spironolactone has been researched along with diazepam in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (41.18) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (29.41) | 29.6817 |
| 2010's | 5 (29.41) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Abellán Guillén, A; Cordeiro, MN; Garrido Escudero, A; Morales Helguera, A; Pérez-Garrido, A | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Mertin, J; Schmiedek, P; Simon, O | 1 |
| Gillette, JR; Stripp, B | 1 |
| Mécs, I; Savoie, L; Selye, H | 1 |
| Bjondahl, K; Haataja, M; Kangas, L; Möttönen, M; Nieminen, L | 1 |
| Klaassen, CD; Siegers, CP | 1 |
| Nokubo, M; Tsuchiya, M | 1 |
| Armijo, JA; Padrón, FA | 1 |
| López-Rubalcava, C; Oikawa, J; Paez-Martinez, N | 1 |
2 review(s) available for spironolactone and diazepam
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[The importance of the biliary excretion of drugs in the human].
Topics: Anti-Bacterial Agents; Antineoplastic Agents; Bile; Biological Transport; Cardiac Glycosides; Contraceptives, Oral, Hormonal; Diazepam; Digoxin; Enterohepatic Circulation; Fluorenes; Half-Life; Hexamethonium Compounds; Humans; Imipramine; Indocyanine Green; Kidney Diseases; Liver Diseases; Molecular Weight; Pharmaceutical Preparations; Spironolactone | 1983 |
15 other study(ies) available for spironolactone and diazepam
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Convenient QSAR model for predicting the complexation of structurally diverse compounds with beta-cyclodextrins.
Topics: beta-Cyclodextrins; Hydrophobic and Hydrophilic Interactions; Organic Chemicals; Quantitative Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
The influence of aldosterone and anticonvulsant drugs on electroencephalographic and clinical disturbances induced by the spirolactone derivative, potassium canrenoate.
Topics: Aldosterone; Animals; Anticonvulsants; Brain; Diazepam; Disease Models, Animal; Dogs; Electroencephalography; Epilepsy; Female; Male; Phenytoin; Spironolactone | 1975 |
Role of drug metabolism in drug research and development: factors affecting metabolism of drugs and their pharmacological and toxicological activity.
Topics: Animals; Benzene Derivatives; Benzopyrenes; Cortisone; Cytochrome c Group; Cytochrome P-450 Enzyme System; Dealkylation; Diazepam; Female; Guinea Pigs; Hexobarbital; Hydroxylation; Male; Methylcholanthrene; Mice; Microsomes, Liver; Morphine; Oxidoreductases; Pentylenetetrazole; Pharmaceutical Preparations; Phenobarbital; Rats; Research; Sleep; Spironolactone | 1972 |
Inhibition of anesthetics and sedative actions by spironolactone.
Topics: Anesthetics; Animals; Bromides; Chloral Hydrate; Chlorides; Chlorpromazine; Dehydroepiandrosterone; Desoxycorticosterone; Diazepam; Diethylstilbestrol; Ethanol; Female; Hypnotics and Sedatives; Magnesium; Morphine; Pentobarbital; Phenoxybenzamine; Potassium; Pregnanediones; Pregnanes; Progesterone; Rats; Reserpine; Sodium; Spironolactone; Testosterone | 1969 |
Effect of sprionolactone on pentobarbital anaesthesia, diazepam metabolism and toxicity of spironolactone and furosemide.
Topics: Animals; Diazepam; Drug Antagonism; Furosemide; Male; Mice; Oxazepam; Pentobarbital; Rats; Spironolactone; Stimulation, Chemical; Time Factors | 1972 |
The effects of phenobarbital, spironolactone and diazepam on hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in male and female rats.
Topics: Animals; Circadian Rhythm; Diazepam; Female; Hydroxymethylglutaryl CoA Reductases; Liver; Male; Phenobarbital; Rats; Rats, Inbred Strains; Spironolactone | 1983 |
[Correlation of digoxin levels in the myocardium, plasma and saliva in patients under chronic treatment].
Topics: Adult; Aged; Atrial Fibrillation; Diazepam; Digoxin; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Myocardium; Saliva; Spironolactone | 1981 |
Blockade of corticosteroid receptors induces anxiolytic-like effects in streptozotocin-induced diabetic mice, and synergizes with diazepam.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Blood Glucose; Diabetes Mellitus, Experimental; Diazepam; Dose-Response Relationship, Drug; Drug Synergism; Hormone Antagonists; Mice; Mifepristone; Mineralocorticoid Receptor Antagonists; Motor Activity; Receptors, Steroid; Spironolactone; Time Factors | 2013 |