Page last updated: 2024-08-17

spironolactone and dehydroepiandrosterone

spironolactone has been researched along with dehydroepiandrosterone in 35 studies

Research

Studies (35)

Timeframe	Studies, this research(%)	All Research%
pre-1990	17 (48.57)	18.7374
1990's	8 (22.86)	18.2507
2000's	4 (11.43)	29.6817
2010's	6 (17.14)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bellavance, E; Luu-The, V; Poirier, D	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Siiteri, PK; Walsh, PC	1
Liddle, GW; Sennett, JA	1
Liddle, GW	1
Horth, CE; Palmer, RF; Ramsay, LE; Shelton, JR; Tidd, MJ	1
Elkind-Hirsch, KE; Malinak, LR; McConnell, TG; Valdes, CT	1
Crosby, PD; Rittmaster, RS	1
Carmina, E; Lobo, RA	1
Bedocs, NM; Bergfeld, W; Gidwani, GP; Gupta, MK; Parker, R; Redmond, GP; Skibinski, C	1
Tremblay, RR	1
Elkind-Hirsch, K; Goldzieher, JW; Young, RL	1
Lobo, RA; Serafini, P	1
Gibson, M; Krusinski, PA; Kvedar, JC	1
Maxson, WS; Pittaway, DE; Wentz, AC	1
Melby, JC	1
Selye, H; Szabo, S; Taché, Y	1
Mécs, I; Savoie, L; Selye, H	1
Biffignandi, P; Massucchetti, C; Molinatti, GM	1
Braithwaite, SS; Jabamoni, R	1
Lobo, RA; Shoupe, D	1
Coney, P	1
Kirschner, MA; Lerário, AC; Luthold, WW; Marcondes, JA; Mendonça, BB; Minanni, SL; Nery, M; Wajchenberg, BL	1
Demirçay, Z; Durmuşoğlu, F; Erenus, M; Gürbüz, O; Pekin, S	1
Cusan, L; Dupont, A; Gomez, JL; Labrie, F; Tremblay, RR	1
Gökmen, O; Gülekli, B; Işik, AZ; Senöz, S	1
Canosa, LF; Ceballos, NR	1
Chen, W; Thiboutot, D	1
JOHNSEN, SG; LYNGBYE, J	1
Arvat, E; Balbo, M; Baldi, M; Bo, M; Bonelli, L; Ghigo, E; Giordano, R; Migliaretti, G; Pellegrino, M; Picu, A; Vezzari, M	1
Chen, W; Li, GC; Shih, PC; Tzou, DL; Yang, KJ	1
Fiebeler, A; Kirsch, T; Klinge, U; Kolkhof, P; Lindschau, C; Peters, I	1
Dickson, GM	1
Belfiore, A; D'Orrico, B; Fava, A; Fruci, B; Guzzi, P; Malaguarnera, R; Mazza, A; Veltri, P	1
Channar, PA; El-Seedi, H; Faisal, M; Larik, FA; Mehfooz, H; Saeed, A; Shahzad, D	1

Reviews

8 review(s) available for spironolactone and dehydroepiandrosterone

Article	Year
Treatment of hirsutism with spironolactone. Clinics in endocrinology and metabolism, 1986, Volume: 15, Issue:2 Topics: 17-alpha-Hydroxyprogesterone; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Hirsutism; Humans; Hydroxyprogesterones; Kinetics; Menstrual Cycle; Receptors, Androgen; Sex Hormone-Binding Globulin; Spironolactone; Testosterone	1986
Hirsutism: evaluation and treatment. Journal of the American Academy of Dermatology, 1985, Volume: 12, Issue:2 Pt 1 Topics: Contraceptives, Oral; Dehydroepiandrosterone; Dexamethasone; Dihydrotestosterone; Female; Hair Removal; Hirsutism; Humans; Neoplasms; Physical Examination; Sex Hormone-Binding Globulin; Spironolactone; Testosterone	1985
Assessment of adrenocortical function. The New England journal of medicine, 1971, Sep-23, Volume: 285, Issue:13 Topics: 17-Ketosteroids; Addison Disease; Adolescent; Adrenal Glands; Adrenal Insufficiency; Adult; Aldosterone; Androgens; Child; Cushing Syndrome; Dehydroepiandrosterone; Desoxycorticosterone; Dexamethasone; Female; Humans; Hydrocortisone; Hyperaldosteronism; Hypertension; Infant; Male; Pituitary-Adrenal Function Tests; Renin; Spironolactone; Virilism	1971
Female hirsutism: pathophysiological considerations and therapeutic implications. Endocrine reviews, 1984,Fall, Volume: 5, Issue:4 Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Adrenal Glands; Adrenocorticotropic Hormone; Androgen Antagonists; Androgens; Androstenedione; Biological Transport, Active; Blood Proteins; Cyproterone; Cyproterone Acetate; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dexamethasone; Dihydrotestosterone; Female; Hirsutism; Humans; Kinetics; Ovary; Sex Hormone-Binding Globulin; Skin; Spironolactone	1984
Hirsutism. Archives of dermatology, 1983, Volume: 119, Issue:4 Topics: 17-Ketosteroids; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Androgen Antagonists; Androgens; Cimetidine; Dehydroepiandrosterone; Female; Hirsutism; Humans; Ovarian Neoplasms; Spironolactone; Testosterone	1983
Polycystic ovarian disease: current concepts of pathophysiology and therapy. Fertility and sterility, 1984, Volume: 42, Issue:5 Topics: 17-Ketosteroids; Adrenal Cortex; Adrenal Glands; Androgen Antagonists; Androstenedione; Animals; Cimetidine; Cyproterone; Cyproterone Acetate; Dehydroepiandrosterone; Female; Follicle Stimulating Hormone; Humans; Hypothalamo-Hypophyseal System; Luteinizing Hormone; Ovary; Ovulation Induction; Polycystic Ovary Syndrome; Spironolactone; Testosterone	1984
Update and future of hormonal therapy in acne. Dermatology (Basel, Switzerland), 2003, Volume: 206, Issue:1 Topics: Acne Vulgaris; Androgen Antagonists; Androgens; Contraceptives, Oral, Hormonal; Dehydroepiandrosterone; Estradiol Congeners; Ethinyl Estradiol; Glucocorticoids; Humans; Hyperandrogenism; Mineralocorticoid Receptor Antagonists; Sebum; Spironolactone	2003
Synthetic approaches towards the multi target drug spironolactone and its potent analogues/derivatives. Steroids, 2017, Volume: 118 Topics: Aldosterone; Androstadienes; Androstenes; Animals; Canrenone; Chloranil; Dehydroepiandrosterone; Eplerenone; Humans; Molecular Structure; Receptors, Mineralocorticoid; Spironolactone	2017

Trials

7 trial(s) available for spironolactone and dehydroepiandrosterone

Article	Year
Endocrine effects of spironolactone in man. Clinical endocrinology, 1978, Volume: 9, Issue:5 Topics: 17-Ketosteroids; Adolescent; Adult; Androsterone; Clinical Trials as Topic; Dehydroepiandrosterone; Double-Blind Method; Estradiol; Estrogens; Etiocholanolone; Humans; Luteinizing Hormone; Male; Spironolactone; Testosterone	1978
The effects of spironolactone on testosterone fractions and sex-hormone binding globulin binding capacity in hirsute women. Journal of endocrinological investigation, 1995, Volume: 18, Issue:6 Topics: Adolescent; Adult; Body Weight; Dehydroepiandrosterone; Estradiol; Female; Hirsutism; Hormone Antagonists; Humans; Menstruation; Polycystic Ovary Syndrome; Sex Hormone-Binding Globulin; Spironolactone; Testosterone	1995
Comparison of the efficacy of spironolactone versus flutamide in the treatment of hirsutism. Fertility and sterility, 1994, Volume: 61, Issue:4 Topics: Adolescent; Adult; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Flutamide; Follicle Stimulating Hormone; Hirsutism; Humans; Luteinizing Hormone; Spironolactone; Testosterone	1994
Comparison of flutamide and spironolactone in the treatment of hirsutism: a randomized controlled trial. Fertility and sterility, 1994, Volume: 61, Issue:2 Topics: Adult; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Flutamide; Follicle Stimulating Hormone; Hirsutism; Humans; Luteinizing Hormone; Premenopause; Progesterone; Spironolactone; Testosterone	1994
Comparison of four different treatment regimes in hirsutism related to polycystic ovary syndrome. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 1996, Volume: 10, Issue:4 Topics: Adolescent; Adult; Androgen Antagonists; Cholesterol, HDL; Cholesterol, LDL; Cohort Studies; Contraceptives, Oral, Combined; Cyproterone; Dehydroepiandrosterone; Female; Hirsutism; Humans; Ketoconazole; Luteinizing Hormone; Mineralocorticoid Receptor Antagonists; Polycystic Ovary Syndrome; Spironolactone; Testosterone	1996
Hypothalamus-pituitary-adrenal hyperactivity in human aging is partially refractory to stimulation by mineralocorticoid receptor blockade. The Journal of clinical endocrinology and metabolism, 2005, Volume: 90, Issue:10 Topics: Adrenocorticotropic Hormone; Adult; Aged; Aging; Canrenoic Acid; Circadian Rhythm; Dehydroepiandrosterone; Drug Resistance; Female; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Male; Mineralocorticoid Receptor Antagonists; Pituitary-Adrenal System; Spironolactone; Stimulation, Chemical	2005
In PCOS patients the addition of low-dose spironolactone induces a more marked reduction of clinical and biochemical hyperandrogenism than metformin alone. Nutrition, metabolism, and cardiovascular diseases : NMCD, 2014, Volume: 24, Issue:2 Topics: Adult; Androstenedione; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Female; Hirsutism; Humans; Hyperandrogenism; Hypoglycemic Agents; Insulin Resistance; Metformin; Polycystic Ovary Syndrome; Spironolactone; Testosterone; Young Adult	2014

Other Studies

20 other study(ies) available for spironolactone and dehydroepiandrosterone

Article	Year
Potent and selective steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 7, an enzyme that catalyzes the reduction of the key hormones estrone and dihydrotestosterone. Journal of medicinal chemistry, 2009, Dec-10, Volume: 52, Issue:23 Topics: 17-Hydroxysteroid Dehydrogenases; Androstane-3,17-diol; Androstanes; Biocatalysis; Cell Line; Dihydrotestosterone; Enzyme Inhibitors; Estradiol; Estrone; Humans; Inhibitory Concentration 50; Oxidation-Reduction; Substrate Specificity	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Suppression of plasma androgens by spironolactone in castrated men with carcinoma of the prostate. The Journal of urology, 1975, Volume: 114, Issue:2 Topics: Aged; Androgens; Androstenedione; Castration; Dehydroepiandrosterone; Depression, Chemical; Humans; Male; Middle Aged; Neoplasm Metastasis; Prostatic Neoplasms; Spironolactone; Testosterone	1975
New mineralcorticoids in the syndrome of low-renin essential hypertension. Journal of steroid biochemistry, 1975, Volume: 6, Issue:5 Topics: Androstenediols; Biological Assay; Dehydroepiandrosterone; Humans; Hypertension; Mineralocorticoids; Potassium; Renin; Sodium; Spironolactone	1975
The Distinguished Lecture. Is hypertension essential? Transactions of the Association of American Physicians, 1975, Volume: 88 Topics: Aldosterone; Aminoglutethimide; Angiotensin II; Animals; Dehydroepiandrosterone; Humans; Hypertension; Hypertension, Renal; Mineralocorticoids; Natriuresis; Norepinephrine; Patient Compliance; Phenoxybenzamine; Renal Artery Obstruction; Renin; Saralasin; Spironolactone	1975
Androgen responses to acutely increased endogenous insulin levels in hyperandrogenic and normal cycling women. Fertility and sterility, 1991, Volume: 55, Issue:3 Topics: Adrenal Glands; Adult; Androgens; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Follicular Phase; Glucose Tolerance Test; Gonadotropin-Releasing Hormone; Hormones; Humans; Hydrocortisone; Insulin; Leuprolide; Luteal Phase; Ovary; Ovulation; Polycystic Ovary Syndrome; Spironolactone; Testosterone	1991
Predictors of clinical response in hirsute women treated with spironolactone. Fertility and sterility, 1991, Volume: 55, Issue:6 Topics: Adolescent; Adult; Age Factors; Body Mass Index; Child; Contraceptives, Oral; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Hirsutism; Humans; Hysterectomy; Menstrual Cycle; Middle Aged; Oligomenorrhea; Prognosis; Retrospective Studies; Spironolactone; Testosterone; Time Factors	1991
Peripheral androgen blockade versus glandular androgen suppression in the treatment of hirsutism. Obstetrics and gynecology, 1991, Volume: 78, Issue:5 Pt 1 Topics: Adolescent; Adult; Androgen Antagonists; Androgens; Androstane-3,17-diol; Androstenedione; Androsterone; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dexamethasone; Dihydrotestosterone; Drug Combinations; Female; Hirsutism; Humans; Spironolactone; Testosterone	1991
Treatment of androgenic disorders with dexamethasone: dose-response relationship for suppression of dehydroepiandrosterone sulfate. Journal of the American Academy of Dermatology, 1990, Volume: 22, Issue:1 Topics: Acne Vulgaris; Adolescent; Adult; Alopecia; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dexamethasone; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Hirsutism; Humans; Probability; Spironolactone	1990
The endocrine effects of spironolactone used as an antiandrogen. Fertility and sterility, 1987, Volume: 48, Issue:2 Topics: Adult; Androstenedione; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dexamethasone; Female; Hirsutism; Humans; Middle Aged; Ovariectomy; Spironolactone; Testosterone	1987
The effects of spironolactone on adrenal steroidogenesis in hirsute women. Fertility and sterility, 1985, Volume: 44, Issue:5 Topics: 17-alpha-Hydroxyprogesterone; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Androgens; Androstenedione; Cortodoxone; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Hirsutism; Humans; Hydrocortisone; Hydroxyprogesterones; Spironolactone; Steroids; Time Factors	1985
Spironolactone in combination drug therapy for unresponsive hirsutism. Fertility and sterility, 1985, Volume: 43, Issue:6 Topics: Contraceptives, Oral; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dexamethasone; Drug Therapy, Combination; Female; Hirsutism; Humans; Polycystic Ovary Syndrome; Sex Hormone-Binding Globulin; Spironolactone; Testosterone	1985
Interruption of pregnancy by various steroids. Fertility and sterility, 1971, Volume: 22, Issue:11 Topics: Abortion, Induced; Anabolic Agents; Animals; Cholesterol; Dehydroepiandrosterone; Dexamethasone; Digitoxin; Estradiol; Ethylestrenol; Female; Indomethacin; Oxandrolone; Phenobarbital; Prednisolone; Pregnancy; Pregnenolone; Progesterone; Rats; Spironolactone; Steroids; Triamcinolone	1971
Inhibition of anesthetics and sedative actions by spironolactone. Anesthesiology, 1969, Volume: 31, Issue:3 Topics: Anesthetics; Animals; Bromides; Chloral Hydrate; Chlorides; Chlorpromazine; Dehydroepiandrosterone; Desoxycorticosterone; Diazepam; Diethylstilbestrol; Ethanol; Female; Hypnotics and Sedatives; Magnesium; Morphine; Pentobarbital; Phenoxybenzamine; Potassium; Pregnanediones; Pregnanes; Progesterone; Rats; Reserpine; Sodium; Spironolactone; Testosterone	1969
The influence of androgens on insulin resistance. Fertility and sterility, 1984, Volume: 41, Issue:3 Topics: Adult; Androgens; Androstane-3,17-diol; Dehydroepiandrosterone; Dihydrotestosterone; Female; Hirsutism; Humans; Insulin; Insulin Resistance; Luteinizing Hormone; Pituitary Hormone-Releasing Hormones; Polycystic Ovary Syndrome; Spironolactone; Testosterone	1984
Effects of different steroid-biosynthesis inhibitors on the testicular steroidogenesis of the toad Bufo arenarum. Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2001, Volume: 171, Issue:6 Topics: 17-Hydroxysteroid Dehydrogenases; Androgen Antagonists; Androgens; Animals; Bufonidae; Cholestenone 5 alpha-Reductase; Cyanoketone; Dehydroepiandrosterone; Enzyme Inhibitors; Finasteride; Male; Oxidoreductases; Pregnenolone; Spironolactone; Steroid 17-alpha-Hydroxylase; Testis; Testosterone	2001
ADMINISTRATION OF SPIRONOLACTONE AS A SOURCE OF ERROR IN DETERMINATION OF 17-KETOSTEROIDS IN URINE. Scandinavian journal of clinical and laboratory investigation, 1964, Volume: 16 Topics: 17-Ketosteroids; Adolescent; Dehydroepiandrosterone; Humans; Pharmacology; Spironolactone; Urine	1964
Conformational analysis of steroid hormone molecules in the lipid environment--a solid-state NMR approach. Steroids, 2011, Volume: 76, Issue:6 Topics: Carbon Isotopes; Dehydroepiandrosterone; Lipids; Magnetic Resonance Spectroscopy; Molecular Conformation; Spironolactone	2011
Dehydroepiandrosterone-induced phosphorylation and translocation of FoxO1 depend on the mineralocorticoid receptor. Hypertension (Dallas, Tex. : 1979), 2011, Volume: 58, Issue:3 Topics: Animals; Blotting, Western; Cells, Cultured; CHO Cells; Cricetinae; Cricetulus; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Endothelial Cells; Eplerenone; Fibroblasts; Forkhead Box Protein O1; Forkhead Transcription Factors; Humans; Microscopy, Confocal; Mineralocorticoid Receptor Antagonists; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Protein Transport; Rats; Receptors, Mineralocorticoid; RNA Interference; Spironolactone; Time Factors	2011
Menopause management: how you can do better. The Journal of family practice, 2012, Volume: 61, Issue:3 Topics: Acupuncture Therapy; Adjuvants, Immunologic; Administration, Cutaneous; Administration, Topical; Affect; Age Factors; Androgen Antagonists; Androgens; Antidepressive Agents; Antidepressive Agents, Second-Generation; Atrophic Vaginitis; Azabicyclo Compounds; Bupropion; Cyproterone Acetate; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Dyspareunia; Estrogens; Eszopiclone; Exercise; Female; Hair; Hormone Replacement Therapy; Hot Flashes; Humans; Hypnotics and Sedatives; Libido; Life Style; Lubricants; Menopause; Middle Aged; Mineralocorticoid Receptor Antagonists; Minoxidil; Phytotherapy; Piperazines; Sleep Initiation and Maintenance Disorders; Spironolactone; Testosterone	2012