spironolactone has been researched along with flutamide in 64 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (9.38) | 18.7374 |
| 1990's | 17 (26.56) | 18.2507 |
| 2000's | 21 (32.81) | 29.6817 |
| 2010's | 19 (29.69) | 24.3611 |
| 2020's | 1 (1.56) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Bellavance, E; Luu-The, V; Poirier, D | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Huben, RP | 1 |
| Cantabrana, B; Garcia Valencia, V; Gutierrez, M; Hidalgo, A; Sanchez, M | 1 |
| Concolino, G; Di Silverio, F; Sciarra, F; Toscano, V | 1 |
| Cusan, L; Labrie, C; Labrie, F; Lapointe, S; Plante, M | 1 |
| Namer, M | 1 |
| Begin, DJ; Labrie, F; Luthy, IA | 1 |
| Mowszowicz, I | 1 |
| Combettes, C; Durand-Seme, V; Leveque, JL; Querleux, B; Saint-Leger, D | 1 |
| Fair, WR; Sogani, PC | 1 |
| Malchoff, CD; Malchoff, DM; Reardon, G | 1 |
| Erenus, M | 1 |
| Demirçay, Z; Durmuşoğlu, F; Erenus, M; Gürbüz, O; Pekin, S | 1 |
| Cusan, L; Dupont, A; Gomez, JL; Labrie, F; Tremblay, RR | 1 |
| Brun, E; Caputo, M; Castello, R; Furlani, L; Magnani, CM; Moghetti, P; Muggeo, M; Negri, C; Tosi, F | 1 |
| Shaw, JC | 1 |
| Cutler, GB; Merke, DP | 1 |
| Wilson, L; Zemtsov, A | 1 |
| Schmidt, JB | 1 |
| Sinclair, R; Young, R | 1 |
| Adami, S; Castello, R; Gatti, D; Moghetti, P; Muggeo, M; Negri, C; Rossini, M; Tosi, F; Zamberlan, N | 1 |
| Rittmaster, RS | 1 |
| Durmuşoğlu, F; Erenus, M; Gürbüz, O; Yücelten, D | 1 |
| Kocijancic, A; Prezelj, J | 1 |
| Castello, R; Dorizzi, R; Fortunato, A; Moghetti, P; Muggeo, M; Negri, C; Spiazzi, GG; Tosi, F | 1 |
| Caputo, M; Castello, R; Misciali, C; Moghetti, P; Muggeo, M; Negri, C; Perrone, F; Tosi, F; Tosti, A | 1 |
| Holst, M; Ritzén, EM; Svechnikov, K | 1 |
| Drapier-Faure, E; Faure, M | 1 |
| Ajossa, S; Guerriero, S; Melis, GB; Orrù, M; Paoletti, AM | 1 |
| Kelestimur, F; Sahin, Y | 1 |
| Tan, J | 1 |
| Haroun, M | 1 |
| Al-Inany, H | 2 |
| Inal, MM; Taner, CE; Yildirim, Y | 1 |
| Conway, GS; Koulouri, O | 1 |
| Aral, Y; Bavbek, N; Culha, C; Demirbas, B; Güler, S; Karakurt, F; Sahin, I; Serter, R | 1 |
| Scheinfeld, N | 1 |
| Clarke, S; George, R; Thiboutot, D | 1 |
| Bachelot, A; Chabbert-Buffet, N; Galand-Portier, MB; Kerlan, V; Salenave, S | 1 |
| Sinclair, R; Yazdabadi, A | 1 |
| Kamangar, F; Shinkai, K | 1 |
| Karaca, Z; Kelestimur, F; Unluhizarci, K | 1 |
| Buzney, C; Buzney, E; Reynolds, RV; Sheu, J | 1 |
| Bechtel, MA; Harfmann, KL | 1 |
| Bettoli, V; Virgili, A; Zauli, S | 1 |
| Carter, B; Fedorowicz, Z; Pandis, N; van Zuuren, EJ | 1 |
| Ioannides, D; Lazaridou, E | 1 |
| Al Khalifah, RA; Bassilious, E; Dennis, B; Flórez, ID; Neupane, B; Thabane, L | 1 |
| Fedorowicz, Z; van Zuuren, EJ | 1 |
| Chahal, DS; Hassoun, LA; Larsen, LN; Sivamani, RK | 1 |
| Azarchi, S; Bienenfeld, A; Lo Sicco, K; Marchbein, S; Nagler, AR; Shapiro, J | 1 |
| Hsiao, JL; Jeong, C; Masson, R; Shi, VY; Shih, T | 1 |
28 review(s) available for spironolactone and flutamide
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Clinical applications of antiandrogens.
Topics: Androgen Antagonists; Breast Neoplasms; Cyproterone; Cyproterone Acetate; Female; Flutamide; Humans; Imidazoles; Imidazolidines; Male; Prostatic Hyperplasia; Prostatic Neoplasms; Puberty, Precocious; Skin Diseases; Spironolactone | 1988 |
[Antiandrogens. Mechanisms and paradoxical effects].
Topics: 5-alpha Reductase Inhibitors; Androgen Antagonists; Androgens; Anilides; Cimetidine; Cyproterone; Cyproterone Acetate; Flutamide; Humans; Nitriles; Spironolactone; Tosyl Compounds | 1989 |
Treatment of advanced prostatic cancer.
Topics: Adrenalectomy; Aminoglutethimide; Androgen Antagonists; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Combined Modality Therapy; Cyproterone; Cyproterone Acetate; Estrogens; Flutamide; Glucocorticoids; Humans; Ketoconazole; Male; Megestrol; Megestrol Acetate; Orchiectomy; Pituitary Hormone-Releasing Hormones; Prostatic Neoplasms; Spironolactone; Time Factors | 1987 |
Antiandrogen therapy in dermatology.
Topics: Adrenal Cortex Hormones; Androgen Antagonists; Cimetidine; Contraceptives, Oral; Cyproterone Acetate; Finasteride; Flutamide; Humans; Ketoconazole; Skin Diseases; Spironolactone | 1996 |
Hirsutes. II: Treatment.
Topics: 5-alpha Reductase Inhibitors; Androgen Antagonists; Androgen Receptor Antagonists; Contraceptives, Oral; Cosmetics; Cyproterone Acetate; Enzyme Inhibitors; Female; Finasteride; Flutamide; Glucocorticoids; Gonadotropin-Releasing Hormone; Hair Removal; Hirsutism; Humans; Laser Therapy; Mineralocorticoid Receptor Antagonists; Prednisolone; Spironolactone | 1998 |
Antiandrogen treatment of polycystic ovary syndrome.
Topics: Alopecia; Androgen Antagonists; Androgens; Cyproterone Acetate; Female; Finasteride; Flutamide; Hirsutism; Humans; Polycystic Ovary Syndrome; Spironolactone | 1999 |
[What is the role of hormonal treatments in acne?].
Topics: Acne Vulgaris; Androgen Antagonists; Cyproterone; Estrogens; Flutamide; Glucocorticoids; Hormone Antagonists; Humans; Mineralocorticoid Receptor Antagonists; Nandrolone; Patient Selection; Progestins; Spironolactone; Treatment Outcome | 2001 |
Medical treatment regimens of hirsutism.
Topics: Androgen Antagonists; Cyproterone Acetate; Drug Combinations; Enzyme Inhibitors; Ethinyl Estradiol; Female; Finasteride; Flutamide; Hirsutism; Humans; Hypoglycemic Agents; Metformin; Mineralocorticoid Receptor Antagonists; Spironolactone | 2004 |
Hormonal treatment of acne: review of current best evidence.
Topics: Acne Vulgaris; Androgen Antagonists; Contraceptives, Oral, Hormonal; Female; Flutamide; Humans; Male; Spironolactone; Treatment Outcome | 2004 |
Hormonal therapy of acne.
Topics: Acne Vulgaris; Adult; Androgen Antagonists; Androgens; Contraceptives, Oral, Hormonal; Cyproterone Acetate; Female; Flutamide; Humans; Middle Aged; Spironolactone | 2004 |
Polycystic ovary syndrome.
Topics: Androgen Antagonists; Cyproterone Acetate; Drug Therapy, Combination; Ethinyl Estradiol; Female; Finasteride; Flutamide; Hirsutism; Humans; Metformin; Polycystic Ovary Syndrome; Spironolactone | 2004 |
Polycystic ovary syndrome.
Topics: Cyproterone Acetate; Drug Therapy, Combination; Ethinyl Estradiol; Female; Finasteride; Flutamide; Humans; Metformin; Polycystic Ovary Syndrome; Spironolactone | 2005 |
A systematic review of commonly used medical treatments for hirsutism in women.
Topics: Androgen Antagonists; Contraceptives, Oral, Hormonal; Cyproterone Acetate; Drug Therapy, Combination; Female; Finasteride; Flutamide; Hirsutism; Humans; Metformin; Spironolactone; Thiazolidinediones; Treatment Outcome | 2008 |
A review of hormonal therapy for female pattern (androgenic) alopecia.
Topics: 5-alpha Reductase Inhibitors; Alopecia; Androgen Antagonists; Androgens; Cyproterone Acetate; Dermatologic Agents; Enzyme Inhibitors; Female; Finasteride; Flutamide; Humans; Minoxidil; Spironolactone; Testosterone | 2008 |
Hormonal therapy for acne.
Topics: Acne Vulgaris; Androgen Antagonists; Contraceptives, Oral; Cyproterone Acetate; Female; Flutamide; Humans; Mineralocorticoid Receptor Antagonists; Spironolactone | 2008 |
Anti-androgen treatments.
Topics: Androgen Antagonists; Cyproterone Acetate; Estrogens; Female; Finasteride; Flutamide; Gonadotropin-Releasing Hormone; Hirsutism; Humans; Hyperandrogenism; Mineralocorticoid Receptor Antagonists; Progestins; Spironolactone | 2010 |
Acne in the adult female patient: a practical approach.
Topics: Acne Vulgaris; Adolescent; Adult; Androgen Antagonists; Contraceptives, Oral, Hormonal; Dermatologic Agents; Female; Flutamide; Humans; Male; Polycystic Ovary Syndrome; Pregnancy; Spironolactone; Young Adult | 2012 |
Polycystic ovary syndrome: a review for dermatologists: Part II. Treatment.
Topics: 5-alpha Reductase Inhibitors; Acne Vulgaris; Alopecia; Androgen Antagonists; Contraceptives, Oral, Combined; Dermatology; Female; Finasteride; Flutamide; Hirsutism; Humans; Hypoglycemic Agents; Life Style; Metformin; Mineralocorticoid Receptor Antagonists; Polycystic Ovary Syndrome; Spironolactone; Thiazolidinediones | 2014 |
Hair loss in women.
Topics: 5-alpha Reductase Inhibitors; Alopecia; Androgen Antagonists; Female; Finasteride; Flutamide; Hair; Humans; Hypotrichosis; Minoxidil; Phototherapy; Spironolactone; Vasodilator Agents | 2015 |
Is hormonal treatment still an option in acne today?
Topics: Acne Vulgaris; Adrenal Cortex Hormones; Adult; Androgen Antagonists; Contraceptives, Oral, Hormonal; Cyproterone Acetate; Female; Flutamide; Gonadotropin-Releasing Hormone; Hormones; Humans; Hyperandrogenism; Spironolactone | 2015 |
Interventions for hirsutism (excluding laser and photoepilation therapy alone).
Topics: 5-alpha Reductase Inhibitors; Adult; Androgen Antagonists; Body Mass Index; Contraceptive Agents, Female; Cyproterone Acetate; Desogestrel; Drug Combinations; Eflornithine; Ethinyl Estradiol; Female; Finasteride; Flutamide; Hirsutism; Humans; Hypoglycemic Agents; Metformin; Quality of Life; Randomized Controlled Trials as Topic; Spironolactone | 2015 |
Female pattern hair loss.
Topics: 5-alpha Reductase Inhibitors; Administration, Cutaneous; Alopecia; Androgen Antagonists; Androgen Receptor Antagonists; Antifungal Agents; Cyproterone Acetate; Dutasteride; Female; Finasteride; Flutamide; Hair; Humans; Ketoconazole; Minoxidil; Postmenopause; Spironolactone; Vasodilator Agents | 2015 |
The effectiveness and safety of treatments used for polycystic ovarian syndrome management in adolescents: a systematic review and network meta-analysis protocol.
Topics: Adolescent; Androgen Antagonists; Contraceptives, Oral; Diet; Drug Therapy, Combination; Exercise; Female; Flutamide; Humans; Hypoglycemic Agents; Life Style; Metformin; Mineralocorticoid Receptor Antagonists; Pioglitazone; Polycystic Ovary Syndrome; Research Design; Spironolactone; Systematic Reviews as Topic; Thiazolidinediones; Young Adult | 2015 |
Interventions for hirsutism excluding laser and photoepilation therapy alone: abridged Cochrane systematic review including GRADE assessments.
Topics: 5-alpha Reductase Inhibitors; Adolescent; Androgen Antagonists; Body Mass Index; Contraceptives, Oral; Cyproterone Acetate; Drug Therapy, Combination; Female; Finasteride; Flutamide; Gonadotropin-Releasing Hormone; Hirsutism; Humans; Hyperandrogenism; Hypoglycemic Agents; Polycystic Ovary Syndrome; Quality of Life; Randomized Controlled Trials as Topic; Risk Reduction Behavior; Spironolactone; Treatment Outcome; Young Adult | 2016 |
The use of hormonal agents in the treatment of acne.
Topics: Acne Vulgaris; Administration, Oral; Contraceptive Agents; Cortodoxone; Cyproterone Acetate; Dermatologic Agents; Female; Finasteride; Flutamide; Hormones; Humans; Male; Meta-Analysis as Topic; Mineralocorticoid Receptor Antagonists; Propionates; Spironolactone; Treatment Outcome | 2016 |
Androgens in women: Hormone-modulating therapies for skin disease.
Topics: 5-alpha Reductase Inhibitors; Acne Vulgaris; Adrenal Hyperplasia, Congenital; Alopecia; Androgen Antagonists; Androgens; Contraceptives, Oral, Combined; Dutasteride; Female; Finasteride; Flutamide; Hirsutism; Humans; Polycystic Ovary Syndrome; Receptors, Androgen; Spironolactone | 2019 |
Hormonal Treatments in Hidradenitis Suppurativa: A Systematic Review.
Topics: Finasteride; Flutamide; Hidradenitis Suppurativa; Humans; Liraglutide; Metformin; Spironolactone | 2023 |
12 trial(s) available for spironolactone and flutamide
| Article | Year |
|---|---|
Hormone therapy of prostatic bone metastases.
Topics: Actuarial Analysis; Androgen Antagonists; Bone Neoplasms; Combined Modality Therapy; Diethylstilbestrol; Estrogens; Flutamide; Gonadotropin-Releasing Hormone; Goserelin; Humans; Ketoconazole; Leuprolide; Male; Neoplasms, Hormone-Dependent; Orchiectomy; Prostatic Neoplasms; Remission Induction; Spironolactone; Survival Rate | 1992 |
Antiandrogens: clinical applications.
Topics: Acne Vulgaris; Adult; Androgen Antagonists; Cyproterone; Cyproterone Acetate; Dermatitis, Seborrheic; Female; Flutamide; Hirsutism; Humans; Male; Prostatic Neoplasms; Spironolactone | 1990 |
Treatment of advanced prostatic cancer.
Topics: Adrenalectomy; Aminoglutethimide; Androgen Antagonists; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Combined Modality Therapy; Cyproterone; Cyproterone Acetate; Estrogens; Flutamide; Glucocorticoids; Humans; Ketoconazole; Male; Megestrol; Megestrol Acetate; Orchiectomy; Pituitary Hormone-Releasing Hormones; Prostatic Neoplasms; Spironolactone; Time Factors | 1987 |
Efficacy of flutamide versus spironolactone.
Topics: Contraceptives, Oral; Female; Flutamide; Hirsutism; Humans; Incidence; Menstruation Disturbances; Spironolactone; Testosterone | 1995 |
Comparison of the efficacy of spironolactone versus flutamide in the treatment of hirsutism.
Topics: Adolescent; Adult; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Flutamide; Follicle Stimulating Hormone; Hirsutism; Humans; Luteinizing Hormone; Spironolactone; Testosterone | 1994 |
Comparison of flutamide and spironolactone in the treatment of hirsutism: a randomized controlled trial.
Topics: Adult; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Flutamide; Follicle Stimulating Hormone; Hirsutism; Humans; Luteinizing Hormone; Premenopause; Progesterone; Spironolactone; Testosterone | 1994 |
Spironolactone, but not flutamide, administration prevents bone loss in hyperandrogenic women treated with gonadotropin-releasing hormone agonist.
Topics: Adult; Bone and Bones; Bone Density; Bone Resorption; Female; Flutamide; Hirsutism; Humans; Polycystic Ovary Syndrome; Spironolactone; Triptorelin Pamoate | 1999 |
Recurrence rate of hirsutism after 3 different antiandrogen therapies.
Topics: Androgen Antagonists; Contraceptives, Oral; Cyproterone; Female; Flutamide; Hirsutism; Humans; Luteinizing Hormone; Recurrence; Spironolactone; Testosterone | 1999 |
Antiandrogen drugs lower serum prostate-specific antigen (PSA) levels in hirsute subjects: evidence that serum PSA is a marker of androgen action in women.
Topics: Adult; Androgen Antagonists; Androgens; Androstane-3,17-diol; Biomarkers; Double-Blind Method; Enzyme Inhibitors; Female; Finasteride; Flutamide; Hirsutism; Humans; Prostate-Specific Antigen; Spironolactone; Testosterone | 2000 |
Comparison of spironolactone, flutamide, and finasteride efficacy in the treatment of hirsutism: a randomized, double blind, placebo-controlled trial.
Topics: Adult; Androgen Antagonists; Double-Blind Method; Female; Finasteride; Flutamide; Hair; Hirsutism; Hormones; Humans; Mineralocorticoid Receptor Antagonists; Polycystic Ovary Syndrome; Spironolactone | 2000 |
Comparison of the clinical efficacy of flutamide and spironolactone plus Diane 35 in the treatment of idiopathic hirsutism: a randomized controlled study.
Topics: Adult; Androgen Antagonists; Cyproterone Acetate; Diuretics; Drug Combinations; Drug Therapy, Combination; Ethinyl Estradiol; Female; Flutamide; Hirsutism; Humans; Polycystic Ovary Syndrome; Prospective Studies; Spironolactone; Treatment Outcome | 2005 |
Comparison of the clinical efficacy of flutamide and spironolactone plus ethinyloestradiol/cyproterone acetate in the treatment of hirsutism: a randomised controlled study.
Topics: Adult; Androgen Antagonists; Cyproterone Acetate; Drug Combinations; Drug Therapy, Combination; Ethinyl Estradiol; Female; Flutamide; Hirsutism; Humans; Lipids; Prospective Studies; Spironolactone; Young Adult | 2008 |
25 other study(ies) available for spironolactone and flutamide
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Potent and selective steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 7, an enzyme that catalyzes the reduction of the key hormones estrone and dihydrotestosterone.
Topics: 17-Hydroxysteroid Dehydrogenases; Androstane-3,17-diol; Androstanes; Biocatalysis; Cell Line; Dihydrotestosterone; Enzyme Inhibitors; Estradiol; Estrone; Humans; Inhibitory Concentration 50; Oxidation-Reduction; Substrate Specificity | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Effects of steroidal and non-steroidal antiandrogens on the left atrium of the rat in vitro.
Topics: Androgen Antagonists; Animals; Calcium; Chlormadinone Acetate; Cimetidine; Cyproterone; Electric Stimulation; Female; Flutamide; Heart; Heart Atria; In Vitro Techniques; Male; Medroxyprogesterone; Myocardial Contraction; Rats; Rats, Inbred Strains; Spironolactone; Steroids; Stimulation, Chemical | 1991 |
Analysis of the androgenic activity of synthetic "progestins" currently used for the treatment of prostate cancer.
Topics: Adrenal Glands; Animals; Chlormadinone Acetate; Cyproterone; Cyproterone Acetate; Dihydrotestosterone; Flutamide; Male; Medroxyprogesterone; Medroxyprogesterone Acetate; Megestrol; Megestrol Acetate; Organ Size; Ornithine Decarboxylase; Progesterone Congeners; Prostate; Prostatic Neoplasms; Rats; Rats, Inbred Strains; Spironolactone | 1987 |
Androgenic activity of synthetic progestins and spironolactone in androgen-sensitive mouse mammary carcinoma (Shionogi) cells in culture.
Topics: Androgens; Animals; Cell Division; Chlormadinone Acetate; Dihydrotestosterone; Flutamide; Male; Mammary Neoplasms, Experimental; Medroxyprogesterone; Medroxyprogesterone Acetate; Megestrol; Mice; Progestins; Spironolactone; Tumor Cells, Cultured | 1988 |
Imaging the hamster flank organ by an ultrasonic technique: a new approach to animal tests.
Topics: Animals; Cricetinae; Cyproterone; Female; Flutamide; Male; Mesocricetus; Orchiectomy; Sebaceous Glands; Skin; Spironolactone; Testosterone; Ultrasonography | 1989 |
Glucocorticoid resistance.
Topics: Adrenal Gland Diseases; Amiloride; Child; Dexamethasone; Drug Resistance; Flutamide; Glucocorticoids; Humans; Male; Receptors, Glucocorticoid; Spironolactone | 1994 |
The insulin resistance in women with hyperandrogenism is partially reversed by antiandrogen treatment: evidence that androgens impair insulin action in women.
Topics: Adult; Androgen Antagonists; Androgens; Buserelin; Female; Flutamide; Glucose Clamp Technique; Humans; Hyperandrogenism; Insulin; Insulin Resistance; Ovulation; Spironolactone | 1996 |
New approaches to the treatment of congenital adrenal hyperplasia.
Topics: Adrenal Hyperplasia, Congenital; Age Determination by Skeleton; Androgen Antagonists; Child; Cyproterone; Drug Therapy, Combination; Female; Fludrocortisone; Flutamide; Growth; Humans; Hydrocortisone; Mineralocorticoid Receptor Antagonists; Spironolactone; Testolactone | 1997 |
Successful treatment of hirsutism in HAIR-AN syndrome using flutamide, spironolactone, and birth control therapy.
Topics: Acanthosis Nigricans; Adolescent; Androgen Antagonists; Contraceptives, Oral, Combined; Contraceptives, Oral, Synthetic; Drug Combinations; Drug Therapy, Combination; Ethinyl Estradiol; Ethynodiol Diacetate; Female; Flutamide; Hirsutism; Humans; Hyperandrogenism; Insulin Resistance; Remission Induction; Spironolactone; Syndrome | 1997 |
Other antiandrogens.
Topics: Acne Vulgaris; Androgen Antagonists; Cimetidine; Female; Finasteride; Flutamide; Humans; Isotretinoin; Male; Spironolactone | 1998 |
Comment on spironolactone, but not flutamide, administration prevents bone loss in hyperandrogenic women treated with gonadotropin-releasing hormone agonist.
Topics: Female; Flutamide; Gonadotropin-Releasing Hormone; Humans; Hyperandrogenism; Osteoporosis; Spironolactone | 1999 |
Androgen and estrogen stimulation of ornithine decarboxylase activity in mouse kidney.
Topics: Androgen Antagonists; Animals; Cyproterone Acetate; Dichlorodiphenyl Dichloroethylene; Dihydrotestosterone; Estradiol; Female; Flutamide; Kidney; Mice; Mice, Inbred CBA; Ornithine Decarboxylase; Oxazoles; Spironolactone; Testosterone | 2000 |
The treatment of polycystic ovary syndrome.
Topics: Adult; Androgen Antagonists; Cabergoline; Cardiovascular Diseases; Clomiphene; Cyproterone Acetate; Diabetes Complications; Dopamine Agonists; Ergolines; Female; Finasteride; Flutamide; Follicle Stimulating Hormone; Gonadotropins; Hirsutism; Humans; Hypoglycemic Agents; Infertility, Female; Insulin Resistance; Metformin; Mineralocorticoid Receptor Antagonists; Obesity; Ovulation Induction; Polycystic Ovary Syndrome; Risk Factors; Spironolactone; Weight Loss | 2004 |
Treatment of female pattern hair loss with the androgen receptor antagonist flutamide.
Topics: Adult; Alopecia; Androgen Receptor Antagonists; Drug Therapy, Combination; Female; Flutamide; Hair; Humans; Minoxidil; Spironolactone; Treatment Outcome | 2011 |
Hirsutism - from diagnosis to use of antiandrogens.
Topics: Androgen Antagonists; Androstenes; Cyproterone Acetate; Female; Finasteride; Flutamide; Hirsutism; Humans; Hyperandrogenism; Polycystic Ovary Syndrome; Spironolactone | 2013 |