diet, Sodium-Restricted; Diuresis; Drug Synergism; Edema; Ethacrynic Acid; Female; Furosemide; Glomerular Filtration Rate; Heart Failure; Humans; Hydrochlorothiazide; Hyperaldosteronism; Liver Cirrhosis; Male; Middle Aged; Natriuresis; Nephrotic Syndrome; Potassium; Sodium; Spironolactone; Triamterene | 1970 |
[Treatment of the hypertensive patient. Value of Amiloride during saldiuretic treatment].
Topics: Adult; Amiloride; Diuretics; Female; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Kidney Function Tests; Male; Middle Aged; Natriuresis; Potassium; Pyrazines; Spironolactone; Water-Electrolyte Balance | 1972 |
Treatment of hypertension with spironolactone. Double-blind study.
Topics: Clinical Trials as Topic; Humans; Hydrochlorothiazide; Hypertension; Spironolactone | 1966 |
Therapy with combinations of diuretic agents: comparative studies.
Topics: Acetazolamide; Acid-Base Equilibrium; Aged; Clinical Trials as Topic; Drug Synergism; Furosemide; Humans; Hydrochlorothiazide; Liver Cirrhosis; Natriuresis; Spironolactone; Sulfonamides; Water-Electrolyte Balance | 1966 |
Amiloride (MK-870), a new antikaluretic diuretic. Comparison to other antikaluretic diuretics in patients with liver disease and ascites.
Topics: Acid-Base Equilibrium; Amidines; Ascites; Autopsy; Carcinoma; Diuretics; Ethacrynic Acid; Humans; Hydrochlorothiazide; Hydrogen-Ion Concentration; Hyperkalemia; Liver Cirrhosis; Liver Neoplasms; Pyrazines; Spironolactone; Triamterene; Water-Electrolyte Balance | 1970 |
Treatment of gastric ulcer with carbenoxolone: antagonistic effect of spironolactone.
Topics: Adult; Aged; Body Weight; Female; Glycyrrhiza; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Plants, Medicinal; Spironolactone; Stomach Ulcer; Terpenes; Wound Healing | 1968 |
Interaction of diuretics and non-steroidal anti-inflammatory drugs in man.
Topics: Adult; Aldosterone; Creatinine; Diuretics; Drug Interactions; Female; Furosemide; Humans; Hydrochlorothiazide; Indomethacin; Male; Potassium; Prostaglandins E; Prostaglandins F; Renin; Sodium; Spironolactone; Triamterene; Vasopressins | 1983 |
Comparison of six treatments of ascites in patients with liver cirrhosis. A clinical trial.
Topics: Amiloride; Ascites; Blood Chemical Analysis; Clinical Trials as Topic; Diet, Sodium-Restricted; Diuretics; Drainage; Drug Combinations; Furosemide; Humans; Hydrochlorothiazide; Liver Cirrhosis; Random Allocation; Spironolactone | 1983 |
Potassium-sparing diuretics: interaction with digoxin in elderly men.
Topics: Aged; Clinical Trials as Topic; Digoxin; Diuretics; Drug Interactions; Erythrocytes; Female; Furosemide; Humans; Hydrochlorothiazide; Male; Middle Aged; Potassium; Spironolactone; Triamterene | 1984 |
Serum cholesterol during treatment of hypertension with diuretic drugs.
Topics: Chlorthalidone; Cholesterol; Diuretics; Humans; Hydrochlorothiazide; Hypertension; Male; Random Allocation; Reserpine; Spironolactone; Triglycerides | 1984 |
Effect of moduretic and aldactone on electrolytes in skeletal muscle in patients on long-term diuretic therapy.
Topics: Cardiomyopathies; Humans; Hydrochlorothiazide; Hypertension; Magnesium; Muscles; Potassium; Spironolactone | 1982 |
The patient with mild to moderate essential hypertension: peripheral renin activity and a comparative drug study.
Topics: Adult; Age Factors; Blood Pressure; Chlorothiazide; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Female; Furosemide; Humans; Hydrochlorothiazide; Hypertension; Male; Propranolol; Renin; Sex Factors; Spironolactone | 1981 |
[Treatment of benign essential hypertension with an association of spironolactone and thiabutazide: an open multicenter study in general practice (author's transl)].
Topics: Antihypertensive Agents; Clinical Trials as Topic; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Spironolactone | 1981 |
A double-blind comparison of spironolactone and hydrochlorothiazide in hypertensive patients treated with metoprolol.
Topics: Adult; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Metoprolol; Middle Aged; Propanolamines; Spironolactone | 1982 |
The bioavailability of spironolactone hydrochlorothiazide combination preparation.
Topics: Adult; Antihypertensive Agents; Biological Availability; Drug Combinations; Electrolytes; Humans; Hydrochlorothiazide; Kidney; Male; Spironolactone | 1982 |
Interaction of conventional and antikaliuretic diuretics with the renal prostaglandin system.
Topics: Adult; Diuretics; Drug Interactions; Female; Furosemide; Humans; Hydrochlorothiazide; Indomethacin; Male; Potassium; Prostaglandins E; Prostaglandins F; Sodium; Spironolactone | 1980 |
A comparison of the potassium and magnesium-sparing properties of amiloride and spironolactone in diuretic-treated normal subjects.
Topics: Adult; Aldosterone; Amiloride; Double-Blind Method; Drug Interactions; Erythrocytes; Humans; Hydrochlorothiazide; Intracellular Fluid; Magnesium; Male; Potassium; Spironolactone | 1993 |
Spironolactone abolishes the relationship between aldosterone and plasminogen activator inhibitor-1 in humans.
Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Cross-Over Studies; Diuretics; Double-Blind Method; Fibrinolysis; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Plasminogen Activator Inhibitor 1; Sodium Chloride Symporter Inhibitors; Spironolactone | 2002 |
Effects of eplerenone, enalapril, and eplerenone/enalapril in patients with essential hypertension and left ventricular hypertrophy: the 4E-left ventricular hypertrophy study.
Topics: Adult; Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Enalapril; Eplerenone; Female; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Magnetic Resonance Imaging; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Myocardium; Potassium; Renin-Angiotensin System; Spironolactone; Treatment Outcome | 2003 |
Differing effects of mineralocorticoid receptor-dependent and -independent potassium-sparing diuretics on fibrinolytic balance.
Topics: Adult; Cross-Over Studies; Diuretics; Double-Blind Method; Electrolytes; Female; Fibrinolysis; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Plasminogen Activator Inhibitor 1; Potassium; Receptors, Mineralocorticoid; Renin-Angiotensin System; Sodium Chloride Symporter Inhibitors; Spironolactone; Triamterene | 2005 |
The effects of thiazide and thiazide-potassium sparing diuretics on fibrinolytic system parameters.
Topics: Amiloride; Antihypertensive Agents; Diuretics; Drug Therapy, Combination; Female; Fibrinolysis; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Plasminogen Activator Inhibitor 1; Spironolactone; Tissue Plasminogen Activator; Treatment Outcome | 2006 |
Effect of various diuretic treatments on rosiglitazone-induced fluid retention.
Topics: Adult; Aged; Aged, 80 and over; Diabetes Mellitus, Type 2; Diuretics; Drug Therapy, Combination; Edema; Extracellular Fluid; Female; Furosemide; Hematocrit; Humans; Hydrochlorothiazide; Hypoglycemic Agents; Male; Middle Aged; Plasma Volume; Rosiglitazone; Spironolactone; Sulfonylurea Compounds; Thiazolidinediones | 2006 |
Beneficial effects of eplerenone versus hydrochlorothiazide on coronary circulatory function in patients with diabetes mellitus.
Topics: Adult; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Blood Glucose; Blood Pressure; Brachial Artery; Coronary Circulation; Cross-Over Studies; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diuretics; Drug Therapy, Combination; Eplerenone; Female; Humans; Hydrochlorothiazide; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Pilot Projects; Potassium; Renal Circulation; Spironolactone | 2007 |
Triple pharmacological blockade of the renin-angiotensin-aldosterone system in nondiabetic CKD: an open-label crossover randomized controlled trial.
Topics: Acetylglucosaminidase; Adult; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Benzoates; Chronic Disease; Cilazapril; Collagen Type III; Cross-Over Studies; Disease Progression; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Kidney Diseases; Male; Mineralocorticoid Receptor Antagonists; Potassium; Proteinuria; Renin-Angiotensin System; Spironolactone; Telmisartan | 2008 |
Spironolactone attenuates oxidative stress in patients with chronic kidney disease.
Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antioxidants; Benzimidazoles; Benzoates; Chronic Disease; Cilazapril; Creatinine; Cross-Over Studies; Dinoprost; Diuretics; Female; Humans; Hydrochlorothiazide; Kidney Diseases; Male; Mineralocorticoid Receptor Antagonists; Oxidative Stress; Spironolactone; Telmisartan | 2008 |
[Impact of patient compliance on the outcomes in hypertensive patients receiving hydrochlorothiazide based combination therapy with spironolactone or captopril].
Topics: Aged; Antihypertensive Agents; Captopril; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Patient Compliance; Spironolactone; Treatment Outcome | 2008 |
Impact of aldosterone receptor blockade compared with thiazide therapy on sympathetic nervous system function in geriatric hypertension.
Topics: Aged; Aldosterone; Blood Pressure; Body Composition; Catecholamines; Diuretics; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Lipoproteins, HDL; Lipoproteins, LDL; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Norepinephrine; Patient Selection; Spironolactone; Sympathetic Nervous System | 2010 |
Spironolactone and hydrochlorothiazide decrease vascular stiffness and blood pressure in geriatric hypertension.
Topics: Age Factors; Aged; Antihypertensive Agents; Blood Flow Velocity; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Spironolactone; Treatment Outcome; Vasodilation | 2010 |
Evaluation of spironolactone plus hydrochlorothiazide in reducing proteinuria in type 2 diabetic nephropathy.
Topics: Adult; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Blood Glucose; Diabetes Mellitus, Type 2; Diuretics; Double-Blind Method; Drug Therapy, Combination; Female; Glycated Hemoglobin; Humans; Hydrochlorothiazide; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Potassium; Proteinuria; Spironolactone | 2015 |
Mineralocorticoid receptor blockade improves coronary microvascular function in individuals with type 2 diabetes.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Coronary Circulation; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diuretics; Double-Blind Method; Drug Therapy, Combination; Enalapril; Female; Humans; Hydrochlorothiazide; Male; Microcirculation; Middle Aged; Mineralocorticoid Receptor Antagonists; Spironolactone; Treatment Outcome | 2015 |
[The use of verospiron and the degree of platelet aggregation in arterial hypertension with abdominal obesity].
Topics: Comorbidity; Diuretics; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Obesity, Abdominal; Platelet Aggregation; Spironolactone; Treatment Outcome | 2014 |
Spironolactone is superior to hydrochlorothiazide for blood pressure control and arterial stiffness improvement: A prospective study.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Drug Monitoring; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Spironolactone; Treatment Outcome; Vascular Stiffness | 2018 |
Influence of Hypersensitive C-Reactive Protein on the Effect of Continuous Antihypertensive Pharmacological Therapy.
Topics: Antihypertensive Agents; Blood Pressure; C-Reactive Protein; Captopril; Humans; Hydrochlorothiazide; Hypertension; Nitrendipine; Spironolactone | 2022 |
188 other study(ies) available for spironolactone and hydrochlorothiazide
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Convenient QSAR model for predicting the complexation of structurally diverse compounds with beta-cyclodextrins.
Topics: beta-Cyclodextrins; Hydrophobic and Hydrophilic Interactions; Organic Chemicals; Quantitative Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Comparative effect of spironolactone and hydrochlorothiazide therapy in experimental renal hypertension of Rhesus monkeys.
Topics: Animals; Female; Haplorhini; Hydrochlorothiazide; Hypertension, Renal; Macaca mulatta; Male; Spironolactone | 1978 |
Reduced response of plasma aldosterone to acute ACTH stimulation during long-term treatment with spironolactone in essential hypertension.
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Blood Pressure; Humans; Hydrochlorothiazide; Hydrocortisone; Hypertension; Middle Aged; Potassium; Renin; Sodium; Spironolactone | 1979 |
Raised serum lipid concentrations during diuretic treatment of hypertension: a study of predictive indexes.
Topics: Adult; Cholesterol; Diuretics; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Myocardial Infarction; Risk; Spironolactone; Triglycerides | 1978 |
Idiopathic edema as a cause of nonarticular rheumatism.
Topics: Adult; Body Weight; Capillary Permeability; Chlorthalidone; Dextroamphetamine; Edema; Female; Humans; Hydrochlorothiazide; Middle Aged; Rheumatic Diseases; Sodium; Spironolactone; Water-Electrolyte Balance | 1979 |
Aldosterone antagonism studies in the rhesus monkey.
Topics: Administration, Oral; Aldosterone; Animals; Canrenone; Diuresis; Dose-Response Relationship, Drug; Female; Haplorhini; Hydrochlorothiazide; Injections, Intramuscular; Macaca mulatta; Mineralocorticoid Receptor Antagonists; Potassium; Sodium; Spironolactone | 1977 |
Hypokalemic periodic paralysis.
Topics: Adolescent; Humans; Hydrochlorothiazide; Hypokalemia; Male; Paralyses, Familial Periodic; Potassium Chloride; Spironolactone | 1979 |
[The combination of propranolol, hydrochlorothiazide and spironolactone in the treatment of essential arterial hypertension].
Topics: Adult; Aged; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Propranolol; Spironolactone | 1979 |
Treatment of hypertension in aviators: a clinical trial with Aldactazide.
Topics: Adult; Aerospace Medicine; Blood Volume; Drug Combinations; Electrolytes; Humans; Hydrochlorothiazide; Hypertension; Kidney; Liver; Liver Function Tests; Male; Spironolactone; Stress, Physiological | 1978 |
Comparison of the antihypertensive and hormonal effects of a cardioselective beta-blocker, acebutolol, and diuretics in essential hypertension.
Topics: Acebutolol; Adult; Aldosterone; Amiloride; Blood Pressure; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Renin; Spironolactone | 1978 |
Effects of Aldactazide and DOCA injections on saline preference in Gerbils (Meriones unguiculatus).
Topics: Animals; Choice Behavior; Desoxycorticosterone; Drinking; Drug Combinations; Gerbillinae; Hydrochlorothiazide; Male; Saline Solution, Hypertonic; Spironolactone | 1978 |
[Comparison of spironolactone and amiloride combined with hydrochlorothiazide in the treatment of slight or moderate hypertension].
Topics: Amiloride; Blood Glucose; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Pyrazines; Spironolactone; Uric Acid | 1978 |
A circulating renin activator in essential hypertension.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Contraceptives, Oral; Diuretics; Enzyme Activation; Functional Laterality; Haplorhini; Humans; Hydrochlorothiazide; Hypertension; In Vitro Techniques; Kinetics; Renal Artery Obstruction; Renin; Sodium; Spironolactone | 1975 |
Mexrenoate potassium: a steroidal aldosterone antagonist and antihypertensive.
Topics: Androstenols; Animals; Antihypertensive Agents; Blood Pressure; Diuresis; Dogs; Female; Heart Rate; Hydrochlorothiazide; Mineralocorticoid Receptor Antagonists; Placebos; Spironolactone | 1977 |
[Change in rheographic properties of blood in congestive circulatory insufficiency treated with diuretics].
Topics: Adult; Aged; Blood Circulation; Blood Viscosity; Diuretics; Erythrocyte Aggregation; Ethacrynic Acid; Female; Heart Failure; Hematocrit; Humans; Hydrochlorothiazide; Male; Middle Aged; Platelet Aggregation; Plethysmography, Impedance; Spironolactone | 1977 |
Diuretic therapy and response of essential hypertension to saralasin.
Topics: Adult; Aged; Angiotensin II; Blood Pressure; Diuretics; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Renin; Saralasin; Spironolactone; Stimulation, Chemical | 1977 |
Identification of selected antihypertensive drugs by thin-layer chromatography.
Topics: Antihypertensive Agents; Chromatography, Thin Layer; Diuretics; Humans; Hydrochlorothiazide; Methyldopa; Reserpine; Sodium Chloride Symporter Inhibitors; Spironolactone; Triamterene | 1977 |
Office management of hypertension.
Topics: Antihypertensive Agents; Diuretics; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Physical Examination; Physicians, Family; Potassium; Propranolol; Spironolactone; Triamterene | 1976 |
[Effect of certain diuretics on thyroid function in rats].
Topics: Acetazolamide; Animals; Diuretics; Ethacrynic Acid; Furosemide; Hydrochlorothiazide; Iodine Radioisotopes; Male; Mersalyl; Organ Size; Rats; Spironolactone; Thyroid Gland | 1976 |
In vitro and in vivo availability of spironolactone from oral dosage forms.
Topics: Animals; Biological Availability; Canrenone; Dogs; Drug Combinations; Drug Compounding; Drug Interactions; Excipients; Female; Half-Life; Hardness Tests; Hydrochlorothiazide; Kinetics; Solubility; Solutions; Spironolactone; Tablets | 1976 |
[Use of aldactone-saltucine in patients with heart failure].
Topics: Adult; Aged; Aldosterone; Body Weight; Butanes; Chlorides; Diuretics; Drug Combinations; Drug Evaluation; Heart Failure; Humans; Hydrochlorothiazide; Middle Aged; Natriuresis; Potassium; Sodium; Spironolactone | 1975 |
[Use of aldactone-saltucine for patients with chronic circulatory insufficiency].
Topics: Adult; Aged; Butanes; Creatinine; Diuresis; Diuretics; Drug Combinations; Drug Evaluation; Female; Furosemide; Glomerular Filtration Rate; Heart Failure; Humans; Hydrochlorothiazide; Kidney Tubules; Male; Middle Aged; Natriuresis; Potassium; Spironolactone; Time Factors | 1975 |
[Spironolactone and thiabutazide in the treatment of essential hypertension (author's transl)].
Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Body Weight; Butanes; Female; Furosemide; Humans; Hydrochlorothiazide; Hypertension; Natriuresis; Placebos; Potassium; Pregnancy; Renin; Sodium; Spironolactone; Time Factors | 1975 |
Azolimine: a nonsteroidal antagonist of the effects of mineralocorticoids on renal electrolyte excretion.
Topics: Adrenal Glands; Adrenalectomy; Amiloride; Animals; Desoxycorticosterone; Dogs; Hydrochlorothiazide; Imidazoles; Imines; Kidney; Male; Mineralocorticoids; Potassium; Rats; Sodium; Spironolactone; Sulfonamides | 1975 |
Spironolactone, a reassessment.
Topics: Diuresis; Drug Combinations; Humans; Hydrochlorothiazide; Hyperaldosteronism; Hypertension; Hypokalemia; Spironolactone | 1975 |
Aldactazide-induced consummatory and operant responding to sodium by rats.
Topics: Animals; Conditioning, Operant; Drinking; Drug Combinations; Female; Hydrochlorothiazide; Male; Rats; Saline Solution, Hypertonic; Sodium; Spironolactone; Water; Water Deprivation | 1975 |
Low renin essential hypertension in a child.
Topics: Aldosterone; Child; Circadian Rhythm; Dexamethasone; Humans; Hydrochlorothiazide; Hydrocortisone; Hypertension; Male; Renin; Spironolactone | 1976 |
HPLC-photolysis-electrochemical detection in pharmaceutical analysis: application to the determination of spironolactone and hydrochlorothiazide in tablets.
Topics: Chromatography, High Pressure Liquid; Electrochemistry; Hydrochlorothiazide; Hydrogen-Ion Concentration; Methanol; Phosphates; Photolysis; Spironolactone; Tablets | 1990 |
European experience with spironolactone and thiazide diuretic as antihypertensive therapy.
Topics: Diuretics; Drug Combinations; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Sodium Chloride Symporter Inhibitors; Spironolactone | 1990 |
[Effect of captopril therapy on sodium and water excretion in patients with liver cirrhosis and ascites].
Topics: Adult; Aged; Ascites; Blood Pressure; Captopril; Diuresis; Diuretics; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Furosemide; Glomerular Filtration Rate; Humans; Hydrochlorothiazide; Liver Cirrhosis; Male; Middle Aged; Renin-Angiotensin System; Sodium Chloride Symporter Inhibitors; Spironolactone; Water-Electrolyte Balance | 1989 |
Regulation of renal peripheral benzodiazepine receptors by anion transport inhibitors.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Acetazolamide; Amiloride; Animals; Anions; Anthracenes; Biological Transport; Bumetanide; Furosemide; Hydrochlorothiazide; Kidney; Kinetics; Male; Myocardium; Ouabain; Rats; Rats, Inbred Strains; Receptors, GABA-A; Spironolactone | 1988 |
[Respiratory insufficiency in mucoviscidosis. Pathophysiologic aspects of conservative drug therapy].
Topics: Acid-Base Equilibrium; Child; Combined Modality Therapy; Cystic Fibrosis; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Potassium; Respiratory Insufficiency; Sodium Chloride; Spironolactone; Theophylline | 1989 |
Long-term metabolic effects of spironolactone and thiazides combined with potassium-sparing agents for treatment of essential hypertension.
Topics: Amiloride; Benzothiadiazines; Blood Glucose; Diuretics; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Lipids; Male; Middle Aged; Potassium; Sodium Chloride Symporter Inhibitors; Spironolactone; Time Factors; Triamterene | 1988 |
Mineral excretion in premature infants receiving various diuretic therapies.
Topics: Birth Weight; Bone Diseases, Metabolic; Diuretics; Drug Therapy, Combination; Female; Furosemide; Humans; Hydrochlorothiazide; Infant, Newborn; Infant, Premature, Diseases; Male; Minerals; Nephrocalcinosis; Spironolactone | 1988 |
Efficacy of verapamil--hydrochlorothiazide-spironolactone therapy in hypertensive black patients.
Topics: Adult; Aged; Black People; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Posture; Spironolactone; Verapamil | 1987 |
What's new in diuretic therapy.
Topics: Acetazolamide; Acid-Base Imbalance; Biological Transport; Diuretics; Drug Resistance; Ethacrynic Acid; Furosemide; Humans; Hydrochlorothiazide; Hyperkalemia; Hypernatremia; Hypokalemia; Hyponatremia; Indapamide; Kidney Tubules, Distal; Kidney Tubules, Proximal; Loop of Henle; Metolazone; Osmolar Concentration; Spironolactone; Triamterene; Vasopressins | 1986 |
[Therapy of primary aldosteronism].
Topics: Adenoma; Adrenal Cortex Diseases; Adrenal Cortex Neoplasms; Adrenalectomy; Carcinoma; Diagnosis, Differential; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hyperaldosteronism; Hyperplasia; Mineralocorticoid Receptor Antagonists; Spironolactone | 1986 |
Essential hypertension: a metabolic cause? A hypothesis.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Calcium; Captopril; Female; Humans; Hydrochlorothiazide; Hypertension; Lactates; Lactic Acid; Male; Middle Aged; Potassium; Potassium Chloride; Propranolol; Renin; Spironolactone | 1985 |
Colorimetric analysis of some diuretic drugs: hydrochlorothiazide and spironolactone.
Topics: Chemical Phenomena; Chemistry; Cobalt; Colorimetry; Hydrochlorothiazide; Hydrogen-Ion Concentration; Spironolactone; Tablets; Time Factors | 1985 |
Nephrotic syndrome associated with bacteraemia after shunt operations for hydrocephalus.
Topics: Edema; Escherichia coli; Female; Fluorescent Antibody Technique; Glomerulonephritis; Humans; Hydrocephalus; Hydrochlorothiazide; Nephrotic Syndrome; Postoperative Complications; Sepsis; Spironolactone; Staphylococcal Infections | 1965 |
Sodium retention after adrenal enucleation: drug and salt appetite studies.
Topics: Adrenal Glands; Adrenal Medulla; Adrenalectomy; Aminoglutethimide; Animals; Appetite; Body Weight; Depression, Chemical; Diuretics; Drinking; Heparinoids; Hydrochlorothiazide; Male; Methandrostenolone; Metyrapone; Mineralocorticoid Receptor Antagonists; Natriuresis; Potassium; Rats; Regeneration; Sodium; Sodium Chloride; Spironolactone; Water-Electrolyte Balance | 1968 |
[The effect of hydrochlorthiazide on the blood sugar-increasing action of diazoxide].
Topics: Animals; Antihypertensive Agents; Carbohydrate Metabolism; Diazoxide; Hydrochlorothiazide; Hyperglycemia; Potassium Deficiency; Rats; Spironolactone | 1966 |
Inhibition of aldosterone production in diuretic-induced hyperaldosteronism by aldosterone antagonist canrenone in man.
Topics: Aldosterone; Butanes; Depression, Chemical; Diuresis; Hematocrit; Humans; Hydrochlorothiazide; Hyperaldosteronism; Ketosteroids; Lactones; Male; Mineralocorticoid Receptor Antagonists; Natriuresis; Potassium; Pregnadienes; Sodium; Spironolactone; Time Factors | 1974 |
The effect of saluretics and spironolactone on aldosterone production and electrolyte excretion in man.
Topics: Adult; Aldosterone; Butanes; Diuresis; Female; Furosemide; Humans; Hydrochlorothiazide; Hyperaldosteronism; Male; Natriuresis; Potassium; Sodium; Spironolactone | 1974 |
[Angiotensin and saluretics in nephrogenic diabetes insipidus of early infancy].
Topics: Angiotensin II; Body Temperature; Chlorthalidone; Diabetes Insipidus; Electrolytes; Female; Furosemide; Humans; Hydrochlorothiazide; Hypernatremia; Infant, Newborn; Kidney; Kidney Tubules; Sodium; Spironolactone; Sweat | 1967 |
Low renin hypertension and the adrenal cortex.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Blood Pressure; Corticosterone; Desoxycorticosterone; Diuresis; Humans; Hydrochlorothiazide; Hyperaldosteronism; Hypertension; Hypokalemia; Indoles; Male; Pyridines; Renin; Secretory Rate; Spironolactone; Sulfonic Acids | 1972 |
[Plasma aldosterone levels in primary aldosteronism. 1. Renin-angiotensin system and aldosterone].
Topics: Aldosterone; Angiotensin II; Enzyme Activation; Furosemide; Humans; Hydrochlorothiazide; Hyperaldosteronism; Posture; Renin; Spironolactone | 1973 |
Adaptation to the natriuretic actions of hydrochlorothiazide, frusemide and amiloride, by rats.
Topics: Adaptation, Physiological; Adrenal Glands; Adrenalectomy; Aldosterone; Amiloride; Animals; Corticosterone; Diuresis; Diuretics; Female; Furosemide; Hydrochlorothiazide; Juxtaglomerular Apparatus; Natriuresis; Potassium; Pyrazines; Rats; Renin; Sodium; Sodium Chloride; Spironolactone; Time Factors | 1972 |
Red blood cell potassium as a measure of body potassium in thiazide-treated patients with essential hypertension.
Topics: Depression, Chemical; Drug Therapy, Combination; Erythrocytes; Female; Hematocrit; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Potassium Chloride; Sex Factors; Spironolactone; Stimulation, Chemical | 1974 |
Idiopathic edema.
Topics: Adult; Age Factors; Aldosterone; Edema; Female; Heart Failure; Humans; Hydrochlorothiazide; Hydrostatic Pressure; Hyperaldosteronism; Liver Cirrhosis; Male; Nephrosis; Osmotic Pressure; Posture; Renin; Sex Factors; Sodium; Spironolactone; Water-Electrolyte Balance | 1974 |
Plasma aldosterone in essential hypertension with low renin activity.
Topics: Aldosterone; Body Weight; Corticosterone; Cushing Syndrome; Furosemide; Humans; Hydrochlorothiazide; Hypertension; Hypertension, Renal; Kidney Failure, Chronic; Metabolism, Inborn Errors; Mixed Function Oxygenases; Posture; Potassium; Radioimmunoassay; Renin; Spironolactone | 1974 |
[Effects of spironolactone and hydrochlorothiazide on blood pressure levels and blood potassium. Controlled studies on hypertensive patients].
Topics: Adult; Blood Pressure; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Spironolactone | 1974 |
Antikaluretic action of amiloride.
Topics: Amiloride; Animals; Calcium; Diuretics; Furosemide; Hydrochlorothiazide; Kidney; Potassium; Pyrazines; Rats; Spironolactone | 1973 |
[Is essential hypertension still a disease entity? Definition of hyporeninemic hypertension].
Topics: Aldosterone; Amiloride; Chlorthalidone; Diagnosis, Differential; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Mineralocorticoids; Prognosis; Renin; Sodium Chloride; Spironolactone; Sympathetic Nervous System | 1974 |
Similar effects of hydrochlorothiazide and spironolactone on plasma renin activity in essential hypertension.
Topics: Adult; Blood Pressure; Blood Volume; Evaluation Studies as Topic; Humans; Hydrochlorothiazide; Hypertension; Middle Aged; Plasma; Potassium; Renin; Sodium; Spironolactone | 1972 |
[Hyperuricemia due to diuretics].
Topics: Acetazolamide; Aged; Chlorothiazide; Chlorthalidone; Diuretics; Ethacrynic Acid; Furosemide; Gout; Humans; Hydrochlorothiazide; Middle Aged; Spironolactone; Sulfonamides; Triamterene; Uric Acid | 1973 |
Problems in therapy for the hypertensive patient.
Topics: Antihypertensive Agents; Blood Pressure; Carotid Sinus; Diuretics; Electric Stimulation; Ethacrynic Acid; Female; Furosemide; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Hypertension, Malignant; Hypertension, Renal; Hypotension, Orthostatic; Male; Methyldopa; Nephrectomy; Phytotherapy; Plants, Medicinal; Posture; Rauwolfia; Spironolactone; Uremia | 1973 |
How to treat arterial hypertension.
Topics: Antihypertensive Agents; Chlorothiazide; Chlorthalidone; Cooperative Behavior; Diazoxide; Diuretics; Ethacrynic Acid; Furosemide; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Kidney; Methyldopa; Physician-Patient Relations; Reserpine; Spironolactone; Sulfonamides; Triamterene | 1973 |
Volume-dependent essential and steroid hypertension.
Topics: Adult; Aged; Aldosterone; Diet, Sodium-Restricted; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hyperaldosteronism; Hypertension; Male; Middle Aged; Natriuresis; Plasma Volume; Renin; Sodium; Spironolactone; Water-Electrolyte Balance | 1973 |
Aldactazide-induced sodium appetite in rats.
Topics: Animals; Appetite; Drinking; Drug Combinations; Hydrochlorothiazide; Hypertonic Solutions; Isotonic Solutions; Male; Rats; Sodium; Sodium Chloride; Spironolactone; Water | 1973 |
Spironolactone as a nonspecific treatment for primary aldosteronism.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Blood Urea Nitrogen; Body Weight; Carbon Dioxide; Creatinine; Diet, Sodium-Restricted; Female; Furosemide; Humans; Hydrochlorothiazide; Hyperaldosteronism; Male; Middle Aged; Plasma Volume; Potassium; Renin; Sodium; Spironolactone | 1973 |
Fluorescein circulation time and the treatment of hypertension in the aged.
Topics: Adult; Age Factors; Aged; Blood Circulation Time; Blood Pressure; Carbamates; Ethacrynic Acid; Female; Fluoresceins; Furosemide; Glomerular Filtration Rate; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Kidney Failure, Chronic; Male; Methyldopa; Middle Aged; Potassium; Reserpine; Spironolactone | 1973 |
Value and toxicity of therapy for idiopathic nephrotic syndrome in the child.
Topics: Anti-Bacterial Agents; Blood Protein Disorders; Child; Chlorothiazide; Cyclophosphamide; Diet, Sodium-Restricted; Dietary Proteins; Ethacrynic Acid; Furosemide; Glucocorticoids; Humans; Hydrochlorothiazide; Hypertension, Renal; Methyldopa; Nephrotic Syndrome; Plasma Substitutes; Rest; Serum Albumin; Spironolactone | 1973 |
[Pharmacological studies on diuretics. 6. Actions of various diuretics on experimental nephrotic rats].
Topics: Acetazolamide; Aminophylline; Animals; Diuresis; Diuretics; Ethacrynic Acid; Furosemide; Glycosides; Hydrochlorothiazide; Hypertension; Male; Nephritis; Organomercury Compounds; Potassium; Pyrans; Rats; Sodium; Sodium Chloride Symporter Inhibitors; Spironolactone; Sulfonamides; Triamterene | 1973 |
Syndrome of hypernatremia, hypodipsia and partial diabetes insipidus: a new interpretation.
Topics: Adolescent; Chlorpropamide; Diabetes Insipidus; Drinking; Female; Humans; Hydrochlorothiazide; Hypernatremia; Nicotine; Potassium; Sodium; Sodium Chloride; Spironolactone; Syndrome; Thirst; Urination; Vasopressins; Water Deprivation | 1974 |
Sodium intake induced by aldactazide and formalin injections.
Topics: Animals; Appetite; Behavior, Animal; Drinking; Formaldehyde; Hydrochlorothiazide; Male; Milk; Rats; Sodium; Sodium Chloride; Spironolactone; Water | 1974 |
[Exchangeable sodium, total-body potassium, plasma volume, and hypotensive effect of various diuretics in patients with essential hypertension and low plasma renin level (author's transl)].
Topics: Adolescent; Adult; Amiloride; Blood Pressure; Blood Volume; Body Surface Area; Diuretics; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Posture; Potassium; Renin; Sodium; Spironolactone | 1974 |
[Respective roles of hemodynamic or humoral factors and of hypotensive or salidiuretic drugs in the development of essential hypertension].
Topics: Adult; Chlorthalidone; Diet, Sodium-Restricted; Electrocardiography; Guanethidine; Humans; Hydrochlorothiazide; Hypertension; Hypertension, Malignant; Male; Methyldopa; Middle Aged; Prognosis; Reserpine; Sodium; Spironolactone; Sympathectomy | 1965 |
Reversible bullous retinal detachment in chronic renal disease.
Topics: Adult; Angiography; Diet; Female; Fluorescence; Humans; Hydrochlorothiazide; Hypertension, Renal; Hyponatremia; Kidney Failure, Chronic; Kidney Transplantation; Male; Methyldopa; Papilledema; Peritoneal Dialysis; Retinal Detachment; Sodium; Spironolactone; Transplantation, Homologous | 1969 |
Interactions of spironolactone and hydrochlorothiazide with aspirin in the rat and dog.
Topics: Aldosterone; Animals; Aspirin; Corticosterone; Diuresis; Diuretics; Dogs; Drug Interactions; Female; Hydrochlorothiazide; Kidney; Male; Mineralocorticoids; Natriuresis; Potassium; Rats; Rats, Inbred Strains; Spironolactone | 1972 |
Dependence of arterial pressure on intravascular volume in treated hypertensive patients.
Topics: Adult; Aged; Arteries; Blood Pressure; Female; Furosemide; Guanethidine; Humans; Hydrazines; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Plasma Volume; Propranolol; Spironolactone; Triamterene | 1972 |
[Diuretics. 5. Effects of single or combined administration of diuretics in normal or spontaneously hypertensive rats].
Topics: Acetazolamide; Aminophylline; Animals; Chlorides; Diuretics; Drug Synergism; Hydrochlorothiazide; Hydroflumethiazide; Hypertension; Male; Methyclothiazide; Natriuresis; Organomercury Compounds; Potassium; Rats; Spironolactone; Sulfonamides; Triamterene | 1972 |
Spironolactone and hydrochlorothiazide in essential hypertension. Blood pressure response and plasma renin activity.
Topics: Adult; Blood Pressure; Body Weight; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Renin; Spironolactone | 1972 |
Treatment of hypertension with hydrochlorothiazide and spironolactone.
Topics: Blood Pressure; Blood Urea Nitrogen; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Potassium; Sodium; Spironolactone | 1969 |
Suppressed plasma renin activity in in hypertensive patients--its evaluation for the diagnosis of primary aldosteronism.
Topics: Aldosterone; Cushing Syndrome; Diet, Sodium-Restricted; Glomerulonephritis; Humans; Hydrochlorothiazide; Hyperaldosteronism; Hypertension; Hypertension, Renal; Kidney Neoplasms; Metabolic Diseases; Mixed Function Oxygenases; Pyelonephritis; Renin; Spironolactone; Stimulation, Chemical; Time Factors | 1969 |
Effects of hydrochlorothiazide, spironolactone and metyrapone on electrolyte excretion and zona glomerulosa width in the sodium depleted rat.
Topics: Adrenal Gland Diseases; Adrenal Glands; Adrenal Medulla; Animals; Diet, Sodium-Restricted; Hydrochlorothiazide; Hypertrophy; Male; Metyrapone; Natriuresis; Potassium; Rats; Spironolactone | 1970 |
A chick bioassay for oral diuretics.
Topics: Administration, Oral; Ammonium Chloride; Animal Feed; Animals; Biological Assay; Chickens; Chlorothiazide; Dioxins; Diuretics; Ethacrynic Acid; Hydrochlorothiazide; Lipids; Male; Methods; Pericardial Effusion; Spironolactone; Urea | 1971 |
[Prevention of potassium metabolism disorders arising during the treatment of cardiac insufficiency with diuretics].
Topics: Adult; Digitalis Glycosides; Diuretics; Drug Synergism; Female; Furosemide; Heart Failure; Humans; Hydrochlorothiazide; Male; Middle Aged; Potassium; Potassium Deficiency; Pteridines; Sodium; Spironolactone; Water-Electrolyte Balance | 1967 |
Small intestinal edema in cirrhosis: its disappearance with diuresis.
Topics: Edema; Humans; Hydrochlorothiazide; Hypoproteinemia; Intestinal Diseases; Liver Cirrhosis; Male; Middle Aged; Radiography; Serum Albumin; Spironolactone | 1968 |
The role of catecholamines in circulatory regulation on the chronic congestive heart failure. Clinical study of the urinary catecholamine excretion in the patients with chronic congestive heart failure.
Topics: Adolescent; Adult; Aged; Blood Pressure; Cardiomyopathies; Catecholamines; Coronary Disease; Digitalis Glycosides; Diuretics; Epinephrine; Female; Glomerular Filtration Rate; Guanethidine; Heart Defects, Congenital; Heart Failure; Heart Valve Diseases; Humans; Hydrochlorothiazide; Hypertension; Lanatosides; Male; Middle Aged; Norepinephrine; Potassium; Regional Blood Flow; Sodium; Spironolactone; Trichlormethiazide | 1968 |
[Clinical and biochemical study of the therapeutic effect of the diuretic triamterene in ascitogenic cirrhosis].
Topics: Adrenal Cortex Hormones; Ascites; Diuresis; Electrolytes; Humans; Hydrochlorothiazide; Liver Cirrhosis; Organomercury Compounds; Polythiazide; Spironolactone; Triamterene | 1968 |
[Influence of diuretics on the survival of 180 patients with cirrhosis of the liver and ascites].
Topics: Adult; Aged; Alcoholism; Ascites; Chlorothiazide; Chlorthalidone; Diuretics; Ethacrynic Acid; Humans; Hydrochlorothiazide; Liver Cirrhosis; Middle Aged; Spironolactone; Triamterene | 1969 |
The nephrotic syndrome in an elderly woman. An unusual association with an unusual response to therapy.
Topics: Aged; Biopsy; Body Weight; Chronic Disease; Diagnosis, Differential; Edema; Female; Humans; Hydrochlorothiazide; Kidney; Lymphocytes; Nephrotic Syndrome; Proteinuria; Pyelonephritis; Spironolactone | 1969 |
Hypotensive drug therapy in the management of hypertension.
Topics: Antihypertensive Agents; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Methyldopa; Pargyline; Reserpine; Spironolactone | 1969 |
Aldactoneà and aldactazideà.
Topics: Humans; Hydrochlorothiazide; Spironolactone | 1965 |
[Diuretic effect of triamterene in the experimental animal].
Topics: Adrenalectomy; Animals; Bicarbonates; Chlorides; Diuresis; Hydrochlorothiazide; Natriuresis; Potassium; Rats; Spironolactone; Triamterene | 1963 |
[Effects of triamterene in combination with other diuretics in liver cirrhosis].
Topics: Ascites; Bendroflumethiazide; Chlorothiazide; Humans; Hydrochlorothiazide; Liver Cirrhosis; Spironolactone; Triamterene | 1963 |
Renal failure with cirrhosis. Observations on the role of diuretics.
Topics: Acute Kidney Injury; Aminohippuric Acids; Ascites; Blood; Blood Volume; Creatine; Diuretics; Ethacrynic Acid; Furosemide; Humans; Hydrochlorothiazide; In Vitro Techniques; Kidney Function Tests; Liver Cirrhosis; Spironolactone; Urine | 1966 |
Medical management of ascites in hepatic cirrhosis.
Topics: Adolescent; Adult; Aminophylline; Anabolic Agents; Ascites; China; Diet, Sodium-Restricted; Female; Humans; Hydrochlorothiazide; Liver Cirrhosis; Liver Diseases, Parasitic; Liver Function Tests; Male; Middle Aged; Natriuresis; Schistosomiasis; Spironolactone | 1966 |
N-Amidino-3,5-diamino-6-chloropyrazine-carboxamide: an active diuretic in the carboxamide series.
Topics: Adrenalectomy; Aldosterone; Amides; Amidines; Animals; Desoxycorticosterone; Diuretics; Hydrochlorothiazide; Hydrocortisone; Male; Potassium; Pyrazines; Rats; Sodium; Spironolactone; Sulfhydryl Compounds | 1966 |
[Effects of the prolonged administration of thiazides and spirolactones on the response to water overloading in the normal subject].
Topics: Diuresis; Humans; Hydrochlorothiazide; Kidney Function Tests; Spironolactone; Water; Water-Electrolyte Balance | 1966 |
An azido pyrimidine diuretic (SC-16102): reversal of the Na retention induced by aldosterone.
Topics: Adrenalectomy; Aldosterone; Animals; Desoxycorticosterone; Diuretics; Hydrochlorothiazide; Male; Natriuresis; Potassium; Pyrimidines; Rats; Spironolactone | 1967 |
[Exchangeable potassium in normal persons and patients with arterial hypertension. With reference to the importance of diuretic therapy].
Topics: Adult; Aged; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Spironolactone; Triamterene | 1967 |
Acute diuretic induced hyperglycaemia in rats.
Topics: Acetazolamide; Adrenalectomy; Animals; Bendroflumethiazide; Chlorthalidone; Ergotamine; Ethacrynic Acid; Furosemide; Hydrochlorothiazide; Hyperglycemia; Male; Organomercury Compounds; Rats; Reserpine; Spironolactone | 1967 |
Comparison of oral isosorbide and intravenous mannitol as adjuncts to the diuresis of patients with cirrhosis of the liver.
Topics: Adult; Ascites; Humans; Hydrochlorothiazide; Injections, Intravenous; Isosorbide Dinitrate; Liver Cirrhosis; Mannitol; Middle Aged; Nitrites; Potassium; Sodium; Spironolactone | 1967 |
Azido pyrimidine diuretics (SC-16102, SC-16100): ADH antagonism assay in the rat.
Topics: Animals; Diuretics; Electrolytes; Furosemide; Hydrochlorothiazide; Male; Prednisone; Pyrimidines; Rats; Spironolactone; Triamterene; Vasopressins | 1967 |
Differential response to thiazides and spironolactone in primary aldosteronism.
Topics: Adult; Alkalosis; Blood Pressure; Diagnosis, Differential; Humans; Hydrochlorothiazide; Hyperaldosteronism; Hypertension; Hypokalemia; Male; Spironolactone | 1967 |
[The behavior of uricemia during treatment with spironolactone and with other diuretics].
Topics: Acetazolamide; Adolescent; Adult; Aged; Chlorthalidone; Clopamide; Diuretics; Ethacrynic Acid; Female; Furosemide; Gout; Heart Diseases; Humans; Hydrochlorothiazide; Hypertension; Kidney Diseases; Liver Cirrhosis; Male; Middle Aged; Organomercury Compounds; Spironolactone; Sulfonamides; Triamterene; Uric Acid | 1967 |
[Multi-centric study for the evaluation of the antihypertensive efficacy of hydrochlorothiazide and spironolactone association: comparison between 2 dosages schemes].
Topics: Adolescent; Adult; Aged; Child; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Spironolactone | 1983 |
[Electrolyte excretion following administration of various diuretics in healthy females].
Topics: Bendroflumethiazide; Circadian Rhythm; Diuretics; Drug Therapy, Combination; Electrolytes; Female; Furosemide; Humans; Hydrochlorothiazide; Spironolactone; Water-Electrolyte Balance | 1984 |
Plasma active and inactive renin and urinary kallikrein in normal subjects in response to hydrochlorothiazide, spironolactone or aldosterone administration.
Topics: Adult; Aldosterone; Blood Pressure; Enzyme Precursors; Female; Heart Rate; Humans; Hydrochlorothiazide; Kallikreins; Kinetics; Male; Renin; Sodium; Spironolactone | 1982 |
Clinical pharmacology of diuretics.
Topics: Canrenoic Acid; Canrenone; Diuretics; Ethacrynic Acid; Humans; Hydrochlorothiazide; Intestinal Absorption; Kinetics; Protein Binding; Sodium Chloride Symporter Inhibitors; Spironolactone | 1983 |
Symptomatic unruptured giant aneurysms: medical treatment.
Topics: Aged; Antihypertensive Agents; Female; Humans; Hydrochlorothiazide; Intracranial Aneurysm; Middle Aged; Phenytoin; Radiography; Spironolactone | 1982 |
Case study: drug-induced electrolyte changes.
Topics: Antihypertensive Agents; Drug Combinations; Female; Humans; Hydrochlorothiazide; Methyldopa; Middle Aged; Spironolactone; Water-Electrolyte Imbalance | 1982 |
Hypovolemia and permeability pulmonary edema associated with anaphylaxis.
Topics: Adult; Anaphylaxis; Capillary Permeability; Drug Combinations; Female; Humans; Hydrochlorothiazide; Lung; Pulmonary Edema; Respiration, Artificial; Shock; Spironolactone | 1981 |
[Analysis of active principles in pharmaceutical dosage forms by high pressure liquid chromatography - spironolactone and hydrochlorothiazide].
Topics: Chromatography, High Pressure Liquid; Drug Combinations; Hydrochlorothiazide; Spironolactone; Statistics as Topic | 1980 |
Drug therapy of ascites.
Topics: Ascites; Diuretics; Ethacrynic Acid; Furosemide; Humans; Hydrochlorothiazide; Sodium Chloride Symporter Inhibitors; Spironolactone; Triamterene | 1981 |
[Effect of verospiron and hypothiazide on the indices of electrolyte metabolism in neuroendocrinological obesity].
Topics: Adolescent; Adult; Diuretics; Female; Humans; Hydrochlorothiazide; Middle Aged; Mineralocorticoid Receptor Antagonists; Obesity; Sodium Chloride Symporter Inhibitors; Spironolactone; Water-Electrolyte Balance | 1980 |
Stability of labetalol hydrochloride, metoprolol tartrate, verapamil hydrochloride, and spironolactone with hydrochlorothiazide in extemporaneously compounded oral liquids.
Topics: Antihypertensive Agents; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Diuretics; Dosage Forms; Drug Compounding; Drug Stability; Humans; Hydrochlorothiazide; Labetalol; Metoprolol; Sodium Chloride Symporter Inhibitors; Spironolactone; Suspensions; Verapamil | 1996 |
Hyperkalaemia and diarrhoea in a patient with surreptitious ingestion of potassium sparing diuretics.
Topics: Chronic Disease; Diarrhea; Diuretics; Female; Humans; Hydrochlorothiazide; Hyperaldosteronism; Hyperkalemia; Middle Aged; Spironolactone; Triamterene | 1997 |
Use of peripheral temperature and core-peripheral temperature difference to predict cardiac output in dehydrated calves housed in a thermoneutral environment.
Topics: Animals; Animals, Newborn; Blood Pressure; Body Temperature; Cardiac Output; Cattle; Cattle Diseases; Dehydration; Diarrhea; Diuretics; Electrolytes; Furosemide; Heart Rate; Hemodynamics; Housing, Animal; Hydrochlorothiazide; Male; Spironolactone; Temperature | 1998 |
A reliable, practical, and economical protocol for inducing diarrhea and severe dehydration in the neonatal calf.
Topics: Animals; Animals, Newborn; Blood Glucose; Blood Proteins; Body Temperature; Body Weight; Cattle; Colostrum; Dehydration; Diarrhea; Electrolytes; Feces; Furosemide; Hemodynamics; Hydrochlorothiazide; Male; Spironolactone; Sucrose | 1998 |
Combined spironolactone-hydrochlorothiazide (Aldactazide) treatment in refractory congestive failure.
Topics: Chlorothiazide; Drug Combinations; Heart Failure; Hydrochlorothiazide; Lactones; Spironolactone | 1961 |
Use of spironolactone and hydrochlorothiazide in treatment of oedema.
Topics: Aldosterone; Chlorothiazide; Diuretics; Edema; Hydrochlorothiazide; Mineralocorticoid Receptor Antagonists; Spironolactone | 1960 |
[Effect of SC 9420, mercurial diuretic and hydrochlorothiazide on electrolyte excretion in liver cirrhosis].
Topics: Aldosterone; Chlorothiazide; Diuretics; Electrolytes; Humans; Hydrochlorothiazide; Liver Cirrhosis; Mineralocorticoid Receptor Antagonists; Organomercury Compounds; Spironolactone | 1959 |
[Respective indications of corticoids, hydrochlorothiazide and spirolactones in cirrhotic edema].
Topics: Adrenal Cortex Hormones; Chlorothiazide; Edema; Hydrochlorothiazide; Lactones; Liver Cirrhosis; Organic Chemicals; Spironolactone | 1960 |
Significance of aldosterone antagonism in the treatment of edema and ascites.
Topics: Aldosterone; Antihypertensive Agents; Ascites; Chlorothiazide; Diuretics; Edema; Humans; Hydrochlorothiazide; Lactones; Mineralocorticoid Receptor Antagonists; Spiro Compounds; Spironolactone | 1962 |
Metabolic studies on patients with resistant heart failure treated by spironolactone.
Topics: Diuresis; Diuretics; Heart Failure; Humans; Hydrochlorothiazide; Potassium; Spironolactone | 1962 |
Investigation of in vivo tracer techniques in drug screening studies.
Topics: Acetazolamide; Chlorothiazide; Diuretics; Drug Evaluation, Preclinical; Hydrochlorothiazide; Organomercury Compounds; Radiometry; Sodium; Spironolactone | 1963 |
"Intractable" ascites in cirrhosis: its management by a multiple diuretic approach.
Topics: Ascites; Bendroflumethiazide; Disease Management; Diuretics; Humans; Hydrochlorothiazide; Hydroxyprogesterones; Liver Cirrhosis; Prednisolone; Spironolactone | 1963 |
[Observations on nephrotic syndrome in adults].
Topics: Calcium; Humans; Hydrochlorothiazide; Nephrotic Syndrome; Penicillins; Potassium; Spironolactone; Triamcinolone | 1963 |
[EXPERIMENTAL STUDY OF THE DIURETIC EFFECT OF TRIAMTERENE].
Topics: Acetazolamide; Adrenalectomy; Body Fluids; Carbonic Anhydrases; Diuretics; Hydrochlorothiazide; Natriuresis; Pharmacology; Potassium; Pterins; Rats; Research; Spironolactone; Triamterene; Urine | 1963 |
[USE OF SPIRONOLACTONE IN THE THERAPY OF CONGESTIVE HEART FAILURE].
Topics: Body Fluids; Heart Failure; Humans; Hydrochlorothiazide; Potassium; Sodium; Sodium, Dietary; Spironolactone; Urine; Water-Electrolyte Balance | 1963 |
SPIRONOLACTONE IN ASCITES OF HEPATIC CIRRHOSIS: PRELIMINARY OBSERVATIONS.
Topics: Ascites; Ephedrine; Humans; Hydrochlorothiazide; Liver Cirrhosis; Spironolactone | 1963 |
[TREATMENT OF ASCITES IN HEPATIC CIRRHOSIS. 2].
Topics: Ascites; Dexamethasone; Diet, Sodium-Restricted; Hydrochlorothiazide; Liver Cirrhosis; Prognosis; Spironolactone; Water-Electrolyte Balance | 1963 |
[ON THE ANTIHYPERTENSIVE EFFECT OF THE SUBSTANCES ISOBUTYLHYDROCHLOROTHIAZIDE, SPIRONOLACTONE AND TRIAMTERENE ACTING ON ELECTROLYTES].
Topics: Antihypertensive Agents; Diuretics; Electrolytes; Geriatrics; Humans; Hydrochlorothiazide; Hypertension; Mineralocorticoid Receptor Antagonists; Pterins; Spironolactone; Triamterene | 1963 |
[DIURETIC THERAPY OF DECOMPENSATED HEPATIC CIRRHOSIS].
Topics: Blood Chemical Analysis; Chlorothiazide; Chlorthalidone; Diuresis; Diuretics; Electrolytes; Humans; Hydrochlorothiazide; Liver Cirrhosis; Mineralocorticoid Receptor Antagonists; Prednisone; Progesterone; Spironolactone; Urine | 1963 |
[FAMILIAL RENAL DIABETES INSIPIDUS. II].
Topics: Blood Chemical Analysis; Chlorides; Diabetes Insipidus; Diabetes Insipidus, Neurogenic; Diagnosis; Humans; Hydrochlorothiazide; Hypernatremia; Infant; Kidney; Spironolactone | 1963 |
ALDOSTERONE ANTAGONISTS IN DIURETIC THERAPY: THEIR EFFECT ON THE REFRACTORY PHASE.
Topics: Blood Chemical Analysis; Body Weight; Edema; Heart Failure; Hematocrit; Hydrochlorothiazide; Mineralocorticoid Receptor Antagonists; Pterins; Spironolactone; Triamterene | 1964 |
[CLINICAL RESEARCH ON A NEW DIURETIC: TRIAMTERENE].
Topics: Ascites; Diabetes Insipidus; Diuretics; Edema; Humans; Hydrochlorothiazide; Hyperaldosteronism; Liver Cirrhosis; Multiple Myeloma; Pterins; Spironolactone; Triamterene; Water-Electrolyte Balance | 1963 |
"REFRACTORY" ASCITES OF CIRRHOSIS: NEWER THERAPEUTIC PROCEDURES.
Topics: Ascites; Bendroflumethiazide; Humans; Hydrochlorothiazide; Liver Cirrhosis; Prednisone; Spironolactone | 1964 |
MEMBRANOUS GLOMERULONEPHRITIS: DISCUSSION AND CASE PRESENTATION.
Topics: Adolescent; Adrenocorticotropic Hormone; Biopsy; Cortisone; Diagnosis; Electrons; Glomerulonephritis; Glomerulonephritis, Membranous; Hydrochlorothiazide; Microscopy; Microscopy, Electron; Pathology; Prednisone; Spironolactone; Therapeutics | 1964 |
[EFFECTS OF HYDROCHLOROTHIAZIDE ASSOCIATED WITH ALDOSTERONE ANTAGONISTS IN THE THERAPY OF INFANTILE NEPHROTIC EDEMA. II. STUDY OF OSMOLAR CLEARANCES AND FREE WATER].
Topics: Child; Diuresis; Edema; Glomerulonephritis; Humans; Hydrochlorothiazide; Ketones; Kidney Function Tests; Metabolism; Metyrapone; Mineralocorticoid Receptor Antagonists; Nephrosis; Nephrotic Syndrome; Osmosis; Sodium; Spironolactone; Water; Water-Electrolyte Balance | 1963 |
[EFFECTS OF HYDROCHLOROTHIAZIDE ASSOCIATED WITH ALDOSTERONE IN THE THERAPY OF NEPHROTIC EDEMA. I. CLINICAL RESULTS AND STUDY OF WATER AND SALT METABOLISM IN 3 CASES].
Topics: Adrenocorticotropic Hormone; Aldosterone; Child; Edema; Glomerulonephritis; Humans; Hydrochlorothiazide; Metabolism; Mineralocorticoid Receptor Antagonists; Nephrosis; Nephrotic Syndrome; Prednisolone; Sodium Chloride; Spironolactone; Water; Water-Electrolyte Balance | 1963 |
[NATRIURETIC DRUGS].
Topics: Acetazolamide; Aldosterone; Ascites; Chlorothiazide; Dexamethasone; Diabetes Insipidus; Diuresis; Diuretics; Heart Failure; Hydrochlorothiazide; Hydroflumethiazide; Hypertension; Kidney Tubules; Metyrapone; Mineralocorticoid Receptor Antagonists; Natriuresis; Pharmacology; Physiology; Spironolactone; Sulfanilamide; Sulfanilamides; Thiazines | 1963 |
[THE TREATMENT OF EDEMA WITH SULFONAMIDE DIURETICS].
Topics: Acetazolamide; Acidosis; Benzothiadiazines; Chlorothiazide; Chlorthalidone; Dehydration; Diuretics; Edema; Heart Failure; Hepatic Encephalopathy; Humans; Hydrochlorothiazide; Hyperaldosteronism; Hypokalemia; Hyponatremia; Kidney Diseases; Liver Cirrhosis; Spironolactone; Sulfonamides; Toxicology; Triamterene | 1964 |
[ON THE EFFECT OF SALI-DIURETICS IN DIABETES INSIPIDUS].
Topics: Acetazolamide; Adolescent; Chlorthalidone; Diabetes Insipidus; Diabetes Insipidus, Neurogenic; Diuretics; Hydrochlorothiazide; Kidney Function Tests; Pharmacology; Spironolactone; Vasopressins; Water-Electrolyte Balance | 1964 |
[PHARMACOLOGICAL ACTIONS OF 2 HETEROCYCLIC GLYOXYLIC ALDEHYDES WITH NOTABLE DIURETIC ACTIVITY].
Topics: Aldehydes; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chlorothiazide; Coumarins; Diuretics; Electrolytes; Hepatitis; Hepatitis A; Hydrochlorothiazide; Pharmacology; Rats; Research; Spironolactone; Urine | 1964 |
CHEMOTHERAPY OF COLON CANCER.
Topics: Androgens; Colonic Neoplasms; Cortisone; Floxuridine; Fluorouracil; Hydrochlorothiazide; Pyrimidines; Spironolactone; Toxicology | 1964 |
MINERALOCORTICOID-BLOCKING PROPERTIES OF A PROGESTERONE-LIKE DERIVATIVE (SC-11835).
Topics: Adrenal Cortex Hormones; Adrenalectomy; Aldosterone; Animals; Desoxycorticosterone; Dogs; Hydrochlorothiazide; Kidney; Metabolism; Mineralocorticoids; Pharmacology; Potassium; Progesterone; Progestins; Rats; Research; Sodium; Spironolactone; Urine | 1964 |
[OBSERVATIONS ON THE CLINICAL USE OF TRIAMTERENE IN TREATMENT OF THE ASCITES OF HEPATIC CIRRHOSIS].
Topics: Ascites; Diuretics; Humans; Hydrochlorothiazide; Liver Cirrhosis; Pterins; Spironolactone; Triamterene | 1964 |
[THE INTRODUCTION OF ALDOSTERONE ANTAGONISTS IN THERAPY].
Topics: Chlorthalidone; Edema; Humans; Hydrochlorothiazide; Hydroflumethiazide; Mineralocorticoid Receptor Antagonists; Spironolactone | 1964 |
[AUTOPERFUSION OF ASCITIC FLUID AND DIURETIC TREATMENT IN PREPARATION FOR SURGERY IN CIRRHOTIC PATIENTS].
Topics: Ascites; Ascitic Fluid; Diet, Sodium-Restricted; Diuretics; Humans; Hydrochlorothiazide; Liver Cirrhosis; Preoperative Care; Pterins; Spironolactone; Triamterene; Water-Electrolyte Balance | 1964 |
CLINICAL EXPERIENCE WITH A NEW DIURETIC, TRIAMTERENE, IN CONJESTIVE HEART FAILURE.
Topics: Arrhythmias, Cardiac; Canada; Chlorides; Digitalis Glycosides; Diuretics; Edema; Heart Failure; Hydrochlorothiazide; Hypokalemia; Ion Exchange; Pharmacology; Potassium; Sodium; Spironolactone; Toxicology; Triamterene; Urine | 1964 |
A NEW EFFECTIVE DIURETIC--LASIX.
Topics: Chlorthalidone; Diuretics; Drug Therapy; Furosemide; Heart Failure; Hydrochlorothiazide; Hypokalemia; Injections, Intravenous; Liver Cirrhosis; Potassium; Pulmonary Edema; Sodium; Sodium, Dietary; Spironolactone; Toxicology; Urine | 1964 |
THE PERIODIC PARALYSES: DIFFERENTIAL FEATURES AND PATHOLOGICAL OBSERVATIONS IN PERMANENT MYOPATHIC WEAKNESS.
Topics: Acetazolamide; Drug Therapy; Epinephrine; Humans; Hydrochlorothiazide; Hydrocortisone; Hyperkalemia; Hypokalemia; Insulin; Muscular Diseases; Muscular Dystrophies; Paralyses, Familial Periodic; Paralysis; Pathology; Potassium; Spironolactone; Water-Electrolyte Balance | 1964 |
[ON MODIFICATIONS OF PLASMA AND URINARY ELECTROLYTES IN ASCITOGENIC HEPATIC CIRRHOSIS IN TREATMENT WITH TRIAMTERENE ALONE AND ASSOCIATED WITH HYDROCHLOROTHIAZIDE AND WITH SPIRONOLACTONE].
Topics: Ascites; Biomedical Research; Chlorides; Electrolytes; Geriatrics; Humans; Hydrochlorothiazide; Liver Cirrhosis; Plasma; Potassium; Sodium; Sodium, Dietary; Spironolactone; Triamterene; Urine; Water-Electrolyte Balance | 1964 |
FETAL ASCITES--LIVER GIANT-CELL TRANSFORMATION. REPORT OF A CASE WITH RECOVERY.
Topics: Ascites; Biopsy; Drainage; Exchange Transfusion, Whole Blood; Fetal Diseases; Humans; Hydrochlorothiazide; Infant; Infant, Newborn; Infant, Newborn, Diseases; Liver; Liver Diseases; Pathology; Serum Albumin; Spironolactone | 1964 |
[POST-TRAUMATIC DIABETES INSIPIDUS AND ITS TREATMENT].
Topics: Adolescent; Arginine Vasopressin; Diabetes Insipidus; Diabetes Insipidus, Neurogenic; Drug Therapy; Humans; Hydrochlorothiazide; Spironolactone; Vasopressins; Wounds and Injuries | 1964 |
THE EFFECT OF DIURETICS ON THE ADRENAL CORTEX OF THE RAT.
Topics: Acetazolamide; Adrenal Cortex; Adrenal Glands; Ascorbic Acid; Body Weight; Cholesterol; Diuretics; Hydrochlorothiazide; Organomercury Compounds; Pharmacology; Rats; Research; Spironolactone | 1964 |
METABOLIC STUDIES WITH THE DIURETIC TRIAMTERENE IN PATIENTS WITH CIRRHOSIS AND ASCITES.
Topics: Ammonia; Ascites; Blood; Carbon Dioxide; Chlorides; Creatine; Creatinine; Diuresis; Diuretics; Drug Synergism; Humans; Hydrochlorothiazide; Hydrogen-Ion Concentration; Liver Cirrhosis; Metabolism; Natriuresis; Pharmacology; Potassium; Sodium; Sodium, Dietary; Spironolactone; Toxicology; Triamterene; Urine | 1964 |
ETHACRYNIC ACID: A NEW POTENT DIURETIC.
Topics: Alkalosis; Blood Chemical Analysis; Blood Urea Nitrogen; Body Weight; Digitalis Glycosides; Diuresis; Diuretics; Drug Therapy; Ethacrynic Acid; Geriatrics; Heart Failure; Hodgkin Disease; Humans; Hydrochlorothiazide; Organomercury Compounds; Pharmacology; Spironolactone; Toxicology; Uremia; Water-Electrolyte Balance | 1965 |
FURTHER EXPERIENCE WITH SPIRONOLACTONE-HYDRO-CHLOROTHIAZIDE (ALDACTAZIDE-A) IN THE LONG-TERM TREATMENT OF REFRACTORY CARDIAC EDEMA.
Topics: Arteriosclerosis; Chlorothiazide; Coronary Disease; Drug Combinations; Drug Therapy; Edema; Edema, Cardiac; Geriatrics; Heart Failure; Hydrochlorothiazide; Hypertension; Spironolactone | 1965 |
LUPUS GLOMERULONEPHRITIS. THE EFFECT OF LARGE DOSES OF CORTICOSTEROIDS ON RENAL FUNCTION AND RENAL LESIONS IN TWO CHILDREN.
Topics: Adolescent; Adrenal Cortex Hormones; Cortisone; Drug Therapy; Glomerulonephritis; Guanethidine; Hydralazine; Hydrochlorothiazide; Kidney Function Tests; Lupus Erythematosus, Systemic; Lupus Nephritis; Methantheline; Pathology; Prednisone; Propantheline; Quaternary Ammonium Compounds; Reserpine; Spironolactone; Triamcinolone | 1965 |
[ON THE COMBINATION OF SPIRONOLACTONE AND METOPIRONE IN THE TREATMENT OF DECOMPENSATED LIVER CIRRHOSIS].
Topics: Dexamethasone; Drug Therapy; Hydrochlorothiazide; Ketones; Liver Cirrhosis; Metyrapone; Mineralocorticoid Receptor Antagonists; Spironolactone | 1964 |
Influence of spironolactone in modifying the renal electrolyte effects of hydrochlorothiazide in laboratory animals.
Topics: Aldosterone; Animals; Animals, Laboratory; Chlorothiazide; Electrolytes; Hydrochlorothiazide; Kidney; Mineralocorticoid Receptor Antagonists; Potassium; Sodium; Spironolactone | 1962 |
Spectophotometric quantitative resolution of hydrochlorothiazide and spironolactone in tablets by chemometric analysis methods.
Topics: Hydrochlorothiazide; Linear Models; Models, Chemical; Multivariate Analysis; Spectrophotometry, Ultraviolet; Spironolactone; Tablets, Enteric-Coated | 2003 |
Continuous wavelet transformation applied to the simultaneous quantitative analysis of two-component mixtures.
Topics: Algorithms; Calibration; Chemistry, Pharmaceutical; Data Interpretation, Statistical; Diuretics; Drug Combinations; Hydrochlorothiazide; Pharmaceutical Preparations; Reference Standards; Regression Analysis; Reproducibility of Results; Solutions; Spironolactone; Tablets | 2004 |
Bone loss in rats with aldosteronism.
Topics: Animals; Bone Resorption; Calcium; Hydrochlorothiazide; Hyperaldosteronism; Magnesium; Male; Parathyroid Hormone; Potassium; Rats; Rats, Sprague-Dawley; Spironolactone | 2005 |
Potent diuretic effects of prednisone in heart failure patients with refractory diuretic resistance.
Topics: Creatinine; Diuresis; Diuretics; Female; Furosemide; Glomerular Filtration Rate; Glucocorticoids; Heart Failure; Humans; Hydrochlorothiazide; Kidney; Male; Middle Aged; Prednisone; Prospective Studies; Spironolactone; Treatment Outcome | 2007 |
Hypertension induces somatic cellular senescence in rats and humans by induction of cell cycle inhibitor p16INK4a.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Genetically Modified; Antihypertensive Agents; Blood Pressure; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p16; Desoxycorticosterone; Heart Ventricles; Humans; Hydralazine; Hydrochlorothiazide; Hypertension, Renal; Kidney; Losartan; Mice; Mineralocorticoid Receptor Antagonists; Nephrosclerosis; p38 Mitogen-Activated Protein Kinases; Rats; Renin; Reserpine; RNA, Messenger; Spironolactone | 2008 |
Blood pressure versus direct mineralocorticoid effects on kidney inflammation and fibrosis in DOCA-salt hypertension.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Desoxycorticosterone; Disease Models, Animal; Disease Progression; Diuretics; Dose-Response Relationship, Drug; Glomerulonephritis; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Mineralocorticoid Receptor Antagonists; Mineralocorticoids; Nephrosclerosis; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reserpine; Spironolactone | 2008 |
Spironolactone and hydrochlorothiazide exert antioxidant effects and reduce vascular matrix metalloproteinase-2 activity and expression in a model of renovascular hypertension.
Topics: Animals; Antioxidants; Aorta; Blood Pressure; Drug Therapy, Combination; Hydrochlorothiazide; Hypertension, Renovascular; In Vitro Techniques; Lipid Peroxides; Matrix Metalloproteinase 2; Muscle, Smooth, Vascular; Oxidative Stress; Rats; Reactive Oxygen Species; Spironolactone; Vasodilation | 2010 |
Spectrophotometric and chemometric determination of hydrochlorothiazide and spironolactone in binary mixture in the presence of their impurities and degradants.
Topics: Algorithms; Antihypertensive Agents; Chemistry, Pharmaceutical; Drug Combinations; Hydrochlorothiazide; Spectrophotometry; Spironolactone; Tablets | 2010 |
Validated chromatographic methods for determination of hydrochlorothiazide and spironolactone in pharmaceutical formulation in presence of impurities and degradants.
Topics: Chemistry, Pharmaceutical; Chromatography, Liquid; Drug Contamination; Drug Stability; Hydrochlorothiazide; Linear Models; Reproducibility of Results; Sensitivity and Specificity; Spironolactone; Tablets | 2011 |
Activation of thiazide-sensitive co-transport by angiotensin II in the cyp1a1-Ren2 hypertensive rat.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cytochrome P-450 CYP1A1; Hydrochlorothiazide; Hypertension; Kidney Tubules, Distal; Losartan; Male; Microvessels; Natriuresis; Rats; Rats, Transgenic; Renin; Sodium Chloride Symporters; Spironolactone | 2012 |
Patient with purulent pericarditis: a case doomed to fail?
Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Carvedilol; Diuretics; Drainage; Echocardiography; Fatal Outcome; Furosemide; Humans; Hydrochlorothiazide; Infusions, Intravenous; Male; Mediastinitis; Middle Aged; Pericarditis; Propanolamines; Sclerosis; Spironolactone; Suppuration; Vitamin K | 2013 |
Commentary in support of a highly effective hypertension treatment algorithm.
Topics: Adult; Algorithms; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Combinations; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Lisinopril; Spironolactone; Treatment Outcome; United States | 2013 |
Effects of three commonly-used diuretics on the urinary proteome.
Topics: Animals; Biomarkers; Chromatography, Liquid; Diuretics; Furosemide; Humans; Hydrochlorothiazide; Male; Metabolic Networks and Pathways; Proteome; Rats; Rats, Sprague-Dawley; Spironolactone; Tandem Mass Spectrometry | 2014 |
Diuretic exposure in premature infants from 1997 to 2011.
Topics: Acetazolamide; Amiloride; Bronchopulmonary Dysplasia; Chlorothiazide; Cohort Studies; Diazoxide; Diuretics; Drug Therapy, Combination; Ethacrynic Acid; Female; Furosemide; Humans; Hydrochlorothiazide; Infant, Extremely Premature; Infant, Newborn; Infant, Premature; Male; Mannitol; Metolazone; Off-Label Use; Respiration, Artificial; Retrospective Studies; Spironolactone; Thrombocytopenia | 2015 |
If I had resistant hypertension.
Topics: Amlodipine; Antihypertensive Agents; Atorvastatin; Blood Pressure; Dose-Response Relationship, Drug; Drug Resistance; Drug Therapy, Combination; Heptanoic Acids; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Pyrroles; Spironolactone; Tetrazoles; Treatment Failure; Treatment Outcome | 2014 |
Regulation of myogenic tone and structure of parenchymal arterioles by hypertension and the mineralocorticoid receptor.
Topics: Animals; Antihypertensive Agents; Arterioles; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cerebrovascular Circulation; Cerebrum; Compliance; Eplerenone; Hydralazine; Hydrochlorothiazide; Hypertension; Middle Cerebral Artery; Mineralocorticoid Receptor Antagonists; Muscle Tonus; Muscle, Smooth, Vascular; Nifedipine; Organ Size; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Mineralocorticoid; Reserpine; Spironolactone; Vascular Remodeling; Vascular Stiffness | 2015 |
Does this patient have hypertensive encephalopathy?
Topics: Amlodipine; Antihypertensive Agents; Biphenyl Compounds; Brain; Carbazoles; Carvedilol; Computed Tomography Angiography; Confusion; Creatinine; Electrocardiography; Glomerular Filtration Rate; Hallucinations; Headache; Heart; Humans; Hydrochlorothiazide; Hypertension; Hypertensive Encephalopathy; Irbesartan; Magnetic Resonance Imaging; Male; Middle Aged; Propanolamines; Renal Artery Obstruction; Spironolactone; Tetrazoles; Ultrasonography | 2016 |
Trends in Antihypertensive Medication Use Among US Patients With Resistant Hypertension, 2008 to 2014.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure Determination; Calcium Channel Blockers; Chlorthalidone; Cohort Studies; Drug Resistance; Drug Therapy, Combination; Drug Utilization; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Patient Safety; Retrospective Studies; Risk Assessment; Severity of Illness Index; Spironolactone; Treatment Outcome; United States | 2016 |
Applications of shun shell column and nanocomposite sorbent for analysis of eleven anti-hypertensive in human plasma.
Topics: Adsorption; Antihypertensive Agents; Chromatography, High Pressure Liquid; Diltiazem; Furosemide; Humans; Hydrochlorothiazide; Irbesartan; Iron; Labetalol; Limit of Detection; Losartan; Metal Nanoparticles; Methyldopa; Nanocomposites; Polyvinyl Alcohol; Prazosin; Propranolol; Reproducibility of Results; Solid Phase Microextraction; Spironolactone; Valsartan | 2020 |
Furosemide and spironolactone doses and hyponatremia in patients with heart failure.
Topics: Aged; Aged, 80 and over; Diuretics; Female; Furosemide; Heart Failure; Hospitalization; Humans; Hydrochlorothiazide; Hyponatremia; Male; Middle Aged; Spironolactone | 2020 |
Effect of preload reducing therapy on right ventricular size and function in patients with arrhythmogenic right ventricular cardiomyopathy.
Topics: Adult; Arrhythmogenic Right Ventricular Dysplasia; Dose-Response Relationship, Drug; Drug Combinations; Echocardiography, Doppler; Female; Follow-Up Studies; Heart Ventricles; Humans; Hydrochlorothiazide; Isosorbide Dinitrate; Male; Middle Aged; Organ Size; Retrospective Studies; Spironolactone; Stroke Volume; Time Factors; Vasodilator Agents; Ventricular Function, Right | 2021 |
The impact of different diuretics on regression of myocardial reperfusion injury in spontaneously hypertensive rats.
Topics: Animals; Diuretics; Hydrochlorothiazide; Indapamide; Ischemia; Male; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Spironolactone | 2023 |