spironolactone has been researched along with corticosterone in 181 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 55 (30.39) | 18.7374 |
| 1990's | 43 (23.76) | 18.2507 |
| 2000's | 42 (23.20) | 29.6817 |
| 2010's | 37 (20.44) | 24.3611 |
| 2020's | 4 (2.21) | 2.80 |
| Authors | Studies |
|---|---|
| Haga, N; Ishibashi, M; Itoh, T; Kamata, S; Matsui, T; Nakamura, M; Odaguchi, K; Shimizu, T; Suzuki, T; Yamada, F | 1 |
| Bao, Y; Kanai, N; Lu, R; Schuster, VL; Wolkoff, AW | 1 |
| Ernst, B; Lill, MA; Vedani, A; Winiger, F | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Abellán Guillén, A; Cordeiro, MN; Garrido Escudero, A; Morales Helguera, A; Pérez-Garrido, A | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Bellavance, E; Luu-The, V; Poirier, D | 1 |
| Álvarez de la Rosa, D; Gerona-Navarro, G; González-Muñiz, R; Martín-Martínez, M; Pérez-Gordillo, FL; Rodríguez, Y; Zhou, MM | 1 |
| Karlmar, KE | 1 |
| Aupetit, B; Bastien, C; Legrand, JC | 1 |
| Anderson, NS; Fanestil, DD | 1 |
| Aguilera, G; Catt, KJ | 1 |
| Varma, MM | 1 |
| Biglieri, EG; Schambelan, M | 1 |
| Wexler, BC | 1 |
| Agarwal, MK; Coupry, F; Philippe, M | 1 |
| Bader, M; Djavidani, B; Ganten, D; Maser-Gluth, C; Mullins, J; Peters, J; Sander, M; Vecsei, P | 1 |
| Gomez-Sanchez, CE; Gomez-Sanchez, EP | 1 |
| Levin, RJ; Nzegwu, HC | 1 |
| Morris, DJ; Souness, GW | 2 |
| Lewicka, S; Vecsei, P; Weindel, K | 1 |
| Aragonés, A; Gonzalez, CB; Lantos, CP; Spinedi, NC | 1 |
| Carlier, E; Rey, M; Soumireu-Mourat, B; Talmi, M | 1 |
| De Nicola, AF; Grillo, C; McEwen, BS; Vallee, S | 1 |
| Ichikawa, S; Murata, K; Nakamura, T; Ono, Z; Sakamaki, T; Sakamoto, H; Takayama, Y | 1 |
| de Jong, W; de Kloet, ER; van den Berg, DT; van Dijken, HH | 1 |
| Takada, M | 1 |
| Alliet, P; Lebenthal, E; Lee, PC; Lu, RB; Madrazo de la Garza, JA; Santer, R | 1 |
| Davda, MM; Luttge, WG; Rupp, ME | 1 |
| Bloemers, M; de Kloet, ER; Ratka, A; Sutanto, W | 1 |
| Fregly, MJ; Sumners, C | 1 |
| Alexander, EA; Bengele, HH; Perrone, RD | 1 |
| Duncan, RL; Grogan, WM; Kramer, LB; Watlington, CO | 1 |
| de Kloet, ER; Sutanto, W | 1 |
| Capek, K; Pácha, J; Popp, M | 1 |
| De Kloet, ER; De Kock, S; Schild, V; Veldhuis, HD | 1 |
| Aupetit, B; Blanchouin-Emeric, N; Defaye, G; Toury, R; Vonarx, V | 1 |
| Bentley, PJ; Grubb, BR | 1 |
| De Nicola, AF; Lambdin, LT; McEwen, BS; Rainbow, TC | 1 |
| Beaumont, K | 1 |
| Bradshaw, SD; Nagy, KA; Shoemaker, VH | 1 |
| Kourounakis, P; Selye, H; Szabo, S | 1 |
| Richards, P | 1 |
| Erbler, HC | 1 |
| Spark, RF | 1 |
| Bartter, FC; Golde, DW; Roth, JA; Simopoulos, AP | 1 |
| Beevers, DG; Brown, JJ; Davies, DL; Ferriss, JB; Fraser, R; Kremer, D; Lever, AF; Robertson, JI | 1 |
| Selye, H | 1 |
| Ilett, KF; Lockett, MF | 1 |
| Fukuchi, S; Nakajima, K; Nishisato, K; Takenouchi, T | 1 |
| Durszt, F; László, F; Petri, G | 1 |
| Mills, IH | 1 |
| Ogawa, E; Shibata, K; Suzuki, S | 1 |
| Garcia, HA; Hofmann, LM; Krupnick, MI | 1 |
| Vogel, HG | 1 |
| Bartter, FC; Bell, NH; George, JM; Wright, L | 1 |
| Handler, JS; Orloff, J; Preston, AS | 1 |
| Delarue, NC; Laidlaw, JC; Ruse, JL; Salti, IS; Stiefel, M | 1 |
| Elizondo, RS; LeBrie, SJ | 1 |
| Lalone, RC; Levinsky, NG; Lindheimer, MD | 1 |
| Chabert, PR; Guelpa-Decorzant, C; Riondel, AM; Vallotton, MB | 1 |
| Hendry, IA; Hill, CE; McLennan, IS | 1 |
| Chabert, P; Gaillard, RC; Riondel, AM; Vallotton, MB | 1 |
| Gaillard, R; Guelpa-Decorzant, C; Riondel, AM; Vallotton, MB | 1 |
| Sekihara, H | 1 |
| Alvis, R; Cox, M; Geheb, M; Hercker, E; Owen, A | 1 |
| Latif, S; McDermott, M; Morris, DJ | 1 |
| Abshagen, U; Spörl, S | 1 |
| Isola, G; Mandich, A; Uva, B; Vallarino, M | 1 |
| Brewer, KJ; Ensor, DM | 1 |
| Magariños, AM; McEwen, BS; Pavlides, C; Watanabe, Y | 1 |
| Li, P; Xue, LM; Zhu, DN | 1 |
| Engel, JA; Eriksson, CJ; Fahlke, C; Hansen, S; Hård, E | 1 |
| de Jong, W; de Kloet, ER; Van den Berg, DT | 1 |
| Keith, LD; Roberts, AJ | 1 |
| Kageyama, Y; Saruta, T; Suzuki, H | 1 |
| de Kloet, ER; Fluttert, M; Oitzl, MS | 1 |
| Edwards, CR; Sang, KS; Walker, BR; Williams, BC | 1 |
| Brooke, S; Jacobson, L; Sapolsky, R | 1 |
| de Kloet, ER; Meijer, OC | 1 |
| Borkowski, J; Gentsch, C; Mondadori, C | 1 |
| Fahlke, C; Hansen, S; Hård, E | 1 |
| Crabbé, J; Lyoussi, B | 1 |
| Feldman, S; Itzik, A; Weidenfeld, J | 1 |
| Funder, JW; Liu, JP; Sato, A | 1 |
| Knepper, MA; Nolan, PJ; Packer, RK | 1 |
| de Kloet, ER; Oitzl, MS; van Haarst, AD | 1 |
| Cordero, MI; Sandi, C | 1 |
| Costall, B; Murphy, D; Smythe, JW | 1 |
| Barker, KS; Davis, AT; Rollins-Smith, LA | 1 |
| Cole, MA; Kalman, BA; Kim, PJ; Spencer, RL | 2 |
| Johnson, JP; Latif, SA; Morris, DJ; Rokaw, MD; Watlington, CO | 1 |
| Bohus, B; Buwalda, B; Douma, BR; Korte, SM; la Fleur, SE; Luiten, PG | 1 |
| Khoo, K; Krozowski, ZS; Li, KX; Sheppard, KE | 1 |
| Asano, Y; Ebata, S; Kawakami, K; Muto, S; Nemoto, J | 1 |
| Bitran, D; Dowd, JA; Dugan, MM; Renda, P; Shiekh, M | 1 |
| Herman, JP; Spencer, R | 1 |
| Daisley, JN; Loscertales, M; Rose, SP; Sandi, C | 1 |
| Buwalda, B; Douma, BR; Jansen, K; Korte, SM; Luiten, PG; Van der Zee, EA | 1 |
| Fluharty, SJ; Ma, LY; McEwen, BS; Sakai, RR | 1 |
| Frömter, E; Rabe, A | 1 |
| de Kloet, RE; Haller, J; Kruk, MR; Millar, S; van de Schraaf, J | 1 |
| Liu, YJ; Nakagawa, Y; Nakanishi, T; Ohzeki, T; Saegusa, H; Toya, K; Wang, Y | 1 |
| Asano, Y; Ebata, S; Muto, S; Okada, K; Saito, T | 1 |
| Cole, MA; Kalman, BA; Lowrey, MJ; Pace, TW; Spencer, RL; Topczewski, F | 1 |
| Demura, M; Mabuchi, H; Miyamori, I; Takeda, Y; Yoneda, T | 1 |
| Deak, T; Fleshner, M; Maier, SF; Nguyen, KT; Watkins, LR | 1 |
| Herman, JP; McCullers, DL | 1 |
| Calvo, N; Volosin, M | 1 |
| Bilang-Bleuel, A; Droste, SK; Gesing, A; Holsboer, F; Linthorst, AC; Reul, JM | 1 |
| Imaki, T; Naruse, M; Sato, A; Takagi, S; Takano, K; Tanabe, A; Tsuchiya, K | 1 |
| Herman, JP; McCullers, DL; Scheff, SW; Sullivan, PG | 1 |
| Delyani, J; Martin-Berger, CL; McMahon, E; Rocha, R; Scherrer, R; Yang, P | 1 |
| DEBRIS, P; DELAITRE, R; GABILAN, JC; GERBEAUX, S; HABIB, R; MATHIEU, H; PASQUALINI, JR; RAYNAUD, C; ROYER, P | 1 |
| LEAF, A; SHARP, GW | 1 |
| CRABBE, J | 1 |
| de Kloet, ER; Holsboer, F; Levine, S; Müller, MB; Oitzl, MS; Schmidt, M; Schmidt, MV; van der Mark, M | 1 |
| Beck, KD; Moldow, RL; Servatius, RJ; Weaver, S | 1 |
| Pace, TW; Spencer, RL | 1 |
| Harris, BR; Little, HJ; Littleton, JM; Mulholland, PJ; Prendergast, MA; Self, RL | 1 |
| Barrère-Lemaire, S; Bénitah, JP; Lalevée, N; Nargeot, J; Perrier, E; Rebsamen, MC; Rossier, MF | 1 |
| Chen, Y; Qi, A; Xiao, L | 1 |
| Herbert, J; Wong, EY | 1 |
| Dong, Q; Ge, RS; Hardy, MP; Latif, SA; Morris, DJ; Sottas, CM | 1 |
| Ichihara, S; Izawa, H; Kato, T; Kimata, H; Murohara, T; Nagata, K; Noda, A; Obata, K; Xu, J; Yokota, M | 1 |
| Funder, JW | 2 |
| Shibata, H | 1 |
| Khaksari, M; Rashidy-Pour, A; Vafaei, AA | 1 |
| Koizumi, M; Yada, T | 1 |
| Rudakova, E; Volk, T; Wagner, M | 1 |
| Budziszewska, B; Chocyk, A; Grzegorzewska, M; Hess, G; Maćkowiak, M; Wedzony, K | 1 |
| Chang, YT; Chen, HI; Chen, YC; Jen, CJ; Kuo, YM; Wu, CW; Yu, L | 1 |
| Hlavacova, N; Jezova, D | 1 |
| Bagamasbad, P; Bonett, RM; Denver, RJ; Hu, F | 1 |
| Huang, BS; Jeng, AY; Leenen, FH; White, RA | 1 |
| Aznar, S; Brandwein, C; Chourbaji, S; Gass, P; Halldin, C; Kirkegaard, L; Knudsen, GM; Krey, G; Marcussen, AB; Ridder, S; Thomsen, MS; Trajkovska, V | 1 |
| de Kloet, ER; Oitzl, MS; Schächinger, H; Schwabe, L | 1 |
| Bakos, J; Hlavacova, N; Jezova, D | 1 |
| Fan, Y; Sun, Z; Zha, Q; Zhu, MY | 1 |
| Chen, CC; Hsu, KS; Huang, CC; Yang, CH | 1 |
| Cao, J; Duan, TT; Mao, RR; Tan, JW; Tian, M; Xu, L; Zhou, QX | 1 |
| Noble, J; Seckl, JR; Yau, JL | 1 |
| de Gortari, P; López-Rubalcava, C; Mostalac-Preciado, CR | 1 |
| Danielewicz, J; Hess, G; Spyrka, J | 1 |
| Briones, AM; Callera, GE; He, Y; Montezano, AC; Nguyen Dinh Cat, A; Touyz, RM; Yogi, A | 1 |
| Gan, WB; Liston, C | 1 |
| Jadavji, NM; Metz, GA; Supina, RD | 1 |
| Acosta, GB; Kuramoto, N; Nakamura, Y; Ogita, K; Shiba, T; Shuto, M; Sugiyama, C; Yamaguchi, T; Yoneyama, M | 1 |
| Cole, MA; Kalman, BA; Pace, TW; Spencer, RL; Ward, G | 1 |
| Campion, J; Gerenu, G; Martisova, E; Milagro, FI; Ramirez, MJ; Solas, M | 1 |
| Behar-Cohen, F; Bousquet, E; Célérier, I; Curan, A; Farman, N; Jaisser, F; Jeanny, JC; Jonet, L; Offret, O; Savoldelli, M; Zhao, M | 1 |
| Korz, V; Meyer, K; Wang, H | 1 |
| Amano, T; Nakatani, Y; Takeda, H; Tsuji, M | 1 |
| Chang, HY; Chen, HT; Chen, JC; Cheng, ML; Hsiao, MC; Wu, TC; Yang, CY | 1 |
| Amano, T; Nakatani, Y; Takeda, H | 2 |
| Hattori, T; Iwase, E; Miyachi, M; Murase, T; Murohara, T; Nagata, K; Ohtake, M; Takahashi, K; Tsuboi, K | 1 |
| Ahmad, M; Huang, BS; Leenen, FH; White, RA | 1 |
| Carobrez, AP; Dal Bó, S; de Kloet, ER; Oitzl, MS; Souza, RR | 1 |
| Clark, JK; Hammond, S; Keralapurath, MM; Wagner, JJ | 1 |
| Cheng, XW; Hattori, T; Miyachi, M; Murase, T; Murohara, T; Nagata, K; Ohtake, M; Takahashi, K; Takatsu, M; Watanabe, S | 1 |
| Almada, RC; Brandão, ML; Fogaça, MV; Reis, FM | 1 |
| Gravenstein, N; Martynyuk, AE; Seubert, CN; Sumners, C; Tan, S; Vasilopoulos, T; Xu, C; Zhang, J | 1 |
| Cao, J; Ding, ZY; Duan, TT; Jing, L; Mao, RR; Richter-Levin, G; Tan, JW; Tian, M; Xu, L; Yang, YX; Yuan, Q; Zhang, X; Zhou, QX; Zhu, YY | 1 |
| Ahmad, M; Chen, A; Huang, BS; Leenen, FH; Wang, HW; White, RA | 1 |
| Aono, H; Choudhury, ME; Fujita, T; Islam, A; Mise, A; Miyanishi, K; Nishioka, R; Sugimoto, K; Takahashi, H; Takeda, H; Tanaka, J; Yano, H | 1 |
| Al-Dujaili, EA; Bailey, MA; Christensen, TH; Evans, LC; Holmes, MC; Ivy, JR; Kenyon, CJ; McNairn, JA; Menzies, RI; Mullins, JJ; Seckl, JR; Wyrwoll, C | 1 |
| Aiso, S; Hiraoka, Y; Nogami, H | 1 |
| Chapman, KE; Hadoke, PW; MacRae, VE; Rashdan, NA; Zhu, D | 1 |
| Adachi, S; Baker, ME; Katsu, Y; Oka, K; Sato, R; Sugimoto, A | 1 |
| Anderson, BM; Fitzgerald, DP; George, AJ; McNay, EC; O'Leary, KE; Osborne, DM; Vidal, MM | 1 |
| Al-Dujaili, EA; Batchen, EJ; Chapman, KE; Darroch, R; Diaz, ME; Gray, GA; Kenyon, CJ; Moran, CM; Pan, X; Richardson, RV; Rog-Zielinska, EA; Scullion, K; Thomson, AJ; Wyrzykowska, W | 1 |
| Bailey, MA; Costello, HM; Flatman, PW; Ivy, JR; Jones, NK; Mansley, MK; Peltz, TS | 1 |
| Baker, ME; Hyodo, S; Katsu, Y; Lin, X; Oana, S | 1 |
| de Azevedo Camin, N; de Barcellos Filho, PCG; Franci, CR; Traslaviña, GAA | 1 |
| Albernaz-Mariano, KA; Demarchi Munhoz, C | 1 |
| Kashefi, A; Nasrollahi, N; Raise-Abdullahi, P; Rashidy-Pour, A; Vafaei, AA | 1 |
4 review(s) available for spironolactone and corticosterone
| Article | Year |
|---|---|
Sodium retention after adrenal enucleation.
Topics: Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormone; Aldosterone; Animals; Biological Assay; Bufo marinus; Corticosterone; Desoxycorticosterone; Female; Homeostasis; Kidney; Male; Natriuresis; Nephrons; Pro-Opiomelanocortin; Rats; Regeneration; Sodium; Spironolactone; Time Factors; Urinary Bladder | 1986 |
[Problems in the surgical treatment of Cushing's disease. Our experience with bilateral adrenalectomy].
Topics: Adolescent; Adrenalectomy; Adult; Child; Corticosterone; Cortisone; Cushing Syndrome; Female; Follow-Up Studies; Humans; Hydrocortisone; Male; Middle Aged; Postoperative Care; Prednisolone; Preoperative Care; Spironolactone | 1974 |
Primary hyperaldosteronism.
Topics: Adrenal Gland Neoplasms; Aldosterone; Corticosterone; Desoxycorticosterone; Electrocardiography; Humans; Hyperaldosteronism; Hypokalemia; Kidney Diseases; Renal Artery Obstruction; Renin; Sodium; Spironolactone; Time Factors; Urea | 1974 |
[Corticosterone-producing adrenal tumor].
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Corticosterone; Diagnosis, Differential; Humans; Hypertension; Hyponatremia; Metyrapone; Mineralocorticoid Receptor Antagonists; Prognosis; Spironolactone | 2006 |
1 trial(s) available for spironolactone and corticosterone
| Article | Year |
|---|---|
Effect of spironolactone on aldosterone regulation in man.
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Corticosterone; Humans; Hydrocortisone; Male; Potassium; Renin; Sodium; Spironolactone | 1980 |
176 other study(ies) available for spironolactone and corticosterone
| Article | Year |
|---|---|
Aldosterone antagonists. 2. Synthesis and biological activities of 11,12-dehydropregnane derivatives.
Topics: Adrenalectomy; Animals; Kidney; Male; Mineralocorticoid Receptor Antagonists; Rats; Rats, Inbred Strains; Receptors, Androgen; Receptors, Mineralocorticoid; Receptors, Progesterone; Receptors, Steroid; Structure-Activity Relationship | 1987 |
Transient expression of oatp organic anion transporter in mammalian cells: identification of candidate substrates.
Topics: Anion Transport Proteins; Anions; Carrier Proteins; HeLa Cells; Hormones; Humans; Hydrogen-Ion Concentration; Serum Albumin; Sodium Chloride; Solutions; Steroids; Substrate Specificity; Sucrose; Sulfobromophthalein; Taurocholic Acid; Time Factors | 1996 |
Impact of induced fit on ligand binding to the androgen receptor: a multidimensional QSAR study to predict endocrine-disrupting effects of environmental chemicals.
Topics: Benzhydryl Compounds; Binding Sites; Diethylstilbestrol; Endocrine System; Hydrocarbons, Chlorinated; Ligands; Models, Molecular; Molecular Conformation; Phenols; Phytoestrogens; Quantitative Structure-Activity Relationship; Receptors, Androgen; Testosterone; Thermodynamics; Xenobiotics | 2005 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Convenient QSAR model for predicting the complexation of structurally diverse compounds with beta-cyclodextrins.
Topics: beta-Cyclodextrins; Hydrophobic and Hydrophilic Interactions; Organic Chemicals; Quantitative Structure-Activity Relationship | 2009 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Potent and selective steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 7, an enzyme that catalyzes the reduction of the key hormones estrone and dihydrotestosterone.
Topics: 17-Hydroxysteroid Dehydrogenases; Androstane-3,17-diol; Androstanes; Biocatalysis; Cell Line; Dihydrotestosterone; Enzyme Inhibitors; Estradiol; Estrone; Humans; Inhibitory Concentration 50; Oxidation-Reduction; Substrate Specificity | 2009 |
Modulating Mineralocorticoid Receptor with Non-steroidal Antagonists. New Opportunities for the Development of Potent and Selective Ligands without Off-Target Side Effects.
Topics: Amino Acid Sequence; Animals; Benzoxazines; Dihydropyridines; Drug Discovery; Humans; Ligands; Macrolides; Mineralocorticoid Receptor Antagonists; Models, Molecular; Oxazolidinones; Peptides; Pyrazoles; Pyrroles; Receptors, Mineralocorticoid; Structure-Activity Relationship; Sulfonamides | 2017 |
Assay and properties of 18-hydroxylation of endogenous and exogenous corticosterone in rat adrenals. Evidence for heterogeneity of 18-hydroxylase activity.
Topics: Adrenal Glands; Animals; Canrenoic Acid; Canrenone; Corticosterone; Gas Chromatography-Mass Spectrometry; Male; Mitochondria; NADPH-Ferrihemoprotein Reductase; Potassium Chloride; Rats; Spironolactone; Steroid Hydroxylases | 1979 |
[Cytochrome P-450 and transformation from 18-hydroxycorticosterone to aldosterone].
Topics: 18-Hydroxycorticosterone; Adrenal Glands; Aldosterone; Animals; Corticosterone; Cytochrome P-450 Enzyme System; Ducks; In Vitro Techniques; Male; Metyrapone; Mitochondria; Oxidation-Reduction; Spironolactone | 1979 |
Corticoid receptors in rat brain: evidence for an aldosterone receptor.
Topics: Aldosterone; Animals; Binding Sites; Brain; Corticosterone; Cytosol; Dexamethasone; Macromolecular Substances; Male; Rats; Receptors, Cell Surface; Spironolactone | 1976 |
Loci of action of regulators of aldosterone biosynthesis in isolated glomerulosa cells.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Aldosterone; Aminoglutethimide; Angiotensin II; Animals; Corticosterone; Desoxycorticosterone; Dogs; In Vitro Techniques; Potassium; Progesterone; Rats; Spironolactone | 1979 |
Ultrastructural evidence for aldosterone- and corticosterone-secreting cells in the adrenocortical tissue of the American Bullfrog (Rana catesbeiana).
Topics: Adrenal Glands; Aldosterone; Animals; Anura; Corticosterone; Dexamethasone; Hypophysectomy; Rana catesbeiana; Sodium; Spironolactone | 1977 |
The significance of elevated levels of plasma 18-hydroxycorticosterone in patients with primary aldosteronism.
Topics: 18-Hydroxycorticosterone; Adenoma; Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; Aldosterone; Corticosterone; Humans; Hyperaldosteronism; Posture; Potassium; Potassium Chloride; Renin; Spironolactone | 1979 |
Opposing effects of deoxycorticosterone and spironolactone on isoprenaline-induced myocardial infarction.
Topics: Animals; Body Weight; Corticosterone; Desoxycorticosterone; Isoproterenol; Lipids; Male; Myocardial Infarction; Organ Size; Rats; Spironolactone; Water-Electrolyte Balance | 1979 |
Physiological activity and receptor binding of 9 alpha fluorohydrocortisone.
Topics: Aldosterone; Animals; Binding, Competitive; Corticosterone; Fludrocortisone; Gluconeogenesis; Hydrocortisone; Kidney; Liver; Male; Rats; Receptors, Glucocorticoid; Receptors, Steroid; Spironolactone; Triamcinolone Acetonide | 1977 |
The role of the adrenal gland in hypertensive transgenic rat TGR(mREN2)27.
Topics: 18-Hydroxycorticosterone; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Animals; Animals, Genetically Modified; Corticosterone; Desoxycorticosterone; Enzyme Precursors; Gene Expression; Hypertension; Rats; Rats, Inbred Strains; Renin; Spironolactone | 1992 |
Central hypertensinogenic effects of glycyrrhizic acid and carbenoxolone.
Topics: Administration, Oral; Animals; Blood Pressure; Brain; Carbenoxolone; Corticosterone; Glycyrrhetinic Acid; Glycyrrhizic Acid; Hypertension; Injections, Intraventricular; Male; Rats; Rats, Sprague-Dawley; Spironolactone | 1992 |
Dietary restriction sensitizes the rat distal colon to aldosterone.
Topics: Adrenalectomy; Aldosterone; Amiloride; Animals; Biological Transport; Colon; Corticosterone; Food Deprivation; Intestinal Absorption; Rats; Sodium; Spironolactone; Starvation | 1992 |
The "mineralocorticoid-like" actions conferred on corticosterone by carbenoxolone are inhibited by the mineralocorticoid receptor (type I) antagonist RU28318.
Topics: Adrenalectomy; Aldosterone; Animals; Carbenoxolone; Corticosterone; Creatinine; Desoxycorticosterone; Male; Mineralocorticoids; Natriuresis; Potassium; Rats; Receptors, Mineralocorticoid; Receptors, Steroid; Spironolactone | 1991 |
Interference of C17-spirosteroids with late steps of aldosterone biosynthesis. Structure-activity studies.
Topics: 17-alpha-Hydroxyprogesterone; 18-Hydroxycorticosterone; Aldosterone; Animals; Corticosterone; Depression, Chemical; Hydroxyprogesterones; Male; Radioimmunoassay; Rats; Rats, Inbred Strains; Spironolactone; Structure-Activity Relationship | 1991 |
Regulatory effects of 5 beta-reduced steroids.
Topics: Aminolevulinic Acid; Animals; Chick Embryo; Chickens; Corticosterone; Cyanoketone; Cytochrome P-450 Enzyme System; Estradiol; Male; Oxidation-Reduction; Pregnanediones; Progesterone; Spironolactone; Steroids | 1991 |
[In vitro functional differentiation of hippocampal corticosterone receptors by mineralo- and glucocorticoids].
Topics: Aldosterone; Animals; Corticosterone; Evoked Potentials; Hippocampus; Mice; Mice, Inbred BALB C; Receptors, Steroid; Spironolactone | 1991 |
Properties and distribution of binding sites for the mineralocorticoid receptor antagonist [3H]ZK 91587 in brain.
Topics: Adrenalectomy; Aldosterone; Amygdala; Animals; Binding, Competitive; Brain; Corticosterone; Hippocampus; Male; Mineralocorticoid Receptor Antagonists; Mineralocorticoids; Rats; Rats, Inbred Strains; Receptors, Mineralocorticoid; Receptors, Steroid; Septum Pellucidum; Spironolactone; Tissue Distribution | 1990 |
Time-related changes in plasma adrenal steroids during treatment with spironolactone in primary aldosteronism.
Topics: Adenoma; Administration, Oral; Adrenal Gland Neoplasms; Adult; Aldosterone; Corticosterone; Desoxycorticosterone; Drug Administration Schedule; Evaluation Studies as Topic; Female; Humans; Hydrocortisone; Hyperaldosteronism; Male; Middle Aged; Mineralocorticoids; Monitoring, Physiologic; Potassium; Renin; Sodium; Spironolactone; Time Factors | 1990 |
Differential central effects of mineralocorticoid and glucocorticoid agonists and antagonists on blood pressure.
Topics: Adrenalectomy; Aldosterone; Androstanols; Animals; Blood Pressure; Brain; Corticosterone; Glucocorticoids; Injections, Intraventricular; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Mineralocorticoids; Rats; Rats, Inbred Strains; Spironolactone | 1990 |
Differentiation of frog skin active Na+ transport during metamorphosis is induced by thyroid hormone.
Topics: Aldosterone; Animals; Biological Transport, Active; Corticosterone; Electrodes; Hydrocortisone; Metamorphosis, Biological; Metyrapone; Nystatin; Rana catesbeiana; Skin; Sodium; Spironolactone; Triiodothyronine | 1990 |
Response of exocrine pancreas to corticosterone and aldosterone after adrenalectomy.
Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Amylases; Animals; Body Weight; Corticosterone; Female; Pancreas; Rats; Rats, Inbred Strains; Spironolactone | 1989 |
Aldosterone-stimulated down-regulation of both type I and type II adrenocorticosteroid receptors in mouse brain is mediated via type I receptors.
Topics: Aldosterone; Androstanols; Animals; Brain; Corticosterone; Dexamethasone; Female; Mice; Mice, Inbred Strains; Receptors, Corticotropin; Receptors, Pituitary Hormone; Spironolactone; Time Factors | 1989 |
On the role of brain mineralocorticoid (type I) and glucocorticoid (type II) receptors in neuroendocrine regulation.
Topics: Animals; Brain; Corticosterone; Estrenes; Glucocorticoids; Injections, Intraventricular; Injections, Subcutaneous; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Rats; Rats, Inbred Strains; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Receptors, Steroid; Spironolactone; Stress, Physiological | 1989 |
Modulation of angiotensin II binding sites in neuronal cultures by mineralocorticoids.
Topics: Aldosterone; Angiotensin II; Animals; Astrocytes; Brain Stem; Cells, Cultured; Corticosterone; Cycloheximide; Desoxycorticosterone; Dexamethasone; Dose-Response Relationship, Drug; Estradiol; Hypothalamus; Mineralocorticoids; Neurons; Progesterone; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Spironolactone; Testosterone | 1989 |
Corticosterone's metabolite is an agonist for Na+ transport stimulation in A6 cells.
Topics: Animals; Biological Transport, Active; Cell Line; Cell Membrane; Cell Nucleus; Computer Simulation; Corticosterone; Estrenes; Glucocorticoids; Kinetics; Membrane Potentials; Mifepristone; Models, Biological; Receptors, Glucocorticoid; Receptors, Steroid; Sodium; Spironolactone | 1988 |
ZK91587: a novel synthetic antimineralocorticoid displays high affinity for corticosterone (type I) receptors in the rat hippocampus.
Topics: Animals; Binding, Competitive; Corticosterone; Cytosol; Hippocampus; Kinetics; Male; Mineralocorticoids; Rats; Rats, Inbred Strains; Receptors, Glucocorticoid; Receptors, Steroid; Spironolactone | 1988 |
Corticosteroid regulation of Na+ and K+ transport in the rat distal colon during postnatal development.
Topics: Adrenal Cortex Hormones; Adrenalectomy; Aging; Aldosterone; Amiloride; Animals; Animals, Suckling; Colon; Corticosterone; Dexamethasone; Estrenes; Mifepristone; Potassium; Rats; Sodium; Spironolactone | 1988 |
Antiglucocorticoid RU 38486 attenuates retention of a behaviour and disinhibits the hypothalamic-pituitary adrenal axis at different brain sites.
Topics: Adrenalectomy; Animals; Behavior, Animal; Brain; Corticosterone; Dexamethasone; Dose-Response Relationship, Drug; Estrenes; Hypothalamo-Hypophyseal System; Injections, Intraventricular; Male; Memory; Mifepristone; Pituitary-Adrenal System; Rats; Rats, Inbred Strains; Receptors, Glucocorticoid; Retention, Psychology; Spironolactone | 1988 |
The reoxidation of cytochrome P-450 by paraquat inhibits aldosterone biosynthesis from 18-hydroxycorticosterone.
Topics: 18-Hydroxycorticosterone; Adrenal Glands; Aldosterone; Animals; Corticosterone; Cytochrome P-450 Enzyme System; Ducks; Kinetics; Male; Metyrapone; Mineralocorticoid Receptor Antagonists; Mitochondria; Oxidation-Reduction; Paraquat; Reference Values; Spironolactone | 1988 |
Aldosterone-induced, amiloride-inhibitable short-circuit current in the avian ileum.
Topics: Aldosterone; Amiloride; Animals; Chickens; Corticosterone; Diet, Sodium-Restricted; Electrophysiology; Ileum; Intestinal Mucosa; Mineralocorticoid Receptor Antagonists; Serous Membrane; Sodium; Spironolactone | 1987 |
Aldosterone effects on salt appetite in adrenalectomized rats.
Topics: Adrenalectomy; Aldosterone; Animals; Appetite; Brain Chemistry; Corticosterone; Drinking Behavior; Drug Interactions; Male; Mineralocorticoid Receptor Antagonists; Rats; Rats, Inbred Strains; Sodium Chloride; Spironolactone | 1986 |
Rat C6 glioma cells contain type I as well as type II corticosteroid receptors.
Topics: Adrenal Cortex Hormones; Aldosterone; Androstanols; Animals; Cell Line; Corticosterone; Desoxycorticosterone; Dexamethasone; Glioma; Progesterone; Rats; Rats, Inbred Strains; Receptors, Glucocorticoid; Spironolactone; Triamcinolone | 1985 |
The role of adrenal corticosteroids in the regulation of kidney function in the desert lizard Dipsosaurus dorsalis.
Topics: Adrenal Cortex Hormones; Aldosterone; Animals; Corticosterone; Dexamethasone; Ethanol; Glomerular Filtration Rate; Inulin; Kidney; Lizards; Natriuresis; Photometry; Sodium; Sodium Chloride; Spironolactone; Time Factors; Tritium | 1972 |
Letter: Effect of various steroids and ACTH on methyprylon plasma levels and sleeping time in rats.
Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Desoxycorticosterone; Female; Fludrocortisone; Piperidones; Pregnenolone Carbonitrile; Rats; Sleep; Spironolactone; Triamcinolone | 1973 |
Clinical investigation of the effects of adrenal corticosteroid excess on the colon.
Topics: Addison Disease; Adrenal Cortex Hormones; Adrenocortical Hyperfunction; Adult; Aldosterone; Colon; Corticosterone; Desoxycorticosterone; Dialysis; Feces; Female; Humans; Hydrocortisone; Hyperaldosteronism; Hypertension; Magnesium; Magnesium Sulfate; Male; Middle Aged; Potassium; Sodium; Spironolactone; Urea | 1969 |
On the mechanism of the inhibitory action of the spirolactone SC 9376 (aldadiene) on the production of corticosteroids in rat adrenals in vitro.
Topics: Adrenal Glands; Aldosterone; Androstanes; Animals; Cardanolides; Corticosterone; Diet; Dose-Response Relationship, Drug; Ketosteroids; Male; Mass Spectrometry; Mineralocorticoid Receptor Antagonists; Rats; Sodium; Spironolactone | 1973 |
Low renin hypertension and the adrenal cortex.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Blood Pressure; Corticosterone; Desoxycorticosterone; Diuresis; Humans; Hydrochlorothiazide; Hyperaldosteronism; Hypertension; Hypokalemia; Indoles; Male; Pyridines; Renin; Secretory Rate; Spironolactone; Sulfonic Acids | 1972 |
Subacute necrotizing encephalomyelopathy with vacuolated cells in the bone marrow.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocorticotropic Hormone; Aldosterone; Amino Acids; Arginine; Bone Marrow; Bone Marrow Cells; Child, Preschool; Corticosterone; Demyelinating Diseases; Encephalomyelitis; Female; Growth Hormone; Humans; Hydrocortisone; Magnesium; Metyrapone; Spinal Cord; Spironolactone; Vitamin B Complex | 1972 |
Spironolactone and amiloride in the treatment of low renin hyperaldosteronism and related syndromes.
Topics: Adrenocortical Hyperfunction; Amiloride; Angiotensin II; Body Water; Corticosterone; Diuretics; Extracellular Space; Humans; Hyperaldosteronism; Hypertension; Plasma Volume; Potassium; Pyrazines; Renin; Secretory Rate; Sodium; Spironolactone; Urea | 1973 |
Prevention of indomethacin-induced intestinal ulcers by various catatoxic steroids.
Topics: Adrenal Cortex Hormones; Animals; Antitoxins; Chemical Phenomena; Chemistry; Corticosterone; Ethylestrenol; Female; Indomethacin; Intestinal Diseases; Norsteroids; Oxandrolone; Peritonitis; Prednisolone; Pregnanediones; Progesterone; Rats; Spironolactone; Triamcinolone; Ulcer | 1970 |
Adaptation to the natriuretic actions of hydrochlorothiazide, frusemide and amiloride, by rats.
Topics: Adaptation, Physiological; Adrenal Glands; Adrenalectomy; Aldosterone; Amiloride; Animals; Corticosterone; Diuresis; Diuretics; Female; Furosemide; Hydrochlorothiazide; Juxtaglomerular Apparatus; Natriuresis; Potassium; Pyrazines; Rats; Renin; Sodium; Sodium Chloride; Spironolactone; Time Factors | 1972 |
Plasma aldosterone in essential hypertension with low renin activity.
Topics: Aldosterone; Body Weight; Corticosterone; Cushing Syndrome; Furosemide; Humans; Hydrochlorothiazide; Hypertension; Hypertension, Renal; Kidney Failure, Chronic; Metabolism, Inborn Errors; Mixed Function Oxygenases; Posture; Potassium; Radioimmunoassay; Renin; Spironolactone | 1974 |
Experimental studies on the carbonic anhydrase activity. IX. The mode of action of adrenocortical steroids, especially aldosterone, on the carbonic anhydrase in mice and rats.
Topics: Acetazolamide; Adrenal Cortex Hormones; Adrenal Glands; Aldosterone; Animals; Carbonic Anhydrases; Corticosterone; Hydrocortisone; Kidney; Liver; Male; Mice; Pancreas; Rats; Spironolactone | 1967 |
Interactions of spironolactone and hydrochlorothiazide with aspirin in the rat and dog.
Topics: Aldosterone; Animals; Aspirin; Corticosterone; Diuresis; Diuretics; Dogs; Drug Interactions; Female; Hydrochlorothiazide; Kidney; Male; Mineralocorticoids; Natriuresis; Potassium; Rats; Rats, Inbred Strains; Spironolactone | 1972 |
[Effect of hormones on physical and chemical properties of connective- and supporting tissue. 1].
Topics: Acetates; Adrenalectomy; Age Factors; Aldosterone; Animals; Body Weight; Connective Tissue; Corticosterone; Depression, Chemical; Desoxycorticosterone; Dihydrotachysterol; Epiphyses; Estradiol; Female; Femur; Guinea Pigs; Hormones; Hydrocortisone; Male; Mice; Prednisolone; Progesterone; Rabbits; Rats; Sex Factors; Spironolactone; Stimulation, Chemical; Stress, Physiological; Succinates; Tail; Tendons; Testosterone | 1969 |
The syndrome of primary aldosteronism.
Topics: 17-Hydroxycorticosteroids; Adenoma; Adolescent; Adrenal Gland Neoplasms; Adult; Aldosterone; Blood Urea Nitrogen; Body Weight; Carbon Dioxide; Chlorides; Chromium; Corticosterone; Diet; Female; Humans; Hydrogen-Ion Concentration; Hyperaldosteronism; Hyperplasia; Male; Middle Aged; Potassium; Sodium; Spironolactone; Triamterene; Urine | 1970 |
Effect of adrenal steroid hormones on the response of the toad's urinary bladder to vasopressin.
Topics: Aldosterone; Animals; Anura; Biological Transport; Carbon Isotopes; Chlorides; Corticosterone; Desoxycorticosterone; Dexamethasone; Glucose; Potassium; Sodium; Spironolactone; Urinary Bladder; Vasopressins; Water | 1969 |
Non-tumorous "primary" aldosteronism: II. Type not relieved by glucocorticoid.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Glands; Adrenalectomy; Adult; Aldosterone; Blood Pressure; Corticosterone; Desoxycorticosterone; Dexamethasone; Diet; Glucocorticoids; Humans; Hyperaldosteronism; Kidney Function Tests; Male; Middle Aged; Potassium; Secretory Rate; Spironolactone; Water-Electrolyte Balance | 1969 |
Adrenal-renal function in water snakes Natrix cyclopion.
Topics: Adrenal Glands; Adrenalectomy; Animals; Chlorides; Corticosterone; Diuresis; Female; Glomerular Filtration Rate; Kidney; Male; Osmosis; Potassium; Snakes; Sodium; Spironolactone; Triamterene; Water | 1969 |
Evidence that an acute increase in glomerular filtration has little effect on sodium excretion in the dog unless extracellular volume is expanded.
Topics: Absorption; Aminohippuric Acids; Animals; Biological Transport; Corticosterone; Dexamethasone; Dogs; Dopamine; Glomerular Filtration Rate; Inulin; Kidney Tubules; Potassium; Sodium; Spironolactone; Vasopressins | 1967 |
Effect of spironolactone on electrolytes, renin, ACTH and corticosteroids in the rat.
Topics: Adrenocorticotropic Hormone; Aldosterone; Animals; Corticosterone; Diet; Diet, Sodium-Restricted; Feces; Male; Potassium; Rats; Rats, Inbred Strains; Renin; Sodium; Spironolactone | 1984 |
Pharmacology of the steroid regulation of transmitter choice in cultured rat sympathetic ganglia.
Topics: Aldosterone; Androstanols; Animals; Choline O-Acetyltransferase; Corticosterone; Cortodoxone; Ganglia, Sympathetic; Progesterone; Rats; Rats, Inbred Strains; Spironolactone; Tyrosine 3-Monooxygenase | 1984 |
Effect of spironolactone administration on plasma and urinary aldosterone in man and the rat.
Topics: 17-Ketosteroids; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Corticosterone; Humans; Hydrocortisone; Male; Rats; Renin; Species Specificity; Spironolactone | 1980 |
19-Hydroxyandrostenedione: evidence for a new class of sodium-retaining and hypertensinogenic steroids.
Topics: Aldosterone; Androstenedione; Animals; Blood Pressure; Corticosterone; Desoxycorticosterone; Drug Interactions; Potassium; Rats; Renin; Sodium; Spironolactone | 1983 |
Steroid-induced protein synthesis in giant-toad (Bufo marinus) urinary bladders. Correlation with natriferic activity.
Topics: Aldosterone; Animals; Biological Transport; Bufo marinus; Corticosterone; Dexamethasone; Electrophoresis, Polyacrylamide Gel; Female; In Vitro Techniques; Protein Biosynthesis; Sodium; Spironolactone; Urinary Bladder | 1984 |
The metabolism of aldosterone in kidney.
Topics: Adrenalectomy; Aldosterone; Animals; Cell Membrane; Cell Nucleus; Chromatography, High Pressure Liquid; Corticosterone; Kidney; Male; Progesterone; Rats; Rats, Inbred Strains; Spironolactone | 1983 |
Influence of spironolactone on aldosterone metabolism in hyperaldosteronism.
Topics: Aldosterone; Corticosterone; Humans; Hyperaldosteronism; Kinetics; Progesterone; Renin; Spironolactone | 1980 |
Plasma aldosterone levels in the female tortoise Testudo hermanni Gmelin in different experimental conditions.
Topics: Aldosterone; Animals; Corticosterone; Diet; Female; Furosemide; Potassium; Sodium; Spironolactone; Turtles | 1982 |
Hormonal control of osmoregulation in the Chelonia. I. The effects of prolactin and interrenal steroids in freshwater chelonians.
Topics: Aldosterone; Animals; Corticosterone; Female; Glomerular Filtration Rate; Hypophysectomy; Magnesium; Male; Potassium; Prolactin; Sodium; Spironolactone; Turtles; Water-Electrolyte Balance | 1980 |
Opposing roles of type I and type II adrenal steroid receptors in hippocampal long-term potentiation.
Topics: Adrenal Cortex Hormones; Adrenalectomy; Aldosterone; Animals; Corticosterone; Dentate Gyrus; Electric Stimulation; Hippocampus; Hormone Antagonists; Long-Term Potentiation; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Neural Pathways; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Steroid; Spironolactone | 1995 |
Cardiovascular effects of microinjection of corticoids and antagonists into the rostral ventrolateral medulla in rats.
Topics: Aldosterone; Animals; Blood Pressure; Cardiovascular System; Corticosterone; Female; Glucocorticoids; Heart Rate; Male; Medulla Oblongata; Microinjections; Mifepristone; Mineralocorticoids; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Rats, Wistar; Spironolactone | 1995 |
Consequence of long-term exposure to corticosterone or dexamethasone on ethanol consumption in the adrenalectomized rat, and the effect of type I and type II corticosteroid receptor antagonists.
Topics: Adrenalectomy; Alcohol Drinking; Animals; Body Weight; Corticosterone; Dexamethasone; Drinking; Drug Implants; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Organ Size; Rats; Rats, Wistar; Receptors, Steroid; Sodium Chloride; Spironolactone | 1995 |
Mineralocorticoid antagonist inhibits stress-induced blood pressure response after repeated daily warming.
Topics: Adrenocorticotropic Hormone; Aldosterone; Animals; Blood Pressure; Corticosterone; Heart Rate; Hot Temperature; Male; Mineralocorticoid Receptor Antagonists; Rats; Rats, Wistar; Spironolactone; Stress, Physiological | 1994 |
Sensitivity of the circadian rhythm of kainic acid-induced convulsion susceptibility to manipulations of corticosterone levels and mineralocorticoid receptor binding.
Topics: Animals; Circadian Rhythm; Corticosterone; Hippocampus; Kainic Acid; Male; Mice; Mineralocorticoid Receptor Antagonists; Receptors, Mineralocorticoid; Seizures; Spironolactone; Time Factors | 1994 |
Role of glucocorticoid in the development of glycyrrhizin-induced hypertension.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adrenal Glands; Adrenalectomy; Aldosterone; Animals; Blood Pressure; Corticosterone; Desoxycorticosterone; Dexamethasone; Glucocorticoids; Glycyrrhetinic Acid; Glycyrrhizic Acid; Hydroxysteroid Dehydrogenases; Hypertension; Male; Mineralocorticoids; Potassium; Rats; Rats, Wistar; Renin; Spironolactone | 1994 |
The effect of corticosterone on reactivity to spatial novelty is mediated by central mineralocorticosteroid receptors.
Topics: Adrenalectomy; Adrenocorticotropic Hormone; Animals; Corticosterone; Exploratory Behavior; Locomotion; Male; Mifepristone; Rats; Rats, Wistar; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spatial Behavior; Spironolactone | 1994 |
Direct and indirect effects of carbenoxolone on responses to glucocorticoids and noradrenaline in rat aorta.
Topics: Adrenalectomy; Animals; Aorta; Carbenoxolone; Corticosterone; Glucocorticoids; In Vitro Techniques; Male; Mifepristone; Norepinephrine; Rats; Rats, Wistar; Spironolactone; Vasoconstriction | 1994 |
Corticosterone is a preferable ligand for measuring rat brain corticosteroid receptors: competition by RU 28362 and RU 26752 for dexamethasone binding in rat hippocampal cytosol.
Topics: Androstanols; Animals; Binding, Competitive; Brain; Corticosterone; Cytosol; Dexamethasone; Hippocampus; Ligands; Male; Osmolar Concentration; Rats; Receptors, Steroid; Spironolactone | 1993 |
11-Dehydrocorticosterone in the presence of carbenoxolone is a more potent sodium retainer than corticosterone.
Topics: Adrenalectomy; Animals; Carbenoxolone; Corticosterone; Creatinine; Male; Mineralocorticoid Receptor Antagonists; Natriuresis; Potassium; Rats; Rats, Sprague-Dawley; Spironolactone | 1993 |
A role for the mineralocorticoid receptor in a rapid and transient suppression of hippocampal 5-HT1A receptor mRNA by corticosterone.
Topics: Adrenalectomy; Animals; Corticosterone; Densitometry; Dose-Response Relationship, Drug; Gene Expression Regulation; Hippocampus; In Situ Hybridization; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Rats; Rats, Wistar; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Receptors, Serotonin; RNA, Messenger; Spironolactone | 1995 |
The memory-facilitating effects of the competitive NMDA-receptor antagonist CGP 37849 are steroid-sensitive, whereas its memory-impairing effects are not.
Topics: 2-Amino-5-phosphonovalerate; Aldosterone; Aminoglutethimide; Animals; Corticosterone; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Male; Memory; Mice; Mineralocorticoid Receptor Antagonists; Spironolactone | 1996 |
Facilitation of ethanol consumption by intracerebroventricular infusions of corticosterone.
Topics: Adrenalectomy; Alcohol Drinking; Animals; Corticosterone; Drinking; Injections, Intraventricular; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Rats; Rats, Wistar; Receptors, Glucocorticoid; Spironolactone | 1996 |
Effects of corticosteroids on parameters related to Na+ transport by amphibian renal distal cells (A6) in culture.
Topics: Adrenal Cortex Hormones; Aldosterone; Animals; Biological Transport; Cell Line; Corticosterone; Dexamethasone; Electrophysiology; Epithelium; Glucocorticoids; Hormone Antagonists; Kidney Tubules, Distal; Mifepristone; Mineralocorticoid Receptor Antagonists; Ouabain; Receptors, Glucocorticoid; Sodium; Sodium-Potassium-Exchanging ATPase; Spironolactone; Xenopus laevis | 1996 |
Effect of glucocorticoids on the adrenocortical axis responses to electrical stimulation of the amygdala and the ventral noradrenergic bundle.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Amygdala; Animals; Corticosterone; Corticotropin-Releasing Hormone; Dexamethasone; Electric Stimulation; Feedback; Hypothalamo-Hypophyseal System; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Pituitary-Adrenal System; Rats; Rats, Inbred Strains; Spironolactone | 1997 |
Aldosterone rapidly represses protein kinase C activity in neonatal rat cardiomyocytes in vitro.
Topics: Aldosterone; Analysis of Variance; Animals; Animals, Newborn; Calcium; Cells, Cultured; Corticosterone; Desoxycorticosterone; Dose-Response Relationship, Drug; Fibroblasts; Myocardium; Protein Kinase C; Rats; Rats, Sprague-Dawley; Spironolactone; Tetradecanoylphorbol Acetate; Tritium | 1997 |
Role of adrenal steroids in stimulating ammonium excretion during acute metabolic acidosis.
Topics: Acidosis; Adrenal Cortex Hormones; Adrenal Glands; Ammonium Chloride; Animals; Corticosterone; Hormone Antagonists; Hydrogen-Ion Concentration; Hydroxysteroid Dehydrogenases; Kidney Tubules, Collecting; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley; Spironolactone; Steroids | 1997 |
Facilitation of feedback inhibition through blockade of glucocorticoid receptors in the hippocampus.
Topics: Adrenocorticotropic Hormone; Animals; Circadian Rhythm; Corticosterone; Feedback; Hippocampus; Hypothalamus; Injections, Intraventricular; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Pituitary-Adrenal System; Rats; Rats, Wistar; Receptors, Glucocorticoid; Spironolactone | 1997 |
A role for brain glucocorticoid receptors in contextual fear conditioning: dependence upon training intensity.
Topics: Animals; Brain; Conditioning, Psychological; Corticosterone; Electroshock; Fear; Hormone Antagonists; Injections, Intraventricular; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Rats; Rats, Wistar; Receptors, Glucocorticoid; Spironolactone | 1998 |
Regulation of hippocampal theta activity by corticosterone: opposing functions of mineralocorticoid and glucocorticoid receptors.
Topics: Analysis of Variance; Animals; Corticosterone; Electric Stimulation; Hippocampus; Hypothalamus, Posterior; Male; Mifepristone; Rats; Rats, Inbred Strains; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone; Theta Rhythm; Time Factors | 1998 |
Involvement of glucocorticoids in the reorganization of the amphibian immune system at metamorphosis.
Topics: Aldosterone; Animals; Apoptosis; Corticosterone; Glucocorticoids; Hormone Antagonists; Lymphocyte Activation; Lymphocytes; Metamorphosis, Biological; Mifepristone; Spironolactone; Spleen; Thymus Gland; Xenopus laevis | 1997 |
Evidence for mineralocorticoid receptor facilitation of glucocorticoid receptor-dependent regulation of hypothalamic-pituitary-adrenal axis activity.
Topics: Adrenocorticotropic Hormone; Animals; Circadian Rhythm; Corticosterone; Drug Combinations; Hormone Antagonists; Hypothalamo-Hypophyseal System; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Pituitary-Adrenal System; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Receptors, Steroid; Spironolactone | 1998 |
A second enzyme protecting mineralocorticoid receptors from glucocorticoid occupancy.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Animals; Aryl Hydrocarbon Hydroxylases; Cell Line; Corticosterone; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Electric Conductivity; Glucocorticoids; Hydroxysteroid Dehydrogenases; Isoenzymes; Kidney; Macrolides; Mineralocorticoid Receptor Antagonists; Oxidoreductases, N-Demethylating; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone; Steroid Hydroxylases; Xenopus laevis | 1998 |
Repeated blockade of mineralocorticoid receptors, but not of glucocorticoid receptors impairs food rewarded spatial learning.
Topics: Animals; Corticosterone; Food; Hippocampus; Hormone Antagonists; Male; Maze Learning; Mifepristone; Mineralocorticoid Receptor Antagonists; Rats; Rats, Wistar; Receptors, Glucocorticoid; Reward; Space Perception; Spironolactone | 1998 |
Steroid specificity of the putative DHB receptor: evidence that the receptor is not 11betaHSD.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Animals; Carbenoxolone; Cell Nucleus; Cells, Cultured; CHO Cells; Colon; Corticosterone; Cricetinae; Culture Media, Conditioned; Hydroxysteroid Dehydrogenases; Intestinal Mucosa; Male; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Spironolactone; Substrate Specificity; Transfection | 1998 |
Corticosterone and 11-dehydrocorticosterone stimulate Na,K-ATPase gene expression in vascular smooth muscle cells.
Topics: Animals; Aorta; Cells, Cultured; Corticosterone; Dactinomycin; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Male; Mifepristone; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium-Potassium-Exchanging ATPase; Spironolactone | 1998 |
Corticosterone is permissive to the anxiolytic effect that results from the blockade of hippocampal mineralocorticoid receptors.
Topics: Adrenalectomy; Animals; Anti-Anxiety Agents; Anti-Inflammatory Agents; Anxiety; Corticosterone; Cortisone; Dexamethasone; Hippocampus; Male; Microinjections; Mifepristone; Mineralocorticoid Receptor Antagonists; Rats; Receptors, Glucocorticoid; Spironolactone | 1998 |
Regulation of hippocampal glucocorticoid receptor gene transcription and protein expression in vivo.
Topics: Adrenal Glands; Animals; Corticosterone; Gene Expression Regulation; Hippocampus; Male; Mineralocorticoid Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; RNA, Heterogeneous Nuclear; RNA, Messenger; Spironolactone; Stress, Physiological; Transcriptional Activation | 1998 |
Piracetam facilitates long-term memory for a passive avoidance task in chicks through a mechanism that requires a brain corticosteroid action.
Topics: Adrenal Cortex Hormones; Animals; Animals, Newborn; Avoidance Learning; Brain; Chickens; Corticosterone; Female; Hormone Antagonists; Male; Memory; Mifepristone; Mineralocorticoid Receptor Antagonists; Nootropic Agents; Piracetam; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone | 1998 |
Evaluation of RU28318 and RU40555 as selective mineralocorticoid receptor and glucocorticoid receptor antagonists, respectively: receptor measures and functional studies.
Topics: Adrenalectomy; Animals; Biological Assay; Corticosterone; Dexamethasone; Hippocampus; Hormone Antagonists; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Pituitary Gland; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone | 1998 |
Corticosterone modifies muscarinic receptor immunoreactivity in rat hippocampus.
Topics: Acetylcholine; Adrenalectomy; Animals; Corticosterone; Hippocampus; Immunohistochemistry; Male; Mifepristone; Rats; Rats, Wistar; Receptors, Muscarinic; Spironolactone | 1999 |
The amygdala: site of genomic and nongenomic arousal of aldosterone-induced sodium intake.
Topics: Aldosterone; Amygdala; Animals; Appetite; Arousal; Corticosterone; Desoxycorticosterone; Genome; Hormone Antagonists; Injections; Injections, Intraventricular; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Oligonucleotides, Antisense; Rats; Rats, Sprague-Dawley; Receptors, GABA; Receptors, Mineralocorticoid; Sodium; Spironolactone | 2000 |
Micromolar concentrations of steroids and of aldosterone antagonists inhibit the outwardly rectifying chloride channel with different kinetics.
Topics: Aldosterone; Anti-Inflammatory Agents; Canrenone; Chloride Channels; Corticosterone; Cytosol; Dose-Response Relationship, Drug; Estradiol; HT29 Cells; Humans; Hydrocortisone; Ion Channel Gating; Kinetics; Lipids; Mineralocorticoid Receptor Antagonists; Patch-Clamp Techniques; Progesterone; Spironolactone; Testosterone | 2000 |
The active phase-related increase in corticosterone and aggression are linked.
Topics: Aggression; Animals; Behavior, Animal; Circadian Rhythm; Corticosterone; Darkness; Kinetics; Light; Male; Mineralocorticoid Receptor Antagonists; Rats; Rats, Wistar; Receptors, Mineralocorticoid; Spironolactone; Territoriality | 2000 |
Effects of spironolactone on systolic blood pressure in experimental diabetic rats.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Aldosterone; Animals; Corticosterone; Diabetes Mellitus, Experimental; Hydroxysteroid Dehydrogenases; Male; Rats; Rats, Sprague-Dawley; Receptors, Mineralocorticoid; RNA, Messenger; Spironolactone; Streptozocin; Systole | 2000 |
Glucocorticoid modulates Na+/H+ exchange activity in vascular smooth muscle cells by nongenomic and genomic mechanisms.
Topics: Animals; Cells, Cultured; Corticosterone; Cycloheximide; Cytoskeleton; Dactinomycin; Dose-Response Relationship, Drug; Genome; Hydrogen-Ion Concentration; Intracellular Membranes; Male; Mifepristone; Muscle, Smooth, Vascular; Nucleic Acid Synthesis Inhibitors; Protein Kinase C; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Steroid; RNA, Messenger; Sodium-Hydrogen Exchangers; Spironolactone | 2000 |
Selective blockade of the mineralocorticoid receptor impairs hypothalamic-pituitary-adrenal axis expression of habituation.
Topics: Animals; Corticosterone; Drug Combinations; Habituation, Psychophysiologic; Hormone Antagonists; Hypothalamo-Hypophyseal System; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Pituitary-Adrenal System; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Restraint, Physical; Spironolactone; Stress, Physiological | 2000 |
Cardiac aldosterone production in genetically hypertensive rats.
Topics: Adrenalectomy; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiomegaly; Corticosterone; Cytochrome P-450 CYP11B2; Heart Ventricles; Hypertension; In Vitro Techniques; Mineralocorticoid Receptor Antagonists; Myocardium; Organ Size; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin; RNA, Messenger; Spironolactone | 2000 |
Endogenous glucocorticoids play a positive regulatory role in the anti-keyhole limpet hemocyanin in vivo antibody response.
Topics: Administration, Oral; Adrenalectomy; Animals; Antigens; Corticosterone; Dexamethasone; Drug Combinations; Hemocyanins; Hormone Antagonists; Hypertrophy; Immunoglobulin G; Immunoglobulin Isotypes; Immunoglobulin M; Immunosuppressive Agents; Injections, Intraperitoneal; Injections, Subcutaneous; Interferon-gamma; Male; Mifepristone; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Spironolactone; Spleen; Thymus Gland | 2001 |
Adrenocorticosteroid receptor blockade and excitotoxic challenge regulate adrenocorticosteroid receptor mRNA levels in hippocampus.
Topics: Animals; Cell Count; Corticosterone; Excitatory Amino Acid Agonists; Hippocampus; Hormone Antagonists; Kainic Acid; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Pyramidal Cells; Rats; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; RNA, Messenger; Spironolactone | 2001 |
Glucocorticoid and mineralocorticoid receptors are involved in the facilitation of anxiety-like response induced by restraint.
Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents; Anxiety; Corticosterone; Dexamethasone; Injections, Intraventricular; Male; Metyrapone; Mifepristone; Mineralocorticoid Receptor Antagonists; Rats; Rats, Wistar; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Restraint, Physical; Spironolactone; Stress, Psychological | 2001 |
Psychological stress increases hippocampal mineralocorticoid receptor levels: involvement of corticotropin-releasing hormone.
Topics: Adrenalectomy; Animals; Cold Temperature; Corticosterone; Corticotropin-Releasing Hormone; Dexamethasone; Environment; Glucocorticoids; Hippocampus; Hypothalamo-Hypophyseal System; Immunohistochemistry; Injections, Intraventricular; Male; Mineralocorticoid Receptor Antagonists; Peptide Fragments; Pituitary-Adrenal System; Pyramidal Cells; Radioligand Assay; Rats; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone; Stress, Psychological; Swimming | 2001 |
Aldosterone breakthrough during angiotensin II receptor antagonist therapy in stroke-prone spontaneously hypertensive rats.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Body Weight; Corticosterone; Dexamethasone; Dose-Response Relationship, Drug; Gene Expression Regulation; Hypertension; Imidazoles; Male; Natriuretic Peptide, Brain; Prodrugs; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA, Messenger; Spironolactone; Stroke; Tetrazoles; Time Factors | 2002 |
Traumatic brain injury regulates adrenocorticosteroid receptor mRNA levels in rat hippocampus.
Topics: Adrenocorticotropic Hormone; Animals; Brain Injuries; Corticosterone; Hippocampus; Hormone Antagonists; In Situ Hybridization; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; RNA, Messenger; Spironolactone | 2002 |
Selective aldosterone blockade prevents angiotensin II/salt-induced vascular inflammation in the rat heart.
Topics: Adrenalectomy; Aldosterone; Angiotensin II; Animals; Body Weight; Coronary Disease; Coronary Vessels; Corticosterone; Cyclooxygenase 2; Diuresis; Drinking; Eating; Eplerenone; Heart; Hypertension; Isoenzymes; Macrophages; Male; Mineralocorticoid Receptor Antagonists; Myocardium; Necrosis; Organ Size; Osteopontin; Potassium; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Renin; Sialoglycoproteins; Sodium; Sodium Chloride; Spironolactone; Vasculitis | 2002 |
[CHRONIC IDIOPATHIC HYPOKALEMIA WITH HYPERKALIURIA IN CHILDREN].
Topics: Adrenal Glands; Aldosterone; Blood Platelet Disorders; Blood Platelets; Child; Corticosterone; Dwarfism; Fatigue; Genetics, Medical; Humans; Hyperlipidemias; Hypocalcemia; Hypokalemia; Hyponatremia; Kidney; Pathology; Polyuria; Potassium; Spironolactone; Thirst; Urine | 1964 |
BIOLOGICAL ACTION OF ALDOSTERONE IN VITRO.
Topics: Adrenal Cortex Hormones; Aldosterone; Animals; Anura; Biological Transport; Bufonidae; Cell Membrane Permeability; Corticosterone; Desoxycorticosterone; Hydrocortisone; In Vitro Techniques; Mucous Membrane; Pharmacology; Research; Sodium; Sodium Isotopes; Spironolactone; Urinary Bladder | 1964 |
DECREASED EFFECTIVENESS OF ALDOSTERONE ON ACTIVE SODIUM TRANSPORT BY THE ISOLATED TOAD BLADDER IN THE PRESENCE OF OTHER STEROIDS.
Topics: Aldosterone; Animals; Anura; Biological Transport; Biological Transport, Active; Bufonidae; Corticosterone; Estradiol; Hydrocortisone; Permeability; Pharmacology; Progesterone; Research; Sodium; Spironolactone; Urinary Bladder | 1964 |
Glucocorticoid receptor blockade disinhibits pituitary-adrenal activity during the stress hyporesponsive period of the mouse.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Animals, Newborn; Corticosterone; Hippocampus; Hypothalamus; In Situ Hybridization; Mice; Mineralocorticoid Receptor Antagonists; Pituitary Gland, Anterior; Pro-Opiomelanocortin; Receptors, Glucocorticoid; RNA, Messenger; Spironolactone; Temperature; Time Factors | 2005 |
Blockage of glucocorticoid, but not mineralocorticoid receptors prevents the persistent increase in circulating basal corticosterone concentrations following stress in the rat.
Topics: Adaptation, Physiological; Animals; Circadian Rhythm; Corticosterone; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone; Stress, Physiological | 2005 |
Disruption of mineralocorticoid receptor function increases corticosterone responding to a mild, but not moderate, psychological stressor.
Topics: Adrenalectomy; Animals; Corticosterone; Handling, Psychological; Hypothalamo-Hypophyseal System; Male; Mineralocorticoid Receptor Antagonists; Pituitary-Adrenal System; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Restraint, Physical; Spironolactone; Stress, Physiological | 2005 |
Corticosterone increases damage and cytosolic calcium accumulation associated with ethanol withdrawal in rat hippocampal slice cultures.
Topics: Animals; Calcium; Central Nervous System Depressants; Corticosterone; Cytosol; Ethanol; Female; Fluorescent Dyes; Hippocampus; Hormone Antagonists; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Organ Culture Techniques; Organic Chemicals; Propidium; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, N-Methyl-D-Aspartate; Spironolactone; Substance Withdrawal Syndrome | 2005 |
Aldosterone increases T-type calcium channel expression and in vitro beating frequency in neonatal rat cardiomyocytes.
Topics: Aldosterone; Animals; Animals, Newborn; Calcium Channels, L-Type; Calcium Channels, T-Type; Corticosterone; Glucocorticoids; Heart Ventricles; Mifepristone; Mineralocorticoid Receptor Antagonists; Myocardial Contraction; Myocytes, Cardiac; Patch-Clamp Techniques; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Spironolactone; Stimulation, Chemical | 2005 |
Cultured embryonic hippocampal neurons deficient in glucocorticoid (GC) receptor: a novel model for studying nongenomic effects of GC in the neural system.
Topics: Animals; Cell Culture Techniques; Cell Survival; Corticosterone; Culture Media, Serum-Free; Cycloheximide; Hippocampus; Hormone Antagonists; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mifepristone; Mineralocorticoid Receptor Antagonists; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neurons; p38 Mitogen-Activated Protein Kinases; PC12 Cells; Phosphorylation; Protein Synthesis Inhibitors; Rats; Receptors, Glucocorticoid; RNA, Messenger; Serum Albumin, Bovine; Spironolactone | 2005 |
Roles of mineralocorticoid and glucocorticoid receptors in the regulation of progenitor proliferation in the adult hippocampus.
Topics: Adrenalectomy; Analysis of Variance; Animals; Bromodeoxyuridine; Cell Count; Cell Proliferation; Corticosterone; Drug Interactions; Hippocampus; Hormone Antagonists; Immunohistochemistry; Ki-67 Antigen; Male; Mifepristone; Neurons; Organ Size; Rats; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone; Statistics as Topic; Stem Cells; Thymus Gland | 2005 |
Stimulation of testosterone production in rat Leydig cells by aldosterone is mineralocorticoid receptor mediated.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 11-beta-Hydroxysteroid Dehydrogenase Type 2; Aldosterone; Animals; Binding Sites; Carbenoxolone; Corticosterone; Drug Synergism; In Vitro Techniques; Leydig Cells; Male; Mineralocorticoid Receptor Antagonists; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Mineralocorticoid; RNA, Messenger; Spironolactone; Testosterone | 2005 |
Mineralocorticoid receptor antagonism attenuates cardiac hypertrophy and failure in low-aldosterone hypertensive rats.
Topics: Aldosterone; Animals; Cardiac Output, Low; Cardiomegaly; Cardiotonic Agents; Coronary Vessels; Corticosterone; Echocardiography; Eplerenone; Hypertension; Male; Mineralocorticoid Receptor Antagonists; Myocardium; Osmolar Concentration; Oxidative Stress; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Dahl; Receptor, Angiotensin, Type 1; Receptors, Mineralocorticoid; Renin; RNA, Messenger; Spironolactone; Vasculitis; Ventricular Function; Ventricular Remodeling | 2006 |
Mineralocorticoid receptors and cardiovascular damage: it's not just aldosterone.
Topics: Aldosterone; Animals; Cardiac Output, Low; Cardiomegaly; Cardiotonic Agents; Corticosterone; Eplerenone; Humans; Hypertension; Mineralocorticoid Receptor Antagonists; Receptors, Mineralocorticoid; Renin; Spironolactone; Ultrasonography | 2006 |
Central mineralocorticoid receptors are indispensable for corticosterone-induced impairment of memory retrieval in rats.
Topics: Animals; Anisomycin; Behavior, Animal; Corticosterone; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Interactions; Hormone Antagonists; Male; Maze Learning; Memory Disorders; Mifepristone; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Receptors, Mineralocorticoid; Spironolactone; Swimming | 2007 |
Translational research goes both ways: lessons from clinical studies.
Topics: Aldosterone; Amino Acid Sequence; Antihypertensive Agents; Biomedical Research; Clinical Trials as Topic; Corticosterone; Dose-Response Relationship, Drug; Eplerenone; Genetic Predisposition to Disease; Heart Failure; Humans; Hypertension; Receptors, Mineralocorticoid; Spironolactone | 2008 |
Sub-chronic stimulation of glucocorticoid receptor impairs and mineralocorticoid receptor protects cytosolic Ca2+ responses to glucose in pancreatic beta-cells.
Topics: Aldosterone; Animals; Calcium; Corticosterone; Cytosol; Dose-Response Relationship, Drug; Female; Glucose; Insulin; Insulin Secretion; Insulin-Secreting Cells; Mifepristone; Pertussis Toxin; Pregnancy; Rats; Rats, Wistar; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone | 2008 |
Aldosterone-induced changes in the cardiac L-type Ca(2+) current can be prevented by antioxidants in vitro and are absent in rats on low salt diet.
Topics: Acetylcysteine; Action Potentials; Aldosterone; Animals; Antioxidants; Calcium Channels, L-Type; Corticosterone; Diet, Sodium-Restricted; Electrocardiography; Heart Rate; Heart Ventricles; Kinetics; Male; Mineralocorticoid Receptor Antagonists; Myocytes, Cardiac; Oxidation-Reduction; Potassium; Rats; Rats, Sprague-Dawley; Receptors, Mineralocorticoid; Spironolactone; Time Factors | 2008 |
Cocaine decreases the expression of PSA-NCAM protein and attenuates long-term potentiation via glucocorticoid receptors in the rat dentate gyrus.
Topics: Animals; Bromodeoxyuridine; Cell Count; Cell Proliferation; Cocaine; Cocaine-Related Disorders; Corticosterone; Dentate Gyrus; Dopamine Uptake Inhibitors; Down-Regulation; Ki-67 Antigen; Long-Term Potentiation; Male; Memory; Memory Disorders; Metyrapone; Mifepristone; Mineralocorticoid Receptor Antagonists; Neural Cell Adhesion Molecule L1; Neurons; Rats; Rats, Wistar; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Sialic Acids; Spironolactone | 2008 |
Glucocorticoid signaling and exercise-induced downregulation of the mineralocorticoid receptor in the induction of adult mouse dentate neurogenesis by treadmill running.
Topics: Adrenalectomy; Adult Stem Cells; Analysis of Variance; Animals; Brain-Derived Neurotrophic Factor; Cell Differentiation; Corticosterone; Dentate Gyrus; Doublecortin Domain Proteins; Doublecortin Protein; Gene Expression Regulation; Hormone Antagonists; Male; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; Mineralocorticoid Receptor Antagonists; Neurons; Neuropeptides; Physical Conditioning, Animal; Receptor, trkB; Receptors, Mineralocorticoid; Running; Signal Transduction; Spironolactone; Statistics, Nonparametric | 2008 |
Effect of single treatment with the antihypertensive drug eplerenone on hormone levels and anxiety-like behaviour in rats.
Topics: Adrenocorticotropic Hormone; Aldosterone; Animals; Antihypertensive Agents; Anxiety; Behavior, Animal; Corticosterone; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Eplerenone; Hormones; Male; Maze Learning; Rats; Rats, Wistar; Renin; Spironolactone | 2008 |
Stressor and glucocorticoid-dependent induction of the immediate early gene kruppel-like factor 9: implications for neural development and plasticity.
Topics: Animals; Brain; Cell Line; Corticosterone; Gene Expression; Glucocorticoids; Immunohistochemistry; Kruppel-Like Transcription Factors; Mifepristone; Mineralocorticoid Receptor Antagonists; Neurons; Polymerase Chain Reaction; Radioimmunoassay; Receptors, Glucocorticoid; Spironolactone; Stress, Physiological; Transfection; Xenopus laevis | 2009 |
Role of central nervous system aldosterone synthase and mineralocorticoid receptors in salt-induced hypertension in Dahl salt-sensitive rats.
Topics: Aldosterone; Animals; Blood Pressure; Corticosterone; Cytochrome P-450 CYP11B2; Disease Models, Animal; Enzyme Inhibitors; Heart Rate; Hippocampus; Hypertension; Hypothalamus; Male; Mineralocorticoid Receptor Antagonists; Rats; Rats, Inbred Dahl; Receptors, Mineralocorticoid; Sodium; Sodium Chloride, Dietary; Spironolactone; Steroid Hydroxylases; Time Factors | 2009 |
Activation of glucocorticoid receptors increases 5-HT2A receptor levels.
Topics: Analysis of Variance; Animals; Autoradiography; Corticosterone; Fluorobenzenes; Gene Expression Regulation; Hippocampus; Hormone Antagonists; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mifepristone; Mineralocorticoid Receptor Antagonists; Piperidines; Protein Binding; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Glucocorticoid; Serotonin Plasma Membrane Transport Proteins; Spironolactone; Tissue Culture Techniques; Tritium | 2009 |
Corticosteroids operate as a switch between memory systems.
Topics: Animals; Caudate Nucleus; Corticosterone; Hippocampus; Memory; Mice; Mineralocorticoid Receptor Antagonists; Mineralocorticoids; Receptors, Mineralocorticoid; Spironolactone; Stress, Physiological | 2010 |
Eplerenone, a selective mineralocorticoid receptor blocker, exerts anxiolytic effects accompanied by changes in stress hormone release.
Topics: Adrenal Cortex; Aldosterone; Animals; Anti-Anxiety Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Corticosterone; Eplerenone; Exploratory Behavior; Hippocampus; Male; Mineralocorticoid Receptor Antagonists; Neuronal Plasticity; Oxytocin; Pituitary Gland, Posterior; Random Allocation; Rats; Rats, Wistar; Spironolactone; Stress, Psychological; Vasopressins | 2010 |
Corticosterone up-regulates expression and function of norepinephrine transporter in SK-N-BE(2)C cells.
Topics: Animals; Anti-Inflammatory Agents; Cell Line, Transformed; Cell Line, Tumor; Corticosterone; Dose-Response Relationship, Drug; Hormone Antagonists; Humans; Mifepristone; Neuroblastoma; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Rats; RNA, Messenger; Spironolactone; Time Factors; Tritium; Up-Regulation | 2010 |
Acute stress impairs hippocampal mossy fiber-CA3 long-term potentiation by enhancing cAMP-specific phosphodiesterase 4 activity.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adrenalectomy; Animals; Anti-Inflammatory Agents; Biophysical Phenomena; Colforsin; Corticosterone; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Electric Stimulation; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; Mineralocorticoid Receptor Antagonists; Mossy Fibers, Hippocampal; Phosphodiesterase Inhibitors; Spironolactone; Stress, Psychological; Synaptosomes; Xanthines | 2010 |
Stress within the postseizure time window inhibits seizure recurrence.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents; Anticonvulsants; Circadian Rhythm; Corticosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Hormone Antagonists; Kindling, Neurologic; Mifepristone; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Secondary Prevention; Seizures; Spironolactone; Stress, Physiological; Time Factors | 2010 |
11beta-hydroxysteroid dehydrogenase type 1 deficiency prevents memory deficits with aging by switching from glucocorticoid receptor to mineralocorticoid receptor-mediated cognitive control.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Aging; Analysis of Variance; Animals; Cognition; Corticosterone; Hippocampus; Infusions, Intraventricular; Male; Maze Learning; Memory; Mice; Mice, Knockout; Mineralocorticoid Receptor Antagonists; Radioimmunoassay; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone | 2011 |
Antidepressant-like effects of mineralocorticoid but not glucocorticoid antagonists in the lateral septum: interactions with the serotonergic system.
Topics: Animals; Antidepressive Agents; Clomipramine; Corticosterone; Drug Interactions; Fenclonine; Hydroxyindoleacetic Acid; Immobility Response, Tonic; Male; Microinjections; Mifepristone; Mineralocorticoid Receptor Antagonists; Rats; Rats, Wistar; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Septum of Brain; Serotonin; Spironolactone | 2011 |
Brief neck restraint stress enhances long-term potentiation and suppresses long-term depression in the dentate gyrus of the mouse.
Topics: Animals; Corticosterone; Dentate Gyrus; Enzyme Inhibitors; Hormone Antagonists; Long-Term Potentiation; Long-Term Synaptic Depression; Male; Metyrapone; Mice; Mice, Inbred C57BL; Mifepristone; Mineralocorticoid Receptor Antagonists; Neck; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Restraint, Physical; Spironolactone; Synaptic Transmission | 2011 |
Adipocyte-derived factors regulate vascular smooth muscle cells through mineralocorticoid and glucocorticoid receptors.
Topics: 3T3-L1 Cells; Adipocytes; Aldosterone; Angiotensin II; Animals; Blotting, Western; Cells, Cultured; Corticosterone; Culture Media, Conditioned; Eplerenone; Fadrozole; Fibronectins; Hormone Antagonists; Mice; Mice, Inbred C57BL; Mifepristone; Mineralocorticoid Receptor Antagonists; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-bcl-2; Receptor, Angiotensin, Type 1; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone | 2011 |
Glucocorticoids are critical regulators of dendritic spine development and plasticity in vivo.
Topics: Age Factors; Animals; Corticosterone; Dendritic Spines; Dexamethasone; Dose-Response Relationship, Drug; Glucocorticoids; Hormone Antagonists; Luminescent Proteins; Mice; Mice, Transgenic; Microscopy, Fluorescence, Multiphoton; Mifepristone; Mineralocorticoid Receptor Antagonists; Motor Cortex; Neuronal Plasticity; Receptors, Steroid; Somatosensory Cortex; Spironolactone; Time Factors | 2011 |
Blockade of mineralocorticoid and glucocorticoid receptors reverses stress-induced motor impairments.
Topics: Aldosterone; Animals; Blood Glucose; Corticosterone; Dexamethasone; Female; Hormone Antagonists; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Motor Activity; Motor Skills; Rats; Receptors, Glucocorticoid; Restraint, Physical; Spironolactone; Stress, Physiological | 2011 |
Opposing roles of glucocorticoid receptor and mineralocorticoid receptor in trimethyltin-induced cytotoxicity in the mouse hippocampus.
Topics: Aldosterone; Animals; Corticosterone; Hippocampus; Mice; Mineralocorticoid Receptor Antagonists; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone; Trimethyltin Compounds | 2012 |
Acute exposure to a novel stressor further reduces the habituated corticosterone response to restraint in rats.
Topics: Animals; Behavior, Animal; Corticosterone; Feedback, Physiological; Habituation, Psychophysiologic; Hormone Antagonists; Hypothalamo-Hypophyseal System; Injections; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Pituitary-Adrenal System; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Restraint, Physical; Spironolactone; Stress, Psychological; Time Factors | 2001 |
Mechanisms involved in BACE upregulation associated to stress.
Topics: Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Cell Line, Tumor; Corticosterone; DNA Methylation; Humans; Hypothalamo-Hypophyseal System; Male; MAP Kinase Kinase 4; Maternal Deprivation; Mice; Mice, Inbred C57BL; Mineralocorticoid Receptor Antagonists; Peptides; Phosphorylation; Pituitary-Adrenal System; Rats; Rats, Wistar; Spironolactone; Stress, Psychological; Up-Regulation | 2012 |
Mineralocorticoid receptor is involved in rat and human ocular chorioretinopathy.
Topics: Adult; Aldosterone; Animals; Central Serous Chorioretinopathy; Choroid; Corticosterone; Eplerenone; Humans; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Rats; Receptors, Mineralocorticoid; Retina; Signal Transduction; Small-Conductance Calcium-Activated Potassium Channels; Spironolactone; Treatment Outcome; Vasodilation; Vasodilator Agents; Visual Acuity | 2012 |
Stress induced hippocampal mineralocorticoid and estrogen receptor β gene expression and long-term potentiation in male adult rats is sensitive to early-life stress experience.
Topics: Age Factors; Animals; Azacitidine; Corticosterone; Cyclofenil; Decitabine; Dentate Gyrus; DNA Methylation; DNA Modification Methylases; Eplerenone; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Gene Expression; Hippocampus; Long-Term Potentiation; Male; Maternal Deprivation; Mineralocorticoid Receptor Antagonists; Promoter Regions, Genetic; Rats; Rats, Wistar; Receptors, Androgen; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone; Stress, Psychological; Testosterone; Up-Regulation | 2013 |
Corticosterone suppresses the proliferation of BV2 microglia cells via glucocorticoid, but not mineralocorticoid receptor.
Topics: Animals; Anti-Inflammatory Agents; Cell Line; Cell Proliferation; Corticosterone; L-Lactate Dehydrogenase; Membrane Potential, Mitochondrial; Mice; Microglia; Mifepristone; Mineralocorticoid Receptor Antagonists; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone | 2012 |
Mineralocorticoid receptor antagonist spironolactone prevents chronic corticosterone induced depression-like behavior.
Topics: Animals; Behavior, Animal; Corticosterone; Depression; Hippocampus; Hydroxyindoleacetic Acid; Hypothalamus; Male; Mice; Mineralocorticoid Receptor Antagonists; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Serotonin; Serotonin Plasma Membrane Transport Proteins; Spironolactone; Tryptophan Hydroxylase | 2013 |
Corticosterone suppresses the proliferation of RAW264.7 macrophage cells via glucocorticoid, but not mineralocorticoid, receptor.
Topics: Animals; Cell Line; Cell Proliferation; Corticosterone; Hormone Antagonists; Macrophages; Membrane Potential, Mitochondrial; Mice; Mifepristone; Mineralocorticoid Receptor Antagonists; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone | 2013 |
Glucocorticoid-induced hypertension and cardiac injury: effects of mineralocorticoid and glucocorticoid receptor antagonism.
Topics: Animals; Atrophy; Blood Pressure; Corticosterone; Disease Models, Animal; Fibrosis; Heart Diseases; Hypertension; Inflammation Mediators; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Myocardium; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone; Time Factors; Ventricular Dysfunction, Left; Ventricular Function, Left | 2013 |
Role of brain corticosterone and aldosterone in central angiotensin II-induced hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Brain; Corticosterone; Cytochrome P-450 CYP11B2; Dose-Response Relationship, Drug; Eplerenone; Fadrozole; Heart Rate; Hypertension; Male; Mineralocorticoid Receptor Antagonists; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Mineralocorticoid; Spironolactone | 2013 |
Paradoxical mineralocorticoid receptor-mediated effect in fear memory encoding and expression of rats submitted to an olfactory fear conditioning task.
Topics: Animals; Conditioning, Psychological; Corticosterone; Fear; Fludrocortisone; Male; Memory; Mineralocorticoid Receptor Antagonists; Motor Activity; Olfactory Perception; Rats; Rats, Wistar; Receptors, Mineralocorticoid; Spironolactone | 2014 |
Cocaine- or stress-induced metaplasticity of LTP in the dorsal and ventral hippocampus.
Topics: Animals; Cocaine; Corticosterone; Dopamine Uptake Inhibitors; Drug Administration Schedule; Excitatory Postsynaptic Potentials; Hippocampus; Hormone Antagonists; In Vitro Techniques; Long-Term Potentiation; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Motor Activity; Naltrexone; Rats; Rats, Sprague-Dawley; Spironolactone; Stress, Psychological | 2014 |
Glucocorticoids activate cardiac mineralocorticoid receptors in adrenalectomized Dahl salt-sensitive rats.
Topics: Adrenalectomy; Animals; Blood Pressure; Collagen Type I; Collagen Type III; Corticosterone; Disease Models, Animal; Glucocorticoids; Hypertension; Male; Mineralocorticoid Receptor Antagonists; Myocytes, Cardiac; NADPH Oxidases; Oxidative Stress; Rats; Rats, Inbred Dahl; Receptors, Mineralocorticoid; Renin-Angiotensin System; RNA, Messenger; Sodium Chloride, Dietary; Spironolactone; Time Factors; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling | 2014 |
Rapid Activation of Glucocorticoid Receptors in the Prefrontal Cortex Mediates the Expression of Contextual Conditioned Fear in Rats.
Topics: Animals; Conditioning, Psychological; Corticosterone; Enzyme Inhibitors; Fear; Freezing Reaction, Cataleptic; Hormone Antagonists; Male; Metyrapone; Mifepristone; Prefrontal Cortex; Proto-Oncogene Proteins c-fos; Rats, Wistar; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone | 2016 |
Anesthesia with sevoflurane in neonatal rats: Developmental neuroendocrine abnormalities and alleviating effects of the corticosteroid and Cl(-) importer antagonists.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Animals, Newborn; Anxiety; Bumetanide; CA1 Region, Hippocampal; Chloride Channels; Corticosterone; Excitatory Postsynaptic Potentials; Female; Male; Maternal Deprivation; Methyl Ethers; Neurosecretory Systems; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Reflex, Startle; Sevoflurane; Sex Characteristics; Spironolactone | 2015 |
Despair-associated memory requires a slow-onset CA1 long-term potentiation with unique underlying mechanisms.
Topics: Animals; CA1 Region, Hippocampal; Corticosterone; Depression; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Immunoblotting; Ketamine; Long-Term Potentiation; Male; Memory; Mineralocorticoid Receptor Antagonists; Phosphorylation; Quinoxalines; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glucocorticoid; Receptors, N-Methyl-D-Aspartate; Spironolactone; Stress, Psychological; Swimming | 2015 |
Role of brain aldosterone and mineralocorticoid receptors in aldosterone-salt hypertension in rats.
Topics: Aldosterone; Animals; Arterial Pressure; Corticosterone; Cytochrome P-450 CYP11B2; Drinking Behavior; Eplerenone; Fadrozole; Hypertension; Male; Mineralocorticoid Receptor Antagonists; Neurons; Paraventricular Hypothalamic Nucleus; Rats; Rats, Wistar; Receptors, Mineralocorticoid; RNA, Messenger; Sodium Chloride; Spironolactone; Subfornical Organ; Supraoptic Nucleus | 2016 |
Treadmill exercise ameliorates ischemia-induced brain edema while suppressing Na⁺/H⁺ exchanger 1 expression.
Topics: Acid Sensing Ion Channel Blockers; Animals; Aquaporin 4; Brain Edema; Cells, Cultured; Corticosterone; Cytokines; Disease Models, Animal; Exercise Therapy; Functional Laterality; Gene Expression Regulation; Infarction, Middle Cerebral Artery; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Nerve Tissue Proteins; Neuroglia; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers; Spironolactone; Time Factors | 2016 |
Conditional Deletion of Hsd11b2 in the Brain Causes Salt Appetite and Hypertension.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Animals; Baroreflex; Corticosterone; Craving; Dexamethasone; Drinking Behavior; Genes, Synthetic; Hypertension; Mice; Mice, Inbred C57BL; Mice, Knockout; Mineralocorticoid Excess Syndrome, Apparent; Mineralocorticoid Receptor Antagonists; Nephrons; Nerve Tissue Proteins; Nestin; Neurons; Potassium; Receptors, Mineralocorticoid; Reflex, Abnormal; RNA, Messenger; Sodium Chloride, Dietary; Solitary Nucleus; Spironolactone | 2016 |
Estradiol and corticosterone stimulate the proliferation of a GH cell line, MtT/S: Proliferation of growth hormone cells.
Topics: Animals; Cell Line; Cell Proliferation; Corticosterone; Estradiol; Estrogen Receptor Antagonists; Estrogens; Fulvestrant; Glucocorticoids; Growth Hormone; Hormone Antagonists; Mifepristone; Mineralocorticoid Receptor Antagonists; Rats; Real-Time Polymerase Chain Reaction; RNA, Messenger; Serum Albumin, Bovine; Somatotrophs; Spironolactone | 2016 |
A novel role for the mineralocorticoid receptor in glucocorticoid driven vascular calcification.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Apoptosis; Corticosterone; Disease Models, Animal; Eplerenone; Flow Cytometry; Glucocorticoids; Mice; Mice, Inbred C57BL; Mifepristone; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphates; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; RNA, Messenger; Spironolactone; Vascular Calcification | 2016 |
Corticosterone Inhibits the Proliferation of C6 Glioma Cells via the Translocation of Unphosphorylated Glucocorticoid Receptor.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cell Survival; Corticosterone; Glioma; Hormone Antagonists; Membrane Potential, Mitochondrial; Mifepristone; Rats; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone | 2016 |
Corticosteroid and progesterone transactivation of mineralocorticoid receptors from Amur sturgeon and tropical gar.
Topics: Aldosterone; Animals; Corticosterone; Cortodoxone; Desoxycorticosterone; Fish Proteins; Fishes; Humans; Hydrocortisone; Phylogeny; Progesterone; Receptors, Mineralocorticoid; Spironolactone; Transcriptional Activation | 2016 |
Context-dependent memory following recurrent hypoglycaemia in non-diabetic rats is mediated via glucocorticoid signalling in the dorsal hippocampus.
Topics: Animals; Corticosterone; Glucocorticoids; Hippocampus; Hypoglycemia; Male; Mifepristone; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, N-Methyl-D-Aspartate; Spironolactone | 2017 |
Glucocorticoid receptor alters isovolumetric contraction and restrains cardiac fibrosis.
Topics: Animals; Corticosterone; Female; Fibrosis; Male; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Myocardial Contraction; Myocardium; Myocytes, Cardiac; Myosin Heavy Chains; Nonmuscle Myosin Type IIB; Receptors, Glucocorticoid; Sex Factors; Spironolactone; Ventricular Function, Left | 2017 |
Glucocorticoid receptor activation stimulates the sodium-chloride cotransporter and influences the diurnal rhythm of its phosphorylation.
Topics: Adrenalectomy; Animals; Circadian Rhythm; CLOCK Proteins; Corticosterone; Kidney; Male; Mice; Mice, Inbred C57BL; Mifepristone; Mineralocorticoid Receptor Antagonists; Phosphorylation; Receptors, Glucocorticoid; Sodium Chloride Symporters; Spironolactone | 2019 |
Aldosterone and dexamethasone activate African lungfish mineralocorticoid receptor: Increased activation after removal of the amino-terminal domain.
Topics: Aldosterone; Animals; Corticosterone; Cortodoxone; Desoxycorticosterone; Dexamethasone; Eplerenone; Fish Proteins; Fishes; Gene Expression; Hydrocortisone; Kinetics; Progesterone; Protein Domains; Protein Engineering; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Recombinant Proteins; Spironolactone; Triamcinolone | 2022 |
Early post-stress administration of MR or GR antagonist in adolescent female rats restored anxiogenic-like behavior and modified the HPA axis response in the adulthood.
Topics: Animals; Anxiety; Corticosterone; Corticotropin-Releasing Hormone; Female; Glucocorticoids; Hypothalamo-Hypophyseal System; Mifepristone; Mineralocorticoid Receptor Antagonists; Pituitary-Adrenal System; Rats; Receptors, Glucocorticoid; Spironolactone; Stress, Psychological | 2022 |
The infralimbic mineralocorticoid blockage prevents the stress-induced impairment of aversive memory extinction in rats.
Topics: Animals; Corticosterone; Fear; Glucocorticoids; Male; Memory Disorders; Mineralocorticoids; Rats; Rats, Wistar; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone | 2022 |
Corticosterone injection into the dorsal and ventral hippocampus impairs fear memory reconsolidation in a time-dependent manner in rats.
Topics: Animals; Corticosterone; Fear; Hippocampus; Male; Mifepristone; Rats; Rats, Wistar; Receptors, Glucocorticoid; Spironolactone | 2023 |