Page last updated: 2024-08-17

spironolactone and cycloheximide

spironolactone has been researched along with cycloheximide in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199015 (45.45)18.7374
1990's4 (12.12)18.2507
2000's13 (39.39)29.6817
2010's1 (3.03)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Handler, JS; Keiser, HR; Zusman, RM1
Kishikawa, T; Kugai, N; Nishiki, K; Ogata, E1
Hayashi, T; Miyabo, S; Nakai, T1
Brun, HP; Caillaud, JM; Cordier, A; Leonard, JF; Melcion, C; Moronvalle, V1
Jazayeri, A; Meyer, WJ1
Gangnerau, MN; Picon, R; Rouiller, V1
Fregly, MJ; Sumners, C1
Japundzić, I; Japundzić, M; Szabo, S1
Japundzić, I; Japurdzić, M; Mimić-Oka, J; Szabó, S1
Greengard, P; Liu, AY1
Selye, H1
Dardachti, D; Garg, BD; Khandekar, JD; Kovacs, K; Tuchweber, B1
Krajny, M; Solymoss, B; Toth, S; Varga, S2
Porter, GA1
Krajny, M; Solymoss, B; Varga, S; Werringloer, J1
Edelman, IS; Garty, H; Lindemann, B1
Christ, M; Falkenstein, E; Günther, A; Heck, M; Schmidt, BM; Wehling, M1
Amemiya, M; Asano, Y; Ebata, S; Muto, S; Nemoto, J; Okada, K; Saito, T1
Asano, Y; Ebata, S; Muto, S; Okada, K; Saito, T1
Harvey, BJ; Urbach, V1
Bousquet, J; Harvey, BJ; Mainprice, B; Urbach, V; Walsh, DE1
Alzamora, R; Gonzalez, M; Marusic, ET; Michea, L1
Abe, T; Arima, S; Ito, S; Kohagura, K; Satoh, F; Sugawara, A; Takeuchi, K; Xu, HL1
Geibel, JP; Giebisch, G; Schulz, N; Wagner, CA; Winter, C1
Brunette, MG; Couchourel, D; Leclerc, M1
Chen, Y; Qi, A; Xiao, L1
Fujita, Y; Ishizawa, K; Ito, H; Izawa, Y; Kanematsu, Y; Miki, C; Miyata, K; Nishiyama, A; Tamaki, T; Tsuchiya, K; Yoshizumi, M1
Hirata, Y; Hirono, Y; Iwashima, F; Minami, I; Sakai, H; Sakurada, M; Sato, R; Sugiyama, T; Suzuki, N; Tateno, T; Tsuchiya, K; Yoshimoto, T1
Leite-Dellova, DC; Malnic, G; Mello-Aires, M; Oliveira-Souza, M1
de Mello-Aires, M; Leite-Dellova, D; Pergher, PS1
Carretero, OA; D'Ambrosio, MA; Garvin, JL; Kutskill, K; Leung, P; Peterson, EL; Ren, Y; Wang, H1

Other Studies

33 other study(ies) available for spironolactone and cycloheximide

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Effect of adrenal steroids on vasopressin-stimulated PGE synthesis and water flow.
    The American journal of physiology, 1978, Volume: 234, Issue:6

    Topics: Adrenal Cortex Hormones; Aldosterone; Animals; Arachidonic Acids; Arginine Vasopressin; Body Water; Bufo marinus; Cycloheximide; Dactinomycin; Dexamethasone; In Vitro Techniques; Progesterone; Prostaglandins E; Sodium; Spironolactone; Triamcinolone; Urinary Bladder; Vasopressins

1978
Oxidative response to aldosterone of pyridine nucleotide in rat kidney in situ.
    The American journal of physiology, 1977, Volume: 232, Issue:4

    Topics: Adenine Nucleotides; Aldosterone; Animals; Calcitonin; Cycloheximide; Dactinomycin; Desoxycorticosterone; Dexamethasone; Dinitrophenols; Dose-Response Relationship, Drug; Energy Metabolism; Glycyrrhetinic Acid; Hemorrhage; Kidney; Male; Malonates; NAD; Ouabain; Oxidation-Reduction; Pyruvates; Rats; Rotenone; Spironolactone; Water

1977
Glucocorticoids increase Ca2+ uptake and [3H]dihydropyridine binding in A7r5 vascular smooth muscle cells.
    The American journal of physiology, 1991, Volume: 261, Issue:1 Pt 1

    Topics: Amiloride; Analysis of Variance; Androstanols; Animals; Calcium; Calcium Channels; Cell Count; Cell Line; Cycloheximide; Dactinomycin; Dexamethasone; Dihydropyridines; Electric Conductivity; Glucocorticoids; Indomethacin; Kinetics; Muscle, Smooth, Vascular; Potassium; Proteins; Rats; Receptors, Glucocorticoid; Spironolactone; Water

1991
Pig Leydig cell culture: a useful in vitro test for evaluating the testicular toxicity of compounds.
    Toxicology and applied pharmacology, 1991, Volume: 108, Issue:2

    Topics: Aminoglutethimide; Animals; Cell Survival; Cells, Cultured; Chlorpromazine; Chorionic Gonadotropin; Cyclic AMP; Cycloheximide; Ketoconazole; Kinetics; Leydig Cells; Male; Progesterone; Spironolactone; Steroids; Swine; Testis; Testosterone; Time Factors; Toxicology

1991
Mineralocorticoid-induced increase in beta-adrenergic receptors of cultured rat arterial smooth muscle cells.
    Journal of steroid biochemistry, 1989, Volume: 33, Issue:5

    Topics: Aldosterone; Animals; Cells, Cultured; Cyclic AMP; Cycloheximide; Dihydroalprenolol; Mifepristone; Muscle, Smooth, Vascular; Rats; Receptors, Adrenergic, beta; Spironolactone

1989
Production of C21 steroids in rat fetal ovaries.
    Journal of steroid biochemistry, 1988, Volume: 31, Issue:4A

    Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Bucladesine; Cycloheximide; Female; Hydroxycholesterols; Kinetics; Organ Culture Techniques; Ovary; Pregnenolone; Progesterone; Rats; Rats, Inbred Strains; Spironolactone; Steroid 17-alpha-Hydroxylase

1988
Modulation of angiotensin II binding sites in neuronal cultures by mineralocorticoids.
    The American journal of physiology, 1989, Volume: 256, Issue:1 Pt 1

    Topics: Aldosterone; Angiotensin II; Animals; Astrocytes; Brain Stem; Cells, Cultured; Corticosterone; Cycloheximide; Desoxycorticosterone; Dexamethasone; Dose-Response Relationship, Drug; Estradiol; Hypothalamus; Mineralocorticoids; Neurons; Progesterone; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Spironolactone; Testosterone

1989
Induction of ethylmorphine demethylation and aniline p-hydroxylation by various catatoxic steroids in regenerating rat liver.
    European journal of biochemistry, 1974, Mar-15, Volume: 43, Issue:1

    Topics: Androstenols; Aniline Compounds; Animals; Cycloheximide; Dactinomycin; Enzyme Induction; Female; Hepatectomy; Ketosteroids; Liver; Liver Regeneration; Mixed Function Oxygenases; Morphinans; Oxidoreductases, N-Demethylating; Pregnenolone Carbonitrile; Propionates; Rats; Spectrophotometry; Spironolactone; Steroids; Steroids, Fluorinated; Time Factors

1974
Influence of spironolactone and dexamethasone on phosphoprotein phosphatase in the rat liver, kidney and spleen.
    European journal of biochemistry, 1972, Aug-04, Volume: 28, Issue:4

    Topics: Animals; Caseins; Cycloheximide; Dactinomycin; Dexamethasone; Enzyme Induction; Female; Kidney; Liver; Microsomes; Phosphoproteins; Phosphoric Monoester Hydrolases; Proadifen; Rats; Spironolactone; Spleen

1972
Aldosterone-induced increase in protein phosphatase activity of toad bladder.
    Proceedings of the National Academy of Sciences of the United States of America, 1974, Volume: 71, Issue:10

    Topics: Adenosine Triphosphate; Aldosterone; Animals; Autoradiography; Bufo marinus; Cyclic AMP; Cycloheximide; Dactinomycin; Enzyme Activation; In Vitro Techniques; Microsomes; Mineralocorticoid Receptor Antagonists; Phosphoric Monoester Hydrolases; Phosphorus Radioisotopes; Proteins; Puromycin; Spironolactone; Urinary Bladder

1974
Protection by catatoxic steroids against cycloheximide intoxication.
    Toxicology and applied pharmacology, 1970, Volume: 17, Issue:3

    Topics: Anabolic Agents; Animals; Cycloheximide; Desoxycorticosterone; Estradiol; Ethylestrenol; Female; Norsteroids; Oxandrolone; Poisoning; Prednisolone; Pregnanediol; Pregnanediones; Progesterone; Rats; Spironolactone; Steroids; Thyroxine; Triamcinolone

1970
Effect of cycloheximide on the ultrastructural changes produced by spironolactone and pregnenolone-16 alpha-carbonitrile in the rat liver.
    Beitrage zur Pathologie, 1971, Volume: 144, Issue:1

    Topics: Animals; Cycloheximide; Endoplasmic Reticulum; Female; Liver; Microscopy, Electron; Microsomes, Liver; NADP; Nitriles; Pregnenolone; Rats; Spironolactone

1971
Influence of spironolactone and other steroids on the plasma level of digitoxin.
    Recent advances in studies on cardiac structure and metabolism, 1972, Volume: 1

    Topics: Animals; Cycloheximide; Digitoxin; Ethylestrenol; Female; Norpregnenes; Proadifen; Rats; Spironolactone; Time Factors

1972
The action of aldosterone on transepithelial sodium transport in isolated ventral toad skin.
    General and comparative endocrinology, 1971, Volume: 16, Issue:3

    Topics: Aldosterone; Animals; Anura; Biological Transport, Active; Cycloheximide; Dactinomycin; Depression, Chemical; Electrophysiology; Glucose; Hexoses; In Vitro Techniques; Ouabain; Skin Physiological Phenomena; Sodium; Spironolactone; Stimulation, Chemical

1971
Suppression by nucleic acid- and protein-synthesis inhibitors of drug detoxication induced by spironolactone or ethylestrenol.
    The Journal of pharmacology and experimental therapeutics, 1970, Volume: 174, Issue:3

    Topics: Anesthesia; Animals; Antimetabolites; Chloramphenicol; Cycloheximide; Dactinomycin; Ethylestrenol; Female; Mercaptopurine; Pentobarbital; Protein Biosynthesis; Puromycin; Rats; RNA; Spironolactone

1970
The influence of spironolactone on its own biotransformation.
    Steroids, 1970, Volume: 16, Issue:3

    Topics: Animals; Biotransformation; Cycloheximide; Depression, Chemical; Female; Methods; Microsomes, Liver; Proadifen; Rats; Spironolactone

1970
Metabolic regulation of apical sodium permeability in toad urinary bladder in the presence and absence of aldosterone.
    The Journal of membrane biology, 1983, Volume: 74, Issue:1

    Topics: Aldosterone; Animals; Biological Transport; Bufo marinus; Calcium; Cell Membrane Permeability; Cycloheximide; Deoxyglucose; Energy Metabolism; Ion Channels; Male; Oxythiamine; Pyruvates; Pyruvic Acid; Sodium; Spironolactone; Urinary Bladder

1983
Aldosterone, not estradiol, is the physiological agonist for rapid increases in cAMP in vascular smooth muscle cells.
    Circulation, 1999, Mar-23, Volume: 99, Issue:11

    Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Aldosterone; Animals; Calcium Signaling; Coronary Vessels; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cycloheximide; Estradiol; Gene Expression Regulation; Hydrocortisone; Isoproterenol; Mineralocorticoid Receptor Antagonists; Muscle, Smooth, Vascular; Phosphorylation; Protein Processing, Post-Translational; Protein Synthesis Inhibitors; Spironolactone; Swine; Sympathomimetics; Transcription, Genetic

1999
Aldosterone activates Na+/H+ exchange in vascular smooth muscle cells by nongenomic and genomic mechanisms.
    Kidney international, 1999, Volume: 56, Issue:4

    Topics: Aldosterone; Animals; Aorta, Thoracic; Cells, Cultured; Cycloheximide; Cytoskeleton; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Activation; Gene Expression; Hormone Antagonists; Hydrogen-Ion Concentration; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Muscle, Smooth, Vascular; Protein Kinase C; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Sodium-Hydrogen Exchangers; Spironolactone; Transcription, Genetic

1999
Glucocorticoid modulates Na+/H+ exchange activity in vascular smooth muscle cells by nongenomic and genomic mechanisms.
    Kidney international, 2000, Volume: 57, Issue:6

    Topics: Animals; Cells, Cultured; Corticosterone; Cycloheximide; Cytoskeleton; Dactinomycin; Dose-Response Relationship, Drug; Genome; Hydrogen-Ion Concentration; Intracellular Membranes; Male; Mifepristone; Muscle, Smooth, Vascular; Nucleic Acid Synthesis Inhibitors; Protein Kinase C; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Steroid; RNA, Messenger; Sodium-Hydrogen Exchangers; Spironolactone

2000
Rapid and non-genomic reduction of intracellular [Ca(2+)] induced by aldosterone in human bronchial epithelium.
    The Journal of physiology, 2001, Nov-15, Volume: 537, Issue:Pt 1

    Topics: Adenylyl Cyclases; Aldosterone; Bronchi; Calcium; Cell Line, Transformed; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Enzyme Inhibitors; Epithelial Cells; Glucocorticoids; GTP-Binding Proteins; Humans; Intracellular Membranes; Mineralocorticoid Receptor Antagonists; Osmolar Concentration; Protein Synthesis Inhibitors; Sodium; Spironolactone; Thapsigargin; Time Factors; Uridine Triphosphate; Vanadates

2001
Rapid non-genomic inhibition of ATP-induced Cl- secretion by dexamethasone in human bronchial epithelium.
    The Journal of physiology, 2002, 12-15, Volume: 545, Issue:3

    Topics: Adenosine Triphosphate; Bronchi; Calcium; Cell Line; Chlorides; Cycloheximide; Dexamethasone; Epithelium; Glucocorticoids; Hormone Antagonists; Humans; Intracellular Membranes; Mifepristone; Mineralocorticoid Receptor Antagonists; Osmolar Concentration; Protein Synthesis Inhibitors; Signal Transduction; Spironolactone; Time Factors

2002
Nongenomic effect of aldosterone on Na+,K+-adenosine triphosphatase in arterial vessels.
    Endocrinology, 2003, Volume: 144, Issue:4

    Topics: Aldosterone; Animals; Aorta, Thoracic; Catalytic Domain; Cycloheximide; Dactinomycin; Enzyme Inhibitors; Eplerenone; Indoles; Ionophores; Male; Maleimides; Mineralocorticoid Receptor Antagonists; Monensin; Protein Biosynthesis; Protein Kinase C; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Sodium; Sodium-Potassium-Exchanging ATPase; Spironolactone; Transcription, Genetic

2003
Nongenomic vascular action of aldosterone in the glomerular microcirculation.
    Journal of the American Society of Nephrology : JASN, 2003, Volume: 14, Issue:9

    Topics: Aldosterone; Animals; Arterioles; Calcium Channel Blockers; Capillaries; Cycloheximide; Dactinomycin; Endothelium, Vascular; In Vitro Techniques; Kidney Glomerulus; Male; Mineralocorticoid Receptor Antagonists; Neomycin; Protein Synthesis Inhibitors; Rabbits; Spironolactone; Vascular Resistance; Vasoconstriction

2003
Nongenomic stimulation of vacuolar H+-ATPases in intercalated renal tubule cells by aldosterone.
    Proceedings of the National Academy of Sciences of the United States of America, 2004, Feb-24, Volume: 101, Issue:8

    Topics: Aldosterone; Animals; Bicarbonates; Colchicine; Cycloheximide; Hydrogen-Ion Concentration; Immunohistochemistry; Kidney Tubules; Kinetics; Mice; Mice, Inbred C57BL; Spironolactone; Vacuolar Proton-Translocating ATPases

2004
Aldosterone enhances renal calcium reabsorption by two types of channels.
    Kidney international, 2004, Volume: 66, Issue:1

    Topics: Absorption; Aldosterone; Animals; Biological Transport; Calcium; Calcium Channels, L-Type; Calcium Channels, T-Type; Canrenone; Cycloheximide; Kidney; Kidney Tubules, Distal; Kidney Tubules, Proximal; Kinetics; Membranes; Mineralocorticoid Receptor Antagonists; Protein Synthesis Inhibitors; Rabbits; Second Messenger Systems; Sodium; Spironolactone; Time Factors

2004
Cultured embryonic hippocampal neurons deficient in glucocorticoid (GC) receptor: a novel model for studying nongenomic effects of GC in the neural system.
    Endocrinology, 2005, Volume: 146, Issue:9

    Topics: Animals; Cell Culture Techniques; Cell Survival; Corticosterone; Culture Media, Serum-Free; Cycloheximide; Hippocampus; Hormone Antagonists; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mifepristone; Mineralocorticoid Receptor Antagonists; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neurons; p38 Mitogen-Activated Protein Kinases; PC12 Cells; Phosphorylation; Protein Synthesis Inhibitors; Rats; Receptors, Glucocorticoid; RNA, Messenger; Serum Albumin, Bovine; Spironolactone

2005
Aldosterone stimulates vascular smooth muscle cell proliferation via big mitogen-activated protein kinase 1 activation.
    Hypertension (Dallas, Tex. : 1979), 2005, Volume: 46, Issue:4

    Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Aldosterone; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Proliferation; Cells, Cultured; Cycloheximide; Enzyme Activation; Eplerenone; Flavonoids; Genes, Dominant; MAP Kinase Kinase 5; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase 7; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Protein Synthesis Inhibitors; Rats; Receptors, Mineralocorticoid; Spironolactone; Transfection

2005
Aldosterone increases osteopontin gene expression in rat endothelial cells.
    Biochemical and biophysical research communications, 2005, Oct-14, Volume: 336, Issue:1

    Topics: Aldosterone; Animals; Base Sequence; Cells, Cultured; Cycloheximide; DNA Primers; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Mifepristone; Mineralocorticoid Receptor Antagonists; Osteopontin; Protein Synthesis Inhibitors; Rats; Receptors, Glucocorticoid; RNA, Messenger; Sialoglycoproteins; Spironolactone

2005
Genomic and nongenomic dose-dependent biphasic effect of aldosterone on Na+/H+ exchanger in proximal S3 segment: role of cytosolic calcium.
    American journal of physiology. Renal physiology, 2008, Volume: 295, Issue:5

    Topics: Aldosterone; Ammonium Chloride; Animals; Calcium; Calcium Signaling; Cycloheximide; Cytosol; Dactinomycin; Gene Expression; Guanidines; Hydrogen-Ion Concentration; In Vitro Techniques; Kidney Tubules, Proximal; Male; Methacrylates; Mifepristone; Rats; Rats, Wistar; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Reverse Transcriptase Polymerase Chain Reaction; Sodium; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; Spironolactone; Sulfones

2008
Direct action of aldosterone on bicarbonate reabsorption in in vivo cortical proximal tubule.
    American journal of physiology. Renal physiology, 2009, Volume: 296, Issue:5

    Topics: Aldosterone; Animals; Bicarbonates; Cycloheximide; Dactinomycin; Hydrogen-Ion Concentration; Kidney Cortex; Kidney Tubules, Proximal; Male; Microelectrodes; Mineralocorticoid Receptor Antagonists; Nucleic Acid Synthesis Inhibitors; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Spironolactone

2009
Aldosterone sensitizes connecting tubule glomerular feedback via the aldosterone receptor GPR30.
    American journal of physiology. Renal physiology, 2014, Aug-15, Volume: 307, Issue:4

    Topics: Aldosterone; Amiloride; Animals; Arterioles; Cycloheximide; Dactinomycin; Epithelial Sodium Channels; Eplerenone; Feedback; Kidney Tubules; Male; Rabbits; Receptors, G-Protein-Coupled; Receptors, Mineralocorticoid; Spironolactone

2014